Cell and Gene Therapy Bioprocessing
Focusing on taking discoveries from lab to clinic and acquiring new skills sets to achieve this.
29 April-1 May 2019
Cell and Gene Therapy is fast becoming an established field that aims to utilize the power of cell-based medicines to deliver new therapies for the 21st Century. However, translating the discovery science into manufacturable products has so far been challenging and so multi-disciplinary engineers who possess unique skills are urgently needed to address the manufacture of these complex medicinal products.
This course addresses the real-world challenges of translating discoveries to the clinic in a way that is commercially viable. A series of lectures and interactive case
studies will enable you to:
• Understand the distinctions of manufacturing cells compared with biologics
• Understand the challenges faced in advancing cell and gene therapies to clinic and the lessons learned from established companies
• Understand the impact of design and engineering considerations on cell and gene therapy manufacture
• Identify and define critical process parameters for different cell and gene therapy applications
• Knowledge and application of analytical toolsets for quality measurement
• Understand key implications to facilitate and expedite translation from laboratory to a manufacturing and clinical setting
Who should attend?
This course is intended for engineers, life scientists and clinicians working in the fields
of regenerative medicine, cell and gene therapy, who want to understand how
to address translation. The course will also provide a strong fundamental base for
life scientists and engineers from biopharma who wish to re-purpose skills for the cell and gene therapy sector.
Key Topics Include
Emphasis is on teaching through interactive problem solving case studies in small classes for effective learning.
Challenges for scaling up lentivirus
Taking cell and gene products from lab to clinic in the real world
Process considerations for universal versus personalised therapies
Analytics and monitoring where the cell is the product
A role for automation
Navigating the critical path to clinic
Addressing process economics and CoGs
Case Study: Manufacturing scale up
Case Study: Process and product analytic tools
Previous Expert Speakers
Qasim Rafiq, UCL - Module Leader
Farlan Veraitch, UCL
Suzanne Farid, UCL
Thomas Heathman, PCT, AHitachi Group Company
Julian Hanak, NightstaRx
Damian Marshall, Cell and Gene Therapy Catapult
Glyn Stacey, UK Stem Cell Bank
John Sinden, ReNeuron
For further information and bookings please contact:
T: +44 (0) 20 7679 9619 l +44 (0) 203 549 5619