Prof. Michael Häusser
- 020 7679 6756 / firstname.lastname@example.org
PhD Vacancy - closes 31/12/2009
Neurons are the basic cellular units of the
brain, and are connected via synapses to form neural networks. One
of the central questions in neuroscience is how particular tasks,
or "computations", are implemented by neural networks
to generate behaviour, and how patterns of activity are stored during
learning. In the past, the prevailing view has been that information
processing and storage in neural networks results mainly from properties
of synapses and connectivity of neurons within the network. As a
consequence, the contribution of single neurons to computation in
the brain has long been underestimated.
Kitamura K, Judkewitz B, Kano M, Denk
W, Häusser M. (2008). Targeted patch-clamp recordings and single-cell
electroporation of unlabeled neurons in vivo.
Nature Methods 5:61-7. [PubMed][DirectLink]
Rancz EA, Ishikawa T, Duguid I, Chadderton P, Mahon S, Häusser
M (2007). High-fidelity transmission of sensory information by single
cerebellar mossy fibre boutons.
Nature 450:1245-8. [PubMed][DirectLink]
Häusser M, Smith SL (2007). Controlling
neural circuits with light.
Nature 446:617-9. [PubMed][DirectLink]
Davie JT, Kole MH, Letzkus JJ, Rancz
EA, Spruston N, Stuart GJ, Häusser M (2006). Dendritic patch-clamp
Nature Protocols 1:1235-47. [PubMed][DirectLink]
Sjöström PJ, Häusser M.
(2006). A cooperative switch determines the sign of synaptic plasticity
in distal dendrites of neocortical pyramidal neurons.
Neuron 51(2):227-38. [PubMed][DirectLink]
London M, Häusser M (2005). Dendritic
computation. Annual Review of Neuroscience 28:503-32. [PubMed][DirectLink]