Peptide Synthesis

We use an ACT 396 Peptide Synthesiser (which has the capability to synthesise up to 96 peptides simultaneously) and the Fmoc/tBu synthesis strategy using HBTU as the coupling reagent.

There are four scales we offer routinely and all peptides are supplied HPLC purified to >95%, with an analysis report containing HPLC and Mass Analysis. Pricing is per residue with an additional setup charge and there is also a charge for Post synthetic modifications such as Acetylation, Phosphorylation , Biotinylation or Disulphide Bond formation (see below). Other synthesis scales and also conjugation of the peptide to BSA or KLH are available on request.

To Order

Please contact Carolyn to discuss your requirements and benefit from her many years experience (see below) or ask for a quote. Please fill out the relevant form from the downloads section and forward to Carolyn Hyde.

Please Note: We can only accept minimum orders of £5000.

Contact Us

Dr Carolyn Hyde
tel: 020 7679 6769
email carolyn.hyde@ucl.ac.uk

Prices

Downloads

WIBR Request form

UCL Request form. Please send an IDT with the form.

External Request form. Please send a Purchase Order with the form.

Links

Peptide Statistics Calculator

PepSoc Homepage

Association of Biomolecular Resource Facilities Homepage

Publications

Mascagni P., Hyde C.B., Charalambous M.A., Welham K.J., J. Chem. Soc. Perkin Trans II 1987 p323 – 327. The Use of Crown Ethers in Peptide Chemistry: Part 1. Syntheses of Amino Acid Complexes with the Cyclic Polyether 18-Crown-6 and their Oligomerisation in DCC - containing Solutions.

Hyde C.B., Welham K.J., Mascagni P., J. Chem. Soc. Perkin Trans II 1989 p2011 - 2015. The Use of Crown Ethers in Peptide Chemistry: Part 2. Syntheses of Dipeptide Complexes with the Cyclic Polyether 18-Crown-6 and their Derivatisation with DMSO.

Hyde C.B., Mascagni P., Tet. Letters 1990 p399 - 402. The Use of Crown Ethers in Peptide Chemistry: Part 3. Synthesis of an Enkephalin Derivative Using 18-Crown-6 as a Non-Covalent Amino Protecting Group.

Bedford J., Hyde C., Johnson T., Jun W., Owen D., Quibell M., Sheppard R.C., Int. J. Peptide Protein Res. 1992 40 p300 - 307 Amino Acid Structure and “Difficult Sequences” in Solid Phase Peptide Synthesis.

Hyde C., Johnson T., Sheppard R.C., J. Chem. Commun. 1992 p1573 - 1575. Internal Aggregation during Solid Phase Peptide Synthesis. Dimethyl Sulfoxide as a Powerful Dissociating Solvent.

Hyde C., Johnson T., Sheppard R.C., Peptides 1992. Schneider C. H. and Eberle A. N. Eds. p314 - 315. A Simple ‘No Compromise’ Method for Multiple Peptide Synthesis.

Hyde C., Johnson T., Owen D., Quibell M., Sheppard R. Int. J. Pept. Protein Res. 1994 43 p431 - 440. Some 'difficult sequences' made easy. A study of interchain association in solid phase peptide synthesis.

Hyde C., Johnson T., Owen D., Quibell M., Sheppard R. Innovation and Perspectives in Solid Phase Synthesis 1994. Ed. R.Epton Mayflower Worldwide. p29 - 38. 'Difficult Sequences' made easy. Backbone Protection in Solid Phase Peptide Synthesis.

Cammish L., Hyde C., Johnson T., Sheppard R., Innovation and Perspectives in Solid Phase Synthesis 1994. Ed. R.Epton Mayflower Worldwide. p257 - 258. A Versatile System for Multiple Peptide Synthesis.

Hyde C., Johnson T., Innovation and Perspectives in Solid Phase Synthesis 1994Ed. R.Epton Mayflower Worldwide. p551 - 554 554. Chain Association during Solid Phase Peptide Synthesis: Support, linker and spacer effects.

Byfield P., Bolgiano B., Hyde C., Martin D., Tuddenham E., Innovation and Perspectives in Solid Phase Synthesis and Combinatorial Libraries. 1996. Ed. R. Epton. Mayflower Scientific. p333 - 334.. Solution Structure of the Gla Domain of Clotting Factor VII by Circular Dichroism; Correlation with Inhibitory Properties.

This page last modified 14 May, 2008 by Richard Passey