Cell and Developmental Biology


CDB Events

Seminar - Professor Didier Trono - 20 October 2017

Start: Oct 20, 2017 1:00:00 PM
End: Oct 20, 2017 2:00:00 PM

Title: Transposable elements, their domesticators and the species-specificity of human biology
Speaker: Professor Didier Trono - School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Switzerland (research profile)
Venue: Cruciform LT2 (map)
Host: Dr Helen Rowe (email)

CDB Seminar Series - Dr Sara Benedetti - 26 October 2017

Start: Oct 26, 2017 1:00:00 PM
End: Oct 26, 2017 2:00:00 PM

Speaker: Dr Sara Benedetti, Dr Tedesco's lab
Title: Reversible immortalisation allows genetic correction of human skeletal muscle progenitors and generation of novel human artificial chromosomes for Duchenne muscular dystrophy
Venue: Anatomy Gavin de Beer LT (map)

CDB Seminar Series - 16 November 2017

Start: Nov 16, 2017 1:00:00 PM
End: Nov 16, 2017 2:00:00 PM

Speaker: John Nichols, Professor Jonathan Chubb lab
Title: Cell and molecular transitions of dedifferentiation
Venue: Anatomy Gavin de Beer LT (map)

The Developmental Neurobiology Club - 22 November 2017

Start: Nov 22, 2017 5:15:00 PM
End: Nov 22, 2017 7:00:00 PM

The Developmental Neurobiology Club is a seminar series that takes place four times a year, and is organised between UCL, KCL and the Crick, who host the seminars on a rotational basis.
The Club covers a broad range of topics within Neurosciences and sometimes even outside Neurosciences, despite its name. The next seminar will be taking place on Wednesday 22nd November. Everyone welcome!

Neuroscience Careers Network workshop - Grant Writing - 23 November 2017

Start: Nov 23, 2017 12:00:00 PM
End: Nov 23, 2017 3:00:00 PM

Chaired by: Professor Dmitri Rusakov (lab page) and Professer Patricia Salinas (research profile)
Venue: TBC

The aim of this three-hour session is to help Investigators improve their applications for funding, whether they are project grants or fellowships. It will be led by two senior UCL researchers, Professor Dmitri Rusakov and Professor Patricia Salinas, who have extensive experience of applying for funding and of sitting on the committees that decide which science gets funded. This is a rare opportunity to improve your 'grantsmanship' skills, gain insight into how funding committees work and to receive constructive feedback on your applications.
To participate in this workshop, each participant must provide an abstract, lay summary and full scientific proposal (it may be a preliminary application) for either a grant or fellowship application by November 8th 2017. Costings are NOT required.

Contact: Sandrine Geranton, Julie Lee or Leonor Gonçalves

The Division of Biosciences Patricia Clarke Lecture - Professor Mary Munson - 17 January 2018

Start: Jan 17, 2018 3:30:00 PM
End: Jan 17, 2018 4:30:00 PM

Title: Molecular mechanisms of cellular growth and secretion
Speaker: Professor Mary Munson - University of Massachusetts Medical School (lab page)
Venue: Darwin B40 LT (map)
Host: Professor Frances Brodsky (email)
Abstract: The regulation of vesicular traffic to precise intracellular compartments is essential for cell growth, homeostasis, signaling, cell division, and development. Membrane fusion between vesicles and their target membrane is carried out via SNARE proteins; however, additional regulatory control immediately prior to fusion is essential. The exocyst is a large, multisubunit protein complex implicated in tethering and regulation of the fusion of post-Golgi secretory vesicles with the plasma membrane, but its mechanism of action is poorly understood. We are using a multidisciplinary approach to elucidate its structure and function. Our most recent work demonstrates our groundbreaking purification method for intact yeast exocyst complexes, our genetic and biochemical dissection of the architecture of the exocyst, and the first view of the overall structure of the complex using negative stain EM. We are currently using a combination of cryoEM, crosslinking and mass spectrometry, mapping of subunits and binding partners using negative stain EM, as well as genetic, cell biological and single molecule biochemical analyses, to reveal exocyst structure and function at high resolution.
Biography: Mary Munson was a double major in Chemistry and Biology at Washington University (St. Louis), receiving her bachelor's degree in 1989. She went on to join the lab of Dr. Lynne Regan at Yale University in Molecular Biophysics and Biochemistry, and received her Ph.D. in 1996. She then joined Dr. Fred Hughson’s lab in the Department of Molecular Biology at Princeton University as a postdoctoral fellow, and was awarded both American Heart Association and NIH postdoctoral fellowships. She joined the faculty of Biochemistry and Molecular Pharmacology at the University of Massachusetts Medical School in 2001. Her multidisciplinary research lab focuses on using biochemical, structural, cell biological, microscopy and genetic studies to elucidate the structure and function of the exocyst complex, SNARE proteins and other key regulators of membrane trafficking in yeast and mammalian cells. The lab also studies a related endocytic trafficking regulator VPS45 that has been implicated in neutrophil disorders and human disease, and is currently working on developing a novel mouse model system. Furthermore, her lab is interested in elucidating components of a new RNA transport pathway from the nucleus. Along with funding from the NIH for her exocytosis research, she has also received funding from the US Department of Defense for the VPS45 project, and, was previously awarded the inaugural Bassick Family Worcester Foundation Award for the nuclear export project. In addition to her passion for research, she has also been involved with teaching and curriculum development for the Graduate School of Biomedical Science, and is the recipient of several Dean’s awards for her outstanding contributions.
For more information please visit the Munson Lab website or Mary's LinkedIn profile.