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Poster for Autophagy in London public lecture

Public lecture: The autophagy signaling network, c-­‐myc and pathology: don't mess with the cell cycle!

You are invited to a public lecture by Francesco Cecconi, an eminent scientist in the field of autophagy and neurodegeneration, on Thursday the 25th of April at 17:00, in the lecture theatre of 33 Queen Square, University College Hospital London, WC1N. The lecture will be followed by a general discussion with drinks and food. More...

Link to film: Brain Disease Research - Keeping You You

Video: Brain Disease Research - Keeping You You


Have you ever wondered how scientists research the brain? Have you wondered who digs through that beautiful mass of grey matter between our ears to understand how it works and why it stops working? Meet the Neurodegenerative Diseases Initiative. Funded by the Wellcome Trust and MRC, this team of scientists from around the globe investigates Alzheimer's, Parkinson's and Motor Neuron Diseases. The team is on the hunt for understanding and treatments for brain diseases. More...

Degenerating Brains public symposium - 13th March 2013

Video: Degenerating Brains public symposium


The "Degenerating Brains" public symposium was held on the 13th March 2013, as part of Brain Awareness Week. Around 250 people showed up to hear Professors John Hardy (UCL), Chris Shaw (KCL) and David Rubinsztein (Cambridge) discuss new discoveries in neurodegenerative diseases and how they might impact drug treatment. More...

Colour-enhanced image of a mitochondrion showing the internal membranes (cristae) and enzyme complexes. Credit Dr David Furness, Wellcome Images.

Mutations in VCP gene implicated in a number of neurodegenerative diseases

New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget’s Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS). More...

Poster for Degenerating brains: new research into Alzheimer's, Parkinson's and Motor Neuron Disease

Public lectures: new research into Alzheimer's, Parkinson's and Motor Neuron Disease

You are invited to an evening (13th March 2013) exploring the very latest in cutting edge research into neurodegenerative diseases. Supported by the Wellcome Trust, scientists investigating Alzheimer's, Parkinson's and Motor Neuron disease will explain how our understanding of these disorders is changing in the light of new discoveries in genetics and cell biology, and how these discoveries impact on developing new drugs for these diseases.

18.00 Welcome and introduction

18.10 Lectures commence

More...

Sobell Department of Motor Neuroscience and Movement Disorders, UCL

The Sobell Department of Motor Neuroscience and Movement Disorders at the UCL Institute of Neurology is in the unique position of pursuing research in basic neuroscience that is of direct translational benefit to neurological disorders such as Parkinson’s disease, dystonia, stroke, motor neurone disease, peripheral nerve disorders and spinal cord injury. Our Research Groups use a powerful combination of modern non-invasive research technology, theoretical and computational approaches and a variety of cellular, animal and human models to explore how the brain controls normal movement, and how disease leads to disordered control of movement.

Current clinical research programmes involve TMS, repetitive TMS, EEG, MEG, fMRI and structural MRI (VBM, DTI), while translational programmes include use of cell culture, molecular biology and transgenic approaches. We have a strong interest in the cognitive aspects of motor control, including brain mechanisms of decision making and response selection. This is supported by sophisticated neurophysiological techniques for the monitoring of large populations neurons in active brain networks. We have numerous collaborative scientific and clinical research links across the Institute of Neurology, UCL and particularly strong links with the National Hospital for Neurology and Neurosurgery.

The Department also includes the Unit of Functional Neurosurgery, which leads research and clinical treatment of Parkinson’s disease, dystonia and a number of other disorders using Deep Brain Stimulation (DBS) and recording.


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