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UCL Department of Biochemical Engineering

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Prof Suzanne Farid

Professor of Bioprocess Systems Engineering

Dept of Biochemical Engineering

Faculty of Engineering Science

Joined UCL
1st Oct 2000

Research summary

Specialities: Bioprocess Decisional Tools, Bioprocess Economics, Drug Development Cost Modelling, Capacity planning, Portfolio Management, Risk Analysis, Multi-Criteria Decision-Making, Multi-Objective Simulation & Optimisation, Chemometrics

Suzanne Farid is Professor of Bioprocess Systems Engineering at the Advanced Centre for Biochemical Engineering at University College London (UCL). She is Co-Director of the EPSRC-funded Future Targeted Healthcare Manufacturing Hub in collaboration with industrial and academic consortia to revolutionise the delivery of cost-effective stratified protein-based and personalised cell-based therapies to patients.  She is also Director of the UCL-MedImmune Centre of Excellence on predictive multivariate decision-support tools for mammalian cell manufacturing processes. Previously she was Co-Director of the EPSRC Centre for Innovative Manufacturing in Emergent Macromolecular Therapies

She leads research on novel software-based ‘Bioprocess Decisional Tools’ to plan the best route to manufacture of new biotherapeutic candidates. More specifically, she has pioneered the design of novel algorithms at the process-business interface to facilitate cost-effective bioprocess design, capacity planning, and R&D portfolio management through to predictive tools for root cause analysis and manufacturability assessments.

These tools have been applied to strategic decisions in the development and manufacture of protein biopharmaceuticals such as monoclonal antibodies (mAbs) and of cell and gene therapies (e.g. MSCs, CAR T-cells). Examples include batch versus continuous manufacture, in-house versus contract manufacturing decisions, factory floor scheduling, centralised versus decentralised manufacture of personalised therapies, facility fit prediction and root cause analysis of deviations in critical quality attributes (CQAs). 

Funding for the above research has come from the UK EPSRC and BBSRC Research Councils, Innovate UK (previously the TSB Technology Programme) and a range of company collaborators including Medimmune, GSK, Pfizer, Eli Lilly, Bayer, Lonza Biologics, and Pall Life Sciences. In addition the Future Targeted Healthcare Manufacturing Hub is supported by a User Steering Committee of over 35 industrial users and sector organisations.

Teaching summary

Suzanne’s current teaching activities include guiding both Biochemical Engineering and Biotechnology students in their 3rd year Bioprocess Plant Design Project which involves the complete design of a bioprocess plant for the production of biotech products arising out of life science discoveries. She has driven the creation of a new research-led teaching course, Bioprocess Systems Engineering, which exposes Master’s level students to the department’s cutting-edge research in Decisional Tools.  Suzanne’s earlier teaching roles include co-ordination of the following core process engineering courses to undergraduate and MSc students: Fluid Flow & Mixing in Bioprocesses, Heat & Mass Transfer in Bioprocesses and Computer-Aided Bioprocess Engineering.

 

Suzanne also co-ordinates the department's MBI® training module on Quality by Design for Effective Bioprocess Characterisation and Validation which forms part of the department’s continual professional development (CPD) offering. She teaches on several other MBI® training modules on economic aspects of mammalian cell processes, cell therapy cost of goods analysis, single-use process economics, R&D portfolio decisions and approaches to accelerating bioprocess development.

Education

University College London
PhD, Biochemical Engineering | 2001
University College London
BEng hons, Biochemical Engineering | 1997
University College London
CLTHE_1, Academic studies in Higher Education | 03-05

Biography

Suzanne Farid is Professor of Bioprocess Systems Engineering in the UCL Department of Biochemical Engineering and Deputy Head of Department (Education). She is a Fellow of Institution of Chemical Engineers (FIChemE). 


She sits on the UK BioIndustry Association Manufacturing Advisory Committee and ISCT Business Models and Investment Sub Committee. She has been invited to chair key international conferences in emerging research fields, including the ECI Integrated Continuous Biomanufacturing Conference, and most recently to chair one of the highest profile conferences of the discipline, Recovery of Biological Products Conference XIX. She joined UCL as a Lecturer in 2001. She obtained her Bachelor’s and Ph.D. degrees in Biochemical Engineering with UCL and Lonza Biologics. 


Conference and Association Appointments

- Chair, Recovery of Biological Products Conference RXIX (2018- 2020)

- Member, Scientific Advisory Board of Competence Centre for Advanced BioProduction by Continuous Processing AdBIOPRO hosted at KTH (2018 – present)

- Member, Steering Committee of ECI Integrated Continuous Biomanufacturing Conference ICB IV (2017 – 2019)

- Member, Scientific Advisory Committee of BioProcessing Asia (BPA) Conference (2017-2018)

- Member, Organizing Committee of ECI Advancing Manufacture of Cell and Gene Therapies VI Conference (2017-2019)

- Chair, ECI Integrated Continuous Biomanufacturing Conference - ICB III (2015-2017) & ICB II (2013-2015)

- Member, BIA (BioIndustry Association) Manufacturing Advisory Committee for Bioprocessing Industries (2009 - present)

- Member, BIA (BioIndustry Association) Cell and Gene Therapy Advisory Committee (2017 - present)

- Member, ISCT (International Society for Cellular Therapy) Business Models and COGs Subcommittee (2014 - 2017); ISCT Business Models and Investment Subcommittee (2018-present)

- Member, IChemE Biochemical Engineering Subject Group (1997 - present)

- Member, MMIP / HealthTech and Medicines KTN Roadmapping Consultation for Biopharmaceuticals and ATMPs (2016-17 / 2012) 


Publications