UK Parkinson's Disease Consortium - UKPDC
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- Degenerating neurons
- Department of Molecular Neuroscience, UCL
- Department of Clinical Neuroscience, UCL
- MRC Protein Phosphorylation Unit, Dundee
- MRC Centre for Developmental and Biomedical Genetics, Sheffield
- Eisai Ltd
- Clinical Movement Disorders Group, UCL
- MRC Centre for Neuromuscular Diseases, UCL
- Neurodegeneration, UCL
- Neurophysiology of Human Development, UCL
- Pathophysiology of Human Movement Disorders, UCL
- Queen Square Brain Bank, UCL
- Reta Lila Weston Institute of Neurological Studies, UCL
- Sobell Department of Motor Neuroscience and Movement Disorders, UCL
- Unit of Functional Neurosurgery, UCL
- UCL Consortium for Mitochondrial Research
- UCL Genetics Institute (UGI)
- UCL Genomics
- Neurogenetics Unit, UCLH
- Neurometabolic Unit, UCLH
- Lysosomal Storage Disorders Unit, Royal Free
- School of Medicine and Dentistry, Aberdeen
- PD Med, Birmingham
- Cambridge Bristol Toronto Hamburg Neurodegenerative Disease Consortium
- Cambridge Centre for Brain Repair
- The Movement Disorders Group, Cambridge
- MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff
- MRC Centre for Regenerative Medicine, Edinburgh
- MRC Sudden Death Brain and Tissue Bank, Edinburgh
- The Institute of Cancer Research
- Bioinformatics, Statistical Genetics & Epigenetics, KCL
- MRC Toxicology Unit, Leicester
- Wellcome Trust Case Control Consortium
- WT/MRC Neurodegenarative Diseases Initiative
- Wellcome Trust Sanger Institute
- AMC Department of Neurology, Amsterdam
- Department of Clinical Genetics, VUMC
- Laboratory of Neurogenetics, NIA/NIH
- French National Institute of Health and Medical Research (Inserm)
- Brain & Spine Institute, Paris
- Centre-de-Physiopathologie-de-Toulouse-Purpan (CPTP)
- Department for Neurodegenerative Diseases, Tübingen
- Funding
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News
Public lecture: The autophagy signaling network, c-‐myc and pathology: don't mess with the cell cycle!
You are invited to a public lecture by Francesco Cecconi, an eminent scientist in the field of autophagy and neurodegeneration, on Thursday the 25th of April at 17:00, in the lecture theatre of 33 Queen Square, University College Hospital London, WC1N. The lecture will be followed by a general discussion with drinks and food. More...
Video: Brain Disease Research - Keeping You You
Have you ever wondered how scientists research the brain?
Have you wondered who digs through that beautiful mass of grey matter between
our ears to understand how it works and why it stops working? Meet the
Neurodegenerative Diseases Initiative. Funded by the Wellcome Trust and MRC, this
team of scientists from around the globe investigates Alzheimer's, Parkinson's
and Motor Neuron Diseases. The team is on the hunt for understanding and
treatments for brain diseases. More...
Video: Degenerating Brains public symposium
The "Degenerating Brains" public symposium was held on the 13th March 2013, as part of Brain Awareness Week. Around 250 people showed up to hear Professors John Hardy (UCL), Chris Shaw (KCL) and David Rubinsztein (Cambridge) discuss new discoveries in neurodegenerative diseases and how they might impact drug treatment. More...
Mutations in VCP gene implicated in a number of neurodegenerative diseases
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget’s Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS). More...
Public lectures: new research into Alzheimer's, Parkinson's and Motor Neuron Disease
You are invited to an evening (13th March 2013) exploring the very latest in cutting edge research into neurodegenerative diseases. Supported by the Wellcome Trust, scientists investigating Alzheimer's, Parkinson's and Motor Neuron disease will explain how our understanding of these disorders is changing in the light of new discoveries in genetics and cell biology, and how these discoveries impact on developing new drugs for these diseases.
18.00 Welcome and introduction
18.10 Lectures commence
More...
Bioinformatics, Statistical Genetics & Epigenetics, KCL
The Bioinformatics, Statistical Genetics & Epigenetics (BSGE), King's College London (KCL), cluster combines an interdisciplinary research programme drawing from
expertise across a group of investigators working towards interpreting
genetics and genomes in medicine and biology.
The Bioinformatics
component develops and applies methodologies and applications across a
broad spectrum of genetics-related data analysis tools including next
generation sequencing (NGS) analysis, microarray analysis, evolutionary
biology and interaction networks especially as they relate to disease
processes.
The Statistical Genetics component focuses on
inferential techniques for drawing appropriate conclusions from noisy
data, and applications include genome-wide association studies (GWAS) as
well as aspects of NGS.
The Epigenetics component focuses on
understanding the mechanisms of this important mode of gene regulation,
and how the misplacement or misinterpretation of epigenetic marks can
contribute to human disease states. This is achieved through combining
molecular biology with powerful bioinformatics approaches, enabling data
from the laboratory to be extrapolated to the whole genome
Together,
these three disciplines provide a powerful genetic analysis programme
to assess human variation, disease aetiology and the contribution of
epigenetics in inherited disease.
Page last modified on 18 mar 11 15:57
