Seminars and Events

Seminar Weds 10 Dec: Dr Trevor Graham - Clonal evolution of cancer

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Bloomsbury Centre for Genetic Epidemiology and Statistics seminar:

Wednesday 10th December 2014, 1-2pm, Room LG9, London School of Hygiene and Tropical Medicine

Seminar 26 Sept: Modelling rate of decline (slope) of a biomarker as a quantitative genetic trait using mixed effects models: application to loss of renal function (GFR) in type 1 diabetes

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You are invited to the following Bloomsbury Centre for Genetic Epidemiology and Statistics seminar:

Progress Educational Trust events 8 and 22 May 2014

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Progress Educational Trust will be holding the following events at UCL:

Thursday 8 May, 6:30pm 'RISK ASSESSMENT: BREAST CANCER, PREDICTION AND SCREENING' 

Short Courses September 2014

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Bloomsbury Centre for Genetic Epidemiology and Statistics will run 2 short courses in September 2014:

Population Genetics Methods and Findings - Beer & Pizza Science Evening

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Tuesday 11 February 2014, 5:00 - 7:30pm, 2nd floor seminar room, Rayne Building, UCL

Programme:

Seminar 26 November, Paul O'Reilly - Increasing statistical power in GWAS

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Seminar organised by the Bloomsbury Centre for Genetic Epidemiology and Statistics

Tuesday 26 November 2013, 4:30 - 5:30pm, Location: Taviton (16) 431, 14-16 Taviton Street (UCL)
Dr. Paul O'Reilly, Senior Lecturer, Social Genetic & Developmental Psychiatry, King's College London
Title: "Increasing statistical power in GWAS"

Bioinformatics and GO Annotation Workshop (1-2 May 2014)

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Registration for Bioinformatics and GO Annotation Workshop is now open. This 2-day course provides hands-on training in the use of GO, as well as other bioinformatics resources, such as UniProt, Ensembl, Biomart, IntAct and Cytoscape. As always this workshop is freely available to all biological or biomedical PhD and Post-Doc research scientists. If you wish to attend, please register online.

BCGES seminar - Tuesday 6 August at 4:30pm

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The next BCGES will be on Tuesday 6 August in UCL Darwin B15 (Biochemistry LT):

Title: Discovery and fine-mapping of type 2 diabetes (T2D) susceptibility loci via trans-ethnic meta-analysis.

UGI Seminar - John Overington, EBI, 2nd July at 1pm

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“ChEMBL - An Open Database of Bioactivity and Pharmacology Data for Drug Discovery"

Venue: Second Floor Seminar Room

Annotating the Genome, BCGES Annual Meeting, 11 June 2013 

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This meeting will be held in conjunction with the South England Genetic Epidemiology Group on Tuesday 11th June (11am -5pm) at John Snow LT, London School of Hygiene and Tropical Medicine.

Tue 7 May, "Beer & Pizza" Metabolism and Pharmacokinetics Science evening

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Venue: 2nd floor seminar room, Rayne building

Further details and to register visit:

- Eventbrite

UGI Seminar - John Overington, EBI, 2nd July at 1pm

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“ChEMBL - An Open Database of Bioactivity and Pharmacology Data for Drug Discovery"

Venue: Second Floor Seminar Room

EBI Roadshow at UCL, 28-30 May 2013

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The EBI will be holding a roadshow at UCL in May 2013.

The training will cover:

Tuesday 12 March, 1–2pm, Dr Garrett Hellenthal, ‘Identifying and dating historical admixture events in humans using DNA’

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Gavin de Beer LT, Anatomy Building, UCL

Abstract:

We describe a new method that uses DNA to identify historical events that have shaped present-day populations. In particular, the approach exploits modern large-scale genetic collections to unearth times in the past where two or more genetically distinct groups interacted and exchanged DNA. The method dates precisely when such events occurred, characterizes the amount of DNA exchange, and describes the genetic composition of the (perhaps extinct) groups involved.  We highlight the model’s advantages over currently available techniques in the field, including its improved parameter estimation and the additional information it contributes beyond any available methods. Our inference, based entirely on DNA, provides a powerful complement to anthropological resources, helping to resolve existing archaeological controversies, determine precisely how much DNA exchange accompanied known historical periods, and discover previously unknown events. We describe an application to data collected from 95 world-wide geographic regions, in which we characterize over 100 DNA exchange events occurring in the past 3000 years.

Progress Educational Trust's public debate-'Receiving:The Recipient Parent Perspective', 24 January 2013

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You are invited to attend the Progress Educational Trust's FREE public debate 'RECEIVING: THE RECIPIENT PARENT PERSPECTIVE' at University College London on Thursday 24 January 2013. This event is taking place from 6.30pm-8.30pm, and forms part of the Wellcome Trust supported project 'WHEN IT TAKES MORE THAN TWO'.

Course:Introduction to bioinformatics and resources and Gene Ontology, 18-19. April 

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This course aims to provide information about Gene Ontology and other bioinformatic resources, such as Ensembl and UniProt.  It will provide practical demonstrations of a number of freely available high-throughput analysis tools that can be used for the analysis of large datasets, such as those derived from proteomic or microarray methodologies. 

"Genome wide gene pathway analysis-statistical methods and applications", 11 Dec at 1pm

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Venue: LG8 (LSHTM)

Abstract:

Pathways analysis methods aim to uncover aspects of the genetic architecture of disease that might otherwise be missed when considering genetic variants in isolation.  This approach is motivated by the observation that in many cases disease states are likely to be driven by multiple genetic variants of small to moderate effect, mediated through their interaction in molecular networks or gene pathways, rather than by the effects of a few, highly penetrant mutations. In this talk I will give a brief introduction to sparse regression methods for genome wide association studies, and describe a sparse modelling approach for the identification of pathways associated with a quantitative trait.  I will also describe two application studies identifying pathways and genes associated with high-density lipoprotein levels in two Asian cohorts, and with longitudinal structural change in the brains of patients with Alzheimer's Disease.

UGI Seminar: Prof David Curtis - "25 years searching for the gene for schizophrenia", 29 Nov at 1pm

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Venue: Biochemistry LT, Darwin Building

All welcome

Journal Club: Wednesday 10 October, 1pm

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*** Human population genetics journal club ***
 Cruciform Foyer 102 Seminar Room 2

Garrett Hellenthal will present the following paper: "Ancient Admixture in Human History" by Patterson et al (2012)


All welcome

2 UGI seminars: Weds 19 Sept, 2-3pm

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VENUE: DARWIN BIOCHEMISTRY LECTURE THEATRE B15


Seminar 1:

UGI Seminar: Drug safety pharmacogenomics: challenges and opportunities, Prof Munir Pirmohamed

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Prof Munir Pirmohamed is the NHS Chair of Pharmacogenetics and Head of Dept of Molecular and Clinical Pharmacology at Liverpool University.

BCGES short courses September 2012

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Bloomsbury Centre for Genetic Epidemiology and Statistics will be running two short courses in September 2012.

Gene Ontology Annotation Workshop: 10-11 September 2012

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This workshop aims to provide information about Gene Ontology and other bioinformatic resources, such as Ensembl and UniProt.  It will provide practical demonstrations of a number of freely available high-throughput analysis tools that can be used for the analysis of large datasets, such as those derived from proteomic or microarray methodologies.


Attendees may bring in their own datasets for analysis. Annotations created during this workshop will be added to the GOA database at EBI and will be incorporated, through existing pipelines, into all of the major biological knowledgebases, such as EntrezGene, Ensembl, UniProt and GeneCards. In addition these annotations will be available for use by the majority of high-throughput analysis tools.

This event is free however registration is required.

2 July - Pipelines for analysis of next generation exome sequence data, Beer & Pizza evening

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Monday 2 July, 17:00 - 19:30
Leolin Price LT, Institute of Child Health

The event is free to attend

    * registration is required


Bloomsbury Centre for Genetic Epidemiology and Statistics Annual Scientific Meeting, 12 June, 2-6:30pm

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Venue: John Snow Lecture Theatre A, LSHTM, Keppel St

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