CDB Seminar Series - Dr Marc Amoyel - 27 September 2018
Sep 27, 2018 01:00 PM
End: Sep 27, 2018 02:00 PM
Abstract: Stem cells are thought to have intrinsic asymmetry such that they always give rise to themselves (self-renewal) and differentiating daughters. In fact, in many cases, stem cells constitute a population of cells, where some cells self-renew at the expense of others, and all cells compete to stay in their supportive environment, called the niche. We study this process in the Drosophila testis stem cell niche, focusing on what makes a stem cell better or less able than its neighbours to stay in the niche and self-renew. I will present ongoing work in the lab that explores the roles of the cell cycle in regulating niche homeostasis both autonomously and non-autonomously and discuss other questions we are pursuing in the lab.