A A A

News

Poster for Autophagy in London public lecture

Public lecture: The autophagy signaling network, c-­‐myc and pathology: don't mess with the cell cycle!

You are invited to a public lecture by Francesco Cecconi, an eminent scientist in the field of autophagy and neurodegeneration, on Thursday the 25th of April at 17:00, in the lecture theatre of 33 Queen Square, University College Hospital London, WC1N. The lecture will be followed by a general discussion with drinks and food. More...

Link to film: Brain Disease Research - Keeping You You

Video: Brain Disease Research - Keeping You You


Have you ever wondered how scientists research the brain? Have you wondered who digs through that beautiful mass of grey matter between our ears to understand how it works and why it stops working? Meet the Neurodegenerative Diseases Initiative. Funded by the Wellcome Trust and MRC, this team of scientists from around the globe investigates Alzheimer's, Parkinson's and Motor Neuron Diseases. The team is on the hunt for understanding and treatments for brain diseases. More...

Degenerating Brains public symposium - 13th March 2013

Video: Degenerating Brains public symposium


The "Degenerating Brains" public symposium was held on the 13th March 2013, as part of Brain Awareness Week. Around 250 people showed up to hear Professors John Hardy (UCL), Chris Shaw (KCL) and David Rubinsztein (Cambridge) discuss new discoveries in neurodegenerative diseases and how they might impact drug treatment. More...

Colour-enhanced image of a mitochondrion showing the internal membranes (cristae) and enzyme complexes. Credit Dr David Furness, Wellcome Images.

Mutations in VCP gene implicated in a number of neurodegenerative diseases

New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget’s Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS). More...

Poster for Degenerating brains: new research into Alzheimer's, Parkinson's and Motor Neuron Disease

Public lectures: new research into Alzheimer's, Parkinson's and Motor Neuron Disease

You are invited to an evening (13th March 2013) exploring the very latest in cutting edge research into neurodegenerative diseases. Supported by the Wellcome Trust, scientists investigating Alzheimer's, Parkinson's and Motor Neuron disease will explain how our understanding of these disorders is changing in the light of new discoveries in genetics and cell biology, and how these discoveries impact on developing new drugs for these diseases.

18.00 Welcome and introduction

18.10 Lectures commence

More...

Anthony Schapira

(Principal Investigator)

Tony Schapira


Prof Tony Schapira is the Head of the Department of Clinical Neuroscience at the UCL Institute of Neurology and Chairman of Clinical Neurosciences Specialties.

The primary area of research in the department is the investigation of the aetiology and pathogenesis of neurodegenerative disorders. Specifically the department has an interest in the genetics and biochemistry of Parkinson's disease, Huntington's disease and Friedreich's ataxia. The department has established an international reputation in this area and in the area of diseases of the mitochondrial respiratory chain and inborn errors of mitochondrial function. There are also extensive research programmes on the genetics and pathogenesis of dystonia, motor neurone disease and peripheral nerve disorders. A joint appointment with the Hammersmith Hospital has provided an additional research interest in neuropsychology. Facilities for research are extensive. There are general laboratories for biochemistry, molecular biology, tissue preparation etc, in addition to specialist laboratory space for tissue culture (4 hoods), molecular biology, radioactive work, fluorimetry, spectrophotometry, lipid chemistry and histochemistry. There are advanced facilities for image analysis including an electron microscope.

esearcherID


Contact details

Lab website


Link to Publications RSS button
Jump to: 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988 | 1987 | 1986 | 1985 | 1981 | 1980 | 1977 | NULL
Number of items: 541.

2013

Alvarez-Erviti, L and Seow, Y and Schapira, AH and Rodriguez-Oroz, MC and Obeso, JA and Cooper, JM (2013) Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease. Cell Death Dis , 4 e545 - ?. 10.1038/cddis.2013.73.

Batla, A and Stamelou, M and Mencacci, N and Schapira, AH and Bhatia, KP (2013) Ropinirole monotherapy induced severe reversible dyskinesias in Parkinson's disease. Mov Disord 10.1002/mds.25318.

Berg, D and Lang, AE and Postuma, RB and Maetzler, W and Deuschl, G and Gasser, T and Siderowf, A and Schapira, AH and Oertel, W and Obeso, JA and Olanow, CW and Poewe, W and Stern, M (2013) Changing the research criteria for the diagnosis of Parkinson's disease: obstacles and opportunities. Lancet Neurol , 12 (5) 514 - 524. 10.1016/S1474-4422(13)70047-4.

Chau, KY and Cooper, JM and Schapira, AH (2013) Pramipexole Reduces Phosphorylation of α-Synuclein at Serine-129. J Mol Neurosci 10.1007/s12031-013-0030-8.

Cleeter, MW and Chau, KY and Gluck, C and Mehta, A and Hughes, DA and Duchen, M and Wood, NW and Hardy, J and Mark Cooper, J and Schapira, AH (2013) Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage. Neurochem Int , 62 (1) 1 - 7. 10.1016/j.neuint.2012.10.010.

Desouza, R and Moro, E and Lang, A and Schapira, A (2013) Timing of deep brain stimulation in Parkinson's disease: A need for reappraisal? Ann Neurol 10.1002/ana.23890.

Duran, R and Mencacci, NE and Angeli, AV and Shoai, M and Deas, E and Houlden, H and Mehta, A and Hughes, D and Cox, TM and Deegan, P and Schapira, AH and Lees, AJ and Limousin, P and Jarman, PR and Bhatia, KP and Wood, NW and Hardy, J and Foltynie, T (2013) The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease. Mov Disord , 28 (2) 232 - 236. 10.1002/mds.25248.

Ferreira, JJ and Katzenschlager, R and Bloem, BR and Bonuccelli, U and Burn, D and Deuschl, G and Dietrichs, E and Fabbrini, G and Friedman, A and Kanovsky, P and Kostic, V and Nieuwboer, A and Odin, P and Poewe, W and Rascol, O and Sampaio, C and Schüpbach, M and Tolosa, E and Trenkwalder, C and Schapira, A and Berardelli, A and Oertel, WH (2013) Summary of the recommendations of the EFNS/MDS-ES review on therapeutic management of Parkinson's disease. Eur J Neurol , 20 (1) 5 - 15. 10.1111/j.1468-1331.2012.03866.x.

Holmans, P and Moskvina, V and Jones, L and Sharma, M and International Parkinson's Disease Genomics Consortium, and Vedernikov, A and Buchel, F and Sadd, M and Bras, JM and Bettella, F and Nicolaou, N and Simón-Sánchez, J and Mittag, F and Gibbs, JR and Schulte, C and Durr, A and Guerreiro, R and Hernandez, D and Brice, A and Stefánsson, H and Majamaa, K and Gasser, T and Heutink, P and Wood, NW and Martinez, M and Singleton, AB and Nalls, MA and Hardy, J and Morris, HR and Williams, NM (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet , 22 (5) 1039 - 1049. 10.1093/hmg/dds492.

Kilpatrick, BS and Eden, ER and Schapira, AH and Futter, CE and Patel, S (2013) Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals. J Cell Sci , 126 (Pt 1) 60 - 66. 10.1242/jcs.118836.

Klebe, S and Golmard, JL and Nalls, MA and Saad, M and Singleton, AB and Bras, JM and Hardy, J and Simon-Sanchez, J and Heutink, P and Kuhlenbäumer, G and Charfi, R and Klein, C and Hagenah, J and Gasser, T and Wurster, I and Lesage, S and Lorenz, D and Deuschl, G and Durif, F and Pollak, P and Damier, P and Tison, F and Durr, A and Amouyel, P and Lambert, JC and Tzourio, C and Maubaret, C and Charbonnier-Beaupel, F and Tahiri, K and Vidailhet, M and Martinez, M and Brice, A and Corvol, JC and French Parkinson's Disease Genetics Study Group and the International Parkinson's Disease Genomics Consortium (IPDGC), (2013) The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism. J Neurol Neurosurg Psychiatry , 84 (6) 666 - 673. 10.1136/jnnp-2012-304475.

McNeill, A and Roberti, G and Lascaratos, G and Hughes, D and Mehta, A and Garway-Heath, DF and Schapira, AH (2013) Retinal thinning in Gaucher disease patients and carriers: Results of a pilot study. Mol Genet Metab 10.1016/j.ymgme.2013.04.001.

Mullin, S and Schapira, A (2013) Α-synuclein and mitochondrial dysfunction in Parkinson's disease. Mol Neurobiol , 47 (2) 587 - 597. 10.1007/s12035-013-8394-x.

Osellame, LD and Rahim, AA and Hargreaves, IP and Gegg, ME and Richard-Londt, A and Brandner, S and Waddington, SN and Schapira, AHV and Duchen, MR (2013) Mitochondria and quality control defects in a mouse model of Gaucher disease - links to Parkinson’s Disease. Cell Metabolism (In press).

Proukakis, C and Dudzik, CG and Brier, T and MacKay, DS and Cooper, JM and Millhauser, GL and Houlden, H and Schapira, AH (2013) A novel α-synuclein missense mutation in Parkinson disease. Neurology , 80 (11) 1062 - 1064. 10.1212/WNL.0b013e31828727ba.

Proukakis, C and Houlden, H and Schapira, AH (2013) Somatic alpha-synuclein mutations in Parkinson's disease: Hypothesis and preliminary data. Mov Disord 10.1002/mds.25502.

Ray Chaudhuri, K and Rojo, JM and Schapira, AH and Brooks, DJ and Stocchi, F and Odin, P and Antonini, A and Brown, RJ and Martinez-Martin, P (2013) A proposal for a comprehensive grading of Parkinson's disease severity combining motor and non-motor assessments: meeting an unmet need. PLoS One , 8 (2) , Article e57221 . 10.1371/journal.pone.0057221.
An open access publication. A version is also available from UCL Discovery.
file

Sarkozy, A and Hicks, D and Hudson, J and Laval, SH and Barresi, R and Hilton-Jones, D and Deschauer, M and Harris, E and Rufibach, L and Hwang, E and Bashir, R and Walter, MC and Krause, S and van den Bergh, P and Illa, I and Pénisson-Besnier, I and De Waele, L and Turnbull, D and Guglieri, M and Schrank, B and Schoser, B and Seeger, J and Schreiber, H and Gläser, D and Eagle, M and Bailey, G and Walters, R and Longman, C and Norwood, F and Winer, J and Muntoni, F and Hanna, M and Roberts, M and Bindoff, LA and Brierley, C and Cooper, RG and Cottrell, DA and Davies, NP and Gibson, A and Gorman, GS and Hammans, S and Jackson, AP and Khan, A and Lane, R and McConville, J and McEntagart, M and Al-Memar, A and Nixon, J and Panicker, J and Parton, M and Petty, R and Price, CJ and Rakowicz, W and Ray, P and Schapira, AH and Swingler, R and Turner, C and Wagner, KR and Maddison, P and Shaw, PJ and Straub, V and Bushby, K and Lochmüller, H (2013) ANO5 Gene Analysis in a Large Cohort of Patients with Anoctaminopathy: Confirmation of Male Prevalence and High Occurrence of the Common Exon 5 Gene Mutation. Hum Mutat 10.1002/humu.22342.

Schapira, AH and Barone, P and Hauser, RA and Mizuno, Y and Rascol, O and Busse, M and Debieuvre, C and Fraessdorf, M and Poewe, W (2013) Success rate, efficacy, and safety/tolerability of overnight switching from immediate- to extended-release pramipexole in advanced Parkinson's disease. Eur J Neurol , 20 (1) 180 - 187. 10.1111/j.1468-1331.2012.03822.x.

Schapira, AH and Barone, P and Hauser, RA and Mizuno, Y and Rascol, O and Busse, M and Debieuvre, C and Fraessdorf, M and Poewe, W and Pramipexole ER Studies Group, (2013) Patient-reported convenience of once-daily versus three-times-daily dosing during long-term studies of pramipexole in early and advanced Parkinson's disease. Eur J Neurol , 20 (1) 50 - 56. 10.1111/j.1468-1331.2012.03712.x.

Schapira, AH and Gegg, ME (2013) Glucocerebrosidase in the pathogenesis and treatment of Parkinson disease. Proc Natl Acad Sci U S A , 110 (9) 3214 - 3215. 10.1073/pnas.1300822110.

Schapira, AH and Stocchi, F and Borgohain, R and Onofrj, M and Bhatt, M and Lorenzana, P and Lucini, V and Giuliani, R and Anand, R and Study 017 Investigators, (2013) Long-term efficacy and safety of safinamide as add-on therapy in early Parkinson's disease. Eur J Neurol , 20 (2) 271 - 280. 10.1111/j.1468-1331.2012.03840.x.

2012

Cnop, M and Igoillo-Esteve, M and Rai, M and Begu, A and Serroukh, Y and Depondt, C and Musuaya, AE and Marhfour, I and Ladrière, L and Moles Lopez, X and Lefkaditis, D and Moore, F and Brion, JP and Cooper, JM and Schapira, AH and Clark, A and Koeppen, AH and Marchetti, P and Pandolfo, M and Eizirik, DL and Féry, F (2012) Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes. Ann Neurol , 72 (6) 971 - 982. 10.1002/ana.23698.

Devine, MJ and Kaganovich, A and Ryten, M and Mamais, A and Trabzuni, D and Manzoni, C and McGoldrick, P and Chan, D and Dillman, A and Zerle, J and Horan, S and Taanman, JW and Hardy, J and Marti-Masso, JF and Healy, D and Schapira, AH and Wolozin, B and Bandopadhyay, R and Cookson, MR and van der Brug, MP and Lewis, PA (2012) Correction: Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue. PLOS ONE , 7 (1) , Article e22489. 10.1371/annotation/c12e4f9e-5aae-424b-a69f-fddf16976dc5.
An open access publication. A version is also available from UCL Discovery.
file

Duran, R and McNeill, A and Mehta, A and Hughes, D and Cox, T and Deegan, P and Schapira, AH and Hardy, J (2012) Novel pathogenic mutations in the glucocerebrosidase locus. Mol Genet Metab , 106 (4) 495 - 497. 10.1016/j.ymgme.2012.05.006.
An open access publication

Gardiner, AR and Bhatia, KP and Stamelou, M and Dale, RC and Kurian, MA and Schneider, SA and Wali, GM and Counihan, T and Schapira, AH and Spacey, SD and Valente, EM and Silveira-Moriyama, L and Teive, HA and Raskin, S and Sander, JW and Lees, A and Warner, T and Kullmann, DM and Wood, NW and Hanna, M and Houlden, H (2012) PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. Neurology , 79 (21) 2115 - 2121. 10.1212/WNL.0b013e3182752c5a.

Gegg, ME and Burke, D and Heales, SJ and Cooper, JM and Hardy, J and Wood, NW and Schapira, AH (2012) Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains. Ann Neurol , 72 (3) 455 - 463. 10.1002/ana.23614.

Keller, MF and Saad, M and Bras, J and Bettella, F and Nicolaou, N and Simón-Sánchez, J and Mittag, F and Büchel, F and Sharma, M and Gibbs, JR and Schulte, C and Moskvina, V and Durr, A and Holmans, P and Kilarski, LL and Guerreiro, R and Hernandez, DG and Brice, A and Ylikotila, P and Stefánsson, H and Majamaa, K and Morris, HR and Williams, N and Gasser, T and Heutink, P and Wood, NW and Hardy, J and Martinez, M and Singleton, AB and Nalls, MA and International Parkinson's Disease Genomics Consortium (IPDGC), and Wellcome Trust Case Control Consortium 2 (WTCCC2), (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet , 21 (22) 4996 - 5009. 10.1093/hmg/dds335.

Klionsky, DJ and Abdalla, FC and Abeliovich, H and Abraham, RT and Acevedo-Arozena, A and Adeli, K and Agholme, L and Agnello, M and Agostinis, P and Aguirre-Ghiso, JA and Ahn, HJ and Ait-Mohamed, O and Ait-Si-Ali, S and Akematsu, T and Akira, S and Al-Younes, HM and Al-Zeer, MA and Albert, ML and Albin, RL and Alegre-Abarrategui, J and Aleo, MF and Alirezaei, M and Almasan, A and Almonte-Becerril, M and Amano, A and Amaravadi, R and Amarnath, S and Amer, AO and Andrieu-Abadie, N and Anantharam, V and Ann, DK and Anoopkumar-Dukie, S and Aoki, H and Apostolova, N and Arancia, G and Aris, JP and Asanuma, K and Asare, NY and Ashida, H and Askanas, V and Askew, DS and Auberger, P and Baba, M and Backues, SK and Baehrecke, EH and Bahr, BA and Bai, XY and Bailly, Y and Baiocchi, R and Baldini, G and Balduini, W and Ballabio, A and Bamber, BA and Bampton, ET and Bánhegyi, G and Bartholomew, CR and Bassham, DC and Bast, RC and Batoko, H and Bay, BH and Beau, I and Béchet, DM and Begley, TJ and Behl, C and Behrends, C and Bekri, S and Bellaire, B and Bendall, LJ and Benetti, L and Berliocchi, L and Bernardi, H and Bernassola, F and Besteiro, S and Bhatia-Kissova, I and Bi, X and Biard-Piechaczyk, M and Blum, JS and Boise, LH and Bonaldo, P and Boone, DL and Bornhauser, BC and Bortoluci, KR and Bossis, I and Bost, F and Bourquin, JP and Boya, P and Boyer-Guittaut, M and Bozhkov, PV and Brady, NR and Brancolini, C and Brech, A and Brenman, JE and Brennand, A and Bresnick, EH and Brest, P and Bridges, D and Bristol, ML and Brookes, PS and Brown, EJ and Brumell, JH and Brunetti-Pierri, N and Brunk, UT and Bulman, DE and Bultman, SJ and Bultynck, G and Burbulla, LF and Bursch, W and Butchar, JP and Buzgariu, W and Bydlowski, SP and Cadwell, K and Cahová, M and Cai, D and Cai, J and Cai, Q and Calabretta, B and Calvo-Garrido, J and Camougrand, N and Campanella, M and Campos-Salinas, J and Candi, E and Cao, L and Caplan, AB and Carding, SR and Cardoso, SM and Carew, JS and Carlin, CR and Carmignac, V and Carneiro, LA and Carra, S and Caruso, RA and Casari, G and Casas, C and Castino, R and Cebollero, E and Cecconi, F and Celli, J and Chaachouay, H and Chae, HJ and Chai, CY and Chan, DC and Chan, EY and Chang, RC and Che, CM and Chen, CC and Chen, GC and Chen, GQ and Chen, M and Chen, Q and Chen, SS and Chen, W and Chen, X and Chen, X and Chen, X and Chen, YG and Chen, Y and Chen, Y and Chen, YJ and Chen, Z and Cheng, A and Cheng, CH and Cheng, Y and Cheong, H and Cheong, JH and Cherry, S and Chess-Williams, R and Cheung, ZH and Chevet, E and Chiang, HL and Chiarelli, R and Chiba, T and Chin, LS and Chiou, SH and Chisari, FV and Cho, CH and Cho, DH and Choi, AM and Choi, D and Choi, KS and Choi, ME and Chouaib, S and Choubey, D and Choubey, V and Chu, CT and Chuang, TH and Chueh, SH and Chun, T and Chwae, YJ and Chye, ML and Ciarcia, R and Ciriolo, MR and Clague, MJ and Clark, RS and Clarke, PG and Clarke, R and Codogno, P and Coller, HA and Colombo, MI and Comincini, S and Condello, M and Condorelli, F and Cookson, MR and Coombs, GH and Coppens, I and Corbalan, R and Cossart, P and Costelli, P and Costes, S and Coto-Montes, A and Couve, E and Coxon, FP and Cregg, JM and Crespo, JL and Cronjé, MJ and Cuervo, AM and Cullen, JJ and Czaja, MJ and D'Amelio, M and Darfeuille-Michaud, A and Davids, LM and Davies, FE and De Felici, M and de Groot, JF and de Haan, CA and De Martino, L and De Milito, A and De Tata, V and Debnath, J and Degterev, A and Dehay, B and Delbridge, LM and Demarchi, F and Deng, YZ and Dengjel, J and Dent, P and Denton, D and Deretic, V and Desai, SD and Devenish, RJ and Di Gioacchino, M and Di Paolo, G and Di Pietro, C and Díaz-Araya, G and Díaz-Laviada, I and Diaz-Meco, MT and Diaz-Nido, J and Dikic, I and Dinesh-Kumar, SP and Ding, WX and Distelhorst, CW and Diwan, A and Djavaheri-Mergny, M and Dokudovskaya, S and Dong, Z and Dorsey, FC and Dosenko, V and Dowling, JJ and Doxsey, S and Dreux, M and Drew, ME and Duan, Q and Duchosal, MA and Duff, K and Dugail, I and Durbeej, M and Duszenko, M and Edelstein, CL and Edinger, AL and Egea, G and Eichinger, L and Eissa, NT and Ekmekcioglu, S and El-Deiry, WS and Elazar, Z and Elgendy, M and Ellerby, LM and Eng, KE and Engelbrecht, AM and Engelender, S and Erenpreisa, J and Escalante, R and Esclatine, A and Eskelinen, EL and Espert, L and Espina, V and Fan, H and Fan, J and Fan, QW and Fan, Z and Fang, S and Fang, Y and Fanto, M and Fanzani, A and Farkas, T and Farré, JC and Faure, M and Fechheimer, M and Feng, CG and Feng, J and Feng, Q and Feng, Y and Fésüs, L and Feuer, R and Figueiredo-Pereira, ME and Fimia, GM and Fingar, DC and Finkbeiner, S and Finkel, T and Finley, KD and Fiorito, F and Fisher, EA and Fisher, PB and Flajolet, M and Florez-McClure, ML and Florio, S and Fon, EA and Fornai, F and Fortunato, F and Fotedar, R and Fowler, DH and Fox, HS and Franco, R and Frankel, LB and Fransen, M and Fuentes, JM and Fueyo, J and Fujii, J and Fujisaki, K and Fujita, E and Fukuda, M and Furukawa, RH and Gaestel, M and Gailly, P and Gajewska, M and Galliot, B and Galy, V and Ganesh, S and Ganetzky, B and Ganley, IG and Gao, FB and Gao, GF and Gao, J and Garcia, L and Garcia-Manero, G and Garcia-Marcos, M and Garmyn, M and Gartel, AL and Gatti, E and Gautel, M and Gawriluk, TR and Gegg, ME and Geng, J and Germain, M and Gestwicki, JE and Gewirtz, DA and Ghavami, S and Ghosh, P and Giammarioli, AM and Giatromanolaki, AN and Gibson, SB and Gilkerson, RW and Ginger, ML and Ginsberg, HN and Golab, J and Goligorsky, MS and Golstein, P and Gomez-Manzano, C and Goncu, E and Gongora, C and Gonzalez, CD and Gonzalez, R and González-Estévez, C and González-Polo, RA and Gonzalez-Rey, E and Gorbunov, NV and Gorski, S and Goruppi, S and Gottlieb, RA and Gozuacik, D and Granato, GE and Grant, GD and Green, KN and Gregorc, A and Gros, F and Grose, C and Grunt, TW and Gual, P and Guan, JL and Guan, KL and Guichard, SM and Gukovskaya, AS and Gukovsky, I and Gunst, J and Gustafsson, AB and Halayko, AJ and Hale, AN and Halonen, SK and Hamasaki, M and Han, F and Han, T and Hancock, MK and Hansen, M and Harada, H and Harada, M and Hardt, SE and Harper, JW and Harris, AL and Harris, J and Harris, SD and Hashimoto, M and Haspel, JA and Hayashi, S and Hazelhurst, LA and He, C and He, YW and Hébert, MJ and Heidenreich, KA and Helfrich, MH and Helgason, GV and Henske, EP and Herman, B and Herman, PK and Hetz, C and Hilfiker, S and Hill, JA and Hocking, LJ and Hofman, P and Hofmann, TG and Höhfeld, J and Holyoake, TL and Hong, MH and Hood, DA and Hotamisligil, GS and Houwerzijl, EJ and Høyer-Hansen, M and Hu, B and Hu, CA and Hu, HM and Hua, Y and Huang, C and Huang, J and Huang, S and Huang, WP and Huber, TB and Huh, WK and Hung, TH and Hupp, TR and Hur, GM and Hurley, JB and Hussain, SN and Hussey, PJ and Hwang, JJ and Hwang, S and Ichihara, A and Ilkhanizadeh, S and Inoki, K and Into, T and Iovane, V and Iovanna, JL and Ip, NY and Isaka, Y and Ishida, H and Isidoro, C and Isobe, K and Iwasaki, A and Izquierdo, M and Izumi, Y and Jaakkola, PM and Jäättelä, M and Jackson, GR and Jackson, WT and Janji, B and Jendrach, M and Jeon, JH and Jeung, EB and Jiang, H and Jiang, H and Jiang, JX and Jiang, M and Jiang, Q and Jiang, X and Jiang, X and Jiménez, A and Jin, M and Jin, S and Joe, CO and Johansen, T and Johnson, DE and Johnson, GV and Jones, NL and Joseph, B and Joseph, SK and Joubert, AM and Juhász, G and Juillerat-Jeanneret, L and Jung, CH and Jung, YK and Kaarniranta, K and Kaasik, A and Kabuta, T and Kadowaki, M and Kagedal, K and Kamada, Y and Kaminskyy, VO and Kampinga, HH and Kanamori, H and Kang, C and Kang, KB and Kang, KI and Kang, R and Kang, YA and Kanki, T and Kanneganti, TD and Kanno, H and Kanthasamy, AG and Kanthasamy, A and Karantza, V and Kaushal, GP and Kaushik, S and Kawazoe, Y and Ke, PY and Kehrl, JH and Kelekar, A and Kerkhoff, C and Kessel, DH and Khalil, H and Kiel, JA and Kiger, AA and Kihara, A and Kim, DR and Kim, DH and Kim, DH and Kim, EK and Kim, HR and Kim, JS and Kim, JH and Kim, JC and Kim, JK and Kim, PK and Kim, SW and Kim, YS and Kim, Y and Kimchi, A and Kimmelman, AC and King, JS and Kinsella, TJ and Kirkin, V and Kirshenbaum, LA and Kitamoto, K and Kitazato, K and Klein, L and Klimecki, WT and Klucken, J and Knecht, E and Ko, BC and Koch, JC and Koga, H and Koh, JY and Koh, YH and Koike, M and Komatsu, M and Kominami, E and Kong, HJ and Kong, WJ and Korolchuk, VI and Kotake, Y and Koukourakis, MI and Kouri Flores, JB and Kovács, AL and Kraft, C and Krainc, D and Krämer, H and Kretz-Remy, C and Krichevsky, AM and Kroemer, G and Krüger, R and Krut, O and Ktistakis, NT and Kuan, CY and Kucharczyk, R and Kumar, A and Kumar, R and Kumar, S and Kundu, M and Kung, HJ and Kurz, T and Kwon, HJ and La Spada, AR and Lafont, F and Lamark, T and Landry, J and Lane, JD and Lapaquette, P and Laporte, JF and László, L and Lavandero, S and Lavoie, JN and Layfield, R and Lazo, PA and Le, W and Le Cam, L and Ledbetter, DJ and Lee, AJ and Lee, BW and Lee, GM and Lee, J and Lee, JH and Lee, M and Lee, MS and Lee, SH and Leeuwenburgh, C and Legembre, P and Legouis, R and Lehmann, M and Lei, HY and Lei, QY and Leib, DA and Leiro, J and Lemasters, JJ and Lemoine, A and Lesniak, MS and Lev, D and Levenson, VV and Levine, B and Levy, E and Li, F and Li, JL and Li, L and Li, S and Li, W and Li, XJ and Li, YB and Li, YP and Liang, C and Liang, Q and Liao, YF and Liberski, PP and Lieberman, A and Lim, HJ and Lim, KL and Lim, K and Lin, CF and Lin, FC and Lin, J and Lin, JD and Lin, K and Lin, WW and Lin, WC and Lin, YL and Linden, R and Lingor, P and Lippincott-Schwartz, J and Lisanti, MP and Liton, PB and Liu, B and Liu, CF and Liu, K and Liu, L and Liu, QA and Liu, W and Liu, YC and Liu, Y and Lockshin, RA and Lok, CN and Lonial, S and Loos, B and Lopez-Berestein, G and López-Otín, C and Lossi, L and Lotze, MT and Lőw, P and Lu, B and Lu, B and Lu, B and Lu, Z and Luciano, F and Lukacs, NW and Lund, AH and Lynch-Day, MA and Ma, Y and Macian, F and MacKeigan, JP and Macleod, KF and Madeo, F and Maiuri, L and Maiuri, MC and Malagoli, D and Malicdan, MC and Malorni, W and Man, N and Mandelkow, EM and Manon, S and Manov, I and Mao, K and Mao, X and Mao, Z and Marambaud, P and Marazziti, D and Marcel, YL and Marchbank, K and Marchetti, P and Marciniak, SJ and Marcondes, M and Mardi, M and Marfe, G and Mariño, G and Markaki, M and Marten, MR and Martin, SJ and Martinand-Mari, C and Martinet, W and Martinez-Vicente, M and Masini, M and Matarrese, P and Matsuo, S and Matteoni, R and Mayer, A and Mazure, NM and McConkey, DJ and McConnell, MJ and McDermott, C and McDonald, C and McInerney, GM and McKenna, SL and McLaughlin, B and McLean, PJ and McMaster, CR and McQuibban, GA and Meijer, AJ and Meisler, MH and Meléndez, A and Melia, TJ and Melino, G and Mena, MA and Menendez, JA and Menna-Barreto, RF and Menon, MB and Menzies, FM and Mercer, CA and Merighi, A and Merry, DE and Meschini, S and Meyer, CG and Meyer, TF and Miao, CY and Miao, JY and Michels, PA and Michiels, C and Mijaljica, D and Milojkovic, A and Minucci, S and Miracco, C and Miranti, CK and Mitroulis, I and Miyazawa, K and Mizushima, N and Mograbi, B and Mohseni, S and Molero, X and Mollereau, B and Mollinedo, F and Momoi, T and Monastyrska, I and Monick, MM and Monteiro, MJ and Moore, MN and Mora, R and Moreau, K and Moreira, PI and Moriyasu, Y and Moscat, J and Mostowy, S and Mottram, JC and Motyl, T and Moussa, CE and Müller, S and Muller, S and Münger, K and Münz, C and Murphy, LO and Murphy, ME and Musarò, A and Mysorekar, I and Nagata, E and Nagata, K and Nahimana, A and Nair, U and Nakagawa, T and Nakahira, K and Nakano, H and Nakatogawa, H and Nanjundan, M and Naqvi, NI and Narendra, DP and Narita, M and Navarro, M and Nawrocki, ST and Nazarko, TY and Nemchenko, A and Netea, MG and Neufeld, TP and Ney, PA and Nezis, IP and Nguyen, HP and Nie, D and Nishino, I and Nislow, C and Nixon, RA and Noda, T and Noegel, AA and Nogalska, A and Noguchi, S and Notterpek, L and Novak, I and Nozaki, T and Nukina, N and Nürnberger, T and Nyfeler, B and Obara, K and Oberley, TD and Oddo, S and Ogawa, M and Ohashi, T and Okamoto, K and Oleinick, NL and Oliver, FJ and Olsen, LJ and Olsson, S and Opota, O and Osborne, TF and Ostrander, GK and Otsu, K and Ou, JH and Ouimet, M and Overholtzer, M and Ozpolat, B and Paganetti, P and Pagnini, U and Pallet, N and Palmer, GE and Palumbo, C and Pan, T and Panaretakis, T and Pandey, UB and Papackova, Z and Papassideri, I and Paris, I and Park, J and Park, OK and Parys, JB and Parzych, KR and Patschan, S and Patterson, C and Pattingre, S and Pawelek, JM and Peng, J and Perlmutter, DH and Perrotta, I and Perry, G and Pervaiz, S and Peter, M and Peters, GJ and Petersen, M and Petrovski, G and Phang, JM and Piacentini, M and Pierre, P and Pierrefite-Carle, V and Pierron, G and Pinkas-Kramarski, R and Piras, A and Piri, N and Platanias, LC and Pöggeler, S and Poirot, M and Poletti, A and Poüs, C and Pozuelo-Rubio, M and Prætorius-Ibba, M and Prasad, A and Prescott, M and Priault, M and Produit-Zengaffinen, N and Progulske-Fox, A and Proikas-Cezanne, T and Przedborski, S and Przyklenk, K and Puertollano, R and Puyal, J and Qian, SB and Qin, L and Qin, ZH and Quaggin, SE and Raben, N and Rabinowich, H and Rabkin, SW and Rahman, I and Rami, A and Ramm, G and Randall, G and Randow, F and Rao, VA and Rathmell, JC and Ravikumar, B and Ray, SK and Reed, BH and Reed, JC and Reggiori, F and Régnier-Vigouroux, A and Reichert, AS and Reiners, JJ and Reiter, RJ and Ren, J and Revuelta, JL and Rhodes, CJ and Ritis, K and Rizzo, E and Robbins, J and Roberge, M and Roca, H and Roccheri, MC and Rocchi, S and Rodemann, HP and Rodríguez de Córdoba, S and Rohrer, B and Roninson, IB and Rosen, K and Rost-Roszkowska, MM and Rouis, M and Rouschop, KM and Rovetta, F and Rubin, BP and Rubinsztein, DC and Ruckdeschel, K and Rucker, EB and Rudich, A and Rudolf, E and Ruiz-Opazo, N and Russo, R and Rusten, TE and Ryan, KM and Ryter, SW and Sabatini, DM and Sadoshima, J and Saha, T and Saitoh, T and Sakagami, H and Sakai, Y and Salekdeh, GH and Salomoni, P and Salvaterra, PM and Salvesen, G and Salvioli, R and Sanchez, AM and Sánchez-Alcázar, JA and Sánchez-Prieto, R and Sandri, M and Sankar, U and Sansanwal, P and Santambrogio, L and Saran, S and Sarkar, S and Sarwal, M and Sasakawa, C and Sasnauskiene, A and Sass, M and Sato, K and Sato, M and Schapira, AH and Scharl, M and Schätzl, HM and Scheper, W and Schiaffino, S and Schneider, C and Schneider, ME and Schneider-Stock, R and Schoenlein, PV and Schorderet, DF and Schüller, C and Schwartz, GK and Scorrano, L and Sealy, L and Seglen, PO and Segura-Aguilar, J and Seiliez, I and Seleverstov, O and Sell, C and Seo, JB and Separovic, D and Setaluri, V and Setoguchi, T and Settembre, C and Shacka, JJ and Shanmugam, M and Shapiro, IM and Shaulian, E and Shaw, RJ and Shelhamer, JH and Shen, HM and Shen, WC and Sheng, ZH and Shi, Y and Shibuya, K and Shidoji, Y and Shieh, JJ and Shih, CM and Shimada, Y and Shimizu, S and Shintani, T and Shirihai, OS and Shore, GC and Sibirny, AA and Sidhu, SB and Sikorska, B and Silva-Zacarin, EC and Simmons, A and Simon, AK and Simon, HU and Simone, C and Simonsen, A and Sinclair, DA and Singh, R and Sinha, D and Sinicrope, FA and Sirko, A and Siu, PM and Sivridis, E and Skop, V and Skulachev, VP and Slack, RS and Smaili, SS and Smith, DR and Soengas, MS and Soldati, T and Song, X and Sood, AK and Soong, TW and Sotgia, F and Spector, SA and Spies, CD and Springer, W and Srinivasula, SM and Stefanis, L and Steffan, JS and Stendel, R and Stenmark, H and Stephanou, A and Stern, ST and Sternberg, C and Stork, B and Strålfors, P and Subauste, CS and Sui, X and Sulzer, D and Sun, J and Sun, SY and Sun, ZJ and Sung, JJ and Suzuki, K and Suzuki, T and Swanson, MS and Swanton, C and Sweeney, ST and Sy, LK and Szabadkai, G and Tabas, I and Taegtmeyer, H and Tafani, M and Takács-Vellai, K and Takano, Y and Takegawa, K and Takemura, G and Takeshita, F and Talbot, NJ and Tan, KS and Tanaka, K and Tanaka, K and Tang, D and Tang, D and Tanida, I and Tannous, BA and Tavernarakis, N and Taylor, GS and Taylor, GA and Taylor, JP and Terada, LS and Terman, A and Tettamanti, G and Thevissen, K and Thompson, CB and Thorburn, A and Thumm, M and Tian, F and Tian, Y and Tocchini-Valentini, G and Tolkovsky, AM and Tomino, Y and Tönges, L and Tooze, SA and Tournier, C and Tower, J and Towns, R and Trajkovic, V and Travassos, LH and Tsai, TF and Tschan, MP and Tsubata, T and Tsung, A and Turk, B and Turner, LS and Tyagi, SC and Uchiyama, Y and Ueno, T and Umekawa, M and Umemiya-Shirafuji, R and Unni, VK and Vaccaro, MI and Valente, EM and Van den Berghe, G and van der Klei, IJ and van Doorn, W and van Dyk, LF and van Egmond, M and van Grunsven, LA and Vandenabeele, P and Vandenberghe, WP and Vanhorebeek, I and Vaquero, EC and Velasco, G and Vellai, T and Vicencio, JM and Vierstra, RD and Vila, M and Vindis, C and Viola, G and Viscomi, MT and Voitsekhovskaja, OV and von Haefen, C and Votruba, M and Wada, K and Wade-Martins, R and Walker, CL and Walsh, CM and Walter, J and Wan, XB and Wang, A and Wang, C and Wang, D and Wang, F and Wang, F and Wang, G and Wang, H and Wang, HG and Wang, HD and Wang, J and Wang, K and Wang, M and Wang, RC and Wang, X and Wang, X and Wang, YJ and Wang, Y and Wang, Z and Wang, ZC and Wang, Z and Wansink, DG and Ward, DM and Watada, H and Waters, SL and Webster, P and Wei, L and Weihl, CC and Weiss, WA and Welford, SM and Wen, LP and Whitehouse, CA and Whitton, JL and Whitworth, AJ and Wileman, T and Wiley, JW and Wilkinson, S and Willbold, D and Williams, RL and Williamson, PR and Wouters, BG and Wu, C and Wu, DC and Wu, WK and Wyttenbach, A and Xavier, RJ and Xi, Z and Xia, P and Xiao, G and Xie, Z and Xie, Z and Xu, DZ and Xu, J and Xu, L and Xu, X and Yamamoto, A and Yamamoto, A and Yamashina, S and Yamashita, M and Yan, X and Yanagida, M and Yang, DS and Yang, E and Yang, JM and Yang, SY and Yang, W and Yang, WY and Yang, Z and Yao, MC and Yao, TP and Yeganeh, B and Yen, WL and Yin, JJ and Yin, XM and Yoo, OJ and Yoon, G and Yoon, SY and Yorimitsu, T and Yoshikawa, Y and Yoshimori, T and Yoshimoto, K and You, HJ and Youle, RJ and Younes, A and Yu, L and Yu, L and Yu, SW and Yu, WH and Yuan, ZM and Yue, Z and Yun, CH and Yuzaki, M and Zabirnyk, O and Silva-Zacarin, E and Zacks, D and Zacksenhaus, E and Zaffaroni, N and Zakeri, Z and Zeh, HJ and Zeitlin, SO and Zhang, H and Zhang, HL and Zhang, J and Zhang, JP and Zhang, L and Zhang, L and Zhang, MY and Zhang, XD and Zhao, M and Zhao, YF and Zhao, Y and Zhao, ZJ and Zheng, X and Zhivotovsky, B and Zhong, Q and Zhou, CZ and Zhu, C and Zhu, WG and Zhu, XF and Zhu, X and Zhu, Y and Zoladek, T and Zong, WX and Zorzano, A and Zschocke, J and Zuckerbraun, B (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy , 8 (4) 445 - 544.

Lascaratos, G and Garway-Heath, DF and Willoughby, CE and Chau, KY and Schapira, AH (2012) Mitochondrial dysfunction in glaucoma: understanding genetic influences. Mitochondrion , 12 (2) 202 - 212. 10.1016/j.mito.2011.11.004.

McNeill, A and Duran, R and Hughes, DA and Mehta, A and Schapira, AH (2012) A clinical and family history study of Parkinson's disease in heterozygous glucocerebrosidase mutation carriers. J Neurol Neurosurg Psychiatry , 83 (8) 853 - 854. 10.1136/jnnp-2012-302402.

McNeill, A and Duran, R and Proukakis, C and Bras, J and Hughes, D and Mehta, A and Hardy, J and Wood, NW and Schapira, AH (2012) Hyposmia and cognitive impairment in Gaucher disease patients and carriers. Mov Disord , 27 (4) 526 - 532. 10.1002/mds.24945.

Mittag, F and Büchel, F and Saad, M and Jahn, A and Schulte, C and Bochdanovits, Z and Simón-Sánchez, J and Nalls, MA and Keller, M and Hernandez, DG and Gibbs, JR and Lesage, S and Brice, A and Heutink, P and Martinez, M and Wood, NW and Hardy, J and Singleton, AB and Zell, A and Gasser, T and Sharma, M and International Parkinson’s Disease Genomics Consortium, (2012) Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities. Hum Mutat , 33 (12) 1708 - 1718. 10.1002/humu.22161.

Mizuno, Y and Yamamoto, M and Kuno, S and Hasegawa, K and Hattori, N and Kagimura, T and Sarashina, A and Rascol, O and Schapira, AH and Barone, P and Hauser, RA and Poewe, W and Pramipexole ER Study Group, (2012) Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and (L)-dopa-undertreated Parkinson disease: a double-blind, randomized trial. Clin Neuropharmacol , 35 (4) 174 - 181. 10.1097/WNF.0b013e31825f77b9.

Osellame, LD and Rahim, A and Gegg, ME and Waddington, S and Schapira, AHV and Duchen, MR (2012) Accumulation of damaged mitochondria in neuropathic Gaucher disease, the most prevalent risk factor for Parkinson's disease, is due to defective cellular degradation machinery. In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. (pp. S79 - S80).

Papkovskaia, TD and Chau, KY and Inesta-Vaquera, F and Papkovsky, DB and Healy, DG and Nishio, K and Staddon, J and Duchen, MR and Hardy, J and Schapira, AH and Cooper, JM (2012) G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization. Hum Mol Genet , 21 (19) 4201 - 4213. 10.1093/hmg/dds244.
An open access publication

Schapira, AH (2012) Mitochondrial diseases. Lancet , 379 (9828) 1825 - 1834. 10.1016/S0140-6736(11)61305-6.

Schapira, AH (2012) Targeting mitochondria for neuroprotection in Parkinson's disease. Antioxid Redox Signal , 16 (9) 965 - 973. 10.1089/ars.2011.4419.

Schapira, AH and Hillbom, M (2012) Advances in neurology 2011-12. Eur J Neurol , 19 (10) 1267 - 1275. 10.1111/j.1468-1331.2012.03870.x.

Schapira, AH and Tan, EK (2012) Optimizing treatment for Parkinson's disease. Eur J Neurol , 19 (12) 1483 - 1486. 10.1111/ene.12025.

Stocchi, F and Borgohain, R and Onofrj, M and Schapira, AH and Bhatt, M and Lucini, V and Giuliani, R and Anand, R and Study 015 Investigators, (2012) A randomized, double-blind, placebo-controlled trial of safinamide as add-on therapy in early Parkinson's disease patients. Mov Disord , 27 (1) 106 - 112. 10.1002/mds.23954.

Wray, S and Self, M and NINDS Parkinson's Disease iPSC Consortium, and NINDS Huntington's Disease iPSC Consortium, and NINDS ALS iPSC Consortium, and Lewis, PA and Taanman, JW and Ryan, NS and Mahoney, CJ and Liang, Y and Devine, MJ and Sheerin, UM and Houlden, H and Morris, HR and Healy, D and Marti-Masso, JF and Preza, E and Barker, S and Sutherland, M and Corriveau, RA and D'Andrea, M and Schapira, AH and Uitti, RJ and Guttman, M and Opala, G and Jasinska-Myga, B and Puschmann, A and Nilsson, C and Espay, AJ and Slawek, J and Gutmann, L and Boeve, BF and Boylan, K and Stoessl, AJ and Ross, OA and Maragakis, NJ and Van Gerpen, J and Gerstenhaber, M and Gwinn, K and Dawson, TM and Isacson, O and Marder, KS and Clark, LN and Przedborski, SE and Finkbeiner, S and Rothstein, JD and Wszolek, ZK and Rossor, MN and Hardy, J (2012) Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLOS One , 7 (8) , Article e43099. 10.1371/journal.pone.0043099.
An open access publication. A version is also available from UCL Discovery.
file

2011

Abramov, AY and Gegg, M and Grunewald, A and Wood, NW and Klein, C and Schapira, AHV (2011) Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease. PLOS ONE , 6 (10) , Article e25622. 10.1371/journal.pone.0025622.
An open access publication. A version is also available from UCL Discovery.
file

Alvarez-Erviti, L and Seow, Y and Schapira, AH and Gardiner, C and Sargent, IL and Wood, MJA and Cooper, JM (2011) Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. NEUROBIOL DIS , 42 (3) 360 - 367. 10.1016/j.nbd.2011.01.029.
An open access publication

Brainin, M and Berardelli, A and Boon, P and Gilhus, NE and Leys, D and Ludolph, A and Schapira, AHV and Skvortskova, V and EFNS Sci Comm, (2011) Comment from the EFNS Scientific Committee on the letter from Gunther Haag concerning Bendsten L et al. EFNS guideline on the treatment of tension-type headache - report of an EFNS task force. Eur J Neurol 2010; 17: 1318-1325. EUR J NEUROL , 18 (7) E83 - E84. 10.1111/j.1468-1331.2011.03382.x.

Devine, MJ and Kaganovich, A and Ryten, M and Mamais, A and Trabzuni, D and Manzoni, C and McGoldrick, P and Chan, D and Dillman, A and Zerle, J and Horan, S and Taanman, JW and Hardy, J and Marti-Masso, JF and Healy, D and Schapira, AH and Wolozin, B and Bandopadhyay, R and Cookson, MR and van der Brug, MP and Lewis, PA (2011) Pathogenic LRRK2 Mutations Do Not Alter Gene Expression in Cell Model Systems or Human Brain Tissue. PLOS ONE , 6 (7) , Article e22489. 10.1371/journal.pone.0022489.
An open access publication. A version is also available from UCL Discovery.
file

Devine, MJ and Ryten, M and Vodicka, P and Thomson, AJ and Burdon, T and Houlden, H and Cavaleri, F and Nagano, M and Drummond, NJ and Taanman, JW and Schapira, AH and Gwinn, K and Hardy, J and Lewis, PA and Kunath, T (2011) Parkinson's disease induced pluripotent stem cells with triplication of the alpha-synuclein locus. NAT COMMUN , 2 , Article 440. 10.1038/ncomms1453.
An open access publication

Gegg, ME and Schapira, AHV (2011) PINK1-parkin-dependent mitophagy involves ubiquitination of mitofusins 1 and 2 Implications for Parkinson disease pathogenesis. AUTOPHAGY , 7 (2) 243 - 245. 10.4161/auto.7.2.14332.

International Parkinson's Disease Genomics Consortium (IPDGC), and Wellcome Trust Case Control Consortium 2 (WTCCC2), (2011) A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet , 7 (6) e1002142 - ?. 10.1371/journal.pgen.1002142.

Meissner, WG and Frasier, M and Gasser, T and Goetz, CG and Lozano, A and Piccini, P and Obeso, JA and Rascol, O and Schapira, A and Voon, V and Weiner, DM and Tison, F and Bezard, E (2011) Priorities in Parkinson's disease research. Nat Rev Drug Discov , 10 (5) 377 - 393. 10.1038/nrd3430.

Poewe, W and Rascol, O and Barone, P and Hauser, RA and Mizuno, Y and Haaksma, M and Salin, L and Juhel, N and Schapira, AHV and Pramipexole ER Studies Grp, (2011) Extended-release pramipexole in early Parkinson disease A 33-week randomized controlled trial. NEUROLOGY , 77 (8) 759 - 766.

Schapira, AH (2011) Monoamine oxidase B inhibitors for the treatment of Parkinson's disease: a review of symptomatic and potential disease-modifying effects. CNS Drugs , 25 (12) 1061 - 1071. 10.2165/11596310-000000000-00000.

Schapira, AH (2011) Mitochondrial pathology in Parkinson's disease. Mt Sinai J Med , 78 (6) 872 - 881. 10.1002/msj.20303.

Schapira, AH (2011) Aetiopathogenesis of Parkinson's disease. J Neurol , 258 (Suppl 2) S307 - S310. 10.1007/s00415-011-6016-y.

Schapira, AH and Gegg, M (2011) Mitochondrial contribution to Parkinson's disease pathogenesis. Parkinsons Dis , 2011 159160 - ?. 10.4061/2011/159160.
An open access publication

Schapira, AH and Hillbom, M (2011) Publishing changes and information delivery in the clinical neurosciences. Eur J Neurol , 18 (12) 1365 - 1372. 10.1111/j.1468-1331.2011.03594.x.

Schapira, AH and Jenner, P (2011) Etiology and Pathogenesis of Parkinson's Disease. MOVEMENT DISORD , 26 (6) 1049 - 1055. 10.1002/mds.23732.

Schapira, AHV (2011) Challenges to the development of disease-modifying therapies in Parkinson's disease. EUR J NEUROL , 18 16 - 21. 10.1111/j.1468-1331.2010.03324.x.

Schapira, AHV (2011) The management of Parkinson's disease - what is new? EUR J NEUROL , 18 1 - 2. 10.1111/j.1468-1331.2010.03323.x.

Schapira, AHV and Barone, P and Hauser, RA and Mizuno, Y and Rascol, O and Busse, M and Salin, L and Juhel, N and Poewe, W and Pramipexole ER Studies Grp, (2011) Extended-release pramipexole in advanced Parkinson disease A randomized controlled trial. NEUROLOGY , 77 (8) 767 - 774.

Schapira, AHV and Schrag, A (2011) Parkinson disease clinical subtypes and their implications. NAT REV NEUROL , 7 (5) 247 - 248. 10.1038/nrneurol.2011.40.

Sivam, D and Rizos, A and Martin, A and Naidu, Y and Renton, T and Schapira, AHV and Martinez-Martin, P and Antonini, A and Falup-Pecurariu, C and Odin, P and Chaudhuri, KR (2011) Pain in Parkinson's disease: Observational study of 225 patients. In: MOVEMENT DISORDERS. (pp. S182 - S182).

Stocchi, F and Giorgi, L and Hunter, B and Schapira, AHV (2011) PREPARED: Comparison of Prolonged and Immediate Release Ropinirole in Advanced Parkinson's Disease. MOVEMENT DISORD , 26 (7) 1259 - 1265. 10.1002/mds.23498.

Tan, EK and Schapira, AH (2011) LRRK2 as a therapeutic target in Parkinson's disease. EUR J NEUROL , 18 (4) 545 - 546. 10.1111/j.1468-1331.2010.03305.x.

Tan, EK and Schapira, AH (2011) New LRRK2 variants identified in Parkinson's disease. EUR J NEUROL , 18 (3) 369 - 370. 10.1111/j.1468-1331.2010.03163.x.

2010

Schapira, AH and Fahn, S and Lang, AET (Eds). (2010) Movement Disorders 4: Blue Book Neurology Series. (Vol.34). Elsevier Health Sciences

Alvarez-Erviti, L and Rodriguez-Oroz, MC and Cooper, JM and Caballero, C and Ferrer, I and Obeso, JA and Schapira, AHV (2010) Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains. ARCH NEUROL-CHICAGO , 67 (12) 1464 - 1472. 10.1001/archneuro1.2010.198.

Chau, KY and Cooper, JM and Schapira, AHV (2010) Rasagiline protects against alpha-synuclein induced sensitivity to oxidative stress in dopaminergic cells. NEUROCHEM INT , 57 (5) 525 - 529. 10.1016/j.neuint.2010.06.017.

Chaudhuri, KR and Prieto-Jurcynska, C and Naidu, Y and Mitra, T and Frades-Payo, B and Tluk, S and Ruessmann, A and Odin, P and Macphee, G and Stocchi, F and Ondo, W and Sethi, K and Schapira, AHV and Martinez-Martin, P (2010) The Nondeclaration of Nonmotor Symptoms of Parkinson's Disease to Health Care Professionals: An International Study Using the Nonmotor Symptoms Questionnaire. MOVEMENT DISORD , 25 (6) 704 - 709. 10.1002/mds.22868.

Gegg, ME and Cooper, JM and Chau, KY and Rojo, M and Schapira, AHV and Taanman, JW (2010) Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. HUM MOL GENET , 19 (24) 4861 - 4870. 10.1093/hmg/ddq419.

Grunewald, A and Voges, L and Rakovic, A and Kasten, M and Kock, N and Schapira, AHV and Orolicki, S and Klein, C (2010) Impact of Mutations in Parkin on Mitochondrial Function and Morphology. In: NEUROLOGY. (pp. A261 - A261). LIPPINCOTT WILLIAMS & WILKINS

Grunewald, A and Voges, L and Rakovic, A and Kasten, M and Vandebona, H and Hemmelmann, C and Lohmann, K and Orolicki, S and Ramirez, A and Schapira, AHV and Pramstaller, PP and Sue, CM and Klein, C (2010) Mutant Parkin Impairs Mitochondrial Function and Morphology in Human Fibroblasts. PLOS ONE , 5 (9) , Article e12962. 10.1371/journal.pone.0012962.
An open access publication. A version is also available from UCL Discovery.
file

Hauser, RA and Schapira, AHV and Rascol, O and Barone, P and Mizuno, Y and Salin, L and Haaksma, M and Juhel, N and Poewe, W (2010) Randomized, Double-Blind, Multicenter Evaluation of Pramipexole Extended Release Once Daily in Early Parkinson's Disease. MOVEMENT DISORD , 25 (15) 2542 - 2549. 10.1002/mds.23317.

Kajihara, M and Montagnese, S and Khanna, P and Amodio, P and Schapira, AH and Dusheiko, GM and Morgan, MY (2010) Parkinsonism in patients with chronic hepatitis C treated with interferon-alpha2b: a report of two cases. Eur.J.Gastroenterol.Hepatol. , 22 (5) 628 - 631.

Kajihara, M and Montagnese, S and Khanna, P and Amodio, P and Schapira, AHV and Dusheiko, GM and Morgan, MY (2010) Parkinsonism in patients with chronic hepatitis C treated with interferon-alpha 2b: a report of two cases. EUR J GASTROEN HEPAT , 22 (5) 628 - 631. 10.1097/MEG.0b013e32833383e3.

Obeso, JA and Rodriguez-Oroz, MC and Goetz, CG and Marin, C and Kordower, JH and Rodriguez, M and Hirsch, EC and Farrer, M and Schapira, AHV and Halliday, G (2010) Missing pieces in the Parkinson's disease puzzle. NAT MED , 16 (6) 653 - 661.

Rajagopalan, B and Francis, JM and Cooke, F and Korlipara, LVP and Blamire, AM and Schapira, AHV and Madan, J and Neubauer, S and Cooper, JM (2010) Analysis of the Factors Influencing the Cardiac Phenotype in Friedreich's Ataxia. MOVEMENT DISORD , 25 (7) 846 - 852. 10.1002/mds.22864.

Rascol, O and Barone, P and Hauser, RA and Mizuno, Y and Poewe, W and Schapira, AHV and Salin, L and Sohr, M and Debieuvre, C and Pramipexole Switch Study Grp, (2010) Efficacy, Safety, and Tolerability of Overnight Switching from Immediate- to Once Daily Extended-Release Pramipexole in Early Parkinson's Disease. MOVEMENT DISORD , 25 (14) 2326 - 2332. 10.1002/mds.23262.

Schapira, A (2010) Parkinson's Disease in Daily Practice. John Wiley & Sons Inc

Schapira, AHV (2010) Safinamide in the treatment of Parkinson's disease. EXPERT OPIN PHARMACO , 11 (13) 2261 - 2268. 10.1517/14656566.2010.511612.

Schapira, AHV (2010) Complex I: Inhibitors, inhibition and neurodegeneration. EXP NEUROL , 224 (2) 331 - 335. 10.1016/j.expneurol.2010.03.028.

Schapira, AHV (2010) Movement disorders: advances in cause and treatment. LANCET NEUROL , 9 (1) 6 - 7.

Schapira, AHV (2010) Future Strategies for Neuroprotection in Parkinson's Disease. NEURODEGENER DIS , 7 (1-3) 210 - 212. 10.1159/000295666.

Schapira, AHV and Albrecht, S and Barone, P and Comella, CL and McDermott, MP and Mizuno, Y and Poewe, W and Rascol, O and Marek, K (2010) Rationale for Delayed-Start Study of Pramipexole in Parkinson's Disease: The PROUD Study. MOVEMENT DISORD , 25 (11) 1627 - 1632. 10.1002/mds.23143.

Schapira, AHV and Barone, P and Hauser, RA and Mizuno, Y and Rascol, O and Busse, M and Debieuvre, C and Kagimura, T and Sohr, M and Yoshikawa, K and Poewe, W and Pramipexole ER Studies Grp, (2010) Comparisons among responses to pramipexole extended-release as adjunctive treatment in Japanese and non-Japanese studies of advanced Parkinson's disease. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 374 - 374). WILEY-BLACKWELL

Schapira, AHV and Barone, P and Hauser, RA and Mizuno, Y and Rascol, O and Busse, M and Debieuvre, C and Sohr, M and Poewe, W and Pramipexole ER Studies Grp, (2010) Sustained off-time decrease in patients using pramipexole extended-release as adjunctive treatment in advanced Parkinson's disease. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 100 - 100). WILEY-BLACKWELL

Schapira, AHV and Barone, P and Hauser, RA and Mizuno, Y and Rascol, O and Busse, M and Salin, L and Sohr, M and Poewe, W and Pramipexole ER Studies Grp, (2010) Sustained efficacy and tolerability of pramipexole extended-release as adjunctive treatment in advanced Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S309 - S309). WILEY-LISS

Schapira, AHV and Fox, S and Hauser, R and Jankovic, J and Kulisevsky, J and Pahwa, R and Poewe, W and von Raison, F and Kenney, C and Musch, B (2010) SETTLE study design: A 24-week, double-blind, placebo-controlled study of the efficacy and safety of safinamide as add-on therapy to levodopa in patients with Parkinson's diseases Add-On Therapy to Levodopa in Patients with Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S308 - S309). WILEY-LISS

Schapira, AHV and Tolosa, E (2010) Molecular and clinical prodrome of Parkinson disease: implications for treatment. NAT REV NEUROL , 6 (6) 309 - 317. 10.1038/nrneurol.2010.52.

Tan, EK and Schapira, AH (2010) Summary of GIGYF2 studies in Parkinson's disease: the burden of proof. EUR J NEUROL , 17 (2) 175 - 176. 10.1111/j.1468-1331.2009.02834.x.

Turner, C and Schapira, AHV (2010) Mitochondrial matters of the brain: the role in Huntington's disease. J BIOENERG BIOMEMBR , 42 (3) 193 - 198. 10.1007/s10863-010-9290-y.

2009

Bhattacharyya, S and Schapira, AH and Mikhailidis, DP and Davar, J (2009) Drug-induced fibrotic valvular heart disease. LANCET , 374 (9689) 577 - 585.

Cano, SJ and Riazi, A and Schapira, AHV and Cooper, JM and Hobart, JC (2009) Friedreich's Ataxia Impact Scale: A New Measure Striving to Provide the Flexibility Required by Today's Studies. MOVEMENT DISORD , 24 (7) 984 - 992. 10.1002/mds.22420.

Chau, KY and Ching, HL and Schapira, AHV and Cooper, JM (2009) Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson's disease pathogenesis. J NEUROCHEM , 110 (3) 1005 - 1013. 10.1111/j.1471-4159.2009.06191.x.

Chau, KY and Korlipara, LVP and Cooper, JM and Schapira, AHV (2009) Protection against paraquat and A53T alpha-synuclein toxicity by cabergoline is partially mediated by dopamine receptors. J NEUROL SCI , 278 (1-2) 44 - 53. 10.1016/j.jns.2008.11.012.

Chaudhuri, KR and Martinez-Martin, P and Sherman, R and Naidu, Y and Odin, P and Sethi, K and Ondo, W and Stocchi, F and Schapira, AHV and PD Non Motor Grp, (2009) The Non Motor Staging of Parkinson's Disease: Results from an International Study. In: NEUROLOGY. (pp. A322 - A322). LIPPINCOTT WILLIAMS & WILKINS

Chaudhuri, KR and Schapira, AHV (2009) Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment. LANCET NEUROL , 8 (5) 464 - 474.

Gallagher, DA and Schapira, AHV (2009) Etiopathogenesis and Treatment of Parkinson's Disease. CURR TOP MED CHEM , 9 (10) 860 - 868.

Gegg, ME and Cooper, JM and Schapira, AHV and Taanman, JW (2009) Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells. PLOS ONE , 4 (3) , Article e4756. 10.1371/journal.pone.0004756.
An open access publication. A version is also available from UCL Discovery.
file

Grunewald, A and Gegg, ME and Taanman, JW and King, RH and Kock, N and Klein, C and Schapira, AHV (2009) Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology. EXP NEUROL , 219 (1) 266 - 273. 10.1016/j.expneurol.2009.05.027.

Martinez-Martin, P and Sherman, R and Naidu, Y and Richards, C and Odin, P and Stocchi, F and Macphee, G and Schapira, AHV and Chaudhuri, KR (2009) Non- motor staging of Parkinson's disease (PD) and early longitudinal follow up results from an international study. In: MOVEMENT DISORDERS. (pp. S385 - S385). WILEY-LISS

Naidu, Y and Martinez-Martin, P and Mitra, T and Tluk, S and Stocchi, F and Macphee, G and Odin, P and Schapira, AHV and Sethi, K and Chaudhuri, KR (2009) Non declaration of non motor symptoms (NMS) of PD: An international study using the NMSQuest. In: MOVEMENT DISORDERS. (pp. S386 - S386). WILEY-LISS

Nissinen, H and Kuoppamaki, M and Leinonen, M and Schapira, AH (2009) Early versus delayed initiation of entacapone in levodopa-treated patients with Parkinson's disease: a long-term, retrospective analysis. EUR J NEUROL , 16 (12) 1305 - 1311. 10.1111/j.1468-1331.2009.02726.x.

Obeso, JA and Schapira, AH (2009) Compensatory Mechanisms in Parkinson's Disease. MOVEMENT DISORD , 24 (1) 153 - 154. 10.1002/mds.22177.

Reddy, P and Naidu, Y and Suleyman, N and Tluk, S and Odin, P and Macphee, G and Stocchi, F and Schapira, AHV and Chaudhuri, KR (2009) Characterisation of Restless Legs like syndrome in Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S375 - S375). WILEY-LISS

Schapira, A and Hartmann, A and Agid, Y (2009) Parkinsonian Disorders in Clinical Practice. Wiley-Blackwell

Schapira, A and Hartmann, A and Agid, Y (2009) Parkinsonian Disorders in Clinical Practice. Whiley Blackwell

Schapira, AH and Agid, Y and Barone, P and Jenner, P and Lemke, MR and Poewe, W and Rascol, O and Reichmann, H and Tolosa, E (2009) Perspectives on recent advances in the understanding and treatment of Parkinson's disease. EUR J NEUROL , 16 (10) 1090 - 1099. 10.1111/j.1468-1331.2009.02793.x.

Schapira, AH and Olanow, CW (2009) Initiating Therapy in Parkinson's Disease Reply. ANN NEUROL , 65 (4) 481 - 481. 10.1002/ana.21690.

Schapira, AHV (2009) Disease modifying agents in Parkinson's disease? In: JOURNAL OF THE NEUROLOGICAL SCIENCES. (pp. S46 - S46). ELSEVIER SCIENCE BV

Schapira, AHV (2009) Etiology and Pathogenesis of Parkinson Disease. NEUROL CLIN , 27 (3) 583 - +. 10.1016/j.ncl.2009.04.004.

Schapira, AHV (2009) Molecular and clinical pathways to neuroprotection of dopaminergic drugs in Parkinson disease. NEUROLOGY , 72 S44 - S50.

Schapira, AHV (2009) Neurobiology and treatment of Parkinson's disease. TRENDS PHARMACOL SCI , 30 (1) 41 - 47. 10.1016/j.tips.2008.10.005.

Schapira, AHV and Emre, M and Jenner, P and Poewe, W (2009) Levodopa in the treatment of Parkinson's disease. EUR J NEUROL , 16 (9) 982 - 989. 10.1111/j.1468-1331.2009.02697.x.

Taanman, JW and Daras, M and Albrecht, J and Davie, CA and Mallam, EA and Muddle, JR and Weatherall, M and Warner, TT and Schapira, AHV and Ginsberg, L (2009) Characterization of a novel TYMP splice site mutation associated with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). NEUROMUSCULAR DISORD , 19 (2) 151 - 154. 10.1016/j.nmd.2008.11.002.

Taanman, JW and Rahman, S and Pagnamenta, AT and Morris, AAM and Bitner-Glindzicz, M and Wolf, NI and Leonard, JV and Clayton, PT and Schapira, AHV (2009) Analysis of Mutant DNA Polymerase gamma in Patients With Mitochondrial DNA Depletion. HUM MUTAT , 30 (2) 248 - 254. 10.1002/humu.20852.

Tolosa, E and Chaudhuri, KR and Schapira, A and Poewe, W (2009) Non-Motor Symptoms of Parkinson's Disease. Oxford Univ Pr

Warner, TT (2009) The genetics and pathogenesis of dystonia. In: Schapira, AHV and Lang, AE and Fahn, S, (eds.) Movement Disorders 4. (457 - 473). Elsevier: Philadelphia.

Webb, T and Mead, S and Beck, J and Uphill, J and Pal, S and Hampson, S and Wadsworth, JDF and Mena, ID and O'Malley, C and Wroe, S and Schapira, A and Brandner, S and Collinge, J (2009) Seven-year discordance in age at onset in monozygotic twins with inherited prion disease (P102L). NEUROPATH APPL NEURO , 35 (4) 427 - 432. 10.1111/j.1365-2990.2009.01012.x.

2008

Barone, P and Schapira, AHV and Debieuvre, CD and Massey, D (2008) Design of a randomized, placebo-controlled trial of pramipexole in patients with Parkinson's disease and depressive symptoms. In: MOVEMENT DISORDERS. (pp. S199 - S199). WILEY-LISS

Bet, L and Bareggi, SR and Pacei, F and Bondiolotti, G and Meola, G and Schapira, AHV (2008) Bimodal administration of entacapone in Parkinson's disease patients improves motor control. EUR J NEUROL , 15 (3) 268 - 273. 10.1111/j.1468-1331.2007.02043.x.

Cooper, JM and Korlipara, LVP and Hart, PE and Bradley, JL and Schapira, AHV (2008) Coenzyme Q(10) and vitamin E deficiency in Friedreich's ataxia: predictor of efficacy of vitamin E and coenzyme Q(10) therapy. EUR J NEUROL , 15 (12) 1371 - 1379. 10.1111/j.1468-1331.2008.02318.x.

DiFrancesco, JC and Cooper, JM and Lam, A and Hart, PE and Tremolizzo, L and Ferrarese, C and Schapira, AH (2008) MELAS mitochondrial DNA mutation A3243G reduces glutamate transport in cybrids cell lines. EXP NEUROL , 212 (1) 152 - 156. 10.1016/j.expneurol.2008.03.015.

Grosset, DG and Schapira, AH (2008) Timing the initiation of treatment in Parkinson's disease. J NEUROL NEUROSUR PS , 79 (6) 615 - 615. 10.1136/jnnp.2008.144741.

Healy, DG and Falchi, M and O'Sullivan, SS and Bonifati, V and Durr, A and Bressman, S and Brice, A and Aasly, J and Zabetian, CP and Goldwurm, S and Ferreira, JJ and Tolosa, E and Kay, DM and Klein, C and Williams, DR and Marras, C and Lang, AE and KWszolek, Z and Berciano, J and Schapira, AHV and Lynch, T and Bhatia, KP and Gasser, T and Lees, AJ and Wood, NW and Int LRRK2 Consortium, (2008) Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. LANCET NEUROL , 7 (7) 583 - 590. 10.1016/S1474-4422(08)70117-0.
An open access publication

Healy, DG and Wood, NW and Schapira, AH (2008) Test for LRRK2 mutations in patients with Parkinson's disease. Pract Neurol , 8 (6) 381 - 385. 10.1136/jnnp.2008.162420.

Martinez, C and Finnern, HW and Rietbrock, S and Eaton, S and Chaudhuri, KR and Schapira, AHV (2008) Patterns of treatment for restless legs syndrome in primary care in the united kingdom. CLIN THER , 30 (2) 405 - 418. 10.1016/j.clinthera.2008.02.001.

Olanow, CW and Kleburtz, K and Schapira, AHV (2008) Why Have We Failed to Achieve Neuroprotection in Parkinson's Disease? ANN NEUROL , 64 (6) S101 - S110. 10.1002/ana.21461.

Rohrer, JD and Schapira, AH (2008) Transient Horner's syndrome during lumbar epidural anaesthesia. EUR J NEUROL , 15 (5) 530 - 531. 10.1111/j.1468-1331.2008.02120.x.

Schapira, AH (2008) Progress in Parkinson's disease. EUR J NEUROL , 15 (1) 1 - 1. 10.1111/j.1468-1331.2007.02036.x.

Schapira, AH and Hsu, HH and Scrine, K and Gordon, MF and Marek, KL (2008) PROUD: The impact of early vs. delayed treatment with prampiexole on new onset Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S194 - S194). WILEY-LISS

Schapira, AH and Hsu, HH and Scrine, K and Gordon, MF and Marek, KL (2008) PROUD: The impact of early vs. delayed treatment with pramipexole on new onset Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S194 - S194). WILEY-LISS

Schapira, AHV (2008) Mitochondrial Dysfunction in Neurodegenerative Diseases. NEUROCHEM RES , 33 (12) 2502 - 2509. 10.1007/s11064-008-9855-x.

Schapira, AHV (2008) Controlling motor symptoms and fluctuations in adjunct therapy. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 418 - 418). BLACKWELL PUBLISHING

Schapira, AHV (2008) Rasagiline in neurodegeneration. EXP NEUROL , 212 (2) 255 - 257. 10.1016/j.expneurol.2008.05.002.

Schapira, AHV (2008) Progress in neuroprotection in Parkinson's disease. EUR J NEUROL , 15 5 - 13.

Schapira, AHV (2008) The scientific and clinical basis for future therapies in Parkinson's disease - Foreword. EUR J NEUROL , 15 V - V.

Schapira, AHV (2008) The clinical relevance of levodopa toxicity in the treatment of Parkinson's disease. MOVEMENT DISORD , 23 S515 - S520. 10.1002/mds.22146.

Schapira, AHV (2008) Mitochondria in the aetiology and pathogenesis of Parkinson's disease. LANCET NEUROL , 7 (1) 97 - 109.

Schapira, AHV and Borgohain, R and Stocchi, F and Lorenzana, P and Onofrj, M and Lucini, V and Giuliani, R and Rossetti, SM and Anand, R and Study Investigators, (2008) Long-term safety and efficacy of safinamide added to dopamine agonists in early Parkinson's disease (PD). In: NEUROLOGY. (pp. A424 - A424). LIPPINCOTT WILLIAMS & WILKINS

Schapira, AHV and Hsu, HH and Scrine, K and Gordon, MF and Marek, KL (2008) PROUD: the impact of early vs. delayed treatment with pramipexole on new onset Parkinson's disease. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 132 - 132). BLACKWELL PUBLISHING

Schapira, AHV and Olanow, CW (2008) Drug Selection and Timing of Initiation of Treatment in Early Parkinson's Disease. ANN NEUROL , 64 (6) S47 - S55. 10.1002/ana.21460.

Schapira, AHV and Stocchi, F and Hunter, B and Giorgi, L (2008) Adjunctive ropinirole 24-hour prolonged release compared with adjunctive ropinirole immediate release in patients with advanced PD: results from a per-protocol analysis of the PREPARED study. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 131 - 132). BLACKWELL PUBLISHING

Schapira, AHV and Stocchi, F and Hunter, B and Giorgi, L (2008) Comparison of adjunctive ropinirole 24-hour prolonged release and ropinirole immediate release in patients with advanced Parkinson's disease: A per-protocol analysis of the PREPARED study. In: MOVEMENT DISORDERS. (pp. S196 - S197). WILEY-LISS

Stocchi, F and Hunter, B and Giorgi, L and Schapira, AHV (2008) Adjunctive ropinirole 24-hour prolonged release compared with ropinirole immediate release in patients with advanced Parkinson's disease (PD): the PREPARED study. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 134 - 134). BLACKWELL PUBLISHING

Stocchi, F and Hunter, B and Giorgi, L and Schapira, AHV (2008) On evaluation of symptom control in patients with advanced PD receiving adjunctive ropinirole 24-hour prolonged release versus ropinirole immediate release: results from the PREPARED study. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 134 - 134). BLACKWELL PUBLISHING

Stocchi, F and Huter, B and Giorgi, L and Schapira, AHV (2008) Comparison of adjunctive ropinirole 24-hour prolonged release and ropinirole immediate release in patients with advanced Parkinson's disease: The PREPARED study. In: MOVEMENT DISORDERS. (pp. S215 - S216). WILEY-LISS

Tan, EK and Schapira, AH (2008) Hunting for genes in essential tremor. EUR J NEUROL , 15 (9) 889 - 890. 10.1111/j.1468-1331.2008.02226.x.

Tan, EK and Schapira, AH (2008) Uniting Chinese across Asia: The LRRK2 Gly2385Arg risk variant. EUR J NEUROL , 15 (3) 203 - 204. 10.1111/j.1468-1331.2007.02053.x.

Yamamoto, M and Schapira, AH (2008) Dopamine agonists in Parkinson's disease. Expert Rev Neurother , 8 (4) 671 - 677. 10.1586/14737175.8.4.671.

2007

Schapira, AHV and Byrne, E and Dimauro, S and Frackowiak, RSJ and Johnson, RT and Mizuno, Y and Samuels, MA and Silberstein, SD and Wszolek, ZK (Eds). (2007) Neurology and clinical neuroscience - a textbook of neurology. Elsevier: Philadelphia.

Anand, R and Onofrj, M and Schapira, AH and Rossetti, SM (2007) Safinamide potentiates the effects of DA-agonists in early stage Parkinson's disease (PD) patients. In: MOVEMENT DISORDERS. (pp. S244 - S244). WILEY-LISS

Barone, P and Goetz, CG and Houben, J and Juergen, K and Leentjens, AFG and Poewe, W and Rascol, OO and Reichmann, H and Schapira, AH and Tolosa, E (2007) PRODEST study: depressive symptoms in Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S183 - S183). WILEY-LISS

Barone, P and Goetz, CG and Houben, JJ and Koester, J and Leentjens, AF and Poewe, W and Rascol, O and Reichmann, H and Schapira, AH and Tolosa, E (2007) Prodest - Depressive symptoms in Parkinson's disease: Demographic data. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 61 - 61). BLACKWELL PUBLISHING

Barone, P and Goetz, CG and Houben, JJ and Koster, J and Leentjens, AFG and Powe, W and Rascol, O and Reichmann, H and Schapira, AH and Tolosa, E (2007) PRODEST - Depressive symptoms in Parkinson's disease: Pattern across scales. PARKINSONISM RELAT D , 13 S51 - S51.

Chaudhuri, KR and Martinez-Martin, P and Brown, RG and Sethi, K and Stocchi, F and Odin, P and Ondo, W and Abe, K and MacPhee, G and MacMahon, D and Barone, P and Rabey, M and Forbes, A and Breen, K and Tluk, S and Naidu, Y and Olanow, W and Williams, AJ and Thomas, S and Rye, D and Tsuboi, Y and Hand, A and Schapira, AHV (2007) The metric properties of a novel non-motor symptoms scale for Parkinson's disease: Results from an international pilot study. MOVEMENT DISORD , 22 (13) 1901 - 1911. 10.1002/mds.21596.

Chaudhuri, KR and Martinez-Martin, P and Schapira, AHV and Stocchi, F and Sethi, K and Odin, P and Brown, RG and Ondo, W and MacMahon, DG and MacPhee, G and Forbes, A and Naidu, Y and Clayton, L and Tluk, S and Bowron, A and Barone, P and Rabey, M and PDNMG, (2007) International validation of the first non-motor questionnaire (NMSQuest) and scale (NMSS) for Parkinson's disease. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 213 - 213). B M J PUBLISHING GROUP

Cooper, JM and Schapira, AHV (2007) Friedreich's ataxia: Coenzyme Q(10) and vitamin E therapy. MITOCHONDRION , 7 S127 - S135. 10.1016/j.mito.2007.04.001.

Giladi, N and Boroojerdi, B and Korczyn, AD and Burn, DJ and Clarke, CE and Schapira, AH and SP513 Investigators, (2007) Rotigotine transdermal patch in early Parkinson's disease: A randomized, double-blind, controlled study versus placebo and ropinirole. MOVEMENT DISORD , 22 (16) 2398 - 2404. 10.1002/mds.21741.

Ginsberg, L and Daras, M and Davie, C and Albrecht, J and Schapira, AHV and Weatherall, M and Taanman, JW (2007) A novel MNGIE mutation. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 238 - 238). BLACKWELL PUBLISHING

Ginsberg, L and Schapiro, AHV and Taanman, JM (2007) Relapsing neuropathy in an 18-year-old woman. LANCET NEUROL , 6 (2) 192 - 198.

Lynch, JM and Sisodiya, SM (2007) Genetics of epilepsy. In: Schapira, AHV, (ed.) Neurology and clinical neuroscience. (681 - 689). Mosby/Elsevier: Philadelphia.
An open access version is available from UCL Discovery
file

Martinez-Martin, P and Schapira, AHV and Stocchi, F and Sethi, K and Odin, P and MacPhee, G and Brown, RG and Naidu, Y and Clayton, L and Abe, K and Tsuboi, Y and MacMahon, D and Barone, P and Rabey, M and Bonuccelli, U and Forbes, A and Breen, K and Tluk, S and Olanow, CW and Thomas, S and Rye, D and Hand, A and Williams, AJ and Ondo, W and Chaudhuri, KR (2007) Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; Study using nonmotor symptoms questionnaire in 545 patients. MOVEMENT DISORD , 22 (11) 1623 - 1629. 10.1002/mds.21586.

Pienaar, I and Carr, J and Hattingh, S and Morten, K and Schallert, T and Schapira, AH and Daniels, W (2007) A proteomics and behavioral analysis of the interaction of statins with mitochondrial proteins in a rat model of Parkinson's disease. PARKINSONISM RELAT D , 13 S91 - S91.

Pienaar, I and Carr, J and Hattingh, S and Morten, K and Schallert, T and Schapira, AH and Daniels, W (2007) A proteomics and behavioral analysis of the interaction of statins with mitochondrial proteins in a rat model of Parkinson's disease. PARKINSONISM RELAT D , 13 S133 - S133.

Schapira, AH (2007) Mitochondria in the etiology of Parkinson's disease. Handb Clin Neurol , 83 479 - 491. 10.1016/S0072-9752(07)83022-3.

Schapira, AHV (2007) Ropinirole 24-hour extended release for Parkinson's disease. In: AKTUELLE NEUROLOGIE. (pp. S15 - S17). GEORG THIEME VERLAG KG

Schapira, AHV (2007) Treatment options in the modern management of Parkinson Disease. ARCH NEUROL-CHICAGO , 64 (8) 1083 - 1088.

Schapira, AHV (2007) Mitochondrial dysfunction in Parkinson's disease. CELL DEATH DIFFER , 14 (7) 1261 - 1266. 10.1038/sj.cdd.4402160.

Schapira, AHV (2007) Future directions in the treatment of Parkinson's disease. MOVEMENT DISORDERS , 22 S385 - S391. 10.1002/mds.21679.

Schapira, AHV (2007) Metabolic causes of ataxia. In: Brice, A and Pulst, SM, (eds.) Spinocerebellar degenerations: the ataxias and spastic paraplegias. (255 - 267). Butterworth-Heinemann Elsevier: Philadelphia.

Schapira, AHV (2007) Mitochondria in Movement Disorders. In: Jankovic, J and Tolosa, E, (eds.) Parkinson's Disease & Movement Disorders. (284 - 297). Lippincott Williams & Wilkins: Philadelphia.

Schapira, AHV (2007) Mitochondria in the etiology of Parkinson's disease. In: Koller, WC and Melamed, E, (eds.) Parkinson's disease and related disorders, part I. (481 - 491). Elsevier: Edinburgh.

Schapira, AHV and Chau, KY and Cooper, JM (2007) Cabergoline protects against paraquant and alpha-synuclein mutation toxicity. In: NEUROLOGY. (pp. A110 - A110). LIPPINCOTT WILLIAMS & WILKINS

Sharma, T and Stocchi, F and Schapira, AH and Borgohain, R and LoreDzana, P and Onoftj, M and Rossetti, S and De Santi, S and Anand, R and 015 Study Grp, (2007) Satinamide treatment improves cognition in Parkinson's disease. In: MOVEMENT DISORDERS. (pp. XII - XIII). WILEY-LISS

Simonson, W and Hauser, RA and Schapira, AHV (2007) Role of the pharmacist in the effective management of wearing-off in Parkinson's disease. ANN PHARMACOTHER , 41 (11) 1842 - 1849. 10.1345/aph.1K348.

Turner, C and Cooper, JM and Schapira, AHV (2007) Clinical correlates of mitochondrial function in Huntington's disease muscle. MOVEMENT DISORD , 22 (12) 1715 - 1721. 10.1002/mds.21540.

Warner, TT (2007) Dystonia. In: Schapira, AHV, (ed.) Neurology and Clinical Neurosciences. (443 - 454). Mosby Elsevier: Philadelphia.

2006

Cano, SJ and Hobart, JC and Hart, PE and Kolipara, LVP and Schapira, AHV and Cooper, JM (2006) International co-operative ataxia rating scale (ICARS): Suitable for clinical practice and treatment trials in Friedreich's ataxia? In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 133 - 133). B M J PUBLISHING GROUP

Cano, SJ and Riazi, A and Cooper, JM and Schapira, AHV and Hobart, JC (2006) The Friedreich's Ataxia impact scale (FAIS) meets the needs of today's clinical studies. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 133 - 133). B M J PUBLISHING GROUP

Chaudhuri, KR and Healy, DG and Schapira, AHV (2006) Non-motor symptoms of Parkinson's disease: diagnosis and management. LANCET NEUROL , 5 (3) 235 - 245.

Chaudhuri, KR and Martinez-Martin, P and Schapira, AHV and Sethi, K and Ondo, W and Stocchi, F and Odin, P and Brown, R (2006) International validation of the first united non motor symptoms scale for Parkinson's disease. Results from the first pilot NMSS study. In: NEUROLOGY. (pp. A124 - A124). LIPPINCOTT WILLIAMS & WILKINS

Chaudhuri, KR and Martinez-Martin, P and Schapira, AHV and Stocchi, F and Sethi, K and Odin, P and Brown, RG and Koller, W and Barone, P and MacPhee, G and Kelly, L and Rabey, M and MacMahon, D and Thomas, S and Ondo, W and Rye, D and Forbes, A and Tluk, S and Dhawan, V and Bowron, A and Williams, AJ and Olanow, CW (2006) International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: The NMSQuest study. MOVEMENT DISORD , 21 (7) 916 - 923. 10.1002/mds.20844.

Iravani, MM and Haddon, CO and Cooper, JM and Jenner, P and Schapira, AH (2006) Pramipexole protects against MPTP toxicity in non-human primates. J NEUROCHEM , 96 (5) 1315 - 1321. 10.1111/j.1471-4159.2005.03625.x.

Lodi, R and Tonon, C and Calabrese, V and Schapira, AHV (2006) Friedreich's ataxia: From disease mechanisms to therapeutic interventions. ANTIOXID REDOX SIGN , 8 (3-4) 438 - 443.

Naidu, Y and Schapira, AH and Martinez-Martin, P and Sethi, K and Odin, P and Stocchi, F and Ondo, W and Olanow, CW and Barone, P and MacMahon, D and MacPhee, G and Forbes, A and Rabey, M and Breen, K and Bowron, A and Tluk, S and Thomas, S and Abe, K and Williams, A and Rye, D and Chaudhuri, KR (2006) International validation study of the first comprehensive unified Nonmotor Symptoms Scale (NMSS) for Parkinson's disease (PD). In: MOVEMENT DISORDERS. (pp. S613 - S613). WILEY-LISS

Olanow, CW and Schapira, AHV and LeWitt, PA and Kieburtz, K and Sauer, D and Olivieri, G and Pohlmann, H and Hubble, J (2006) TCH346 as a neuroprotective drug in Parkinson"s disease: a double-blind, randomised, controlled trial. LANCET NEUROL , 5 (12) 1013 - 1020. 10.1016/S1474-4422(06)70602-0.

Riazi, A and Cano, SJ and Cooper, JM and Bradley, JL and Schapira, AHV and Hobart, JC (2006) Coordinating outcomes measurement in ataxia research: Do some widely used generic rating scales tick the boxes? MOVEMENT DISORD , 21 (9) 1396 - 1403. 10.1002/mds.20985.

Schapira, A.H.V. and Cleeter, M.W.J. and Muddle, J.R. and Workman, J.M. and Cooper, J.M. and King, R.H.M. (2006) Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons. Annals of Neurology , 60 (2) pp. 253-255. 10.1002/ana.20934.

Schapira, AH (2006) Scientific basis for neuroprotection in Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S14 - S14). WILEY-LISS

Schapira, AH (2006) The use of rasagiline in Parkinson's disease. journal of neural transmission , 71 1 - 5.

Schapira, AHV (2006) Parkinson's disease. In: Schapira, AHV, (ed.) Neurology and clinical neuroscience. (927 - 960). Mosby/Elsevier: Philadelphia.

Schapira, AHV (2006) Sudden onset of sleep and daytime drowsiness in Parkinson's disease. In: JOURNAL OF THE NEUROLOGICAL SCIENCES. (pp. 319 - 319). ELSEVIER SCIENCE BV

Schapira, AHV (2006) Restless Legs Syndrome - Preface. EUR J NEUROL , 13 1 - 1.

Schapira, AHV (2006) RLS patients: who are they? EUR J NEUROL , 13 2 - 7.

Schapira, AHV (2006) Improving the management of Parkinson's disease: New ropinirole data from EASE-PD in context. EUR J NEUROL , 13 317 - 317.

Schapira, AHV (2006) Non-motor symptoms. EUR J NEUROL , 13 316 - 317.

Schapira, AHV (2006) The importance of LRRK2 mutations in Parkinson disease. ARCH NEUROL-CHICAGO , 63 (9) 1225 - 1228.

Schapira, AHV (2006) Mitochondrial disease. LANCET , 368 (9529) 70 - 82.

Schapira, AHV (2006) Mitochondria in neurodegeneratives diseases. In: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. (pp. S82 - S83). CAMBRIDGE UNIV PRESS

Schapira, AHV (2006) Etiology of Parkinson's disease. NEUROLOGY , 66 (10) S10 - S23.

Schapira, AHV (2006) The use of rasagiline in Parkinson's disease. J NEURAL TRANSM-SUPP (71) 157 - 161.

Schapira, AHV and Bezard, E and Brotchie, J and Calon, F and Collingridge, GL and Ferger, B and Hengerer, B and Hirsch, E and Jenner, P and Le Novere, N and Obeso, JA and Schwarzschild, MA and Spampinato, U and Davidai, G (2006) Novel pharmacological targets for the treatment of Parkinson's disease. NAT REV DRUG DISCOV , 5 (10) 845 - 854. 10.1038/nrd2087.

Schapira, AHV and Cleeter, MWJ and Muddle, JR and Workman, JM and Cooper, JM and King, RHM (2006) Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons. ANN NEUROL , 60 (2) 253 - 255. 10.1002/ana.20934.

Schapira, AHV and Muddle, JR and Workman, JM and Cleeter, MWJ and Cooper, MJ and King, RHM (2006) Systemic proteasomal inhibition causes loss of nigral TH positive neurons. In: NEUROLOGY. (pp. A146 - A146). LIPPINCOTT WILLIAMS & WILKINS

Schapira, AHV and Obeso, J (2006) Timing of treatment initiation in Parkinson's disease: A need for reappraisal? ANN NEUROL , 59 (3) 559 - 562.

Schapira, AHV and Obeso, JA (2006) Treatment should not be initiated too soon in Parkinson's disease - Reply. ANN NEUROL , 59 (3) 564 - 565.

Stacey, M and Hauser, R and Oertel, W and Schapira, AH and Sethi, K and Stocchi, F and Tolosa, E (2006) End of dose wearing off in Parkinson's disease; A 9-question survey assessment. Clinical Pharmacology , 29 (6) 312 - 321.

Stacy, M and Hauser, R and Oertel, W and Schapira, A and Sethi, K and Stocchi, F and Tolosa, E (2006) End-of-dose wearing off in Parkinson disease: a 9-question survey assessment. Clin Neuropharmacol , 29 (6) 312 - 321. 10.1097/01.WNF.0000232277.68501.08.

Tsuboi, Y and Yamada, T and Chaudhuri, RK and Martinez-Martin, P and Schapira, AH and P International, (2006) Comparison of profile of non motor symptoms in Japanese patients with PD with Euoprean patients and healthy controls. Extension of the NMSQuest study. In: MOVEMENT DISORDERS. (pp. S648 - S649). WILEY-LISS

2005

Baracca, A and Solaini, G and Sgarbi, G and Lenaz, G and Baruzzi, A and Schapira, AHV and Martinuzzi, A and Carelli, V (2005) Severe impairment of complex I-Driven adenosine triphosphate synthesis in Leber hereditary optic neuropathy cybrids. ARCH NEUROL-CHICAGO , 62 (5) 730 - 736.

Cano, SJ and Hobart, JC and Hart, PE and Korlipara, LVP and Schapira, AH and Cooper, JM (2005) International Cooperative Ataxia Rating Scale (ICARS): Appropriate for studies of Friedreich's ataxia? MOVEMENT DISORD , 20 (12) 1585 - 1591. 10.1002/mds.20651.

Chaudhuri, KR and Martinez-Martin, P and Schapira, AHV and Ondo, W and Sethi, K and PD NMS Scale Dev Grp, (2005) An international multicentre study validating the first screening questionnaire (NMS-quest) for comprehensive assessment of non motor symptoms of Parkinson's disease. In: MOVEMENT DISORDERS. (pp. S50 - S50). WILEY-LISS

Danielson, SR and Carelli, V and Tan, GL and Martinuzzi, A and Schapira, AHV and Savontaus, ML and Cortopassi, GA (2005) Isolation of transcriptomal changes attributable to LHON mutations and the cybridization process. BRAIN , 128 1026 - 1037. 10.1093/brain/awh447.

Gu, M and Iravani, MM and Cooper, JM and King, D and Jenner, P and Schapira, AHV (2005) Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms (vol 91, pg 1075, 2004). J NEUROCHEM , 92 (1) 215 - 215. 10.1111/j.1471-4159.2004.02966.x.

Hart, PE and Lodi, R and Rajagopalan, B and Bradley, JL and Crilley, JG and Turner, C and Blamire, AM and Manners, D and Styles, P and Schapira, AHV and Cooper, JM (2005) Antioxidant treatment of patients with Friedreich ataxia - Four-year follow-up. ARCH NEUROL-CHICAGO , 62 (4) 621 - 626.

Lo, S and Tolner, B and Taanman, JW and Cooper, JM and Gu, M and Hartley, JA and Schapira, AHV and Hochhauser, D (2005) Assessment of the significance of mitochondrial DNA damage by chemotherapeutic agents. INT J ONCOL , 27 (2) 337 - 344.

Schapira, A and Bate, G and Kirkpatrick, P (2005) Rasagiline. Nat Rev Drug Discov , 4 (8) 625 - 626. 10.1038/nrd1803.

Schapira, AH (2005) Rasagiline, a novel second generation MAO-B inhibitor - pharmacological profile. EUR J NEUROL , 12 329 - 329.

Schapira, AH (2005) Mitochondrial DNA and disease: what happens when things go wrong? The Biochemist , 27 (3) 24 - 27.

Schapira, AHV (2005) Present and future drug treatment for Parkinson's disease. J NEUROL NEUROSUR PS , 76 (11) 1472 - 1478. 10.1136/jnnp.2004.035980.
An open access publication

Schapira, AHV and Olanow, CW (2005) Principles of treatment in Parkinson's disease. Butterworth-Heinemann

Strand, AD and Aragaki, AK and Shaw, D and Bird, T and Holton, J and Turner, C and Tapscott, SJ and Tabrizi, SJ and Schapira, AH and Kooperberg, C and Olson, JM (2005) Gene expression in Huntington's disease skeletal muscle: a potential biomarker. HUM MOL GENET , 14 (13) 1863 - 1876. 10.1093/hmg/ddi192.

Taanman, JW and Schapira, AHV (2005) Analysis of the trinucleotide CAG repeat from the DNA polymerase gamma gene (POLG) in patients with Parkinson's disease. NEUROSCI LETT , 376 (1) 56 - 59. 10.1016/j.neulet.2004.11.023.

Tabrizi, SJ and Blamire, AM and Manners, DN and Rajagopalan, B and Styles, P and Schapira, AHV and Warner, TT (2005) High-dose creatine therapy for Huntington disease: A 2-year clinical and MRS study. NEUROLOGY , 64 (9) 1655 - 1656.

2004

Beretta, S and Mattavelli, L and Sala, G and Tremolizzo, L and Schapira, AHV and Martinuzzi, A and Carelli, V and Ferrarese, C (2004) Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines. BRAIN , 127 2183 - 2192. 10.1093/brain/awh258.

Bradley, J.L. and Homayoun, S. and Hart, P.E. and Schapira, A.H.V. and Cooper, J.M. (2004) Role of oxidative damage in Friedreich's Ataxia. Neurochemical Research , 29 (3) pp. 561-567. 10.1023/B:NERE.0000014826.00881.c3.

Bradley, JL and Homayoun, S and Hart, PE and Schapira, AHV and Cooper, JM (2004) Role of oxidative damage in Friedreich's ataxia. NEUROCHEM RES , 29 (3) 561 - 567.

Chaudhuri, K and Schapira, AH and Martinez-Martin, P and Brown, K (2004) On behalf of the International Parkinson's Disese Non-Motor Symptom Scale Development Group. Can we improve the holistic assessment of Parkinson's disease? The development of a non-motor symptom questionnaire adn scale for PD:. Advances in Clinical Neuroscience and Rehabilitation , 4 20 - 21.

Chaudhuri, KR and Forbes, A and Grosset, D and Lees, A and Shneerson, J and Schapira, A and Stillman, P and Williams, A (2004) Diagnosing restless legs syndrome (RLS) in primary care. CURR MED RES OPIN , 20 (11) 1785 - 1795. 10.1185/030079904X5472.

Chaudhuri, KR and Schapira, AHV and Martinez-Martin, P and Sethi, K and MacPhee, G and Brown, R and Odin, P and Koller, W and Olanow, W and International Nonmotor Symptom, (2004) Development and pilot study of the first nonmotor symptom screening questionnaire and scale for Parkinson's disease using an international multidisciplinary approach. In: MOVEMENT DISORDERS. (pp. 1120 - 1120). WILEY-LISS

Davie, CA and Schapira, AH (2004) Use of COMT inhibitors in the treatment of Parkinson's disease. Clinical Geriatrics , 12 (6) 19 - 24.

Francis, J and Cooke, F and Bradley, JL and Blamire, AM and Schapira, AHV and Neubauer, S and Cooper, JM and Rajagopalan, B (2004) Myocardial. hypertrophy in Friedreich's ataxia (FA) is a function of duration of the disease and the length of the GAA trinucleotide repeat; A cross sectional MRI study. In: HEART. (pp. A58 - A58). B M J PUBLISHING GROUP

Gu, M and Irvani, M and Cooper, JM and King, D and Jenner, P and Schapira, AHV (2004) Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms. J NEUROCHEM , 91 (5) 1075 - 1081. 10.1111/j.1471-4159.2004.02804.x.

Korlipara, LVP and Cooper, JM and Schapira, AHV (2004) Oxidative stress in a neuronal model of alpha synuclein overexpression. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1226 - 1226). B M J PUBLISHING GROUP

Korlipara, LVP and Cooper, JM and Schapira, AHV (2004) Differences in toxicity of the catechol-O-methyl transferase inhibitors, tolcapone and entacapone to cultured human neuroblastoma cells. NEUROPHARMACOLOGY , 46 (4) 562 - 569. 10.1016/j.neuropharm.2003.10.015.

MacMahon, D and Koller, W and Martinex-Martin, P and Chaudhuri, K and Schapira, A and Sethi, K and Brown, R (2004) Can we improve the holistic assessment of Parkinson's disease? The development of a non-motor symptom questionnaire and scale for Parkinson's disease. Advances in Clinical Opinions , 20 1785 - 1795.

McCabe, DJH and Turner, NC and Chao, D and Leff, A and Gregson, NA and Womersley, HJ and Mak, I and Perkin, GD and Schapira, AHV (2004) Paraneoplastic "stiff person syndrome" with metastatic adenocarcinoma and anti-Ri antibodies. NEUROLOGY , 62 (8) 1402 - 1404.

Olanow, CW and Schapira, AHV (2004) Measuring the effects of therapy in Parkinson disease - Reply. JAMA-J AM MED ASSOC , 291 (20) 2431 - 2431.

Orth, M and Tabrizi, SJ and Tomlinson, C and Messmer, K and Korlipara, LVP and Scapira, AHV and Cooper, JM (2004) G209A mutant alpha synuclein expression specifically enhances dopamine induced oxidative damage. NEUROCHEM INT , 45 (5) 669 - 676. 10.1016/j.neuint.2004.03.029.

Page, RA and Davie, CA and MacManus, D and Miszkiel, KA and Walshe, JM and Miller, DH and Lees, AJ and Schapira, AHV (2004) Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease. NEUROLOGY , 63 (4) 638 - 643.

Rafique, R and Schapira, AHV and Cooper, JM (2004) Mitochondrial respiratory chain dysfunction in ageing; Influence of vitamin E deficiency. FREE RADICAL RES , 38 (2) 157 - 165. 10.1080/10715760310001643311.

Samii, A and Nutt, JG and Ransom, BR (2004) Parkinson's disease. (Vol.363).

Schapira, A (2004) Understanding Parkinson's Disease. Pool: Family Doctor Association. British Medical Association: London.

Schapira, A and Lodi, R (2004) Assessment of in vitro and in vivo mitochondrial function in Friedreich's ataxia and Huntington's disease. Methods Mol Biol , 277 293 - 307. 10.1385/1-59259-804-8:293.

Schapira, AH (2004) Excessive daytime sleepiness in Parkinson's disease. NEUROLOGY , 63 (8) S24 - S27.

Schapira, AH (2004) Disease modification in Parkinson's disease. Lancet Neurol , 3 (6) 362 - 368. 10.1016/S1474-4422(04)00769-0.

Schapira, AH (2004) Disease of muscle and the neuromuscular junction. Clinical Neurology 130 - 153.

Schapira, AHV (2004) Disease modification in Parkinson's disease. (vol 3, pg 362, 2004). LANCET NEUROL , 3 (7) 443 - 443.

Schapira, AHV (2004) Restless legs syndrome - An update on treatment options. DRUGS , 64 (2) 149 - 158.

Schapira, AHV and Chaudhuri, KR and Gershanik, O and Stocchi, F (2004) Understanding the importance of the nocturnal symptoms of Parkinson's disease: Diagnosis, treatment, and quality of life. EUR J NEUROL , 11 357 - 357.

Schapira, AHV and Olanow, CW (2004) Neuroprotection in Parkinson disease - Mysteries, myths, and misconceptions. JAMA-J AM MED ASSOC , 291 (3) 358 - 364.

Tabrizi, SJ and Blamire, AM and Rajagopalan, B and Manners, D and Schapira, AH and Warner, TT (2004) High dose creatine therapy for Huntington's disease: Clinical and 31 phosphorous magnetic resonance spectroscopy ((31P) MRS) findings in a 2-year study. In: MOVEMENT DISORDERS. (pp. S51 - S51). WILEY-LISS

Wilkinson, PA and Crosby, AH and Turner, C and Bradley, LJ and Ginsberg, L and Wood, NW and Schapira, AH and Warner, TT (2004) A clinical, genetic and biochemical study of SPG7 mutations in hereditary spastic paraplegia. BRAIN , 127 973 - 980. 10.1093/brain/awh125.

2003

Cooper, JM and Schapira, AHV (2003) Friedreich's Ataxia: Disease mechanisms, antioxidant and coenzyme Q(10) therapy. BIOFACTORS , 18 (1-4) 163 - 171.

Cortopassi, G and Tong, W and Wong, A and Carelli, V and Martinuzzi, A and Schapira, AHV and Danielson, SR (2003) Mitochondrial fusion and Leber's hereditary optic neuropathy mtDNA point mutations cause altered nuclear gene expression. In: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. (pp. U395 - U395). ASSOC RESEARCH VISION OPHTHALMOLOGY INC

Ghelli, A and Zanna, C and Porcelli, AM and Schapira, AH and Martinuzzi, A and Carelli, V and Rugolo, M (2003) Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium. Journal of Biological Chemistry , 278 (6) 4146 - 4150.
An open access publication

Ghelli, A and Zanna, C and Porcelli, AM and Schapira, AHV and Martinuzzi, A and Carelli, V and Rugolo, M (2003) Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium. J BIOL CHEM , 278 (6) 4145 - 4150. 10.1074/jbc.M210285200.
An open access publication

Lodi, R and Rajagopalan, B and Schapira, AHV and Cooper, JM (2003) Cardiac bioenergetics in Friedreich's ataxia. ANN NEUROL , 54 (4) 552 - 552. 10.1002/ana.10744.

Lodi, R and Rajagopalan, B and Schapira, AHV and Hart, P and Crilley, JG and Bradley, JL and Blamire, AM and Manners, D and Styles, P and Cooper, JM (2003) Coenzyme Q10 and vitamin E treatment in patients with Friedreich ataxia improves cardiac bioenergetics and mechnical function. A 4 year clinical and 31 P-magnetic resonance spectroscopy study. In: HEART. (pp. A43 - A43). B M J PUBLISHING GROUP

Miller, RF and Shahmanesh, M and Hanna, MG and Unwin, RJ and Schapira, AHV and Weller, IVD (2003) Polyphenotypic expression of mitochondrial toxicity caused by nucleoside reverse transcriptase inhibitors. ANTIVIR THER , 8 (3) 253 - 257.

Olanow, CW and Schapira, AHV and Agid, Y (2003) Neuroprotection for Parkinson's disease: Prospects and promises. ANN NEUROL , 53 S1 - S2.

Orth, M and Cooper, JM and Bates, GP and Schapira, AHV (2003) Inclusion formation in Huntington's disease R6/2 mouse muscle cultures. J NEUROCHEM , 87 (1) 1 - 6. 10.1046/j.1471-4159.2003.02009.x.

Orth, M and Tabrizi, SJ and Schapira, AHV and Cooper, JM (2003) alpha-Synuclein expression in HEK293 cells enhances the mitochondrial sensitivity to rotenone. NEUROSCI LETT , 351 (1) 29 - 32. 10.1016/S0304-3940(03)00941-8.

Schapira, AHV (2003) Disease-modifying strategies and challenges in PD - Interactive breakout sessions. NEUROLOGY , 61 (6) S56 - S63.

Schapira, AHV (2003) Neuroprotection in PD - A role for dopamine agonists? NEUROLOGY , 61 (6) S34 - S42.

Schapira, AHV (2003) Progress in Parkinson's disease. NEUROLOGY , 61 (6) S1 - S3.

Schapira, AHV (2003) Diseases of muscle and the neuromuscular junction. In: Fowler, TJ and Scadding, JW, (eds.) Clinical neurology. (130 - 153). Arnold: London.

Schapira, AHV and Gu, M and Cooper, JM (2003) Dopamine agonist mediated neuroprotection: Mechanisms of action. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1179 - 1179). BRITISH MED JOURNAL PUBL GROUP

Schapira, AHV and Olanow, CW (2003) Rationale for the use of dopamine agonists as neuroprotective agents in Parkinson's disease. ANN NEUROL , 53 S149 - S157. 10.1002/ana.10514.

Tabrizi, SJ and Blamire, AM and Manners, DN and Rajagopalan, B and Styles, P and Schapira, AHV and Warner, TT (2003) Creatine therapy for Huntington's disease: Clinical and MRS findings in a 1-year pilot study. NEUROLOGY , 61 (1) 141 - 142.

Turner, C and Schapira, AHV (2003) Energy metabolism and Huntington's disease. In: Bates, G and Harper, P and Jones, L, (eds.) Huntington's disease. Oxford University Press

Warner, TT and Schapira, AHV (2003) Genetic and environmental factors in the cause of Parkinson's disease. ANN NEUROL , 53 S16 - S23. 10.1002/ana.10487.

Wilkinson, PA and Crosby, AH and Turner, C and Patel, H and Wood, NW and Schapira, AH and Warner, TT (2003) A clinical and genetic study of SPG5A linked autosomal recessive hereditary spastic paraplegia. NEUROLOGY , 61 (2) 235 - 238.

2002

Bentley, PI and Kimber, T and Schapira, AHV (2002) Painful third nerve palsy in MS. NEUROLOGY , 58 (10) 1532 - 1532.

Bradley, JL and Hart, PE and Al Khayatt, M and Schapira, AH and Cooper, J (2002) Validation and use of assessment protocols to determine clinical progression in Friedreich's ataxia. In: MOVEMENT DISORDERS. (pp. S315 - S315). WILEY-LISS

Bradley, JL and Schapira, AH and Cooper, JM (2002) Therapies for Friedreich's ataxia. EuroAtaxia Newsletter , 22 8 - 11.

Cock, HR and Schapira, AHV (2002) A comparison of lorazepam and diazepam as initial therapy in convulsive status epilepticus. QJM-INT J MED , 95 (4) 225 - 231.

Cock, HR and Tong, X and Hargreaves, IP and Heales, SJR and Clark, JB and Patsalos, PN and Thom, M and Groves, M and Schapira, AHV and Shorvon, SD and Walker, MC (2002) Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat. EPILEPSY RES , 48 (3) 157 - 168.

Danielson, SR and Wong, A and Carelli, V and Martinuzzi, A and Schapira, AHV and Cortopassi, GA (2002) Cells bearing mutations causing Leber's hereditary optic neuropathy are sensitized to Fas-induced apoptosis. J BIOL CHEM , 277 (8) 5810 - 5815. 10.1074/jbc.M110119200.
An open access publication

Davie, CA and Schapira, AHV (2002) Wilson disease. In: UNSPECIFIED (175 - 190). ACADEMIC PRESS INC

DiMauro, S and Schapira, AHV (2002) Mitochondrial encephalomyopathies. In: Asbury, AK and McKhann, GM and McDonald, WI and Goadsby, PJ and McArthur, JC, (eds.) Diseases of the nervous system: clinical neuroscience and therapeutic principles. (1922 - 1936). Cambridge University Press: Cambridge.

Hart, PE and De Vivo, DC and Schapira, AH (2002) Clinical features of the mitochondrial encephalomyopathies. In: Schapira, AH and DiMauro, S, (eds.) Mitochondrial Disorders in Neurology. (35 - 68). Butterworth Heinemann: Massachusetts.

Korlipara, LP and Messmer, K and Cooper, JM and Schapira, AHV (2002) Overexpression of wild-type and mutant alpha-synuclein in a neuroblastoma cell line. In: MOVEMENT DISORDERS. (pp. S61 - S61). WILEY-LISS

Korlipara, LV and Schapira, AH (2002) Parkinson's disease. In: UNSPECIFIED (283 - 314).

Korlipara, LVP and Burn, DJ and Schapira, AHV (2002) Juvenile-onset parkinsonism in a patient with Chediak-Higashi syndrome: A case report. In: MOVEMENT DISORDERS. (pp. S254 - S254). WILEY-LISS

Korlipara, LVP and Schapira, AH (2002) Possible Mechanisms Underlying the Protective Action of Immunosuppressants Against Parkinson's Disease. The Mitochondrial Permeability Transition Pore Hypothesis. In: Borlongan, CV and Isacson, O and Sanberg, PR, (eds.) Immunosuppressant Analogs in Neuroprotection. (105 - 137). Humana Press: Totowa, New Jersey.

Korlipara, LVP and Schapira, AHV (2002) Neuroprotection in Parkinson's disease. MAPPING THE PROGRESS OF ALZHEIMER'S AND PARKINSON'S DISEASE , 51 373 - 378.

Korlipara, LVP and Schapira, AHV (2002) Parkinson's disease. INT REV NEUROBIOL , 53 283 - 314.

Lodi, R and Rajagopalan, B and Bradley, JL and Taylor, DJ and Crilley, JG and Hart, PE and Blamire, AM and Manners, D and Styles, P and Schapira, AHV and Cooper, JM (2002) Mitochondrial dysfunction in Friedreich's ataxia: From pathogenesis to treatment perspectives. FREE RADICAL RESEARCH , 36 (4) 461 - 466. 10.1080/10715760290021324.

Lodi, R and Rajagopalan, B and Crilley, JG and Cooper, JM and Styles, P and Schapira, AHV (2002) Cardiac hypertrophy in Friedreich's ataxia - Reply to letter to the editor. CARDIOVASC RES , 54 (3) 695 - 696.

Orrell, R and Schapira, AH (2002) Mitochondria and amyotrophic lateral sclerosis. International Review of Neurobiology , 53 411 - 424.

Orrell, RW and Schapira, AHV (2002) Mitochondria and amyotrophic lateral sclerosis. In: UNSPECIFIED (411 - 426). ACADEMIC PRESS INC

Orth, M and Schapira, AHV (2002) Mitochondrial involvement in Parkinson's disease. NEUROCHEM INT , 40 (6) 533 - 541.

Schapira, AH (2002) Mitochondrial Function and Dysfunction. International Review of Neurobiology: Vol.53. Academic Press

Schapira, AH and DiMauro, S (2002) Mitochondrial Disorders in Neurology. (2nd ed.). Butterworth Heinemann: Massachusetts.

Schapira, AHV (2002) Dopamine agonists and neuroprotection in Parkinson's diseae. EUR J NEUROL , 9 7 - 14.

Schapira, AHV (2002) Primary and secondary defects of the mitochondrial respiratory chain. JOURNAL OF INHERITED METABOLIC DISEASE , 25 (3) 207 - 214.

Schapira, AHV (2002) Neuroprotection and dopamine agonists. NEUROLOGY , 58 (4) S9 - S18.

Schapira, AHV (2002) The "new" mitochondrial disorders. J NEUROL NEUROSUR PS , 72 (2) 144 - 149.

Schapira, AHV and Gu, M and King, DF and Cooper, JM and Jenner, P (2002) Pramipexole protects against rotenone toxicity: Mechanisms and implications. NEUROLOGY , 58 (7) A495 - A495.

Spacey, SD and Valente, EM and Wali, GM and Warner, TT and Jarman, PR and Schapira, AHV and Dixon, PH and Davis, MB and Bhatia, KP and Wood, NW (2002) Genetic and clinical heterogeneity in paroxysmal kinesigenic dyskinesia: Evidence for a third EKD gene. MOVEMENT DISORD , 17 (4) 717 - 725. 10.1002/mds.10126.

Tabrizi, SJ and Rajagopalan, B and Styles, P and Manners, D and Schapira, AH and Warner, TT (2002) Creatine therapy for Huntington's disease (HD): Clinical and-(31)phosphorous magnetic resonance spectroscopy (P-31 MRS) findings in a one year pilot. In: MOVEMENT DISORDERS. (pp. S319 - S319). WILEY-LISS

Tabrizi, SJ and Schapira, AHV (2002) Mitochondrial abnormalities in neurodegenerative disorders. In: Schapira, AHV and DiMauro, S, (eds.) Mitochondrial disorders in neurology 2. (143 - 174). Butterworth-Heinemann: Oxford.

Turner, C and Jones, L and Cooper, JM and Schapira, AHV (2002) The characterization of Huntington's disease (HD) skeletal muscle: Mitochondrial respiratory chain, ultrastructural and light microscopic study. In: MOVEMENT DISORDERS. (pp. S325 - S325). WILEY-LISS

Turner, C and Jones, L and Elliston, L and Cooper, JM and Schapira, AHV (2002) In vitro cell models of Huntington's disease using N-terminal and full-length huntingtin: The relationship between excitotoxicity, mitochondrial dysfunction, and free radicals. In: MOVEMENT DISORDERS. (pp. S320 - S321). WILEY-LISS

Turner, C and Schapira, AH (2002) Energy metabolism and Huntington's Disease. In: Bates, GP and Harper, P and Jones, L, (eds.) Huntington's Disease. (309 - 323). Oxford University Press: Oxford.

2001

Bhatia, K and Brooks, DJ and Burn, DJ and Clarke, CE and Grosset, DG and MacMahon, DG and Playfer, J and Schapira, AHV and Stewart, D and Widliams, AC and Parkinsons Dis Consensus Working G, (2001) Updated guidelines for the management of Parkinson's disease. HOSP MED , 62 (8) 456 - 470.

Cleeter, MW and Cooper, JM and Schapira, AH (2001) Nitric Oxide enhances MPP+ inhibition of complex I. FEBS Letters , 24 (502(1-2)) 50 - 52. 10.1016/S0014-5793(01)02763-6.

Cleeter, MWJ and Cooper, JM and Schapira, AHV (2001) Nitric oxide enhances MPP+ inhibition of complex I. FEBS LETT , 504 (1-2) 50 - 52.

Cock, HR and Schapira, AHV (2001) Mitochondrial myopathies. In: Rose, FC, (ed.) Twentieth Century Neurology: The British Contribution. (255 - 281). Imperial College Press: London.

King, DF and Cooper, JM and Schapira, AHV (2001) Pramipexole protects against MPP+ toxicity in SHSY5Y cells by maintaining mitochondrial membrane potential. NEUROLOGY , 56 (8) A377 - A378.

Kingsbury, AE and Cooper, M and Schapira, AHV and Foster, OJF (2001) Metabolic enzyme expression in dopaminergic neurons in Parkinson's disease: An in situ hybridization study. ANN NEUROL , 50 (2) 142 - 149.

Lodi, R and Hart, PE and Rajagopalan, B and Taylor, DJ and Crilley, JG and Bradley, JL and Blamire, AM and Manners, D and Styles, P and Schapira, AHV and Cooper, JM (2001) Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia. ANN NEUROL , 49 (5) 590 - 596.

Lodi, R and Rajagopalan, B and Blamire, AM and Cooper, JM and Davies, CH and Bradley, JL and Styles, P and Schapira, AHV (2001) Cardiac energetics are abnormal in Friedreich ataxia patients in the absence of cardiac dysfunction and hypertrophy: An in vivo P-31 magnetic resonance spectroscopy study. CARDIOVASC RES , 52 (1) 111 - 119.

Lodi, R and Taylor, DJ and Schapira, AHV (2001) Mitochondrial dysfunction in Friedreich's ataxia. BIOL SIGNAL RECEPT , 10 (3-4) 263 - 270.

Lodi, R. and Hart, P.E. and Rajagopalan, B. and Taylor, D.J. and Crilley, J.G. and Bradley, J.L. and Blamire, A.M. and Manners, D. and Styles, P. and Schapira, A.H.V. and Cooper, J.M. (2001) Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia. Annals of Neurology , 49 (5) pp. 590-596. 10.1002/ana.1001.

Lodi, R. and Rajagopalan, B. and Blamire, A.M. and Cooper, J.M. and Davies, C.H. and Bradley, J.L. and Styles, P. and Schapira, A.H.V. (2001) Cardiac energetics are abnormal in Friedreich ataxia patients in the absence of cardiac dysfunction and hypertrophy: an in vivo 31P magnetic resonance spectroscopy study. Cardiovascular Research , 52 (1) pp. 111-119. 10.1016/S0008-6363(01)00357-1.

Orrell, R and Schapira, AHV (2001) Asymmetric muscle weakness. In: Schapira, AHV and Rowland, LP, (eds.) Clinical cases in neurology. (239 - 245). Butterworth-Heinemann: Oxford.

Orrell, R and Schapira, AHV (2001) Muscle weakness and dysphagia. In: Schapira, AHV and Rowland, LP, (eds.) Clinical cases in neurology. (99 - 106). Butterworth-Heinemann: Oxford.

Orth, M and Schapira, AHV (2001) Prion codon 129 homozygosity and sporadic inclusion body myositis - Reply. NEUROLOGY , 57 (2) 368 - 368.

Orth, M and Schapira, AHV (2001) Mitochondria and degenerative disorders. AM J MED GENET , 106 (1) 27 - 36.

Page, RA and Davie, CA and MacManus, D and Dooley, J and Walshe, J and Miller, DH and Lees, AJ and Schapira, AHV (2001) Magnetic resonance spectroscopy of patients with Wilson's disease. J NEUROL NEUROSUR PS , 70 (2) 274 - 275.

Rafique, R and Schapira, AHV and Cooper, JM (2001) Sensitivity of respiratory chain activities to lipid peroxidation: effect of vitamin E deficiency. BIOCHEM J , 357 887 - 892.

Rafique, R. and Schapira, A.H.V. and Cooper, J.M. (2001) Sensitivity of respiratory chain activities to lipid peroxidation: effect of vitamin E deficiency. Biochemical Journal , 357 (3) pp. 887-892. 10.1042/0264-6021:3570887.

Schapira, A and Ed, (2001) Clinical cases in neurology. Butterworth-Heinemann: Oxford.

Schapira, AHV (2001) Causes of neuronal death in Parkinson's disease. ADV NEUROL , 86 155 - 162.

Schapira, AHV and Orrell, R (2001) Young onset stroke. In: Schapira, AHV and Rowland, LP, (eds.) Clinical cases in neurology. (177 - 182). Butterworth-Heinemann: Oxford.

Sharma, P and Wang, T and Brown, MJ and Schapira, AHV (2001) Fits and strokes. LANCET , 358 (9276) 120 - 120.

Shults, CW and Schapira, AHV (2001) A cue to queue for CoQ? NEUROLOGY , 57 (3) 375 - 376.

Silva, MT and Schapira, AHV (2001) Parkinson's disease. In: Mattson, MP, (ed.) Pathogenesis of neurodegenerative disorders. (53 - 79). Humana Press: Totowa,N.J..

Turner, C and Schapira, AHV (2001) Mitochondrial dysfunction in neurodegenerative disorders and ageing. NEUROPATHOLOGY AND GENETICS OF DEMENTIA , 487 229 - 251.

Williams, SL and Scholte, HR and Gray, RGF and Leonard, JV and Schapira, AHV and Taanman, JW (2001) Immunological phenotyping of fibroblast cultures from patients with a mitochondrial respiratory chain deficit. LAB INVEST , 81 (8) 1069 - 1077.

Wyttenbach, A and Swartz, J and Kita, H and Thykjaer, T and Carmichael, J and Bradley, J and Brown, R and Maxwell, M and Schapira, A and Orntoft, TF and Kato, K and Rubinsztein, DC (2001) Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet , 10 (17) 1829 - 1845.

2000

Attimonelli, M and Altamura, N and Benne, R and Brennicke, A and Cooper, JM and D'Elia, D and de Montalvo, A and de Pinto, B and De Robertis, M and Golik, P and Knoop, V and Lanave, C and Lazowska, J and Licciulli, F and Malladi, BS and Memeo, F and Monnerot, M and Pasimeni, R and Pilbout, S and Schapira, AHV and Sloof, P and Saccone, C (2000) MitBASE: a comprehensive and integrated mitochondrial DNA database. The present status. NUCLEIC ACIDS RES , 28 (1) 148 - 152.
An open access publication

Bradley, JL and Blake, JC and Chamberlain, S and Thomas, PK and Cooper, JM and Schapira, AHV (2000) Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia. HUM MOL GENET , 9 (2) 275 - 282.

Gu, M and Cooper, JM and Butler, P and Walker, AP and Mistry, PK and Dooley, JS and Schapira, AHV (2000) Oxidative phosphorylation defects in Wilson's disease liver. HEPATOLOGY , 32 (4) 487A - 487A.

Gu, M and Cooper, JM and Butler, P and Walker, AP and Mistry, PK and Dooley, JS and Schapira, AHV (2000) Oxidative-phosphorylation defects in liver of patients with Wilson's disease. LANCET , 356 (9228) 469 - 474.

Leonard, JV and Schapira, AHV (2000) Mitochondrial respiratory chain disorders II: neurodegenerative disorders and nuclear gene defects. LANCET , 355 (9201) 389 - 394.

Leonard, JV and Schapira, AHV (2000) Mitochondrial respiratory chain disorders I: mitochondrial DNA defects. LANCET , 355 (9200) 299 - 304.

Lo, SK and Tolner, B and Rogers, G and Schapira, AHV and Hartley, JA and Hochhauser, D (2000) Assessment of mitochondrial DNA damage by chemotherapeutic agents. BRIT J CANCER , 83 22 - 22.

Lodi, R and Schapira, AHV and Manners, D and Styles, P and Wood, NW and Taylor, DJ and Warner, TT (2000) Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy. ANN NEUROL , 48 (1) 72 - 76.

Munchau, A and Valente, EM and Shahidi, GA and Eunson, LH and Hanna, RG and Quinn, NP and Schapira, AHV and Wood, NW and Bhatia, KP (2000) A new family with paroxysmal exercise induced dystonia and migraine: a clinical and genetic study. J NEUROL NEUROSUR PS , 68 (5) 609 - 614.

Olanow, CW and Schapira, AHV and Rascol, O (2000) Continuous dopamine-receptor stimulation in early Parkinson's disease. TRENDS NEUROSCI , 23 (10) S117 - S126.

Olanow, CW and Schapira, AHV and Rascol, O (2000) Continous dopamine-receptor stimulation in early Parkinson's disease. Trends in Neurosciences , 23(iss (10 Sup) S117 - S126.

Olanow, CW and Schapira, AHV and Roth, T (2000) Waking up to sleep episodes in Parkinson's disease. MOVEMENT DISORD , 15 (2) 212 - 215.

Olanow, CW and Schapira, AHV and Roth, T (2000) Falling asleep at the wheel: Motor vehicle mishaps in people taking pramipexole and ropinirole. NEUROLOGY , 54 (1) 274 - 274.

Orth, M and Tabrizi, SJ and Schapira, AHV (2000) Sporadic inclusion body myositis not linked to prion protein codon 129 methionine homozygosity. NEUROLOGY , 55 (8) 1235 - 1235.

Rahman, S and Lake, BD and Taanman, JW and Hanna, MG and Cooper, JM and Schapira, AHV and Leonard, JV (2000) Cytochrome oxidase immunohistochemistry: clues for genetic mechanisms. BRAIN , 123 591 - 600.

Schapira, AHV (2000) Overview: sleep disturbances in Parkinson's disease. EUR J NEUROL , 7 1 - 2.

Schapira, AHV (2000) The aetiology and management of sleep episodes in Parkinson's disease. EUROPEAN JOURNAL OF NEUROLOGY , 7 36 - 40.

Schapira, AHV (2000) Mitochondrial disorders. CURR OPIN NEUROL , 13 (5) 527 - 532.

Schapira, AHV (2000) Sleep attacks (sleep episodes) with pergolide. LANCET , 355 (9212) 1332 - 1333.

Schapira, AHV (2000) Parkinson's disease: examining neuroprotective strategies. Geriatric Medicine , 30 (11) 39 - 42.

Schapira, AHV and Obeso, JA and Olanow, CW (2000) The place of COMT inhibitors in the armamentarium of drugs for the treatment of Parkinson's disease. NEUROLOGY , 55 (11) S65 - S68.

Taanman, JW and Williams, SL and Morris, AAM and Cooper, JM and Clayton, PT and Leonard, JV and Schapira, AHV (2000) Mitochondrial DNA depletion syndrome: A familial disorder showing variable clinical penetration. ANN NEUROL , 48 (3) 438 - 438.

Tabrizi, SJ and Orth, M and Wilkinson, JM and Taanman, JW and Warner, TT and Cooper, JM and Schapira, AHV (2000) Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity. HUM MOL GENET , 9 (18) 2683 - 2689.

Tabrizi, SJ and Workman, J and Hart, PE and Mangiarini, L and Mahal, A and Bates, G and Cooper, JM and Schapira, AHV (2000) Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse. ANN NEUROL , 47 (1) 80 - 86.

1999

Attimonelli, M and Altamura, N and Benne, R and Boyen, C and Brennicke, A and Carone, A and Cooper, JM and D'Elia, D and de Montalvo, A and de Pinto, B and De Robertis, M and Golik, P and Grienenberger, JM and Knoop, V and Lanave, C and Lazowska, J and Lemagnen, A and Malladi, BS and Memeo, F and Monnerot, M and Pilbout, S and Schapira, AHV and Sloof, P and Slonimski, P and Stevens, K and Saccone, C (1999) MitBASE: a comprehensive and integrated mitochondrial DNA database. NUCLEIC ACIDS RES , 27 (1) 128 - 133.
An open access publication

Attimonelli, M and Cooper, JM and D'Elia, D and de Montalvo, A and De Robertis, M and Lehvaslaiho, H and Malladi, SB and Memeo, F and Stevens, K and Schapira, AHV and Saccone, C (1999) Update of the human MitBASE database. NUCLEIC ACIDS RES , 27 (1) 143 - 146.
An open access publication

Blake, JC and Taanman, JW and Morris, AMM and Gray, RGF and Cooper, JM and McKiernan, PJ and Leonard, JV and Schapira, AHV (1999) Mitochondrial DNA depletion syndrome is expressed in amniotic fluid cell cultures. AM J PATHOL , 155 (1) 67 - 70.

Chalmers, RM and Schapira, AHV (1999) Clinical, biochemical and molecular genetic features of Leber's hereditary optic neuropathy. BBA-BIOENERGETICS , 1410 (2) 147 - 158.

Cock, H and Schapira, AHV (1999) Mitochondrial DNA mutations and mitochondrial dysfunction in epilepsy. EPILEPSIA , 40 33 - 40.

Cock, HR and Cooper, JM and Schapira, AHV (1999) Functional consequences of the 3460-bp mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. J NEUROL SCI , 165 (1) 10 - 17.

Hart, PE and Schapira, AHV (1999) Mitochondria: Aspects for neuroprotection. DRUG DEVELOP RES , 46 (1) 57 - 66.

Lodi, R and Cooper, JM and Bradley, JL and Manners, D and Styles, P and Taylor, DJ and Schapira, AHV (1999) Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia. P NATL ACAD SCI USA , 96 (20) 11492 - 11495.

Newman, B and Meola, G and O'Donovan, DG and Schapira, AHV and Kingston, H (1999) Proximal myotonic myopathy (PROMM) presenting as myotonia during pregnancy. NEUROMUSCULAR DISORD , 9 (3) 144 - 149.

Obeso, J and Olanow, W and Schapira, AHV and Toloso, J (1999) Neuronal death and Parkinson's disease. Adis: Madrid.

Rahman, S and Schapira, AHV (1999) Mitochondrial myopathies: clinical features, molecular genetics, investigation, and management. In: Schapira, AHV and Griggs, RC, (eds.) Muscle diseases. (117 - 223). Butterworth Heinemann: Boston.

Rahman, S and Taanman, JW and Cooper, JM and Nelson, I and Hargreaves, I and Meunier, B and Hanna, MG and Garcia, JJ and Capaldi, RA and Lake, BD and Leonard, JV and Schapira, AHV (1999) A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy. AM J HUM GENET , 65 (4) 1030 - 1039.

Schapira, AH (1999) Mitochondrial DNA in Parkinson's disease. In: UNSPECIFIED (233 - 237).

Schapira, AHV (1999) Mitochondria in the aetiology and pathogenesis of Parkinson's disease. PARKINSONISM RELAT D , 5 (4) 139 - 143.

Schapira, AHV (1999) Mitochondrial disorders. BBA-BIOENERGETICS , 1410 (2) 99 - 102.

Schapira, AHV (1999) Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia. BBA-BIOENERGETICS , 1410 (2) 159 - 170.

Schapira, AHV (1999) Science, medicine, and the future - Parkinson's disease. BRIT MED J , 318 (7179) 311 - 314.

Schapira, AHV (1999) Aetiology of Parkinson's disease. In: Obeso, J and Olanow, W and Schapira, AHV and Toloso, J, (eds.) Neuronal death and Parkinson's disease. (41 - 49). Adis: Madrid.

Schapira, AHV (1999) Looking ahead in the treatment of Parkinson's disease. Geriatric Medicine , 28 59 - 62.

Schapira, AHV (1999) Mitochondrial dysfunction in neurodegenerative diseases. Neuroscience News , 2 (5) 43 - 49.

Schapira, AHV (1999) Mitochondrial dysfunction in Parkinson's disease. In: Obeso, J and Olanow, W and Schapira, AHV and Toloso, J, (eds.) Neuronal death and Parkinson's disease. (109 - 120). Adis: Madrid.

Schapira, AHV and Cock, HR (1999) Mitochondrial myopathies and encephalomyopathies. EUR J CLIN INVEST , 29 (10) 886 - 898.

Tabrizi, SJ and Cleeter, MWJ and Xuereb, J and Taanman, JW and Cooper, JM and Schapira, AHV (1999) Biochemical abnormalities and excitotoxicity in Huntington's disease brain. ANN NEUROL , 45 (1) 25 - 32.

Tabrizi, SJ and Schapira, AHV (1999) Secondary abnormalities of mitochondrial DNA associated with neurodegeneration. MITOCHONDRIA AND CELL DEATH (66) 99 - 110.

1998

Attimonelli, M and Calo, D and Cooper, JM and de Montalvo, A and Licciulli, F and Sasanelli, D and Stevens, K and Malladi, BS and Saccone, C and Shapira, AHV (1998) The mitBASE human dataset structure. NUCLEIC ACIDS RESEARCH , 26 (1) 116 - 119. 10.1093/nar/26.1.116.
An open access publication

Bhatia, K and Brooks, DJ and Burn, DJ and Clarke, CE and Playfer, J and Sawle, GV and Schapira, AH and Stewart, D and Williams, AC (1998) Guidelines for the management of Parkinson's disease. The Parkinson's Disease Consensus Working Group. Hosp Med , 59 (6) 469 - 480.

Bhatia, K and Brooks, DJ and Burn, DJ and Clarke, CE and Playfer, J and Sawle, GV and Schapira, AHV and Stewart, D and Williams, AC and Parkinson Dis Consensus Working Grp, (1998) Guidelines for the management of Parkinson's disease. HOSP MED , 59 (6) 469 - 480.

Cock, H and Taanman, J-W and Schapira, AHV (1998) Mitochondrial DNA mutations and nuclear mitochondrial interactions in human disease. In: Papa, C and Guerrieri, F and Tager, JM, (eds.) Frontiers of cellular bioenergetics: molecular biology, biochemistry, and physiopathology. (635 - 663). Pleum Pub Corp: London.

Cock, HR and Tabrizi, SJ and Cooper, JM and Schapira, AHV (1998) The influence of nuclear background on the biochemical expression of 3460 Leber's hereditary optic neuropathy. ANN NEUROL , 44 (2) 187 - 193.

Gu, M and Cooper, JM and Taanman, JW and Schapira, AHV (1998) Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease. ANN NEUROL , 44 (2) 177 - 186.

Gu, M and Owen, AD and Toffa, SEK and Cooper, JM and Dexter, DT and Jenner, P and Marsden, CD and Schapira, AHV (1998) Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases. J NEUROL SCI , 158 (1) 24 - 29.

Hanna, MG and Nelson, IP and Rahman, S and Lane, RJM and Land, J and Heales, S and Cooper, MJ and Schapira, AHV and Morgan-Hughes, JA and Wood, NW (1998) Cytochrome c oxidase deficiency associated with the first stop-codon point mutation in human mtDNA. AM J HUM GENET , 63 (1) 29 - 36.

Hanna, MG and Stewart, J and Schapira, AHV and Wood, NW and Morgan-Hughes, JA and Murray, NMF (1998) Salbutamol treatment in a patient with hyperkalaemic periodic paralysis due to a mutation in the skeletal muscle sodium channel gene (SCN4A). J NEUROL NEUROSUR PS , 65 (2) 248 - 250.

Lees, AJ and Lang, AE (1998) Movement disorders. (Vol.13).

Lodi, R and Cooper, JM and Manners, D and Styles, P and Taylor, DJ and Schapira, AHV (1998) Deficit of mitochondrial respiration in patients with Friedreich's ataxia shown by in vivo P-31 magnetic resonance spectroscopy. ANN NEUROL , 44 (3) 439 - 440.

Lodi, R and Taylor, DJ and Tabrizi, SJ and Hilton-Jones, D and Squier, MV and Seller, A and Styles, P and Schapira, AHV (1998) Normal in vivo skeletal muscle oxidative metabolism in sporadic inclusion body myositis assessed by P-31-magnetic resonance spectroscopy. BRAIN , 121 2119 - 2126.

Morris, AAM and Taanman, JW and Blake, J and Cooper, JM and Lake, BD and Malone, M and Love, S and Clayton, PT and Leonard, JV and Schapira, AHV (1998) Liver failure associated with mitochondrial DNA depletion. J HEPATOL , 28 (4) 556 - 563.

Schapira, AH (1998) Colloidal gold staining and immunodetection in 2D protein mapping. In: UNSPECIFIED (237 - 241).

Schapira, AHV (1998) Inborn and induced defects of mitochondria. ARCH NEUROL-CHICAGO , 55 (10) 1293 - 1296.

Schapira, AHV (1998) Mitochondrial dysfunction in neurodegenerative disorders. BBA-BIOENERGETICS , 1366 (1-2) 225 - 233.

Schapira, AHV (1998) Human complex I defects in neurodegenerative diseases. BBA-BIOENERGETICS , 1364 (2) 261 - 270.

Schapira, AHV (1998) Diseases of muscle and the neuromuscular junction. In: Marsden, CD and Fowler, TJ, (eds.) Clinical Neurology. (105 - 125). Arnold: London.

Schapira, AHV and Gu, M and Taanman, JW and Tabrizi, SJ and Seaton, T and Cleeter, M and Cooper, JM (1998) Mitochondria in the etiology and pathogenesis of Parkinson's disease. ANNALS OF NEUROLOGY , 44 (3) S89 - S98.

Seaton, TA and Cooper, JM and Schapira, AHV (1998) Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins. BRAIN RES , 809 (1) 12 - 17.

Tabrizi, SJ and Cooper, JM and Schapira, AHV (1998) Mitochondrial DNA in focal dystonia: A cybrid analysis. ANN NEUROL , 44 (2) 258 - 261.

Tabrizi, SJ and Schapira, AHV (1998) Primary and secondary deficiencies of the mitochondrial respiratory chain. NEUROLOGIST , 4 (4) 169 - 179.

Turner, LF and Kaddoura, S and Harrington, D and Cooper, JM and Poole-Wilson, PA and Schapira, AHV (1998) Mitochondrial DNA in idiopathic cardiomyopathy. EUR HEART J , 19 (11) 1725 - 1729.

Warner, TT and Schapira, AHV (1998) The role of the alpha-synuclein gene mutation in patients with sporadic Parkinson's disease in the United Kingdom. J NEUROL NEUROSUR PS , 65 (3) 378 - 379.

1997

Blake, JC and Taanman, JW and Leonard, JV and Cooper, JM and Schapira, AHV (1997) Molecular mechanisms in mitochondrial DNA depletion syndrome. NEUROLOGY , 48 (3) 4082 - 4082.

Cock, H and Mandler, R and Ahmed, W and Schapira, AHV (1997) Neuromyelitis optica (Devic's syndrome): No association with the primary mitochondrial DNA mutations found in Leber hereditary optic neuropathy. J NEUROL NEUROSUR PS , 62 (1) 85 - 87.

Cooper, JM and Schapira, AHV (1997) Mitochondrial dysfunction in neurodegeneration. J BIOENERG BIOMEMBR , 29 (2) 175 - 183.

Gu, M and Gash, MT and Cooper, JM and Wenning, GK and Daniel, SE and Quinn, NP and Marsden, CD and Schapira, AHV (1997) Mitochondrial respiratory chain function in multiple system atrophy. MOVEMENT DISORD , 12 (3) 418 - 422.

Hanna, MG and Nelson, IP and Rahman, S and Schapira, AHV and MorganHughes, JA and Wood, NW (1997) Cytochrome c oxidase deficiency associated with a new stop codon mutation in mitochondrial DNA. In: ANN NEUROL. (pp. M79 - M79). LIPPINCOTT-RAVEN PUBL

Hawkes, CH and Macdonald, AM and Schapira, AHV (1997) Use of general practitioner computerised records to create a population based twin sample: pilot study based on Parkinson's disease. BRIT MED J , 315 (7121) 1510 - 1511.

Lodi, R and Taylor, DJ and Tabrizi, SJ and Kumar, S and Sweeney, M and Wood, NW and Styles, P and Radda, GK and Schapira, AHV (1997) In vivo skeletal muscle mitochondrial function in Leber's hereditary optic neuropathy assessed by P-31 magnetic resonance spectroscopy. ANN NEUROL , 42 (4) 573 - 579.

Nashef, L and Lake, BD and Schapira, AHV (1997) Congenital muscular dystrophy with severe retrocollis and mental retardation: A report of two siblings. J NEUROL NEUROSUR PS , 62 (3) 279 - 281.

Olanow, CW and Schapira, AHV (1997) Neuroprotection in Parkinson's disease. In: Bar, PR and Beal, MF, (eds.) Neuroprotection in CNS diseases. (425 - 445). Marcel Dekker: New York.

Owen, AD and Schapira, AHV and Jenner, P and Marsden, CD (1997) Indices of oxidative stress in Parkinson's disease, Alzheimer's disease and dementia with Lewy bodies. J NEURAL TRANSM-SUPP (51) 167 - 173.

Rees, JH and Ginsberg, L and Schapira, AHV (1997) Two pregnant women with vomiting and fits. AM J OBSTET GYNECOL , 177 (6) 1539 - 1540.

Schapira, A (1997) Mitochondrial Mutations in Human Disease.

Schapira, AHV (1997) Mitochondrial disorders: An overview. J BIOENERG BIOMEMBR , 29 (2) 105 - 107.

Schapira, AHV (1997) Pathogenesis of Parkinson's disease. In: UNSPECIFIED (15 - 36). BAILLIERE TINDALL

Schapira, AHV (1997) Mitochondrial disorders. CURR OPIN NEUROL , 10 (1) 43 - 47.

Schapira, AHV (1997) Mitochondrial function in Huntington's disease: Clues for pathogenesis and prospects for treatment. ANN NEUROL , 41 (2) 141 - 142.

Schapira, AHV (1997) Future studies. In: Olanow, CW and Obeso, JA, (eds.) Beyond the decade of the brain. (233 - 238). Wells Medical: Kent.

Schapira, AHV (1997) Mitochondrial dysfunction and oxidative damage in Parkinson's disease. In: Beal, MF and Howell, N and Bodis-Wollner, I, (eds.) Mitochondrial and free radicals in neurodegenerative diseases. (343 - 358). John Wiley: New York.

Schapira, AHV and Warner, T and Gash, MT and Cleeter, MWJ and Marinho, CFM and Copper, JM (1997) Complex I function in familial and sporadic dystonia. ANN NEUROL , 41 (4) 556 - 559.

Seaton, TA and Cooper, JM and Schapira, AHV (1997) Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors. BRAIN RES , 777 (1-2) 110 - 118.

Silva, MT and Schapira, AHV and Jenner, P (1997) Unexpected findings of study of selegiline have not been treated with caution its authors advised. BRIT MED J , 315 (7104) 370 - 370.

Taanman, JW and Bodnar, AG and Cooper, JM and Morris, AAM and Clayton, PT and Leonard, JV and Schapira, AHV (1997) Molecular mechanisms in mitochondrial DNA depletion syndrome. HUM MOL GENET , 6 (6) 935 - 942.

Tabrizi, SJ and Cooper, JM and Xuereb, JH and Schapira, AHV (1997) Mechanisms involved in the pathogenesis of Huntington's disease. ANN NEUROL , 42 (3) T202 - T202.

Warner, TT and Schapira, AHV (1997) Genetic counselling in mitochondrial diseases. CURR OPIN NEUROL , 10 (5) 408 - 412.

Warner, TT and Schapira, AHV (1997) Mitochondrial dysfunction in neurodegeneration. Current Opinion in Neurology , 10 408 - 412.

1996

Chalmers, RM and Govan, GG and Schapira, AHV and Harding, AE (1996) HLA class I genotypes in Leber's hereditary optic neuropathy. J NEUROL SCI , 135 (2) 173 - 175.

Cooper, JM and Schapira, AH (1996) Biochemical investigation of mitochondrial respiratory chain abnormalities. In: Lane, R, (ed.) Hand Bood of Muscle Disease. (519 - ?). Marcel Dekker

Gu, M and Gash, MT and Mann, VM and JavoyAgid, F and Cooper, JM and Schapira, AHV (1996) Mitochondrial defect in Huntington's disease on caudate nucleus. ANN NEUROL , 39 (3) 385 - 389.

Owen, AD and Schapira, AHV and Jenner, P and Marsden, CD (1996) Oxidative stress and Parkinson's disease. PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS , 786 217 - 223.

Schapira, AHV (1996) Oxidative stress and mitochondrial dysfunction in neurodegeneration. CURR OPIN NEUROL , 9 (4) 260 - 264.

Schapira, AHV (1996) Neurotoxicity and the mechanisms of cell death in Parkinson's disease. PARKINSON'S DISEASE , 69 161 - 165.

Shergill, JK and Cammack, R and Cooper, CE and Cooper, JM and Mann, VM and Schapira, AHV (1996) Detection of nitrosyl complexes in human substantia nigra, in relation to Parkinson's disease. BIOCHEM BIOPH RES CO , 228 (2) 298 - 305.

Turner, LF and Kaddoura, S and Cooper, JM and Schapira, AHV and PooleWilson, PA (1996) Previously-reported mitochondrial DNA mutations are not a common cause of idiopathic dilated cardiomyopathy. HEART , 75 (5) 201 - 201.

1995

BODNAR, AG and COOPER, JM and LEONARD, JV and SCHAPIRA, AHV (1995) RESPIRATORY-DEFICIENT HUMAN FIBROBLASTS EXHIBITING DEFECTIVE MITOCHONDRIAL-DNA REPLICATION. BIOCHEM J , 305 817 - 822.

COCK, HR and COOPER, JM and SCHAPIRA, AHV (1995) THE 14484-ND6 MTDNA MUTATION IN LEBER HEREDITARY OPTIC NEUROPATHY DOES NOT AFFECT FIBROBLAST COMPLEX-I ACTIVITY. AM J HUM GENET , 57 (6) 1501 - 1502.

COCK, HR and COOPER, JM and SCHAPIRA, AHV (1995) NUCLEAR COMPLEMENTATION IN LEBER HEREDITARY OPTIC NEUROPATHY. NEUROLOGY , 45 (4) A294 - A294.

COOPER, JM and DANIEL, SE and MARSDEN, CD and SCHAPIRA, AHV (1995) L-DIHYDROXYPHENYLALANINE AND COMPLEX-I DEFICIENCY IN PARKINSONS-DISEASE BRAIN. MOVEMENT DISORD , 10 (3) 295 - 297.

MORGANHUGHES, JA and SWEENEY, MG and COOPER, JM and HAMMANS, SR and BROCKINGTON, M and SCHAPIRA, AHV and HARDING, AE and CLARK, JB (1995) MITOCHONDRIAL-DNA (MTDNA) DISEASES - CORRELATION OF GENOTYPE TO PHENOTYPE. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE , 1271 (1) 135 - 140.

Schapira, AH (1995) Nuclear and mitochondrial genetics in Parkinson's disease. J Med Genet , 32 (6) 411 - 414.

SCHAPIRA, AHV (1995) HARDING,ANITA - OBITUARY. BRIT MED J , 311 (7012) 1085 - 1085.

SCHAPIRA, AHV (1995) OXIDATIVE STRESS IN PARKINSONS-DISEASE. NEUROPATH APPL NEURO , 21 (1) 3 - 9.

SCHAPIRA, AHV (1995) Mitochondria, free radicals, neurodegeneration and aging. In: Cutler, RG and Packer, L and Bertram, J and Mori, A, (eds.) OXIDATIVE STRESS AND AGING. (pp. 159 - 169). BIRKHAUSER VERLAG

Schapira, AHV (1995) The role of mitochondrial dysfunction in neurodegenerative disease. In: Esser, K and Martin, GM, (eds.) MOLECULAR ASPECTS OF AGING. (pp. 241 - 251). JOHN WILEY & SONS LTD

SCHAPIRA, AHV and REICHMANN, H (1995) ELECTRON-TRANSPORT CHAIN DEFECTS IN ALZHEIMERS-DISEASE. NEUROLOGY , 45 (3) 599 - 600.

SMITH, PR and COOPER, JM and GOVAN, GG and RIORDANEVA, P and HARDING, AE and SCHAPIRA, AHV (1995) ANTIBODIES TO HUMAN OPTIC-NERVE IN LEBERS HEREDITARY OPTIC NEUROPATHY. J NEUROL SCI , 130 (2) 134 - 138.

1994

CLEETER, MWJ and COOPER, JM and DARLEYUSMAR, VM and MONCADA, S and SCHAPIRA, AHV (1994) REVERSIBLE INHIBITION OF CYTOCHROME-C-OXIDASE, THE TERMINAL ENZYME OF THE MITOCHONDRIAL RESPIRATORY-CHAIN, BY NITRIC-OXIDE - IMPLICATIONS FOR NEURODEGENERATIVE DISEASES. FEBS LETT , 345 (1) 50 - 54.

Cooper, JM and Clark, JB (1994) Abnormalities of mitochondrial respiratory chain complexes I-III in humans. In: Darley-Usmar, V and Schapira, AH, (eds.) UNSPECIFIED Portland Press

Cooper, JM and Clarke, JB (1994) The structural organisaton of the mitochondrial respiratory chain. In: Mitochondrial Disorders in Neurology. (1 - 30). Butterworth-Heinemann

DEXTER, DT and SIAN, J and ROSE, S and HINDMARSH, JG and MANN, VM and COOPER, JM and WELLS, FR and DANIEL, SE and LEES, AJ and SCHAPIRA, AHV and JENNER, P and MARSEN, CD (1994) INDEXES OF OXIDATIVE STRESS AND MITOCHONDRIAL-FUNCTION IN INDIVIDUALS WITH INCIDENTAL LEWY BODY DISEASE. ANN NEUROL , 35 (1) 38 - 44.

GOVAN, GG and SMITH, PR and KELLARWOOD, H and SCHAPIRA, AHV and HARDING, AE (1994) HLA CLASS-II GENOTYPES IN LEBERS HEREDITARY OPTIC NEUROPATHY. J NEUROL SCI , 126 (2) 193 - 196.

HARTLEY, A and STONE, JM and HERON, C and COOPER, JM and SCHAPIRA, AHV (1994) COMPLEX-I INHIBITORS INDUCE DOSE-DEPENDENT APOPTOSIS IN PC12 CELLS - RELEVANCE TO PARKINSONS-DISEASE. J NEUROCHEM , 63 (5) 1987 - 1990.

MANN, VM and COOPER, JM and DANIEL, SE and SRAI, K and JENNER, P and MARSDEN, CD and SCHAPIRA, AHV (1994) COMPLEX-I, IRON, AND FERRITIN IN PARKINSONS-DISEASE SUBSTANTIA-NIGRA. ANN NEUROL , 36 (6) 876 - 881.

Schapira, AH and Cooper, JM (1994) Biochemical and molecular features of deficiencies of complex I,II and III. In: Schapira, AHD and S,, (eds.) UNSPECIFIED (75 - 90). Butterworth-Heinemann

SCHAPIRA, AHV (1994) MITOCHONDRIAL-FUNCTION AND NEUROTOXICITY. CURR OPIN NEUROL , 7 (6) 531 - 534.

SCHAPIRA, AHV (1994) SCHAPIRA,MARKUS - OBITUARY. BRIT MED J , 309 (6962) 1155 - 1155.

SCHAPIRA, AHV (1994) ADVANCES IN THE UNDERSTANDING OF THE CAUSE OF PARKINSONS-DISEASE. J ROY SOC MED , 87 (7) 373 - 375.

SCHAPIRA, AHV (1994) EVIDENCE FOR MITOCHONDRIAL DYSFUNCTION IN PARKINSONS-DISEASE - A CRITICAL-APPRAISAL. MOVEMENT DISORD , 9 (2) 125 - 138.

SCHAPIRA, AHV and COOPER, JM (1994) INBORN AND INDUCED DEFECTS OF THE MITOCHONDRIAL RESPIRATORY-CHAIN. BIOCHEMICAL SOCIETY TRANSACTIONS , 22 (4) 996 - 1001.

SCHAPIRA, AHV and MARSDEN, CD (1994) BRITISH NEUROLOGY - A NATIONAL FOCUS. J NEUROL NEUROSUR PS , 57 (9) 1136 - 1136.

SCHAPIRA, AHV and MARSDEN, CD (1994) PLATELET MITOCHONDRIAL-DNA IN PARKINSONS-DISEASE. MOVEMENT DISORD , 9 (1) 119 - 120.

SMITH, PR and COOPER, JM and GOVAN, GG and HARDING, AE and SCHAPIRA, AHV (1994) PLATELET MITOCHONDRIAL-FUNCTION IN LEBERS HEREDITARY OPTIC NEUROPATHY. J NEUROL SCI , 122 (1) 80 - 83.

SWEENEY, MG and HAMMANS, SR and DUCHEN, LW and COOPER, JM and SCHAPIRA, AHV and KENNEDY, CR and JACOBS, JM and YOUL, BD and MORGANHUGHES, JA and HARDING, AE (1994) MITOCHONDRIAL-DNA MUTATION UNDERLYING LEIGHS SYNDROME - CLINICAL, PATHOLOGICAL, BIOCHEMICAL, AND GENETIC-STUDIES OF A PATIENT PRESENTING WITH PROGRESSIVE MYOCLONIC EPILEPSY. J NEUROL SCI , 121 (1) 57 - 65.

TAYLOR, DJ and KRIGE, D and BARNES, PRJ and KEMP, GJ and CARROLL, MT and MANN, VM and COOPER, JM and MARSDEN, CD and SCHAPIRA, AHV (1994) A P-31 MAGNETIC-RESONANCE SPECTROSCOPY STUDY OF MITOCHONDRIAL-FUNCTION IN SKELETAL-MUSCLE OF PATIENTS WITH PARKINSONS-DISEASE. J NEUROL SCI , 125 (1) 77 - 81.

1993

BODNAR, AG and COOPER, JM and HOLT, IJ and LEONARD, JV and SCHAPIRA, AHV (1993) NUCLEAR COMPLEMENTATION RESTORES MTDNA LEVELS IN CULTURED-CELLS FROM A PATIENT WITH MTDNA DEPLETION. AM J HUM GENET , 53 (3) 663 - 669.

BODNAR, AG and COOPER, JM and HOLT, IJ and LEONARD, JV and SCHAPIRA, AHV (1993) NUCLEAR COMPLEMENTATION OF MITOCHONDRIAL-DNA DEPLETION SYNDROME. ANN NEUROL , 34 (2) 305 - 305.

BODNAR, AG and COOPER, JM and MORGANHUGHES, JA and SCHAPIRA, AHV (1993) MITOCHONDRIAL MYOPATHY WITH A DEFECT IN MITOCHONDRIAL PROTEIN IMPORT. NEUROLOGY , 43 (4) A372 - A372.

COOPER, JM and WISCHIK, C and SCHAPIRA, AHV (1993) MITOCHONDRIAL-FUNCTION IN ALZHEIMERS-DISEASE. LANCET , 341 (8850) 969 - 970.

HARTLEY, A and COOPER, JM and SCHAPIRA, AHV (1993) IRON-INDUCED OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION - RELEVANCE TO PARKINSON DISEASE. BRAIN RES , 627 (2) 349 - 353.

Schapira, AH (1993) Mitochondrial cytopathies. Curr Opin Neurobiol , 3 (5) 760 - 767.

Schapira, AH (1993) Mitochondrial disorders. Curr Opin Genet Dev , 3 (3) 457 - 465.

SCHAPIRA, AHV (1993) THE USE OF TOXINS TO ELUCIDATE NEURAL FUNCTION AND DISEASE. CURR OPIN NEUROL NEU , 6 (3) 448 - 451.

SCHAPIRA, AHV (1993) MITOCHONDRIAL COMPLEX-I DEFICIENCY IN PARKINSONS-DISEASE. In: Narabayashi, H and Nagatsu, T and Yanagisawa, N and Mizuno, Y, (eds.) PARKINSONS DISEASE : FROM BASIC RESEARCH TO TREATMENT. (pp. 288 - 291). RAVEN PRESS

SCHAPIRA, AHV and HARTLEY, A and CLEETER, MWJ and COOPER, JM (1993) FREE-RADICALS AND MITOCHONDRIAL DYSFUNCTION IN PARKINSONS-DISEASE. BIOCHEMICAL SOCIETY TRANSACTIONS , 21 (2) 367 - 370.

SMALL, JR and THOMAS, PK and SCHAPIRA, AHV (1993) DORSAL-ROOT GANGLION PROTEINS IN FRIEDREICHS ATAXIA. NEUROSCI LETT , 163 (2) 182 - 184.

SMITH, PR and COOPER, JM and GOVAN, GG and HARDING, AE and SCHAPIRA, AHV (1993) SMOKING AND MITOCHONDRIAL-FUNCTION - A MODEL FOR ENVIRONMENTAL TOXINS. Q J MED , 86 (10) 657 - 660.

STEIGER, MJ and TARNESBY, G and GABE, S and MCLAUGHLIN, J and SCHAPIRA, AHV (1993) SUCCESSFUL OUTCOME OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY WITH CYTARABINE AND INTERFERON. ANN NEUROL , 33 (4) 407 - 411.

THOMAS, PK and COOPER, JM and KING, RHM and WORKMAN, JM and SCHAPIRA, AHV and GOSSSAMPSON, MA and MULLER, DPR (1993) MYOPATHY IN VITAMIN-E-DEFICIENT RATS - MUSCLE-FIBER NECROSIS ASSOCIATED WITH DISTURBANCES OF MITOCHONDRIAL-FUNCTION. J ANAT , 183 451 - 461.

1992

CLEETER, MWJ and COOPER, JM and SCHAPIRA, AHV (1992) IRREVERSIBLE INHIBITION OF MITOCHONDRIAL COMPLEX-I BY 1-METHYL-4-PHENYLPYRIDINIUM - EVIDENCE FOR FREE-RADICAL INVOLVEMENT. J NEUROCHEM , 58 (2) 786 - 789.

COOPER, JM and MANN, VM and KRIGE, D and SCHAPIRA, AHV (1992) HUMAN MITOCHONDRIAL COMPLEX-I DYSFUNCTION. BIOCHIMICA ET BIOPHYSICA ACTA , 1101 (2) 198 - 203.

COOPER, JM and MANN, VM and SCHAPIRA, AHV (1992) ANALYSES OF MITOCHONDRIAL RESPIRATORY-CHAIN FUNCTION AND MITOCHONDRIAL-DNA DELETION IN HUMAN SKELETAL-MUSCLE - EFFECT OF AGING. J NEUROL SCI , 113 (1) 91 - 98.

Dexter, DT and Jenner, P and Schapira, AH and Marsden, CD (1992) Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol , 32 Suppl S94 - 100.

DEXTER, DT and JENNER, P and SCHAPIRA, AHV and MARSDEN, CD (1992) ALTERATIONS IN LEVELS OF IRON, FERRITIN, AND OTHER TRACE-METALS IN NEURODEGENERATIVE DISEASES AFFECTING THE BASAL GANGLIA. In: ANNALS OF NEUROLOGY. (pp. S94 - S100). LITTLE BROWN CO

HAINES, AMR and COOPER, JM and MORGANHUGHES, JA and CLARK, JB and SCHAPIRA, AHV (1992) ONE-STEP IMMUNOAFFINITY PURIFICATION OF COMPLEX-I SUBUNITS FROM BEEF-HEART MITOCHONDRIA. PROTEIN EXPRES PURIF , 3 (3) 223 - 227.

Jenner, P and Dexter, DT and Sian, J and Schapira, AH and Marsden, CD (1992) Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol , 32 Suppl S82 - S87.

JENNER, P and DEXTER, DT and SIAN, J and SCHAPIRA, AHV and MARSDEN, CD (1992) OXIDATIVE STRESS AS A CAUSE OF NIGRAL CELL-DEATH IN PARKINSONS-DISEASE AND INCIDENTAL LEWY BODY DISEASE. In: ANNALS OF NEUROLOGY. (pp. S82 - S87). LITTLE BROWN CO

JENNER, P and SCHAPIRA, AHV and MARSDEN, CD (1992) NEW INSIGHTS INTO THE CAUSE OF PARKINSONS-DISEASE. NEUROLOGY , 42 (12) 2241 - 2250.

Krige, D and Carroll, MT and Cooper, JM and Marsden, CD and Schapira, AH (1992) Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group. Ann Neurol , 32 (6) 782 - 788. 10.1002/ana.410320612.

KRIGE, D and CARROLL, MT and COOPER, JM and MARSDEN, CD and SCHAPIRA, AHV (1992) PLATELET MITOCHONDRIAL-FUNCTION IN PARKINSONS-DISEASE. ANN NEUROL , 32 (6) 782 - 788.

MANN, VM and COOPER, JM and KRIGE, D and DANIEL, SE and SCHAPIRA, AHV and MARSDEN, CD (1992) BRAIN, SKELETAL-MUSCLE AND PLATELET HOMOGENATE MITOCHONDRIAL-FUNCTION IN PARKINSONS-DISEASE. BRAIN , 115 333 - 342.

MANN, VM and COOPER, JM and SCHAPIRA, AHV (1992) QUANTITATION OF A MITOCHONDRIAL-DNA DELETION IN PARKINSONS-DISEASE. FEBS LETT , 299 (3) 218 - 222.

Schapira, AH (1992) Colloidal gold staining and immunodetection in 2-d protein mapping. Methods Mol Biol , 10 255 - 259. 10.1385/0-89603-204-3:255.

Schapira, AH (1992) Colloidal gold staining and immunodetection in 2-d protein mapping. Methods Mol Biol , 80 255 - 259. 10.1385/0-89603-204-3:255.

Schapira, AH and Mann, VM and Cooper, JM and Krige, D and Jenner, PJ and Marsden, CD (1992) Mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol , 32 Suppl S116 - S124.

SCHAPIRA, AHV (1992) MPTP AND OTHER PARKINSON-INDUCING AGENTS. CURR OPIN NEUROL NEU , 5 (3) 396 - 400.

SCHAPIRA, AHV and COOPER, JM (1992) MITOCHONDRIAL-FUNCTION IN NEURODEGENERATION AND AGING. MUTAT RES , 275 (3-6) 133 - 143.

SCHAPIRA, AHV and MANN, VM and COOPER, JM and KRIGE, D and JENNER, PJ and MARSDEN, CD (1992) MITOCHONDRIAL-FUNCTION IN PARKINSONS-DISEASE. In: ANNALS OF NEUROLOGY. (pp. S116 - S124). LITTLE BROWN CO

SMITH, CAD and GOUGH, AC and LEIGH, PN and SUMMERS, BA and HARDING, AE and MARANGANORE, DM and STURMAN, SG and SCHAPIRA, AHV and WILLIAMS, AC and SPURR, NK and WOLF, CR (1992) DEBRISOQUINE HYDROXYLASE GENE POLYMORPHISM AND SUSCEPTIBILITY TO PARKINSONS-DISEASE. LANCET , 339 (8806) 1375 - 1377.

1991

GALE, AN and GIBBS, JM and SCHAPIRA, AHV and THOMAS, PK (1991) NEUROLOGY. POSTGRAD MED J , 67 (788) 509 - 531.

MORGANHUGHES, JA and COOPER, JM and SCHAPIRA, AHV and SWEENY, M and HOLT, IJ and HARDING, AE and CLARK, JB (1991) THE MOLECULAR PATHOLOGY OF HUMAN RESPIRATORY-CHAIN DEFECTS. REV NEUROL , 147 (6-7) 450 - 454.

SCHAPIRA, AHV (1991) MITOCHONDRIAL NADH UBIQUINONE REDUCTASE DEFICIENCY IN PARKINSONS-DISEASE. BIOL CHEM H-S , 372 (8) 552 - 553.

1990

BET, L and BRESOLIN, N and MOGGIO, M and MEOLA, G and PRELLE, A and SCHAPIRA, AH and BINZONI, T and CHOMYN, A and FORTUNATO, F and CERRETELLI, P and SCARLATO, G (1990) A CASE OF MITOCHONDRIAL MYOPATHY, LACTIC-ACIDOSIS AND COMPLEX-I DEFICIENCY. J NEUROL , 237 (7) 399 - 404.

COOPER, JM and SCHAPIRA, AHV and HOLT, IJ and TOSCANO, A and HARDING, AE and MORGANHUGHES, JA and CLARK, JB (1990) BIOCHEMICAL AND MOLECULAR ASPECTS OF HUMAN MITOCHONDRIAL RESPIRATORY-CHAIN DISORDERS. BIOCHEMICAL SOCIETY TRANSACTIONS , 18 (4) 517 - 519.

HARDING, AE and HOLT, IJ and COOPER, JM and SCHAPIRA, AHV and SWEENEY, M and CLARK, JB and MORGANHUGHES, JA (1990) MITOCHONDRIAL MYOPATHIES - GENETIC-DEFECTS. BIOCHEMICAL SOCIETY TRANSACTIONS , 18 (4) 519 - 522.

MANN, VM and COOPER, JM and JAVOYAGID, F and AGID, Y and JENNER, P and SCHAPIRA, AHV (1990) MITOCHONDRIAL-FUNCTION AND PARENTAL SEX EFFECT IN HUNTINGTONS-DISEASE. LANCET , 336 (8717) 749 - 749.

MORGANHUGHES, JA and COOPER, JM and HOLT, IJ and HARDING, AE and SCHAPIRA, AHV and CLARK, JB (1990) MITOCHONDRIAL MYOPATHIES - CLINICAL DEFECTS. BIOCHEMICAL SOCIETY TRANSACTIONS , 18 (4) 523 - 526.

MORGANHUGHES, JA and SCHAPIRA, AHV and COOPER, JM and HOLT, IJ and HARDING, AE and CLARK, JB (1990) THE MOLECULAR PATHOLOGY OF RESPIRATORY-CHAIN DYSFUNCTION IN HUMAN MITOCHONDRIAL MYOPATHIES. BIOCHIM BIOPHYS ACTA , 1018 (2-3) 217 - 222.

SCHAPIRA, AHV (1990) MITOCHONDRIAL DISORDERS. CURR OPIN NEUROL NEU , 3 (3) 425 - 430.

SCHAPIRA, AHV and COOPER, JM and DEXTER, D and CLARK, JB and JENNER, P and MARSDEN, CD (1990) MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSONS-DISEASE. J NEUROCHEM , 54 (3) 823 - 827.

SCHAPIRA, AHV and COOPER, JM and MANNESCHI, L and VITAL, C and MORGANHUGHES, JA and CLARK, JB (1990) A MITOCHONDRIAL ENCEPHALOMYOPATHY WITH SPECIFIC DEFICIENCIES OF 2 RESPIRATORY-CHAIN POLYPEPTIDES AND A CIRCULATING AUTOANTIBODY TO A MITOCHONDRIAL MATRIX PROTEIN. BRAIN , 113 419 - 432.

SCHAPIRA, AHV and COOPER, JM and MORGANHUGHES, JA and LANDON, DN and CLARK, JB (1990) MITOCHONDRIAL MYOPATHY WITH A DEFECT OF MITOCHONDRIAL-PROTEIN TRANSPORT. NEW ENGL J MED , 323 (1) 37 - 42.

SCHAPIRA, AHV and HOLT, IJ and SWEENEY, M and HARDING, AE and JENNER, P and MARSDEN, CD (1990) MITOCHONDRIAL-DNA ANALYSIS IN PARKINSONS-DISEASE. MOVEMENT DISORD , 5 (4) 294 - 297.

SCHAPIRA, AHV and MANN, VM and COOPER, JM and DEXTER, D and DANIEL, SE and JENNER, P and CLARK, JB and MARSDEN, CD (1990) ANATOMIC AND DISEASE SPECIFICITY OF NADH COQ1 REDUCTASE (COMPLEX-I) DEFICIENCY IN PARKINSONS-DISEASE. J NEUROCHEM , 55 (6) 2142 - 2145.

1989

HOLT, IJ and HARDING, AE and COOPER, JM and SCHAPIRA, AHV and TOSCANO, A and CLARK, JB and MORGANHUGHES, JA (1989) MITOCHONDRIAL MYOPATHIES - CLINICAL AND BIOCHEMICAL FEATURES OF 30 PATIENTS WITH MAJOR DELETIONS OF MUSCLE MITOCHONDRIAL-DNA. ANN NEUROL , 26 (6) 699 - 708.

Schapira, AH (1989) Mitochondrial myopathies. BMJ , 298 (6681) 1127 - 1128.

SCHAPIRA, AHV (1989) MITOCHONDRIAL MYOPATHIES - MECHANISMS NOW BETTER UNDERSTOOD. BRIT MED J , 298 (6681) 1127 - 1128.

SCHAPIRA, AHV and COOPER, JM and DEXTER, D and CLARK, JB and JENNER, P and MARSDEN, CD (1989) MITOCHONDRIAL COMPLEX-I DEFICIENCY IN PARKINSONS-DISEASE. ANN NEUROL , 26 (1) 122 - 122.

SCHAPIRA, AHV and COOPER, JM and DEXTER, D and JENNER, P and CLARK, JB and MARSDEN, CD (1989) MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSONS-DISEASE. LANCET , 1 (8649) 1269 - 1269.

SCHAPIRA, AHV and LLEWELYN, JG and PATEL, NJ and THOMAS, PK (1989) POLYPEPTIDE AND GLYCOPROTEIN ABNORMALITIES IN DORSAL-ROOT GANGLIA OF STREPTOZOTOCIN-DIABETIC RATS. J NEUROL SCI , 94 (1-3) 147 - 161.

1988

MORGANHUGHES, JA and SCHAPIRA, AHV and COOPER, JM and CLARK, JB (1988) MOLECULAR DEFECTS OF NADH-UBIQUINONE OXIDOREDUCTASE (COMPLEX-I) IN MITOCHONDRIAL DISEASES. J BIOENERG BIOMEMBR , 20 (3) 365 - 382.

MORGANHUGHES, JA and SCHAPIRA, AHV and COOPER, JM and HAYES, DJ and CLARK, JB (1988) HUMAN MITOCHONDRIAL RESPIRATORY-CHAIN DEFICIENCIES. AUST PAEDIATR J , 24 55 - 57.

SCHAPIRA, AHV and KEIR, G (1988) TWO-DIMENSIONAL PROTEIN MAPPING BY GOLD STAIN AND IMMUNOBLOTTING. ANAL BIOCHEM , 169 (1) 167 - 171.

SCHAPIRA, AHV and MORGANHUGHES, JA and CLEETER, MJW and COOPER, JM and PATEL, SD and RAGAN, CI and CLARK, JB (1988) MOLECULAR-BASIS OF MITOCHONDRIAL MYOPATHIES - POLYPEPTIDE ANALYSIS IN COMPLEX-I DEFICIENCY. LANCET , 1 (8584) 500 - 503.

1987

Morgan-Hughes, JA and Cooper, JM and Schapira, AH and Hayes, DJ and Clark, JB (1987) The mitochondrial myopathies. Defects of the mitochondrial respiratory chain and oxidative phosphorylation system. Electroencephalogr Clin Neurophysiol Suppl , 39 103 - 114.

SCHAPIRA, AHV and COOPER, JM and MORGANHUGHES, JA and LANDON, DN (1987) A MITOCHONDRIAL MYOPATHY WITH SPECIFIC DEFICIENCIES OF SUCCINIC-DEHYDROGENASE ACTIVITY AND THE RIESKE IRON SULFUR PROTEIN OF COMPLEX-III. NEUROPATH APPL NEURO , 13 (6) 497 - 497.

1986

MORGANHUGHES, JA and COOPER, JM and SCHAPIRA, AHV and CLARK, JB (1986) MITOCHONDRIAL MYOPATHIES. MUSCLE NERVE , 9 (5) 78 - 78.

Schapira, AH and Thomas, PK (1986) A case of recurrent idiopathic ophthalmoplegic neuropathy (Miller Fisher syndrome). J Neurol Neurosurg Psychiatry , 49 (4) 463 - 464.

SCHAPIRA, AHV and COOPER, JM and MORGANHUGHES, JA and CLARK, JB (1986) EVIDENCE FOR MOLECULAR HETEROGENEITY IN HUMAN COMPLEX-I DEFICIENCY. MUSCLE NERVE , 9 (5) 183 - 183.

1985

SCHAPIRA, AHV and GALE, AN (1985) PSEUDOMONAS OSTEITIS CAUSING CRANIAL NERVE PALSIES. J NEUROL NEUROSUR PS , 48 (12) 1306 - 1307.

SCHAPIRA, AHV and HUTTON, RA (1985) PLATELET-AGGREGATION IN MYOTONIA. J NEUROL SCI , 71 (2-3) 351 - 357.

1981

Schapira, AH (1981) Myasthenia gravis: a case report. Age Ageing , 10 (3) 198 - 199.

SCHAPIRA, AHV (1981) HOW DOES LIGNOCAINE PREVENT VENTRICULAR-FIBRILLATION. LANCET , 2 (8256) 1167 - 1168.

1980

BAKER, PF and SCHAPIRA, AHV (1980) ANESTHETICS INCREASE LIGHT-EMISSION FROM AEQUORIN AT CONSTANT IONIZED CALCIUM. NATURE , 284 (5752) 168 - 169.

SCHAPIRA, AHV and DYSON, PHP (1980) VANCOMYCIN DOSE FOR PSEUDOMEMBRANOUS COLITIS. LANCET , 2 (8187) 204 - 204.

1977

BAKER, PF and SCHAPIRA, AHV (1977) MEASUREMENT OF IONIC-DIFFUSION AND MOBILITY IN AXOPLASM ISOLATED FROM AXONS OF MYXICOLA. J PHYSIOL-LONDON , 266 (1) P5 - P5.

NULL

Blamire, AM and Cooke, F and Manners, DN and Korlipara, LVP and Styles, P and Schapira, AHV and Rajagopalan, B and Cooper, JM MRS measurement of neuronal dysfunction in the CNS in Friedreich's Ataxia and relationship to disability. Archives of Neurology

This list was generated on Tue May 21 07:03:52 2013 BST.

Page last modified on 20 mar 13 17:22