UCL Department of Biochemical Engineering


Dr Sofia Simaria


Dept of Biochemical Engineering

Faculty of Engineering Science

Joined UCL
1st Sep 2008

Research summary

Sofia’s current research focuses on the development of computer-based decision-support models that capture the process-business interface of biopharmaceutical manufacture. She works in the Decisional Tools research group lead by Dr. Suzanne Farid.

Sofia has extensive experience in the development of simulation models and optimisation algorithms for improving the efficiency of assembly line production systems and since she has joined UCL she is bringing that experience into the biopharmaceutical production area. 

As part of the research team of the Centre she contributes to the development of a decision-support optimisation software tool for the bioprocessing sector that can locate the most cost-effective combination of process parameters, process sequence, formulation method and facility design under uncertainty.

She also collaborates on a TSB Technology Programme which is enabling research into decision-support tools that help devise successful business models for novel regenerative medicine therapies such as stem cells and cell-based vaccine cancer therapy.

Teaching summary

Sofia coordinates the new MEng/MSc  course module Bioprocess Systems Engineering, designed to provide students with skills in advanced modelling, optimisation and statistical techniques such that they are adequately equipped to address problems related to evaluating the cost-effectiveness and robustness of alternative bioprocess design strategies


Universidade de Aveiro
PhD, Industrial Studies | 2006
Universidade de Aveiro
MAST, Management Techniques | 2001
Universidade de Aveiro
LCT, Industrial Engineering | 1998