Meet the members of the Future Targeted Healthcare Manufacturing Hub, based across six leading universities and eight university schools and departments
Index
Directors
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| Director of Strategy- Position: Professor of Biochemical Engineering, Dean of Faculty of Engineering Sciences
- Expertise: Creation of whole bioprocess models and the use of these to gain process insights and understanding.
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| Co-Director: User Engagement and Translation- Grand Challenge Lead:
Digital decisional tools for transforming supply chain management for targeted medicines - Position: Professor of Bioprocess Systems Engineering,
Head of The Department of Biochemical Engineering at UCL - Expertise: Bioprocess Decisional Tools, Bioprocess Economics,
Drug Development Cost Modelling, Capacity planning,
Portfolio Management, Risk Analysis,
Multi-Criteria Decision-Making,
Multi-Objective Simulation & Optimisation,
Chemometrics
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| Co-Director: Community Engagement and Training- Grand Challenge Lead:
Digitally-driven manufacturing and analytical platforms for targeted medicines - Position: Professor of Biochemical Engineering and Biotechnology,
UCL Biochemical Engineering - Expertise: Routes to improve the stability and activity
of biocatalytic enzymes and therapeutic proteins,
for ease of manufacture, formulation and delivery to patients
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ATMP Manufacturing
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| Co-Investigator- Position: Associate Professor in Bioprocessing of Regenerative, Cellular and Gene Therapy
UCL Biochemical Engineering - Expertise: Bioprocessing and translation of advanced cell and gene therapies from the lab-scale to clinical and commercial scales
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| Co-Investigator- Position: Professor of Manufacturing for Cell and Gene Therapies
Loughborough University School of Mechanical, Electrical and Manufacturing Engineering - Expertise: Production systems and processes for cell-based products;
Translation to commercial manufacture and clinical use;
Automated and scaled production;
Measurement systems for process control and quality release;
defining indicators of cell product quality.
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| Co-Investigator- Position: Professor of Bioprocess Microfluidics
UCL Biochemical Engineering - Expertise: Translation of bioprocessing concepts into microfluidic systems (or Lab-on-a-chip systems);
Use of advanced microfabrication techniques for polymers (rapid prototyping), glass and silicon
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| Researcher- UCL Biochemical Engineering
- Training: Master in Biotechnology; PhD in Immunology, research fellow positions in immunotherapy.
GMP and ATIMPs manufacture management for cancer patients. - Expertise: Cancer immunotherapy using viral vectors
to scale up, validate and manufacture gene-modified T cells
(TCR and Chimeric Antigen Receptors) for paediatric
and B cell cancers.
GMP production management of Gene and Cell Therapy (GCT) /ATIMPs production for cancer patients.
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Cell-Free Synthesis Experimental Research
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| Co-Investigator- Position: Professor of Bioprocess Analysis
UCL Biochemical Engineering - Expertise: Bioprocess analysis; Speed and capabilities of the analytical techniques used
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| Researcher- UCL Biochemical Engineering
- Training: MEng in Chemical Engineering,
EngD in Biochemical Engineering - Expertise: Cell-free synthesis of biomolecules.
Additionally, viral vaccine / vector purification and process simulation
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Co-Formulation, Nanoencapsulation and Analytics
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| Co-Director: Community Engagement and Training- Grand Challenge Lead:
Digitally-driven manufacturing and analytical platforms for targeted medicines - Position: Professor of Biochemical Engineering and Biotechnology,
UCL Biochemical Engineering - Expertise: Routes to improve the stability and activity
of biocatalytic enzymes and therapeutic proteins,
for ease of manufacture, formulation and delivery to patients
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| Co-Investigator- Position: Professor in Analytical Bioscience
University of Nottingham School of Pharmacy - Expertise: Design, development and implementation of miniaturized analytical devices
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| Dr Valentine AnyanwuResearcher- University of Nottingham
- Training: PhD in Biochemical Engineering
- Expertise: Engineering and characterisation of novel formulations
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| Researcher- University of Nottingham School of Pharmacy
- Training: MPharm, PhD
- Expertise: Engineering and characterisation of novel formulations
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| Researcher- UCL Biochemical Engineering
- Training: PhD in Biochemical Engineering
- Expertise: cell line development, molecular biology and production of novel modalities such as extracellular vesicles
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Digital Decisional Tools: Datamining, Digital Twins
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| Co-Investigator- Position: Professor of Applied Control
University of Manchester
Department of Electronic and Electrical Engineering - Expertise: Robotics for use in Nuclear Engineering Decommissioning
Leakage and blockage detection in pipelines;
Multivariate statistical process control;
Model predictive control;
Control loop monitoring;
Monitoring and control of batch processes
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| Co-Investigator- Position: Lecturer in Digital Bioprocess Engineering
UCL Biochemical Engineering - Expertise: Advanced Data Analytics, Mathematical Modelling,
Machine learning, Process Analytical Technology, Digital Twin
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| Researcher- University of Manchester, Department of Electronic and Electrical Engineering
- Training: Electronics Engineer/ MSc Digital Signal Processing/ PhD Process Control
- Expertise: Process Control, Multivariate Analysis, Adaptive Control, Data-based Models
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| RESEARCHER - UCL Biochemical Engineering
- Training: Bachelors Industrial Biotechnology, PhD Bioprocess Engineering
- Expertise: process analytical technology, mathematical modelling, simulation, process optimization and process control
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Digital Decisional Tools: Supply Chain Management
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| CO-DIRECTOR: USER ENGAGEMENT AND TRANSLATION- Grand Challenge Lead:
Digital decisional tools for transforming supply chain management for targeted medicines - Position: Professor of Bioprocess Systems Engineering,
UCL Biochemical Engineering - Expertise: Bioprocess Decisional Tools, Bioprocess Economics,
Drug Development Cost Modelling, Capacity planning,
Portfolio Management, Risk Analysis,
Multi-Criteria Decision-Making,
Multi-Objective Simulation & Optimisation,
Chemometrics
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| Co-Investigator- Position: Head of Department of Chemical Engineering
Professor of Process Systems Engineering
Imperial College London - Expertise: Supply chain design and optimisation;
Process synthesis and development for fine chemicals, pharmaceutical and biochemical processes;
Mathematical techniques to assess and improve process safety
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| Co-Investigator- Position: Professor of Operational Research & Systems
Warwick Business School, University of Warwick, - Expertise: Optimisation under Uncertainty, Multi-Objective Optimisation, Simulation-based Optimisation
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| Co-Investigator- Position: Lecturer in Chemical Engineering
- Imperial College London Chemical Engineering
- Expertise: Decisional/computational tools, Process modelling/simulation/optimisation, Bioprocess modelling (bioreactors & separation processes)
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| Researcher- UCL Biochemical Engineering
- Training: Chemical Engineering (MEng), Biochemical Engineering (MSc, EngD)
- Expertise: Decisional tools, Process economics for mAbs and bispecifics, Chromatography process development
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| Researcher- Imperial College London
Chemical Engineering - Training: Chemical Engineer, PhD
- Expertise: Computational tools, Model-identification and parameter estimation,
Process design and optimization, Supply chain optimization, Life cycle assessment
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| Researcher- University of Warwick
Warwick Business School - Training: Industrial Engineering (BSc, MSc, Ph.D.)
- Expertise: Operations and Supply Chain Management,
Large-Scale Optimisation, Operations Research, Business Analytics
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Reimbursement, Regulatory Strategies and Policy
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| Dr Irina BrassCo-Investigator- Position: Associate Professor in Regulation, Innovation and Public Policy,
UCL Science, Technology, Engineering and Public Policy (STEaPP) - Expertise: Regulation of emerging technologies;
managing emerging risks and uncertainty of disruptive innovation;
public policy and governance
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| CO-INVESTIGATOR, INTERIM - Position: Associate Professor of Health Economics UCL Department of Applied Health Research
- Expertise: Development, assessment and translation of statistical methodology in health economics, economic evaluations alongside clinical trials and large observational studies, with particular emphasis on digital and mental health
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| Researcher- UCL Department of Applied Health Research (DAHR)
- Training: Health Economist
- Expertise: Economic evaluation alongside clinical trials, effects of specialist cancer services, health technology adoption
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| Researcher- UCL Science Technology, Engineering and Public Policy (STEaPP)
- Training: PhD, International Politics, Master's in Geography, Bachelor’s Degree in Social Sciences
Expertise: social and geographical implications of biomedical technologies, e.g. bioinformatics, neuroimaging software, bioprinting
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| IncomingPolicy Advisor- Position: Biomanufacturing Policy Advisor
- UCL Science Technology, Engineering and Public Policy (STEaPP), Policy Impact Unit
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Operations and outreach
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| | (to be appointed)Project Manager- UCL Biochemical Engineering
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| Ms Laura Pascual BuffoneResearch Finance Officer- UCL Biochemical Engineering
Position: EPSRC Project Officer and Research Finance Administrator
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| IncomingPolicy Advisor- Position: Biomanufacturing Policy Advisor
- UCL Science Technology, Engineering and Public Policy (STEaPP), Policy Impact Unit
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