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Cell and Developmental Biology

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CDB Special Seminar - Dr Anna Franz - 29 June 2018

Start: Jun 29, 2018 1:00:00 PM
End: Jun 29, 2018 2:00:00 PM

Title: "Drosophila adipocytes actively migrate to skin wounds to drive repair and fight infection"
Speaker: Dr Anna Franz - Research Associate, University of Bristol (research profile)
Venue: 249 Seminar Room, Medical Sciences Building
Host: Professor David Whitmore (email)

CDB Seminar Series - Professor Benedikt Berninger - 19 July 2018

Start: Jul 19, 2018 1:00:00 PM
End: Jul 19, 2018 2:00:00 PM

Title: "Engineering neurogenesis for the postnatal brain”
Speaker: Professor Benedikt Berninger - Institute of Physiological Chemistry of the University Medical Centerof the Johannes Gutenberg University Mainz (lab page)
Venue: G29, JZ Young LT, Anatomy Building (map)
Host: Dr Richard Poole (email)
Abstract: We explore the possibilities of generating new neurons where natural neurogenesis has ceased to occur, such as the postnatal or adult cerebral cortex. The approach we have taken is of lineage reprogramming glia or other brain-resident cells into induced neurons.  Toward this end, we force the expression of developmentally relevant transcription factors to induce a neurogenic program. In this talk, I will discuss our efforts (1) to induce neurogenesis from glial cells in the postnatal mouse cortex in vivo, and (2) to decipher the molecular and cellular trajectory of adult human brain pericytes undergoing conversion into neurons.