The PhD was awarded at the University College London, University of London in 2001, under the supervision of Professor Michael Baum
This thesis is to be read by medical professionals only.
The author is not responsible for any actions or inactions taken by anyone and alleged to be directly or indirectly related/caused by reading this thesis.
These versions are of small size so the printed figures will not be of the best quality.
(For further information please email me j.vaidya [at] ucl.ac.uk)