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Project title
In utero stem cell treatment for babies with osteogenesis imperfecta
Project description
Step 1- Optimising the isolation, expansion and differentiation of human fetal osteoblasts. Optimising the Quasi vivo system and growth of osteoblasts within to form an ‘ex vivo’ bone model.
Step 2- Comparing amniotic fluid stem cells, their conditioned medium and their extracellular vesicles for their effect on bone in the above model.
Start date
03/2017
Primary supervisor
Dr Pascale Guillot
Based at
Great Ormond Street Institute of Child Health
Links
ORCID
Research Gate