UCL Genetics Institute (UGI)

The MSc in Pharmacogenetics and Stratified Medicine programme is offered full-time over 12 months beginning in September 2011. It is divided into three parts: compulsory core modules, optional modules and a dissertation project.

Core Modules:

• Molecular Pharmacology
• Clinical Applications of Pharmacogenetic Tests
• Drug Discovery 1
• Advanced Human Genetics 2
• Basic Statistics for Medical Sciences
• Henry Stewart's lectures on Principles of Human Genetics

Optional Modules:

• Drug Discovery 2
• Toxicology Biomarkers (new from September 2012)
• Anti-cancer drugs (new from September 2012)
• Genetics of Cardiovascular Disease
• Genetics of Neurological Disease
• Immunopharmacology
• Statistics for Interpreting Genetic Data

Dissertation

This is the practical part of the programme and will consist of an original piece of research. Assessment of these courses will be by an oral presentation and a written dissertation.

Examples of Projects

• Hereditary haemochromatosis mutation and polymorphism: investigation of of HFE and HAMP as a risk factors for CVD
• Fine scale genotyping and use of tSNPs for AFAMIN in relationship to Metabolic Syndrome and T2D and CHD risk
• Meta-analysis of interaction between APOE genotype and smoking on CHD risk
• Obesity, Infl;ammation and Oral infections: are microRNAs the missing link?
• Identification of novel urinary biomarkers of hepatic injury in the Han Wistar rat
• The role of Keap1 mutations found in lung cancer in perturbing protein-protein interactions with its binding partners

An MSc will be awarded on satisfactory completion of the compulsory modules,  optional modules and a dissertation based on an original piece of work of research (taught - 120 credits; research project - 60 credits).