These are two example questions from the tests of previous years. The completed papers will be marked +1 for a correct answer and -1 for an incorrect answer. There will be a total of ten questions each with 5 parts as shown and covering all the material of the course. The paper will count 10% towards the final mark for the course.
| TRUE | FALSE | ||
| 1 | Consider the following statements about mitotic cell division and mark them true or false. | ||
| a | Most human cells are diploid except for gametes which are haploid | ||
| b | A normal human cell about to divide contains 4 times the haploid DNA content. | ||
| c | The normal order of events ina mitotic division is prophase, anaphase, metaphase, telophase. | ||
| d | At metaphase a normal human cell can be seen to contain 92 chromatids. | ||
| e | At anaphase each chromosome splits into two and one arm goes to each daughter cell. | ||
| 2 | Mark the following questions about cytogenetics true or false. | ||
| a | There are no viable human autosomal monosomies. | ||
| b | Down's syndrome is caused by the presence of an extra copy of the smallest human autosome, chromosome 22. | ||
| c | The karyotype 47 XXY is that of a male with Kleinfelter's syndrome | ||
| d | Numerical abnormalities of the X and Y chromosomes can be tolerated because there are so few genes on each of these chromosomes. | ||
| e | A Robertsonian translocation involves the fusion of two chromosomes with the loss of their short arms. | ||