Simultaneous fit of seven
concentration-response curves with the Hill equation, using
CVFIT. Results of Black & Shankley for the inhibition of
gastric secretion evoked by 5-methyl-furmethide by six different
atropine concentrations. The dashed lines show fits that are
constrained to have the same maximum, but the Hill slope (nH)
is estimated separately for each. The solid curves show fits that
are also constrained to have the same Hill slope (i.e. to be
parallel on the log scale). Download a pdf file that describes
a case study of methods of fitting the Schild equation (methods that CVFIT
can do). Technical notes about using CVFIT for such fitting can be downloaded
here CVFIT output
Pharmacology Main Page | Research | Ion channels | DC programs | Top |