Bobby

Robert Bentham

MRes/PhD student, CoMPLEX
Physics Building, Gower Street, UCL
London, WC1E 6BT
robert.bentham.11@ucl.ac.uk


About

I joined CoMPLEX, entering the MRes/PhD programm in 2011. In October 2012 I started a PhD on Bioinformatic analysis of the interface between mitochondrial biogenesis and cell death signalling pathways, supervised by Gyorgy Szabadkai and Kevin Bryson. Before coming to UCL from 2007 to 2011 I studied at Imperial College London, graduating with a MSci in Mathematics. My main academic interests are in Evolutionary Dynamics, Bioinformatics and Network Theory.


PhD work


Bioinformatic analysis of the interface between mitochondrial biogenesis and cell death signalling pathways
Supervised by Gyorgy Szabadkai and Kevin Bryson, the aim of this PhD project is to explore the transcriptional regulation of apoptotic and necrotic cell death pathways by the PGC-1 familiy of coactivators by bioinformatics and cell biology methods, in order to identify a novel pathway linking mitochondrial biogenesis and cell fate.


MRes work


CP1: Evolution of shape in Diatoms.
Supervised by Dr. Karen Page and Dr. Eileen Cox.
pdf

CP2: Bioinformatic analysis of the interface between mitochondrial biogenesis and apoptotic cell death signaling pathways in Parkinson's disease.
Supervised by Dr. Gyorgy Szabadkai and Dr. Kevin Bryson.
pdf

CP3: Perturbations of networks and the transition to cancer. Supervised by Dr. Simone Severini and Dr. Andrew Teschendorff.
pdf

MBA poster: Aposematism and Defence Mechanisms of the Nudibranch
pdf

Summer Project: The application of sparse supervised machine learning to predict sensitivity to drugs affecting the mitochondrial biogenesis pathway in cancer.
Supervised by Dr. Gyorgy Szabadkai and Dr. Kevin Bryson.
pdf