The Wolfson Institute for Biomedical Research
at the Cruciform Building

Previous Events and Seminars

How neurons help mice to navigate in the environment

The hippocampus and the medial entorhinal cortex are the brain structures known to be important for navigation, a crucial survival skill (e.g. during foraging for food). A newly discovered type of neuron in the medial entorhinal cortex - grid cells - fire in a remarkable triangular grid-like pattern that spans the whole environment of a navigating animal, even in absolute darkness and in the absence of other sensory cues. These cells were discovered in 2004, and in the past decade many of their key features linked to spatial behaviour have been revealed. However, very little is known about how these neurons process the information they get from the other cell types and convert it to their distinctive activity patterns. I will describe my work investigating how the processing performed by single cells can help the brain achieve such a complex function as spatial navigation.



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