Software

Members of the UGI have contributed towards the following software packages:

  • LDAK – improved SNP-based heritability analysis

Software for investigating the genetic architecture of complex traits and diseases.

Website

Paper

  • Colocalisation of GWAS/eQTL signals to identify shared biological mechanisms

Compares association study p-values (e.g. from testing a biomarker), with liver or brain expression data outputting a posterior probability for a common signal within a region defined by the expression probe (200Kb upstream and downstream from the probe).

Website

Paper

  • bnlearn - Bayesian network learning

An R package for learning the graphical structure of Bayesian networks, estimating their parameters and performing some useful inference

Website

Book

  • LikeLTD - Evaluation of mixed-source, low-template DNA profiels in forensic science

An R package for computing likelihoods for DNA profile evidence, including complex mixtures and when profiles are subject to dropout.

Website

Paper

  • FastMixedModel - fast inference in linear mixed effects models

Incorporated within the MixABEL R package, within the GenABEL suite of software.

Website

Paper

  • HyperLASSO - Simultaneious analysis of genome-wide SNP data

FREGENE - simulate sequence-like data in large genomic regions and large populations. Released as part of BARGEN (Bioinformatics for the Analysis and Exploitation of Resequenced Genomes).

Website

Paper

Paper No2

  • David Balding has also been involved in the population genetics softwares HapCluster, BayesFST, Mac5 and BATWING

HapCluster

BayesFST

Mac5

BATWING

Page last modified on 01 may 14 14:00