Prof. John Garthwaite
- 020 7679 6694 / john.garthwaite@ucl.ac.uk

Neural Signalling

Lab summary

Our interest is in understanding how cells in the brain carry out their main task, which is to communicate with one another and store information. We also aim to understand how abnormalities in communication can arise, because these are important in brain disorders such as epilepsy and chronic pain, as well as for the injury and death of brain cells that occurs acutely in conditions such as stroke, or more chronically in Alzheimer's and Parkinson's and other diseases.

More...

Selected publications

Garthwaite, J. (2005) Dynamics of cellular NO-cGMP signalling. Front. Biosci. 10: 1868-1880.

Riddall, D., Leach, M.J. and Garthwaite J. (2005) A novel drug binding site on voltage-gated sodium channels in rat brain. Mol. Pharmacol. Epub October 11.

Garthwaite, G., Batchelor, A.M., Goodwin, D.A., Hewson, A.K., Leeming, K, Ahmed, Z., Cuzner, M.L. and Garthwaite, J. (2005) Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis. Eur. J. Neurosci. 21: 2127-2135.

More...

Academic Career

Funding

TBA