UK Parkinson's Disease Consortium - UKPDC
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Prof John Hardy

Prof John Hardy is the first UK winner of $3m Breakthrough Prize in Life Sciences

Professor John Hardy (UCL Institute of Neurology) has been awarded the $3 million Breakthrough Prize in Life Sciences for his pioneering research into the genetic causes of Alzheimer’s disease, other forms of dementia and Parkinson’s disease. More...

John Hardy, PhD, right, accepted the 2015 Robert A. Pritzker Prize from MJFF VP Brian Fiske, PhD, and Michael J. Fox on April 15.

John Hardy awarded 2015 Robert A. Pritzker Prize for Leadership in Parkinson's Research

One of the UK Parkinson's Disease Consortium Principal Investigators, Prof John Hardy, has been awarded the 2015 Robert A. Pritzker Prize for his leadership in Parkinson's genetics research. The award was presented by Michael J. Fox at a ceremony in New York on April 15. From the Michael J. Fox Foundation website: More...

Webcast - Prof Nicholas Wood - Advances in Genetic Understanding of Parkinson's Disease.

Video: Advances in Genetic Understanding of Parkinson's Disease

Webcast of the presentation entitled ‘Advances in Genetic Understanding of Parkinson's Disease’ given by Nicholas Wood (University College London, United Kingdom) presented at the Biochemical Society Hot Topic event, PINK1-Parkin Signalling in Parkinson’s Disease and Beyond, held in December 2014. More...

Pedigrees and I-FP-CIT SPECT scan images of the four families with GCH1 mutations involved in this study.

GCH1 gene and Parkinson's risk

A study published in Brain, led by researchers at UCL Institute of Neurology, has shown that genetic mutations which cause a decrease in dopamine production in the brain and lead to a form of childhood-onset Dystonia, also play a role in the development of Parkinson’s disease.

Leonard Wolfson Experimental Neurology Centre (LWENC)

The new Leonard Wolfson Experimental Neurology Centre (LWENC) has opened for clinical studies and trials


Pathophysiology of Human Movement Disorders, UCL

Movement disorders cover a diverse range of neurological conditions from Parkinson’s disease to tremor and dystonia. They are thought of primarily as disorders of basal ganglia function, but the consequences of such dysfunction and the contribution of other brain areas are only beginning to be understood. Our current research has three broad aims: 1) To improve and develop clinical categorisation of movement disorders by researching electrophysiological “signatures” or biomarkers of particular disorders, 2) to use electrophysiological and psychophysical techniques to explore the pathophysiology of different movement disorders and 3) to research the possible application of rTMS in the treatment of movement disorders.

The Pathophysiology of Human Movement Disorders lab at the Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology is based in number 33 Queen Square with access to state of the art electrophysiology facilities.

We use the following techniques:

- Transcranial magnetic stimulation to measure various parameters of cortical excitability.

- Repetitive transcranial magnetic stimulation, paired associative stimulation to explore brain plasticity.


- Psychophysical assessments of reaction time, attention and learning.


Page last modified on 17 mar 11 11:12