Focus: Development of the Neural Crest
The primary aim of our research group is to elucidate the mechanism that underlies the development of the Neural Crest. We would like to know how Neural Crest cells acquire their identity within the ectoderm and how their migration and differentiation is controlled.
Model system: zebrafish and frog
We study neural crest development in zebrafish and frog ( Xenopus laevis) embryos as these two animal models offer several complementary advantages. Zebrafish embryos are transparent and the migration of the Neural Crest is easy to visualize. In addition it is a system suitable for genetic studies. Xenopus embryos are bigger and easier to manipulate.