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John Hardy, PhD, right, accepted the 2015 Robert A. Pritzker Prize from MJFF VP Brian Fiske, PhD, and Michael J. Fox on April 15.

John Hardy awarded 2015 Robert A. Pritzker Prize for Leadership in Parkinson's Research

One of the UK Parkinson's Disease Consortium Principal Investigators, Prof John Hardy, has been awarded the 2015 Robert A. Pritzker Prize for his leadership in Parkinson's genetics research. The award was presented by Michael J. Fox at a ceremony in New York on April 15. From the Michael J. Fox Foundation website: More...

Webcast - Prof Nicholas Wood - Advances in Genetic Understanding of Parkinson's Disease.

Video: Advances in Genetic Understanding of Parkinson's Disease

Webcast of the presentation entitled ‘Advances in Genetic Understanding of Parkinson's Disease’ given by Nicholas Wood (University College London, United Kingdom) presented at the Biochemical Society Hot Topic event, PINK1-Parkin Signalling in Parkinson’s Disease and Beyond, held in December 2014. More...

Pedigrees and I-FP-CIT SPECT scan images of the four families with GCH1 mutations involved in this study.

GCH1 gene and Parkinson's risk

A study published in Brain, led by researchers at UCL Institute of Neurology, has shown that genetic mutations which cause a decrease in dopamine production in the brain and lead to a form of childhood-onset Dystonia, also play a role in the development of Parkinson’s disease.

Leonard Wolfson Experimental Neurology Centre (LWENC)

The new Leonard Wolfson Experimental Neurology Centre (LWENC) has opened for clinical studies and trials


Audioslide presentation on Claudia Manzoni's paper examining how fibroblasts with LRRK2 mutations react to starvation conditions and the possible deficits that they have in autophagy.

LRRK2 and autophagy in fibroblasts

In this paper Claudia Manzoni studies how fibroblast cells from people with Parkinson’s disease caused by mutations in LRRK2 react to starvation. Although the changes are quite subtle, there are differences between the way that fibroblasts that contain mutant LRRK2 respond to being starved – suggesting that there may be changes in the way that these cells regulate a key process called autophagy (a term which comes from the greek meaning to eat yourself, and is one of the ways that cells get rid of waste and recycle proteins and organellles).

Video: Parkinson's and the Genetic Revolution: From Genes to Treatments

17 June 2013

Dr Patrick Lewis of University College London and Dr Flaviano Giorgini of the University of Leicester, discuss how their work on genetics is helping us develop treatments for Parkinson's.

The last ten years have seen a revolution in our understanding of genetics, demonstrated by the truly monumental sequencing of the human genome. This has, in turn, had a massive impact on the way in which we approach the research of human conditions -- including Parkinson's.

Poster: Parkinson's and the Genetic Revolution: From Genes to Treatments

We now know that there are many genes that are linked to Parkinson's, and much of the research into this condition over the past decade has attempted to bridge the gap between identifying these genes and figuring out why they cause nerve cells to die.

In this lecture, we will take you on a journey through the genetics of Parkinson's. We talk about how we as scientists are using genetics to learn about the causes of the condition -- providing us with new potential targets in the hunt for better treatments.

The Gretschen Amphlet Memorial Lecture 2013. Film footage of the lecture and Q&A taken at Fitzwilliam College Cambridge on the 17 April 2013.

Page last modified on 17 jun 13 10:15