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Research Fellow in Microbial Fermentation (EPSRC Future Biomanufacturing Research Hub). Ref:1857690

  • Grade: 7
  • Hours: Full Time
  • Salary (inclusive of London allowance): £35,965 - £43,470 per annum
  • Closing Date: 16 Feb 2020
  • Latest time for the submission of applications: 23:59

Duties and Responsibilities

The UK Engineering and Physical Sciences Research Council (EPSRC) and the Biotechnology and Biological Sciences Research Council (BBSRC) have recently funded a £10M Future Biomanufacturing Research Hub, FBRH (https://futurebrh.com/). The Hub, led by the University of Manchester, is a national centre that brings together world-leading expertise across a range of academic and industrial partners (Spokes). The focus is on developing new underpinning technologies based on Industrial Biotechnology (IB) to enable efficient, sustainable and innovative bio-based manufacturing in three key sectors: pharmaceuticals, value-added chemicals and engineering materials.

The UCL Department of Biochemical Engineering is a key Spoke focusing on the creation and scale-up of intensified bioprocess technologies and their translation into commercial biomanufacturing processes. The department is one of the leading international centres for bioprocess research in the IB field. It has excellent research facilities including synthetic biology, automation and microfluidics laboratories as well as a full-scale £30M bioprocessing pilot plant. Two FBRH posts will be based at UCL to conduct research in partnership with the wider Hub Team.

The post is available immediately for three years in the first instance and is funded by the EPSRC

Key Requirements

UCL research will address the development and scale-up of new bioprocess technologies for intensified whole cell and enzymatic bioconversion processes.

This post will explore novel industrial host organisms for large scale, commodity chemicals production. The focus will be on creation of intensified fermentation processes (fed-batch, continuous) and their control. This work will be led by Prof. Gary Lye.

Candidates will be required to hold a PhD in a relevant discipline (Biochemical, Chemical or Mechanical Engineering or the Physical Sciences) and ideally possess experience in a number of the following areas: fermentation, bioconversion, enzyme purification and immobilisation, continuous flow reactors, microfluidics, chemometrics, kinetic modelling and bioprocess scale-up. 

The post will require a high degree of interaction with project partners so excellent team-working and communication skills are required. 

The post holder will be responsible for undertaking original experimental and modelling work, reporting on project progress and the preparation and submission of research papers arising from these and related studies.

Further Details

A job description, person specifications details on how to apply for the Research Fellow in Microbial Fermentation (EPSRC Future Biomanufacturing Research Hub). Ref:1857690 can be accessed HERE.

For informal enquiries please contact Prof. Gary Lye (g.lye@ucl.ac.uk)


Research Fellow in Bioprocess Multivariate Statistics and Machine Learning. Ref:1859641

  • Grade: 7
  • Hours: Full Time
  • Salary (inclusive of London allowance): £35,965 - £43,470 per annum
  • Closing Date: 6 Mar 2020
  • Latest time for the submission of applications: 23:59

Duties and Responsibilities

To meet the many challenges in the development of advanced biotherapeutics, UCL’s Advanced Centre for Biochemical Engineering and AstraZeneca (Cambridge) have set up a joint UCL-AstraZeneca Centre of Excellence to advance the application of predictive multivariate decision-support tools in the bioprocessing sector.

An exceptional opportunity exists for a  research fellow to join the Centre of Excellence for a challenging multidisciplinary three-year programme. The postholder will be required to carry out research in the areas of data mining and of process synthesis, design, planning and optimisation. This will include leveraging experimental data with advanced data mining, multivariate statistical tools and machine learning algorithms to derive an integrated set of predictive models for whole bioprocesses. The postholder will be responsible for managing the co-ordination of associated AstraZeneca-sponsored doctoral students working on upstream and downstream operations as well as bioprocess economics and optimisation.

The post is initially for three years in the first instance and is available from 15 March 2020.

Key Requirements

The candidate will possess an in-depth knowledge of the methods of multivariate statistical analysis and visualization research techniques, mathematical optimization and modelling, evolutionary optimization and multi-objective decision-making, with some background knowledge of biochemical engineering. Experience with multiple programming languages and database packages is also essential. A PhD degree in a relevant subject area is required (e.g. Biochemical Engineering, Chemical Engineering, Industrial Engineering, Computer Science). Advanced research and project management skills are essential, as well as an ability to work in a multidisciplinary collaborative and teamwork environment with excellent interpersonal, written and verbal communication skills.

Further Details

A job description, person specifications details on how to apply for the Research Fellow in Bioprocess Multivariate Statistics and Machine Learning. Ref:1859641 post can be accessed HERE.

For informal enquiries please contact Paula Thomas: paula.thomas@ucl.ac.uk


Please visit the jobs at UCL webpage to find out about other vacancies being advertised.