Cancer cells are very fit individuals. However, they can not form a functional organ like a colon or a lung. Can we understand the kinds of cellular properties and interactions that contribute to cancer? Can we harness them to enhance current therapies? With the help of my supervisors, Prof. Buzz Baum (UCL Molecular Cell Biology), and maverick scientist, Dr. Peter Bentley (UCL Computer Science), I intend to find some answers.
In my PhD, I am focusing on numeric aberrations in chromosome numbers, or aneuploidy: its role in the evolution of cancer and its implications in therapies. I do in vitro experiments, in silico simulations, mathematical analysis and lots of drawings. My business is to extract organizing principles from the biological complexity, and business is good.