Summer Project

Investigating the applicability of LCD technology
to structured illumination microscopy

Supervisors: Guy Moss (CoMPLEX/Pharmacology),
Sally Day (Electrical Engineering)


simulated target illuminated with a shifting sine grating

Structured illumination is a technique that exploits the information in moiré fringes to improve the spatial resolution of conventional wide-field microscopy. This project is looking at ways to make this more practical by using liquid crystals to generate the illumination.

Read the project proposal.

Look at the introductory presentation (PDF).

Some notes on SI in the context of the optical transfer function, including some basic simulation results. Then the story continues with some better image recovery simulations.

Notes on a more-or-less successful experiment to test that we can actually project an illumination pattern onto a fluorescent specimen.

Download the MATLAB source code used for some of the above simulations.

Download the final project report. (This version includes corrections of some minor errors in the submitted version but is not changed in any substantive way.)