The Biacore T100 enables you to determine
specificity, affinity, kinetic and thermodynamic parameters for
protein interactions with a variety of partners, from small molecules
to intact cells. You obtain unique information on one system, label
free and in real time!
The T100 can be used to:
Help elucidate disease mechanisms;
Select the best antibodies as research
tools, assay components or therapeutics;
Find potential drug or diagnostic targets;
Develop assays for interactions with low
molecular weight compounds;
Select protein therapeutic candidates according
to their thermodynamic properties and on/off rates;
Detect and characterise immune responses
during pre-clinical and clinical development and
Characterise protein therapeutics and implement
quality control methods.
All users must have attended a Biacore Basics
Training Course before they can use the instrument. These will be
run in-house every 4 - 6 months (maximum number of people per course
is 6) or can be booked off - site with Biacore direct. More in depth
courses on Kinetics are available from Biacore, please see their
web site for details.