UK Parkinson's Disease Consortium

UK Parkinson's Disease Consortium - UKPDC

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• Co-Investigators
  • Dario Alessi
  • Alex Whitworth
  • Andrey Abramov
  • Kailash Bhatia
  • J. Mark Cooper
  • Michael Duchen
  • Derralynn Hughes
  • Andrew Lees
  • Atul Mehta
  • Tamas Revesz
  • Jan-Willem Taanman
  • Tarek Yousry
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Michael Duchen

(Co-Investigator)

We are interested in a wide range of issues related to mitochondrial biology and cell signaling. Much of our current work is focused on interrelationships between calcium signaling, mitochondria and free radicals in cell physiology and pathophysiology. This work embraces questions about the contributions of mitochondrial function to intracellular calcium signaling; about the contributions of mitochondrial dysfunction to cell injury and cell death - by necrosis or apoptosis - in situations such as ischaemia, reperfusion injury.

As well as being a founding PI of the UK Parkinson's Disease Consortium, Prof Duchen is a founding PI of the MRC Centre for Neuromuscular Diseases and coordinator of the UCL Consortium for Mitochondrial research (UCL CfMR).

Contact details

Lab website

Link to publications

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Number of items: 254.

2013

Chlystun, M and Campanella, M and Law, AL and Duchen, MR and Fatimathas, L and Levine, TP and Gerke, V and Moss, SE (2013) Regulation of mitochondrial morphogenesis by annexin a6. PLoS One , 8 (1) , Article e53774 . 10.1371/journal.pone.0053774. An open access publication. A version is also available from UCL Discovery.

Corona, JC and Duchen, MR (2013) Rosiglitazone protects human neuron-like cells against complex I inhibition through improvement of mitochondrial function. In: JOURNAL OF NEUROCHEMISTRY. (pp. 177 - 178).

Faccenda, D and Tan, CH and Seraphim, A and Duchen, MR and Campanella, M (2013) IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ , 20 (5) 686 - 697. 10.1038/cdd.2012.163.

Osellame, LD and Rahim, AA and Hargreaves, IP and Gegg, ME and Richard-Londt, A and Brandner, S and Waddington, SN and Schapira, AH and Duchen, MR (2013) Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease-Links to Parkinson's Disease. Cell Metab 10.1016/j.cmet.2013.04.014.

2012

Abeti, R and Duchen, MR (2012) Activation of PARP by oxidative stress induced by β-amyloid: implications for Alzheimer's disease. Neurochem Res , 37 (11) 2589 - 2596. 10.1007/s11064-012-0895-x.

Corona, JC and Duchen, MR (2012) Rosiglitazone protects differentiated SH-SY5Y cells against damage induced by rotenone through mitochondrial biogenesis and by anti-oxidative mechanisms. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS , 1817 S68 - S68. 10.1016/j.bbabio.2012.06.192.

Davidson, SM and Duchen, MR (2012) Imaging mitochondrial calcium signalling with fluorescent probes and single or two photon confocal microscopy. Methods Mol Biol , 810 219 - 234. 10.1007/978-1-61779-382-0_14.

Davidson, SM and Yellon, DM and Murphy, MP and Duchen, MR (2012) Slow calcium waves and redox changes precede mitochondrial permeability transition pore opening in the intact heart during hypoxia and reoxygenation. Cardiovasc Res , 93 (3) 445 - 453. 10.1093/cvr/cvr349.

Ding, S and Riddoch-Contreras, J and Abramov, AY and Qi, Z and Duchen, MR (2012) Erratum to: Mild stress of caffeine increased mtDNA content in skeletal muscle cells: the interplay between Ca(2+) transients and nitric oxide. J Muscle Res Cell Motil , 33 (5) 339 - ?. 10.1007/s10974-012-9327-4.

Ding, S and Riddoch-Contreras, J and Abramov, AY and Qi, Z and Duchen, MR (2012) Mild stress of caffeine increased mtDNA content in skeletal muscle cells: the interplay between Ca2+ transients and nitric oxide. J Muscle Res Cell Motil , 33 (5) 327 - 337. 10.1007/s10974-012-9318-5.

Duchen, MR (2012) Mitochondria, calcium-dependent neuronal death and neurodegenerative disease. Pflugers Arch , 464 (1) 111 - 121. 10.1007/s00424-012-1112-0. An open access publication

Gandhi, S and Vaarmann, A and Yao, Z and Duchen, MR and Wood, NW and Abramov, AY (2012) Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease. PLoS One , 7 (5) , Article e37564 . 10.1371/journal.pone.0037564. An open access publication. A version is also available from UCL Discovery.

Girard, M and Larivière, R and Parfitt, DA and Deane, EC and Gaudet, R and Nossova, N and Blondeau, F and Prenosil, G and Vermeulen, EG and Duchen, MR and Richter, A and Shoubridge, EA and Gehring, K and McKinney, RA and Brais, B and Chapple, JP and McPherson, PS (2012) Mitochondrial dysfunction and Purkinje cell loss in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). Proc Natl Acad Sci U S A , 109 (5) 1661 - 1666. 10.1073/pnas.1113166109.

Munteanu, I and Zhou, H and Hargreaves, I and Yasukawa, T and Duchen, MR and Muntoni, F (2012) Investigating mitochondria in cell culture models of core myopathies. In: NEUROMUSCULAR DISORDERS. (pp. S30 - S30).

Osellame, LD and Blacker, TS and Duchen, MR (2012) Cellular and molecular mechanisms of mitochondrial function. Best Pract Res Clin Endocrinol Metab , 26 (6) 711 - 723. 10.1016/j.beem.2012.05.003. An open access publication

Osellame, LD and Rahim, A and Gegg, ME and Waddington, S and Schapira, AHV and Duchen, MR (2012) Accumulation of damaged mitochondria in neuropathic Gaucher disease, the most prevalent risk factor for Parkinson's disease, is due to defective cellular degradation machinery. In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. (pp. S79 - S80).

Papkovskaia, TD and Chau, KY and Inesta-Vaquera, F and Papkovsky, DB and Healy, DG and Nishio, K and Staddon, J and Duchen, MR and Hardy, J and Schapira, AH and Cooper, JM (2012) G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization. Hum Mol Genet , 21 (19) 4201 - 4213. 10.1093/hmg/dds244. An open access publication

Schwarzländer, M and Murphy, MP and Duchen, MR and Logan, DC and Fricker, MD and Halestrap, AP and Müller, FL and Rizzuto, R and Dick, TP and Meyer, AJ and Sweetlove, LJ (2012) Mitochondrial 'flashes': a radical concept repHined. Trends Cell Biol , 22 (10) 503 - 508. 10.1016/j.tcb.2012.07.007.

Traba, J and Del Arco, A and Duchen, MR and Szabadkai, G and Satrústegui, J (2012) SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca(2+) buffering. Cell Death Differ , 19 (4) 650 - 660. 10.1038/cdd.2011.139.

2011

Abeti, R and Abramov, AY and Duchen, MR (2011) beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death. BRAIN , 134 1658 - 1672. 10.1093/brain/awr104.

Abramov, AY and Duchen, MR (2011) Measurements of threshold of mitochondrial permeability transition pore opening in intact and permeabilized cells by flash photolysis of caged calcium. Methods Mol Biol , 793 299 - 309. 10.1007/978-1-61779-328-8_19.

Abramov, AY and Ionov, M and Pavlov, E and Duchen, MR (2011) Membrane cholesterol content plays a key role in the neurotoxicity of beta-amyloid: implications for Alzheimer's disease. AGING CELL , 10 (4) 595 - 603. 10.1111/j.1474-9726.2011.00685.x.

Duchen, MR and Heath, K and Baruch, NB and Hanna, MG and Muntoni, F (2011) Dysregulation of calcium and mitochondrial function as potential therapeutic targets in muscle disease. In: NEUROMUSCULAR DISORDERS. (pp. S1 - S2). PERGAMON-ELSEVIER SCIENCE LTD

Hall, AM and Crawford, C and Unwin, RJ and Duchen, MR and Peppiatt-Wildman, CM (2011) Multiphoton Imaging of the Functioning Kidney. J AM SOC NEPHROL , 22 (7) 1297 - 1304. 10.1681/ASN.2010101054.

2010

Abramov, AY and Duchen, MR (2010) Impaired mitochondrial bioenergetics determines glutamate-induced delayed calcium deregulation in neurons. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS , 1800 (3) 297 - 304. 10.1016/j.bbagen.2009.08.002.

Abramov, AY and Smulders-Srinivasan, TK and Kirby, DM and Acin-Perez, R and Enriquez, JA and Lightowlers, RN and Duchen, MR and Turnbull, DM (2010) Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations. BRAIN , 133 797 - 807. 10.1093/brain/awq015.

Ahluwalia, J and Tinker, A and Clapp, LH and Duchen, MR and Abramov, AY and Pope, S and Nobles, M and Segal, AW (2010) The large-conductance Ca2+-activated K+ channel is essential for innate immunity (Retraction of vol 427, pg 853, 2004). NATURE , 468 (7320) 122 - 122. 10.1038/nature09562.

Averaimo, S and Milton, RH and Duchen, MR and Mazzanti, M (2010) Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress. FEBS LETT , 584 (10) 2076 - 2084. 10.1016/j.febslet.2010.02.073.

Duchen, MR and Szabadkai, G (2010) Roles of mitochondria in human disease. ESSAYS BIOCHEM , 47 115 - 137. 10.1042/BSE0470115.

El-Kadi, AM and Bros-Facer, V and Deng, WH and Philpott, A and Stoddart, E and Banks, G and Jackson, GS and Fisher, EMC and Duchen, MR and Greensmith, L and Moore, AL and Hafezparast, M (2010) The Legs at odd angles (Loa) Mutation in Cytoplasmic Dynein Ameliorates Mitochondrial Function in SOD1(G93A) Mouse Model for Motor Neuron Disease. J BIOL CHEM , 285 (24) 18627 - 18639. 10.1074/jbc.M110.129320. An open access publication

Hall, AM and Campanella, M and Loesch, A and Duchen, MR and Unwin, RJ (2010) Albumin Uptake in OK Cells Exposed to Rotenone: A Model for Studying the Effects of Mitochondrial Dysfunction on Endocytosis in the Proximal Tubule? NEPHRON PHYSIOL , 115 (2) P9 - P19. 10.1159/000314540.

Igosheva, N and Abramov, AY and Poston, L and Eckert, JJ and Fleming, TP and Duchen, MR and McConnell, J (2010) Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes. PLOS ONE , 5 (4) , Article e10074. 10.1371/journal.pone.0010074. An open access publication. A version is also available from UCL Discovery.

Munteanu, I and Yasukawa, T and Duchen, MR and Muntoni, F (2010) Uncovering the role of mitochondria in the pathogenesis of core myopathies. In: NEUROMUSCULAR DISORDERS. (pp. S24 - S24). PERGAMON-ELSEVIER SCIENCE LTD

Ng, KE and Schwarzer, S and Duchen, MR and Tinker, A (2010) The Intracellular Localization and Function of the ATP-Sensitive K+ Channel Subunit Kir6.1. J MEMBRANE BIOL , 234 (2) 137 - 147. 10.1007/s00232-010-9241-x.

Traba, J and Amigo, I and Rueda, C and Szabadkai, G and Duchen, MR and Satrustegui, J and del Arco, A (2010) The Ca2+-dependent ATP-Mg/Pi carriers as novel regulators of the mitochondrial permeability transition pore. In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. (pp. 130 - 130). ELSEVIER SCIENCE BV

2009

Campanella, M and Parker, N and Tan, CH and Hall, AM and Duchen, MR (2009) IF1: setting the pace of the F1Fo-ATP synthase. TRENDS BIOCHEM SCI , 34 (7) 343 - 350. 10.1016/j.tibs.2009.03.006.

Campanella, M and Seraphim, A and Abeti, R and Casswell, E and Echave, P and Duchen, MR (2009) IF1, the endogenous regulator of the F1Fo-ATPsynthase, defines mitochondrial volume fraction in HeLa cells by regulating autophagy. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS , 1787 (5) 393 - 401. 10.1016/j.bbabio.2009.02.023.

Cantley, J and Selman, C and Shukla, D and Abramov, AY and Forstreuter, F and Esteban, MA and Claret, M and Lingard, SJ and Clements, M and Harten, SK and Asare-Anane, H and Batterham, RL and Herrera, PL and Persaud, SJ and Duchen, MR and Maxwell, PH and Withers, DJ (2009) Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J CLIN INVEST , 119 (1) 125 - 135. 10.1172/JCI26934.

Dumollard, R and Carroll, J and Duchen, MR and Campbell, K and Swann, K (2009) Mitochondrial function and redox state in mammalian embryos. SEMIN CELL DEV BIOL , 20 (3) 346 - 353. 10.1016/j.semcdb.2008.12.013.

Echave, P and Machado-da-Silva, G and Arkell, RS and Duchen, MR and Jacobson, J and Mitter, R and Lloyd, AC (2009) Extracellular growth factors and mitogens cooperate to drive mitochondrial biogenesis. J CELL SCI , 122 (24) 4516 - 4525. 10.1242/jcs.049734. An open access publication

Galkin, A and Abramov, AY and Frakich, N and Duchen, MR and Moncada, S (2009) Lack of Oxygen Deactivates Mitochondrial Complex I IMPLICATIONS FOR ISCHEMIC INJURY? J BIOL CHEM , 284 (52) 36055 - 36061. 10.1074/jbc.M109.054346. An open access publication

Gandhi, S and Wood-Kaczmar, A and Wood, NW and Duchen, MR and Abramov, AY (2009) PINK1 associated Parkinson's disease is caused by neuronal vulnerability to calcium induced cell death. In: MOVEMENT DISORDERS. (pp. S33 - S33). WILEY-LISS

Gandhi, S and Wood-Kaczmar, A and Yao, Z and Plun-Favreau, H and Deas, E and Klupsch, K and Downward, J and Latchman, DS and Tabrizi, SJ and Wood, NW and Duchen, MR and Abramov, AY (2009) PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death. MOL CELL , 33 (5) 627 - 638. 10.1016/j.molcel.2009.02.013. An open access publication

Hall, AM and Unwin, RJ and Parker, N and Duchen, MR (2009) Multiphoton Imaging Reveals Differences in Mitochondrial Function between Nephron Segments. J AM SOC NEPHROL , 20 (6) 1293 - 1302. 10.1681/ASN.2008070759. An open access publication

Mann, ZF and Duchen, MR and Gale, JE (2009) Mitochondria modulate the spatio-temporal properties of intra- and intercellular Ca2+ signals in cochlear supporting cells. CELL CALCIUM , 46 (2) 136 - 146. 10.1016/j.ceca.2009.06.005.

Szabadkai, G and Duchen, MR (2009) Mitochondria mediated cell death in diabetes. APOPTOSIS , 14 (12) 1405 - 1423. 10.1007/s10495-009-0363-5.

Wood-Kaczmar, A and Gandhi, S and Yao, Z and Abramov, AY and Miljan, EA and Keen, G and Stanyer, L and Hargreaves, I and Klupsch, K and Downward, J and Mansfield, L and Jat, P and Taylor, J and Heales, S and Duchen, MR and Latchman, D and Tabrizi, SJ and Wood, NW (2009) PINK1 is necessary for long term survival and mitochondrial function in primary human dopaminergic neurons. In: JOURNAL OF NEUROCHEMISTRY. (pp. 301 - 302). WILEY-BLACKWELL PUBLISHING, INC

Zolfaghari, P and Singer, M and Duchen, MR (2009) UNCOUPLING PROTEIN-3 MEDIATES THE LOSS OF MITOCHONDRIAL MEMBRANE POTENTIAL IN SEVERE SEPSIS. In: INTENSIVE CARE MEDICINE. (pp. 164 - 164). SPRINGER

2008

Abramov, AY and Duchen, MR (2008) Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS , 1777 (7-8) 953 - 964. 10.1016/j.bbabio.2008.04.017.

Bilsland, LG and Nirmalananthan, N and Yip, J and Greensmith, L and Duchen, MR (2008) Expression of mutant SOD1(G93A) in astrocytes induces functional deficits in motoneuron mitochondria. J NEUROCHEM , 107 (5) 1271 - 1283. 10.1111/j.1471-4159.2008.05699.x.

Campanella, M and Casswell, E and Chong, S and Farah, Z and Wieckowski, MR and Abramov, AY and Tinker, A and Duchen, MR (2008) Regulation of mitochondrial structure and function by the F1FO-ATPase inhibitor protein, IF1. CELL METAB , 8 (1) 13 - 25. 10.1016/j.cmet.2008.06.001.

Duchen, MR and Verkhratsky, A and Muallem, S (2008) Mitochondria and calcium in health and disease. CELL CALCIUM , 44 (1) 1 - 5. 10.1016/j.ceca.2008.02.001.

Hall, AM and Unwin, RJ and Hanna, MG and Duchen, MR (2008) Renal function and mitochondrial cytopathy (MC): more questions than answers. QJM-INT J MED , 101 (10) 755 - 766. 10.1093/qjmed/hcn060.

Milton, RH and Abeti, R and Averaimo, S and DeBiasi, S and Vitellaro, L and Jiang, L and Curmi, PMG and Breit, SN and Duchen, MR and Mazzanti, M (2008) CLIC1 Function Is Required for beta-Amyloid-Induced Generation of Reactive Oxygen Species by Microglia. J NEUROSCI , 28 (45) 11488 - 11499. 10.1523/JNEUROSCI.2431-08.2008.

Szabadkai, G and Duchen, MR (2008) Mitochondria: The hub of cellular Ca2+ signaling (vol 23, pg 84, 2008). PHYSIOLOGY , 23 (4) 230 - 230. 10.1152/physiol.00101.2008.

Szabadkai, G and Duchen, MR (2008) Mitochondria: The hub of cellular Ca2+ signaling. PHYSIOLOGY , 23 (2) 84 - 94. 10.1152/physiol.00046.2007.

Tan, CH and Campanella, M and Seraphim, A and Farah, Z and Conte, A and Duchen, MR (2008) The inhibitory protein 1F(1) regulates cellular sensitivity to staurosporine-induced cell death. In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. (pp. S84 - S85). ELSEVIER SCIENCE BV

Wood-Kaczmar, A and Gandhi, S and Yao, Z and Abramov, ASY and Miljan, EA and Keen, G and Stanyer, L and Hargreaves, I and Klupsch, K and Deas, E and Downward, J and Mansfield, L and Jat, P and Taylor, J and Heales, S and Duchen, MR and Latchman, D and Tabrizi, SJ and Wood, NW (2008) PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons. PLOS ONE , 3 (6) , Article e2455. 10.1371/journal.pone.0002455. An open access publication. A version is also available from UCL Discovery.

2007

Abramov, AY and Fraley, C and Diao, CT and Winkfein, R and Colicos, MA and Duchen, MR and French, RJ and Pavlov, E (2007) Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death. P NATL ACAD SCI USA , 104 (46) 18091 - 18096. 10.1073/pnas.0708959104. An open access publication

Abramov, AY and Scorziello, A and Duchen, MR (2007) Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J NEUROSCI , 27 (5) 1129 - 1138. 10.1523/JNEUROSCI.4468-06.2007.

Campanella, M and Tinker, A and Duchen, MR (2007) Studies of the endogenous inhibitor of the mitochondrial ATPase, IFt, in intact cells. In: BIOPHYSICAL JOURNAL. (pp. 640A - 640A). BIOPHYSICAL SOCIETY

Davidson, SM and Duchen, MR (2007) Endothelial mitochondria - Contributing to vascular function and disease. CIRC RES , 100 (8) 1128 - 1141. 10.1161/01.RES.0000261970.18328.1d.

Davidson, SM and Yellon, D and Duchen, MR (2007) Assessing mitochondrial potential, calcium, and redox state in isolated mammalian cells using confocal microscopy. Methods Mol Biol , 372 421 - 430. 10.1007/978-1-59745-365-3_30.

Dumollard, R and Duchen, M and Carroll, J (2007) The role of mitochondrial function in the oocyte and embryo. CURR TOP DEV BIOL , 77 21 - +. 10.1016/S0070-2153(06)77002-8.

Dumollard, R and Ward, Z and Carroll, J and Duchen, MR (2007) Regulation of redox metabolism in the mouse oocyte and embryo. DEVELOPMENT , 134 (3) 455 - 465. 10.1242/dev.02744.

Dumollard, R and Ward, Z and Carroll, J and Duchen, MR (2007) Regulation of redox metabolism in the mouse oocyte and embryo. Development , 134 (3) 455 - 465.

McKenzie, M and Liolitsa, D and Akinshina, N and Campanella, M and Sisodiya, S and Hargreaves, I and Nirmalananthan, N and Sweeney, MG and Abou-Sleiman, PM and Wood, NW and Hanna, MG and Duchen, MR (2007) Mitochondrial ND5 gene variation associated with encephalomyopathy and mitochondrial ATP consumption. J BIOL CHEM , 282 (51) 36845 - 36852. 10.1074/jbc.M704158200. An open access publication

Ogston, NC and Sharpe, MA and Flachs, P and Ricquier, D and Kopecky, J and Duchen, MR and Mohamed-Ali, V (2007) Uncoupling protein-2 expression and activity in white adipocytes: modulation of mitochondrial membrane potential and cellular redox state in response to lipid load and reactive oxygen species. DIABETIC MED , 24 41 - 41.

2006

Brennan, JP and Berry, RG and Baghai, M and Duchen, MR and Shattock, MJ (2006) FCCP is cardioprotective at concentrations that cause mitochondrial oxidation without detectable depolarisation. CARDIOVASC RES , 72 (2) 322 - 330. 10.1016/j.cardiores.2006.08.006.

Brennan, JP and Southworth, R and Medina, RA and Davidson, SM and Duchen, MR and Shattock, MJ (2006) Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of K-ATP channel activation. CARDIOVASC RES , 72 (2) 313 - 321. 10.1016/j.cardiores.2006.07.019.

Davidson, SM and Duchen, MR (2006) Calcium microdomains and oxidative stress. CELL CALCIUM , 40 (5-6) 561 - 574. 10.1016/j.ceca.2006.08.017.

Davidson, SM and Duchen, MR (2006) Effects of NO on mitochondrial function in cardiomyocytes: Pathophysiological relevance. CARDIOVASC RES , 71 (1) 10 - 21. 10.1016/j.cardiores.2006.01.019.

Davidson, SM and Hausenloy, D and Duchen, MR and Yellon, DM (2006) Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection. INT J BIOCHEM CELL B , 38 (3) 414 - 419. 10.1016/j.biocel.2005.09.017.

Dumollard, R and Duchen, M and Sardet, C (2006) Calcium signals and mitochondria at fertilisation. Seminars in Cell and Developmental Biology , 17 (2) 314 - 323. 10.1016/j.semcdb.2006.02.009.

Jia, HY and Bagherzadeh, A and Bicknell, R and Duchen, MR and Liu, D and Zachary, I (2006) Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells (vol 279, pg 36148, 2004). J BIOL CHEM , 281 (8) 5328 - 5328. An open access publication

Smart, N and Mojet, MH and Latchman, DS and Marber, MS and Duchen, MR and Heads, RJ (2006) IL-6 induces PI 3-kinase and nitric oxide-dependent protection and preserves mitochondrial function in cardiomyocytes. CARDIOVASC RES , 69 (1) 164 - 177. 10.1016/j.cardiores.2005.08.017.

2005

Abramov, AY and Canevari, L and Duchen, MR (2005) Expression, function and modulation of an NADPH oxidase in mammalian astrocytes. In: BIOPHYSICAL JOURNAL. (pp. 256A - 257A). BIOPHYSICAL SOCIETY

Abramov, AY and Duchen, MR (2005) The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES , 360 (1464) 2309 - 2314. 10.1098/rstb.2005.1766. An open access publication

Abramov, AY and Duchen, MR (2005) Mechanisms underlying the loss of mitochondrial potential calcium homeostasis in neurons during glutamate excitotoxicity. In: JOURNAL OF NEUROCHEMISTRY. (pp. 246 - 246).

Abramov, AY and Jacobson, J and Wientjes, F and Hothersall, J and Canevari, L and Duchen, MR (2005) Expression and modulation of an NADPH oxidase in mammalian astrocytes. J NEUROSCI , 25 (40) 9176 - 9184. 10.1523/JNEUROSCI.1632-05.2005.

Abrarnov, AY and Wientjes, F and Canevari, L and Duchen, MR (2005) An NADPH oxidase in astrocytes: Expression, function and pathophysiological role in the neurotoxicity of beta amyloid. In: JOURNAL OF NEUROCHEMISTRY. (pp. 66 - 66). BLACKWELL PUBLISHING

Jacobson, J and Duchen, MR and Hothersall, J and Clark, JB and Heales, SJR (2005) Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism. J NEUROCHEM , 95 (2) 388 - 395. 10.1111/j.1471-4159.2005.03374.x.

Kouri, K and Duchen, MR and Lemmens-Gruber, R (2005) Effects of beauvericin on the metabolic state and ionic homeostasis of ventricular myocytes of the guinea pig. CHEM RES TOXICOL , 18 (11) 1661 - 1668. 10.1021/tx050096g.

Liolitsa, D and McKenzie, M and Hargreaves, I and Heales, S and Land, J and Sisodiya, SM and Wood, NW and Duchen, MR and Hanna, MG (2005) MELAS, a young-onset stroke disorder associated with a homoplasmic ND5 mitochondrial DNA mutation. EUR J NEUROL , 12 158 - 159.

Pitter, JG and Szanda, G and Duchen, MR and Spat, A (2005) Prostaglandin F-2 alpha potentiates the calcium dependent activation of mitochondrial metabolism in luteal cells. CELL CALCIUM , 37 (1) 35 - 44. 10.1016/j.ceca.2004.06.004.

Shanmuganathan, S and Hausenloy, DJ and Duchen, MR and Yellon, DM (2005) Mitochondrial permeability transition pore as a target for cardioprotection in the human heart. AM J PHYSIOL-HEART C , 289 (1) H237 - H242. 10.1152/ajpheart.01192.2004.

2004

Abramov, A.Y. and Canevari, L. and Duchen, M.R. (2004) β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. Journal of Neuroscience , 24 (2) pp. 565-575. 10.1523/JNEUROSCI.4042-03.2004. An open access version is available from UCL Discovery

Abramov, AY and Canevari, L and Duchen, MR (2004) Calcium signals induced by amylold beta peptide and their consequences in neurons and astrocytes in culture. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH , 1742 (1-3) 81 - 87. 10.1016/j.bbamcr.2004.09.006.

Abramov, AY and Canevari, L and Duchen, MR (2004) beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J NEUROSCI , 24 (2) 565 - 575. 10.1523/JNEUROSCI.4042-03.2004.

Abramov, AY and Canevari, L and Duchen, MR (2004) Amyloid beta peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. In: BIOPHYSICAL JOURNAL. (pp. 469A - 469A). BIOPHYSICAL SOCIETY

Ahluwalia, J and Tinker, A and Clapp, LH and Duchen, MR and Abramov, AY and Pope, S and Nobles, M and Segal, AW (2004) The large-conductance Ca2+-activated K+ channel is essential for innate immunity (Retracted article. See vol. 468, 2010). NATURE , 427 (6977) 853 - 858. 10.1038/nature02356.

Ahluwalia, J. and Tinker, A. and Clapp, L.H. and Duchen, M.R. and Abramov, A.Y. and Pope, S. and Nobles, M. and Segal, A.W. (2004) The large-conductance Ca2+ -activated K+ channel is essential for innate immunity. Nature , 427 (6977) pp. 853-858. 10.1038/nature02356.

Canevari, L and Abramov, AY and Duchen, MR (2004) Toxicity of amyloid beta peptide: Tales of calcium, mitochondria, and oxidative stress. NEUROCHEM RES , 29 (3) 637 - 650.

Davidson, SM and Hausenloy, D and Duchen, MR and Yellon, DM (2004) Insulin inhibits opening of the mitochondrial permeability transition pore via the reperfusion injury salvage kinase (RISK) pathway. In: CIRCULATION. (pp. 29 - 29). LIPPINCOTT WILLIAMS & WILKINS

Duchen, MR (2004) Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol Aspects Med , 25 (4) 365 - 451. 10.1016/j.mam.2004.03.001.

Duchen, MR (2004) Roles of mitochondria in health and disease. DIABETES , 53 S96 - S102.

Dumollard, R and Marangos, P and Fitzharris, G and Swann, K and Duchen, M and Carroll, J (2004) Sperm-triggered [Ca2+] oscillations and Ca2+ homeostasis in the mouse egg have an absolute requirement for mitochondrial ATP production. DEVELOPMENT , 131 (13) 3057 - 3067. 10.1242/dev.01181.

Hausenloy, D and Wynne, A and Duchen, M and Yellon, D (2004) Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. CIRCULATION , 109 (14) 1714 - 1717. 10.1161/01.CIR.0000126294.81407.7D. An open access version is available from UCL Discovery

Hausenloy, DJ and Wynne, A and Duchen, M and Yellon, DM (2004) Does the mitochondrial permeability transition pore have a role in preconditioning?-letter to editor. UNSPECIFIED

Hausenloy, DJ and Yellon, DM and Mani-Babu, S and Duchen, MR (2004) Preconditioning protects by inhibiting the mitochondrial permeability transition. AM J PHYSIOL-HEART C , 287 (2) H841 - H849. 10.1152/ajpheart.00678.2003.

Jacobson, J and Duchen, MR (2004) Interplay between mitochondria and cellular calcium signalling. MOL CELL BIOCHEM , 256 (1-2) 209 - 218.

Jia, HY and Bagherzadeh, A and Bicknell, R and Duchen, MR and Liu, D and Zachary, I (2004) Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells. J BIOL CHEM , 279 (34) 36148 - 36157. 10.1074/jbc.M401538200. An open access publication

Rizzuto, R and Duchen, MR and Pozzan, T (2004) Flirting in little space: the ER/mitochondria Ca2+ liaison. Sci STKE , 2004 (215) re1 - ?. 10.1126/stke.2152004re1.

Rizzuto, R and Duchen, MR and Pozzan, T (2004) Flirting in little space: the ER/mitochondria Ca2+ liaison. Sci STKE , 215 re1, 13 - ?.

Shanmuganathan, S and Hausenloy, DJ and Duchen, MR and Yellon, DM (2004) Inhibiting mitochondrial permeability transition pore opening protects the human myocardium from ischemia-reperfusion injury. In: CIRCULATION. (pp. 235 - 235). LIPPINCOTT WILLIAMS & WILKINS

Surin, AM and Storozhevykh, TP and Vinskaya, NP and Pinelis, VG and Duchen, MR and Khodorov, BI (2004) Does mitochondrial ATp synthase reversal play a crucial role in glutamate-induced deterioration of Ca2+ homeostasis in mature hippocampal cultured neurons? BIOL MEMBRANY , 21 (2) 157 - 159.

2003

Abramov, A.Y. and Canevari, L. and Duchen, M.R. (2003) Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity. Nature Chemical Biology , 23 (12) pp. 5088-5095. An open access version is available from UCL Discovery

Abramov, AY and Canevari, L and Duchen, MR (2003) Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity. J NEUROSCI , 23 (12) 5088 - 5095.

Abramov, AY and Canevari, L and Duchen, MR (2003) Amyloid beta peptide causes [Ca2+](c) fluctuations and decreases [GSH] in rat astrocytes. In: BIOPHYSICAL JOURNAL. (pp. 389A - 389A). BIOPHYSICAL SOCIETY

Abramov, AY and Duchen, MR (2003) Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells. CELL CALCIUM , 33 (2) 101 - 112.

Duchen, MR (2003) Mitochondria and calcium signalling; point counter point. In: Berridge, M, (ed.) Handbook of Cell Signalling. (73 - 77). Elsevier: USA.

Duchen, MR and Surin, A and Jacobson, J (2003) Imaging mitochondrial function in intact cells. METHOD ENZYMOL , 361 353 - 389.

Hausenloy, D.J. and Duchen, M.R. and Yellon, D.M. (2003) Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia–reperfusion injury. Cardiovascular Research , 60 (3) pp. 617-625. 10.1016/j.cardiores.2003.09.025.

Hausenloy, DJ and Duchen, MR and Yellon, DM (2003) Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury. CARDIOVASC RES , 60 (3) 617 - 625. 10.1016/j.cardiores.2003.09.025.

Hausenloy, DJ and Wynne, AM and Duchen, MR and Yellon, DM (2003) Transient mitochondrial permeability transition pore opening mediates ischemic preconditioning-induced protection. In: CIRCULATION. (pp. 220 - 220). LIPPINCOTT WILLIAMS & WILKINS

Monastyrkaya, EA and Andreeva, LV and Duchen, MR and Manuknina, EB and Malyshev, IY (2003) Direct and cross-protective effects of heat adaptation in cultured cells. B EXP BIOL MED+ , 135 (2) 127 - 129.

Monastyrskaya, EA and Andreeva, LV and Duchen, MR and Wiegant, F and Bayda, LA and Manukhina, EB and Malyshev, IY (2003) Adaptation to heat of cardiomyoblasts in culture protects them against heat shock: Role of nitric oxide and heat shock proteins. BIOCHEMISTRY-MOSCOW+ , 68 (7) 816 - 821.

Monastyrskaya, EA and Duchen, MR and Andreeva, LV and Viegant, F and Manukhina, EB and Malyshev, IY (2003) Antiapoptotic effect of heat adaptation in cultured cells. B EXP BIOL MED+ , 135 (2) 123 - 126.

2002

Brennan, JP and Duchen, MR and Shattock, MJ (2002) The anti-ischemic effect of low-dose FCCP involves mitochondrial oxidation without detectable depolarisation. J MOL CELL CARDIOL , 34 (6) A13 - A13.

Casley, CS and Land, JM and Sharpe, MA and Clark, JB and Duchen, MR and Canevari, L (2002) beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons. NEUROBIOL DIS , 10 (3) 258 - 267.

Duchen, MR (2002) Roles of mitochondria, calcium and NO in glutamate excitotoxicity. In: JOURNAL OF PHYSIOLOGY-LONDON. (pp. 10S - 10S). CAMBRIDGE UNIV PRESS

Duchen, MR and Surin, AM (2002) On the roles of mitochondria and calcium in glutamate induced neurotoxicity in hippocampal neurons in culture. BIOL MEMBRANY , 19 (1) 4 - 16.

Hausenloy, DJ and Mani-Babu, S and Duchen, MR and Yellon, DM (2002) Mitochondrial KATP channel activation protects the myocyte against oxidative stress by inhibiting mitochondrial permeability transition pore opening. In: CIRCULATION. (pp. 230 - 230). LIPPINCOTT WILLIAMS & WILKINS

Jacobson, J and Duchen, MR (2002) Mitochondrial oxidative stress and cell death in astrocytes - requirement for stored Ca2+ and sustained opening of the permeability transition pore. J CELL SCI , 115 (6) 1175 - 1188.

Jacobson, J and Duchen, MR and Heales, SJR (2002) Intracellular distribution of the fluorescent dye nonyl acridine orange responds to the mitochondrial membrane potential: implications for assays of cardiolipin and mitochondrial mass. J NEUROCHEM , 82 (2) 224 - 233.

Krieger, C and Duchen, MR (2002) Mitochondria, Ca2+ and neurodegenerative disease. EUR J PHARMACOL , 447 (2-3) 177 - 188.

Mohamed-Ali, V and Goodrick, SJ and Erusalimsky, JD and Mathur, A and Sharpe, M and Duchen, MR (2002) Redox state, mitochondrial membrane potential and UCP expression in relation to lipid content in adipocytes. BIOPHYS J , 82 (1) 344A - 344A.

Robb, SJ and Brealey, D and Karyampudi, S and Duchen, MR and Bellingan, G and Singer, M (2002) Decrease in VO2 in renal tubules from septic rats relates to clinical severity and nitric oxide. In: INTENSIVE CARE MEDICINE. (pp. S64 - S64). SPRINGER-VERLAG

Robb, SJ and Goss, A and Duchen, MR and Singer, M (2002) Nitric oxide independent inhibition of the mitochondrial respiratory chain in HepG2 cells. In: INTENSIVE CARE MEDICINE. (pp. S63 - S63). SPRINGER-VERLAG

Song, GJ and Harding, SE and Duchen, MR and Tunwell, R and O'Gara, P and Hawkins, TE and Moss, SE (2002) Altered mechanical properties and intracellular calcium signaling in cardiomyocytes from annexin 6 null-mutant mice. FASEB J , 16 (2) 622 - +. 10.1096/fj.01-0892fje.

2001

Duchen, M and Mojet, M and Jacobson, DJ and Keelan, J and Vergun, O (2001) Imaging mitochondrial function in single cells. In: Periasamy, A, (ed.) Methods in Cellular Imaging. (88 - 111). American Physiological Society, Oxford University Press

Jacobson, J and Duchen, MR (2001) What nourishes me, destroys me': towards a new mitochondrial biology. CELL DEATH DIFFER , 8 (10) 963 - 966.

Jacobson, J and Duchen, MR and Clark, JB and Heales, SJR (2001) Assay of mitochondrial cardiolipin content in cortical astrocytes. J NEUROCHEM , 78 25 - 25.

Keelan, J and Allen, NJ and Antcliffe, D and Pal, S and Duchen, MR (2001) Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane. J NEUROSCI RES , 66 (5) 873 - 884.

Rakhit, RD and Mojet, MH and Marber, MS and Duchen, MR (2001) Mitochondria as targets for nitric oxide-induced protection during simulated ischemia and reoxygenation in isolated neonatal cardiomyocytes. CIRCULATION , 103 (21) 2617 - 2623.

Vergun, O and Sobolevsky, AI and Yelshansky, MV and Keelan, J and Khodorov, BI and Duchen, MR (2001) Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture. J PHYSIOL-LONDON , 531 (1) 147 - 163.

2000

Beltran, B and Mathur, A and Duchen, MR and Erusalimsky, JD and Moncada, S (2000) The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death. P NATL ACAD SCI USA , 97 (26) 14602 - 14607.

Duchen, MR (2000) Mitochondria and calcium: from cell signalling to cell death. JOURNAL OF PHYSIOLOGY-LONDON , 529 (1) 57 - 68.

Duchen, MR (2000) Symposium overview. J PHYSIOL-LONDON , 529 (1) 2 - 2.

Duchen, MR (2000) Mitochondria and Ca2+ in cell physiology and pathophysiology. CELL CALCIUM , 28 (5-6) 339 - 348. 10.1054/ceca.2000.0170.

Duchen, MR (2000) Mitochondria and Ca<sup>2+</sup> in cell physiology and pathophysiology<b> </b>. Cell Calcium , 28 (5) 339 - 348.

Keelan, J and Allen, NJ and Antcliffe, D and Pal, S and Heales, S and Duchen, MR (2000) Quantitative confocal microscopic measurement of glutathione levels in mixed hippocampal cultures. J PHYSIOL-LONDON , 525 68P - 69P.

Mojet, M and Jacobson, DJ and Keelan, J and Vergun, O and Duchen, MR (2000) Monitoring mitochondrial function in single cells. In: Tepikin, A, (ed.) Calcium Signalling. (79 - 110). IRL Press,OUP: Oxford.

1999

Ashmore, JF and Bolsover, SR and Cockcroft, S and Duchen, MR and Koffer, A and Moss, SE and Swann, K (1999) Imaging as applied to cell signalling: work from the Physiology Imaging Consortium (UCL.PIC). In: Journal of Physiology. (pp. 25 - ?).

Boitier, E and Rea, R and Duchen, MR (1999) Mitochondria exert a negative feedback on the propagation of intracellular Ca2+ waves in rat cortical astrocytes. J CELL BIOL , 145 (4) 795 - 808.

Boitier, E and Rea, R and Duchen, MR (1999) Modulation of the propagation of intracellular calcium waves by mitochondria in rat cortical astrocytes. In: BIOPHYS J. (pp. A223 - A223). BIOPHYSICAL SOCIETY

Boitier, E and Rea, R and Duchen, MR (1999) Mitochondria exert a negative feedback control on the propagation of intracellular [Ca<sup>2+</sup>]<sub>i</sub> waves in adult rat cortical astrocytes. The Journal of Cell Biology , 145 795 - 808.

Duchen, MR (1999) Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death. J PHYSIOL-LONDON , 516 (1) 1 - 17.

Duchen, MR (1999) Mitochondrial contributions to animal physiology: from homeostatic sensor to calcium signalling and cell death. The Journal of Physiology , 516 1 - 17.

Duchen, MR and Boitier, E and Jacobson, D and Keelan, J and Vergun, O (1999) Imaging mitochondrial function and cytosolic calcium in single mammalian cells. In: Journal of Physiology. (pp. 6 - ?).

Keelan, J and Vergun, O and Duchen, MR (1999) Excitotoxic mitochondrial depolarisation requires both calcium and nitric oxide in rat hippocampal neurons. J PHYSIOL-LONDON , 520 (3) 797 - 813.

Keelan, J and Vergun, O and Duchen, MR (1999) Dynamics of intracellular calcium and mitochondrial potential during excitotoxicity in hippocampal neurons. In: Society for Neuroscience Abstracts. (pp. 1603 - 1603).

Keelan, J and Vergun, O and Duchen, MR (1999) The synergistic action of calcium and nitric oxide causes mitochondrial depolarisation during toxic glutamate exposure in hippocampal neurones. The Journal of Physiology , 520 (3) 797 - 813.

Mojet, MH and Duchen, MR (1999) Imaging transmission spectroscopy in the isolated carotid body (with simultaneous recordings of carotid sinus nerve activity). In: Journal of Physiology. (pp. 5 - ?).

Rakhit, RD and Mojet, MH and Duchen, MR (1999) Mitochondrial depolarisation by nitric oxide protects cardiomyocytes against calcium overload injury during simulated ischemia-reperfusion (I/R). In: CIRCULATION. (pp. 243 - 243). LIPPINCOTT WILLIAMS & WILKINS

Rakhit, RD and Mojet, MH and Edwards, RJ and Aldous, A and Duchen, MR and Marber, MS (1999) Nitric oxide modulates mitochondrial function in neonatal cardiocytes by reversible inhibition of respiration. In: European Heart Journal. (pp. 123 - 123).

Vergun, O and Keelan, J and Duchen, MR (1999) Contribution of reactive oxygen species (ROS) to the mitochondrial depolarization and perturbation of calcium homeostasis associated with glutamate toxicity. In: Society for Neuroscience Abstracts. (pp. 1866 - 1866).

Vergun, O and Keelan, J and Khodorov, BI and Duchen, MR (1999) Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones. J PHYSIOL-LONDON , 519 (2) 451 - 466.

1998

Duchen, MR and Leyssens, A and Crompton, M (1998) Transient mitochondrial depolarizations reflect focal sarcoplasmic reticular calcium release in single rat cardiomyocytes. J CELL BIOL , 142 (4) 975 - 988.

Duchen, MR and Leyssens, A and Crompton, M (1998) Transient mitochondrial depolarisations in response to focal SR calcium release in single rat cardiomyocytes. The Journal of Cell Biology , 142 975 - 988.

Jacobson, D and Duchen, MR (1998) Fluorescence imaging of the mitochondrial permeability transition in rat cortical astrocytes in culture. In: J PHYSIOL-LONDON. (pp. 75P - 76P). CAMBRIDGE UNIV PRESS

Jacobson, D and Duchen, MR (1998) Fluorescence imaging of the mitochondrial permeability transition in rat cortical astrocytes in culture. In: Journal of Physiology. (pp. 75 - ?).

Keelan, J and Hersson-Ringskog, J and Sioftanos, G and Sritharan, K and Vergun, O and Duchen, MR (1998) Nitric oxide contributes to glutamate-induced mitochondrial dysfunction in rat hippocampal neurones in culture. J PHYSIOL-LONDON , 511P 122P - 123P.

Keelan, J and Vergun, O and Duchen, MR (1998) Is there a role for the mitochondrial permeability transition in the initial stages of glutamate excitotoxicity? In: Society for Neuroscience Abstracts. (pp. 1453 - ?).

Keelan, J and Vergun, O and Hersson-Ringskog, J and Sritharan, K and Sioftanos, G and Duchen, MR (1998) Nitric oxide contributes to glutamate-induced mitochondrial dysfunction in rat hippocampal neurons in culture. In: Journal of Physiology. (pp. 122 - ?).

Keelan, J and Vergun, O and Khodorov, B and Duchen, MR (1998) Calcium-dependent mitochondrial depolarisation specific to toxic glutamate stimulation in cultured rat hippocampal neurones. In: Journal of Physiology. (pp. 75 - ?).

Keelan, J and Vergun, O and Khodorov, BI and Duchen, MR (1998) Calcium-dependent mitochondrial depolarization specific to toxic glutamate stimulation in cultured rat hippocampal neurones. In: J PHYSIOL-LONDON. (pp. 75P - 75P). CAMBRIDGE UNIV PRESS

Morris, SH and Keelan, J and Patterson, DL and Duchen, MR and Bindman, LJ (1998) Group I metabotropic glutamate receptor (mGluR) agonists raise intracellular [Ca<sup><i>2+</sup></i>] in medial frontal cortical neurones of the rat. In: Society for Neuroscience Abstracts. (pp. 2024 - ?).

Nowicky, AV and Duchen, MR (1998) Changes in [Ca2+](i) and membrane currents during impaired mitochondrial metabolism in dissociated rat hippocampal neurons. J PHYSIOL-LONDON , 507 (1) 131 - 145.

Nowicky, AV and Duchen, MR (1998) Changes in [Ca<sup>2+</sup>]i and membrane currents in response to impaired mitochondrial metabolism in dissociated rat hippocampal neurons. The Journal of Physiology , 507 131 - 146.

Vergun, O and Khodorov, B and Duchen, MR (1998) Does mitochondrial function underlie the glutamate induced deterioration of neuronal calcium homeostasis? In: Society for Neuroscience Abstracts. (pp. 1452 - ?).

1997

Duchen, MR and Boitier, E and Jacobson, J and Leyssens, A and Peuchen, S (1997) Mitochondria, free radicals & intracellular calcium in cell injury studied in single mammalian cells. In: BIOPHYS J. (pp. WP260 - WP260). BIOPHYSICAL SOCIETY

Keelan, J and Vergun, O and Patterson, DL and Duchen, MR (1997) Excitotoxicity, cellular calcium signalling and mitochondrial (dys)function in cultured hippocampal neurons. In: Society for Neuroscience Abstracts.

Mojet, MH and Mills, E and Duchen, MR (1997) Hypoxia-induced catecholamine secretion in isolated newborn rat adrenal chromaffin cells is mimicked by inhibition of mitochondrial respiration. J PHYSIOL-LONDON , 504 (1) 175 - 189.

Peuchen, S and Bolanos, JP and Heales, S and Duchen, MR and Clark, JB (1997) Interrelationships between astrocyte function, oxidative stress and antioxidant status in the CNS. Progress in Neurobiology , 52 261 - 281.

Peuchen, S and Bolanos, JP and Heales, SJR and Almeida, A and Duchen, MR and Clark, JB (1997) Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system. PROG NEUROBIOL , 52 (4) 261 - 281.

Peuchen, S and Duchen, MR and Clark, JB (1997) Modulation of gluthathione redox state in adult astrocytes. In:

1996

Duchen, MR (1996) Raised intramitochondrial calcium stimulates ATP depletion by the mitochondrial F1F0-ATPase during metabolic inhibition in single mouse sensory neurons in culture. J PHYSIOL-LONDON , 491P P134 - P134.

Duchen, MR and Leyssens, A and Mojet, MH and Peuchen, S (1996) Properties of rhod-2 as an indicator of intra-mitochondrial calcium. In: JOURNAL OF PHYSIOLOGY-LONDON. (pp. P6 - P7). CAMBRIDGE UNIV PRESS

Leyssens, A and Crompton, M and Duchen, MR (1996) A role of the mitochondrial permeability transition pore in cell injury by reactive oxygen species in isolated rat cardiomyocytes. In: JOURNAL OF PHYSIOLOGY-LONDON. (pp. P109 - P110). CAMBRIDGE UNIV PRESS

Leyssens, A and Nowicky, AV and Patterson, L and Crompton, M and Duchen, MR (1996) The relationship between mitochondrial state, ATP hydrolysis, [Mg2+], and [Ca2+](i) studied in isolated rat cardiomyocytes. J PHYSIOL-LONDON , 496 (1) 111 - 128.

Mojet, MH and Mills, E and Duchen, MR (1996) Hypoxia-induced catecholamine secretion by adrenal chromaffin cells isolated from newborn rat is mediated by a fall in [ATP](i) and influx of extracellular Ca2+. In: JOURNAL OF PHYSIOLOGY-LONDON. (pp. P80 - P81). CAMBRIDGE UNIV PRESS

Mojet, MH and Mills, E and Duchen, MR (1996) Hypoxia-induced catecholamine secretion in adrenal chromaffin cells isolated from newborn rat. PROG BIOPHYS MOL BIO , 65 PC101 - PC101.

Peuchen, S and Clark, JB and Duchen, MR (1996) Mechanisms of intracellular calcium regulation in adult astrocytes. NEUROSCIENCE , 71 (3) 871 - 883.

Peuchen, S and Duchen, MR and Clark, JB (1996) Modulation of the glutathione redox state in adult astrocytes. In: BIOCHEMICAL SOCIETY TRANSACTIONS. (pp. S449 - S449). PORTLAND PRESS

Peuchen, S and Duchen, MR and Clark, JB (1996) Modulation of the glutathione redox state in adult astrocytes. Biochem Soc Trans , 24 (3) 449S - ?.

Peuchen, S and Duchen, MR and Clark, JB (1996) Energy metabolism of adult astrocytes in vitro. NEUROSCIENCE , 71 (3) 855 - 870.

1995

LEYSSENS, A and NOWICKY, AV and PATTERSON, L and CROMPTON, M and DUCHEN, MR (1995) CHANGES IN INTRACELLULAR MAGNESIUM AND ATP-REGULATED K+ CHANNEL ACTIVITY WITH CHANGING METABOLIC STATE IN ISOLATED RAT CARDIOMYOCYTES. J PHYSIOL-LONDON , 483P P9 - P10.

LEYSSENS, A and RASTOGHI, R and CRASKE, M and CROMPTON, M and DUCHEN, MR (1995) TRANSIENT DEPOLARIZATIONS OF MITOCHONDRIA LOCALIZED TO DISCRETE AREAS OF SINGLE-RAT CARDIOMYOCYTES CAUSED BY FREE-RADICALS AND LOCAL CALCIUM-RELEASE - A MODEL FOR FREE RADICAL-INDUCED CELL INJURY. J PHYSIOL-LONDON , 487P P123 - P124.

MOJET, MH and MILLS, E and DUCHEN, MR (1995) CHANGES IN MITOCHONDRIAL-FUNCTION, [CA2+](I) AND CATECHOLAMINE SECRETION IN RESPONSE TO HYPOXIA IN CHROMAFFIN CELLS DISSOCIATED FROM THE NEWBORN RAT ADRENAL. J PHYSIOL-LONDON , 487P P59 - P59.

NOWICKY, AV and DUCHEN, MR (1995) INHIBITION OF MITOCHONDRIAL-FUNCTION INDUCES A CALCIUM-DEPENDENT POTASSIUM CURRENT IN DISSOCIATED RAT CA1 HIPPOCAMPAL-NEURONS. J PHYSIOL-LONDON , 487P P60 - P60.

PEARCE, RJ and DUCHEN, MR (1995) ELECTROPHYSIOLOGICAL AND METABOLIC EFFECTS OF A CONVULSANT BARBITURATE ON DISSOCIATED MOUSE PRIMARY SENSORY NEURONS. J PHYSIOL-LONDON , 483 (2) 407 - 420.

SMITH, PA and DUCHEN, MR and ASHCROFT, FM (1995) A FLUOROMETRIC AND AMPEROMETRIC STUDY OF CALCIUM AND SECRETION IN ISOLATED MOUSE PANCREATIC BETA-CELLS. PFLUG ARCH EUR J PHY , 430 (5) 808 - 818.

TERAKAWA, S and KUMAKURA, K and DUCHEN, MR (1995) SPATIOTEMPORAL ANALYSIS OF QUANTAL SECRETORY EVENTS FROM SINGLE BOVINE ADRENAL CHROMAFFIN CELLS IN CULTURE. J PHYSIOL-LONDON , 487P P59 - P60.

1994

DUCHEN, MR and NOWICKY, AV and LEYSSENS, A (1994) SIMULTANEOUS MEASUREMENTS OF MITOCHONDRIAL POTENTIAL AND NAD(P)H AUTOFLUORESCENCE FROM SINGLE ISOLATED MAMMALIAN-CELLS. J PHYSIOL-LONDON , 476P P2 - P3.

DUCHEN, MR and PEUCHEN, S and LEYSSENS, A and NOWICKY, AV and CLARK, JB (1994) IMAGING MITOCHONDRIAL-FUNCTION IN SINGLE ISOLATED MAMMALIAN-CELLS. J PHYSIOL-LONDON , 475P P7 - P8.

LEYSSENS, A and DUCHEN, MR (1994) CHANGES IN INTRACELLULAR FREE MAGNESIUM WITH ATP DEPLETION IN SINGLE ISOLATED RAT CARDIOMYOCYTES. J PHYSIOL-LONDON , 480P P90 - P90.

NOWICKY, AV and DUCHEN, MR (1994) RELATIONSHIP BETWEEN MITOCHONDRIAL POTENTIAL AND INTRACELLULAR CALCIUM IN DISSOCIATED RAT HIPPOCAMPAL-NEURONS. J PHYSIOL-LONDON , 475P P148 - P148.

PEARCE, RJ and DUCHEN, MR (1994) DIFFERENTIAL EXPRESSION OF MEMBRANE CURRENTS IN DISSOCIATED MOUSE PRIMARY SENSORY NEURONS. NEUROSCIENCE , 63 (4) 1041 - 1056.

PEUCHEN, S and CLARK, JB and DUCHEN, MR (1994) CHARACTERIZATION OF [CA2+](I) TRANSIENTS INDUCED BY NUCLEOTIDE RECEPTOR ACTIVATION IN ASTROCYTES CULTURED FROM THE FOREBRAIN OF THE ADULT-RAT. J PHYSIOL-LONDON , 475P P106 - P106.

1993

DUCHEN, MR (1993) VOLTAMMETRIC DETECTION OF QUANTAL SECRETORY EVENTS FROM ISOLATED RAT PERITONEAL MAST-CELLS. J PHYSIOL-LONDON , 467 P2 - P2.

DUCHEN, MR and CROMPTON, M and PEUCHEN, S and NOWICKY, AV (1993) THE USE OF A CARBOCYANINE DYE, JC-1, TO MONITOR CHANGES OF MITOCHONDRIAL POTENTIAL IN ISOLATED MAMMALIAN-CELLS. J PHYSIOL-LONDON , 473 P7 - P7.

DUCHEN, MR and MCGUINNESS, O and BROWN, LA and CROMPTON, M (1993) ON THE INVOLVEMENT OF A CYCLOSPORINE-A SENSITIVE MITOCHONDRIAL PORE IN MYOCARDIAL REPERFUSION INJURY. CARDIOVASC RES , 27 (10) 1790 - 1794.

DUCHEN, MR and PEUCHEN, S and NOWICKY, A (1993) CHANGES IN MITOCHONDRIAL-FUNCTION IN RESPONSE TO CHANGES IN CYTOSOLIC CA-2+ CONCENTRATION. In: BIOMEDICAL RESEARCH-TOKYO. (pp. 139 - 146). BIOMED RES FOUND An open access publication

DUCHEN, MR and SMITH, PA and ASHCROFT, FM (1993) SUBSTRATE-DEPENDENT CHANGES IN MITOCHONDRIAL-FUNCTION, INTRACELLULAR FREE CALCIUM-CONCENTRATION AND MEMBRANE CHANNELS IN PANCREATIC BETA-CELLS. BIOCHEM J , 294 35 - 42.

DUCHEN, MR and SMITH, PA and ASHCROFT, FM (1993) SUBSTRATE-DEPENDENT CHANGES IN MITOCHONDRIAL-FUNCTION, [CA-2+]I AND KATP CHANNELS IN MOUSE PANCREATIC BETA-CELLS INVITRO. J PHYSIOL-LONDON , 459 P266 - P266.

NOWICKY, AV and PEUCHEN, S and CLARK, JB and DUCHEN, MR (1993) SIMULTANEOUS MEASUREMENTS OF INTRACELLULAR CALCIUM AND MITOCHONDRIAL POTENTIAL IN ISOLATED MAMMALIAN-CELLS. J PHYSIOL-LONDON , 473 P10 - P10.

PEUCHEN, S and CLARK, JB and DUCHEN, MR (1993) CHANGES IN [CA2+](I) IN RESPONSE TO ATP IN ASTROCYTES CULTURED FROM THE FOREBRAIN OF THE ADULT-RAT. J PHYSIOL-LONDON , 473 P42 - P42.

PEUCHEN, S and DUCHEN, MR and CLARK, JB (1993) MODULATION OF INTRACELLULAR CALCIUM IN CULTURED ADULT MAMMALIAN ASTROCYTES. J NEUROCHEM , 61 S44 - S44.

1992

DUCHEN, MR (1992) CA2+-DEPENDENT CHANGES IN THE MITOCHONDRIAL ENERGETICS IN SINGLE DISSOCIATED MOUSE SENSORY NEURONS. BIOCHEM J , 283 41 - 50.

DUCHEN, MR and BISCOE, TJ (1992) MITOCHONDRIAL-FUNCTION IN TYPE-I CELLS ISOLATED FROM RABBIT ARTERIAL CHEMORECEPTORS. J PHYSIOL-LONDON , 450 13 - 31.

DUCHEN, MR and BISCOE, TJ (1992) RELATIVE MITOCHONDRIAL-MEMBRANE POTENTIAL AND [CA2+]I IN TYPE-I CELLS ISOLATED FROM THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 450 33 - 61.

PEARCE, RJ and DUCHEN, MR (1992) ACTIONS OF THE CONVULSANT BARBITURATE 5-(2-CYCLOHEXYLIDINE-ETHYL)-5-ETHYL BARBITURIC-ACID (CHEB) ON DISSOCIATED MOUSE SENSORY NEURONS. J PHYSIOL-LONDON , 446 P136 - P136.

1991

DUCHEN, MR (1991) CALCIUM-INDUCED CHANGES IN MITOCHONDRIAL-FUNCTION IN SINGLE DISSOCIATED MOUSE NEURONS. J PHYSIOL-LONDON , 438 P206 - P206.

FARQUHARSON, D and DUCHEN, MR and PEARCE, RJ and BISCOE, TJ (1991) APPARATUS FOR SIMULTANEOUS FLASH-PHOTOLYSIS AND MICROFLUORIMETRY. J PHYSIOL-LONDON , 438 P142 - P142.

TATHAM, PER and DUCHEN, MR and MILLAR, J (1991) MONITORING EXOCYTOSIS FROM SINGLE MAST-CELLS BY FAST VOLTAMMETRY. PFLUG ARCH EUR J PHY , 419 (3-4) 409 - 414.

1990

BISCOE, TJ and DUCHEN, MR (1990) MONITORING PO2 BY THE CAROTID CHEMORECEPTOR. NEWS PHYSIOL SCI , 5 229 - 233.

BISCOE, TJ and DUCHEN, MR (1990) RESPONSES OF TYPE-I CELLS DISSOCIATED FROM THE RABBIT CAROTID-BODY TO HYPOXIA. J PHYSIOL-LONDON , 428 39 - 59.

BISCOE, TJ and DUCHEN, MR (1990) CELLULAR BASIS OF TRANSDUCTION IN CAROTID CHEMORECEPTORS. AM J PHYSIOL , 258 (6) L271 - L278.

DUCHEN, MR (1990) EFFECTS OF METABOLIC INHIBITION ON THE MEMBRANE-PROPERTIES OF ISOLATED MOUSE PRIMARY SENSORY NEURONS. J PHYSIOL-LONDON , 424 387 - 409.

DUCHEN, MR and BISCOE, TJ (1990) CHANGES IN MITOCHONDRIAL-MEMBRANE POTENTIAL AND [CA-2+]I WITH HYPOXIA IN TYPE-I CELLS ISOLATED FROM THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 426 P65 - P65.

DUCHEN, MR and BISCOE, TJ and VALDEOLMILLOS, M (1990) BIOPHYSICAL STUDIES OF CELLS FROM THE CAROTID-BODY OF THE RABBIT. In: EYZAGUIRRE, C and FIDONE, SJ and FITZGERALD, RS and LAHIRI, S and MCDONALD, DM, (eds.) ARTERIAL CHEMORECEPTION. (pp. 31 - 43). SPRINGER-VERLAG

DUCHEN, MR and MILLAR, J and BISCOE, TJ (1990) VOLTAMMETRIC MEASUREMENT OF CATECHOLAMINE RELEASE FROM ISOLATED RAT CHROMAFFIN CELLS. J PHYSIOL-LONDON , 426 P5 - P5.

DUCHEN, MR and PEARCE, RJ and BISCOE, TJ (1990) USE OF MICROFLUORIMETRY TO MONITOR MITOCHONDRIAL-MEMBRANE POTENTIAL IN SINGLE DISSOCIATED MAMMALIAN-CELLS. J PHYSIOL-LONDON , 426 P2 - P2.

DUCHEN, MR and VALDEOLMILLOS, M and ONEILL, SC and EISNER, DA (1990) EFFECTS OF METABOLIC BLOCKADE ON THE REGULATION OF INTRACELLULAR CALCIUM IN DISSOCIATED MOUSE SENSORY NEURONS. J PHYSIOL-LONDON , 424 411 - 426.

PEARCE, RJ and DUCHEN, MR (1990) DIFFERENTIAL EXPRESSION OF MEMBRANE CURRENTS IN ISOLATED MOUSE PRIMARY SENSORY NEURONS. J PHYSIOL-LONDON , 425 P70 - P70.

1989

BISCOE, TJ and DUCHEN, MR (1989) HYPOXIA RAISES INTRACELLULAR CALCIUM IN TYPE-I CELLS ISOLATED FROM THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 418 P128 - P128.

BISCOE, TJ and DUCHEN, MR (1989) ELECTROPHYSIOLOGICAL RESPONSES OF DISSOCIATED TYPE-I CELLS OF THE RABBIT CAROTID-BODY TO CYANIDE. J PHYSIOL-LONDON , 413 447 - 468.

BISCOE, TJ and DUCHEN, MR and EISNER, DA and ONEILL, SC and VALDEOLMILLOS, M (1989) MEASUREMENTS OF INTRACELLULAR CA-2+ IN DISSOCIATED TYPE-I CELLS OF THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 416 421 - 434.

BISCOE, TJ and DUCHEN, MR and FRY, JP and RICKETS, C (1989) PURIFICATION AND ACTIONS OF ENDOGENOUS BENZODIAZEPINE-LIKE IMMUNOREACTIVITY ISOLATED FROM THE BRAIN OF THE MOUSE. J PHYSIOL-LONDON , 415 P50 - P50.

DUCHEN, MR (1989) GABAA RESPONSES OF DISSOCIATED MOUSE NEURONS ARE ATTENUATED BY METABOLIC BLOCKADE. J PHYSIOL-LONDON , 415 P48 - P48.

DUCHEN, MR and PEARCE, RJ (1989) A PREPARATION OF NEURONS FRESHLY DISSOCIATED FROM MOUSE DORSAL-ROOT GANGLIA FOR ELECTROPHYSIOLOGICAL STUDY. J PHYSIOL-LONDON , 415 P6 - P6.

1988

BISCOE, TJ and DUCHEN, MR and EISNER, DA and ONEILL, SC and VALDEOLMILLOS, M (1988) THE EFFECTS OF GLUCOSE REMOVAL AND CYANIDE ON INTRACELLULAR CA-2+ IN ISOLATED, SINGLE-MOUSE DORSAL-ROOT GANGLION-CELLS. J PHYSIOL-LONDON , 401 P60 - P60.

BISCOE, TJ and DUCHEN, MR and EISNER, DA and ONEILL, SC and VALDEOLMILLOS, M (1988) CYANIDE INCREASES [CA-2+]I IN ISOLATED TYPE-I CELLS FROM THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 396 P99 - P99.

BISCOE, TJ and DUCHEN, MR and KIRBY, GC and PATTERSON, DL and PONTE, J (1988) VOLTAGE-CLAMP STUDY OF THE EFFECTS OF CYANIDE ON DISSOCIATED TYPE-I CELLS OF THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 396 P178 - P178.

DUCHEN, MR and CADDY, KWT and KIRBY, GC and PATTERSON, DL and PONTE, J and BISCOE, TJ (1988) BIOPHYSICAL STUDIES OF THE CELLULAR-ELEMENTS OF THE RABBIT CAROTID-BODY. NEUROSCIENCE , 26 (1) 291 - 311.

DUCHEN, MR and SOMJEN, GG (1988) EFFECTS OF CYANIDE AND LOW GLUCOSE ON THE MEMBRANE CURRENTS OF DISSOCIATED MOUSE PRIMARY SENSORY NEURONS. J PHYSIOL-LONDON , 401 P61 - P61.

1987

BISCOE, TJ and CADDY, KWT and DUCHEN, MR and KIRBY, GC and PATTERSON, DL and PONTE, J (1987) PREPARATION AND IDENTIFICATION OF FRESHLY DISSOCIATED CELLS FROM THE RABBIT CAROTID-BODY FOR ELECTROPHYSIOLOGICAL STUDY. J PHYSIOL-LONDON , 392 P11 - P11.

BISCOE, TJ and DUCHEN, MR and KIRBY, GC and PATTERSON, DL and PONTE, J (1987) ELECTROPHYSIOLOGICAL CHARACTERIZATION OF FRESHLY DISSOCIATED TYPE-I CELLS FROM THE RABBIT CAROTID-BODY. J PHYSIOL-LONDON , 392 P36 - P36.

BISCOE, TJ and DUCHEN, MR and PATTERSON, DL (1987) DUAL ACTIONS OF GLYCINE ON DISSOCIATED MOUSE SPINAL NEURONS. J PHYSIOL-LONDON , 382 P133 - P133.

YU, YB and DUCHEN, MR and BISCOE, TJ (1987) PRIMARY AFFERENT TERMINAL EXCITABILITY IN THE NORMAL AND SPASTIC MUTANT MOUSE SPINAL-CORD. EUR J PHARMACOL , 141 (3) 371 - 382.

1986

BISCOE, TJ and DUCHEN, MR (1986) SYNAPTIC PHYSIOLOGY OF SPINAL MOTONEURONS OF NORMAL AND SPASTIC MICE - AN INVITRO STUDY. J PHYSIOL-LONDON , 379 275 - 292.

BISCOE, TJ and DUCHEN, MR and PATTERSON, L (1986) VOLTAGE-CLAMP STUDY OF ACUTELY DISSOCIATED MOUSE SPINAL NEURONS. J PHYSIOL-LONDON , 377 P10 - P10.

DUCHEN, MR (1986) EXCITATION OF MOUSE MOTONEURONS BY GABA-MEDIATED PRIMARY AFFERENT DEPOLARIZATION. BRAIN RES , 379 (1) 182 - 187.

1985

BISCOE, TJ and DUCHEN, MR (1985) ACTIONS AND INTERACTIONS OF GABA AND BENZODIAZEPINES IN THE MOUSE HIPPOCAMPAL SLICE. Q J EXP PHYSIOL CMS , 70 (3) 313 - 328.

BISCOE, TJ and DUCHEN, MR (1985) AN INTRACELLULAR STUDY OF DENTATE, CA1 AND CA3 NEURONS IN THE MOUSE HIPPOCAMPAL SLICE. Q J EXP PHYSIOL CMS , 70 (2) 189 - 202.

BISCOE, TJ and DUCHEN, MR (1985) THE ANION SELECTIVITY OF GABA-MEDIATED POST-SYNAPTIC POTENTIALS IN MOUSE HIPPOCAMPAL CELLS. Q J EXP PHYSIOL CMS , 70 (3) 305 - 312.

BISCOE, TJ and DUCHEN, MR and WILSON, MGA (1985) USE OF THE RML MICROCOMPUTER 380Z FOR ONLINE TESTING OF PRIMARY AFFERENT TERMINAL EXCITABILITY IN THE MOUSE SPINAL-CORD INVITRO. J PHYSIOL-LONDON , 365 (AUG) P2 - P2.

DUCHEN, MR (1985) EXCITATION OF MOTONEURONES BY GABA-MEDIATED PRIMARY AFFERENT DEPOLARIZATION IN THE MOUSE SPINAL-CORD INVITRO. J PHYSIOL-LONDON , 364 (JUL) P45 - P45.

DUCHEN, MR and BURTON, NR and BISCOE, TJ (1985) AN INTRACELLULAR STUDY OF THE INTERACTIONS OF N-METHYL-DL-ASPARTATE WITH KETAMINE IN THE MOUSE HIPPOCAMPAL SLICE. BRAIN RES , 342 (1) 149 - 153.

1983

BISCOE, TJ and DUCHEN, MR and PASCOE, JE (1983) GABA BENZODIAZEPINE INTERACTIONS IN THE MOUSE HIPPOCAMPAL SLICE. J PHYSIOL-LONDON , 341 (AUG) P8 - P9.

BISCOE, TJ and DUCHEN, MR and PASCOE, JE (1983) USE OF THE RML-380Z MICROCOMPUTER FOR ONLINE MEASUREMENT OF INPUT RESISTANCE OF CELLS IN THE MOUSE HIPPOCAMPAL SLICE. J PHYSIOL-LONDON , 341 (AUG) P2 - P3.

1982

BISCOE, TJ and CRUNELLI, V and DUCHEN, MR and FORDA, S (1982) THE MOUSE HIPPOCAMPAL SLICE - INTRACELLULAR-RECORDINGS FROM PYRAMIDAL NEURONS AND DENTATE GRANULE CELLS. J PHYSIOL-LONDON , 328 (JUL) P5 - P5.

1980

DUCHEN, MR and MCNEILLY, AS (1980) HYPER-PROLACTINEMIA AND LONG-TERM LACTATIONAL AMENORRHEA. CLIN ENDOCRINOL , 12 (6) 621 - 627.

This list was generated on Wed Jun 19 02:11:07 2013 BST.