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Dr Vanessa Diaz

  • Telephone:

    020 7679 3928

  • Email:

    v.diaz@ucl.ac.uk

  • Webpage:

    http://www.ucl.ac.uk/muse/

  • Address:

    413 Department of Mechanical Engineering ,
    Roberts Building, Torrington Place,
    London,
    WC1E 7JE

  • Appointments:

    Lecturer, Dept of Mechanical Engineering, Faculty of Engineering Science

Summary

Dr Vanessa Díaz obtained her degree in Mechanical Engineering from University Simon Bolivar (Venezuela), where she was awarded his MEng degree with First Class Honours. She then obtained her PhD in Automatic Control and Industrial Informatics ("très honorable avec les félicitations du jury"; the highest academic distinction awarded for doctorates in the French academic university system) from Ecole Centrale de Lille, France in 2003, her PhD work focused on lumped parameter models, simulation and optimization of cardiac dynamics. She started working in 2004 for Imagine, S.A, a consulting and software developer company (Amesim® software) in Lyon, France, in modelling and simulation of non-standard thermodynamic applications and fuel cells. In 2004, she was awarded a Marie Curie Intra-European Fellowship by the European Commission. In the Framework of her Marie Curie Fellowship, she worked as a Research Fellow in the Academic Unit of Medical Physics at the University of Sheffield from 2005 until 2007, with her research focused on the coupling of biologically-oriented lumped parameter models as boundary conditions for 3D models of cardiovascular applications, specifically, on the modelling and simulation of mechanical heart valves behaviour. Vanessa joined the department as a Lecturer in 2007.  Vanessa is currently the PI of several EU, EPSRC and Royal Society Grants and is the scientific lead of the "Multiscale Cardiovascular Engineering" (MUSE) group at UCL.  Vanessa won the "UCL Consultants Award" in 2012 for her work in the project "DISCIPULUS".

Research Summary



Vanessa’s research interests have covered different disciplines, often combined. She is interested in the development of multi-scale, multi-physics and biologically-oriented, appropriate boundary conditions for 3D models in the cardiovascular field. She is also interested in the utilization of computational tools for the design and optimization of cardiovascular devices (mechanical heart valves, stents, etc.) and on the numerical simulation of physiological systems and in the application of different modeling techniques to tackle multi-scale biological applications. Vanessa is also interested in exploring the use of optimization tools applied to the modelling and simulation of the cardiovascular system. Vanessa is leading the group MUSE "Multiscale Cardiovascular Engineering"

http://www.ucl.ac.uk/muse



Research Activities

  • Cardiovascular Modelling
  • Computational Biology
  • Computational Physiology
  • Multiscale Modelling

Recent Publications

Displaying 31 most recent publications. For the full list please visit UCL Discovery

  1. Diaz V,schievano (2013) Biomedical Imaging and Computational Modeling in Cardiovascular Disease: Patient-Specific Applications Using Numerical Models Lecture Notes in Computational Vision and Biomechanics, 4, 173 - 192.
  2. Diaz VA,Castiglione F,Merelli, E ,Lio P,Mazza C,Merskel C,Pappalardo F,Von Ammon R (2013) Physio-Environmental Sensing and Live Modeling Interactive Journal of Medical Research, 2(1). 10.2196/ijmr.2092.
  3. Bhattacharya-Ghosh, B ,Schievano, S ,Diaz, V (2012) A multi-physics and multi-scale lumped parameter model of cardiac contraction of the left ventricle: A conceptual model from the protein to the organ scale Computers in Biology and Medicine, 42(10), 982 - 992. 10.1016/j.compbiomed.2012.07.010.
  4. Coveney PV,Diaz VA,Hunter PH,Kohl P,Viceconti M (2011) The Virtual Physiological Human Interface Focus, 1, 281 - 285. 10.1098/​rsfs.2011.0020.
  5. Cosentino D,Capelli C,Pennati G,Diaz-Zuccarini V,Bonhoeffer P,Taylor AM,Schievano S (2011) Stent Fracture Prediction in Percutaneous Pulmonary Valve Implantation: A Patient-Specific Finite Element Analysis INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, 36, 288 - 293.
  6. Bhattacharya-Ghosh B,Schievano S,Diaz-Zuccarini V (2011) Integration of the Calcium Dynamics in the Excitation Contraction Coupling Process within a Multiscale Model of the Left Ventricle INTERNATIONAL CONFERENCE ON ADVANCEMENTS OF MEDICINE AND HEALTH CARE THROUGH TECHNOLOGY, 36, 266 - 269.
  7. Lawford PV,Narracott AV,McCormack K,Bisbal J,Martin C,Bijnens B,Brook B,Zachariou M,Villa I Freixa J,Kohl P,Fletcher K,Diaz-Zuccarini V (2011) Virtual physiological human: training challenges (vol 368, pg 2841, 2010) PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 369(1935), 494 - 494. 10.1098/rsta.2010.0307.
  8. Diaz-Zuccarini V,Pichardo-Almarza C (2011) On the formalization of multi-scale and multi-science processes for integrative biology INTERFACE FOCUS, 1(3), 426 - 437. 10.1098/rsfs.2010.0038.
  9. Lau KD,Diaz-Zuccarini V,Scambler P,Burriesci G (2011) Fluid-structure interaction study of the edge-to-edge repair technique on the mitral valve J BIOMECH, 44(13), 2409 - 2417. 10.1016/j.jbiomech.2011.06.030.
  10. Di Tomaso G,Diaz-Zuccarini V,Pichardo-Almarza C (2011) A Multiscale Model of Atherosclerotic Plaque Formation at Its Early Stage IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 58(12), 3460 - 3463. 10.1109/TBME.2011.2165066.
  11. Lau K,Diaz-Zuccarini V,Scambler P,Burriesci G (2010) Mitral Valve dynamics in structural and fluid-structure interaction models. Medical Engineering and Physics, 32(9-2), 1057 - 1064.
  12. Diaz-Zuccarini V,Lawford PV (2010) An in silico future for the engineering of functional tissues and organs ORGANOGENESIS, 6(4), 245 - 251. 10.4161/org6.4.13284.
  13. Diaz-Zuccarini V,Lawford PV (2010) An In-Silico Future for the Engineering of Functional Tissues and Organs Organogenesis, 6(4), 245 - 251. 10.4161/org.6.4.13284.
  14. Lawford PV,Narracott AV,McCormack K,Bisbal J,Martin C,Bijnens B,Brook B,Zachariou M,Villà I Freixa J,Kohl P,Fletcher K,Diaz-Zuccarini V (2010) Virtual Physiological Human: training challenges Philosophical Transactions of the Royal Society A, 368(1921), 2841 - 2851.
  15. Narracott AJ,Zervides C,Diaz V,Rafiroiu D,Lawford PV,Hose DR (2010) Analysis of a mechanical heart valve prosthesis and a native venous valve: Two distinct applications of FSI to biomedical applications International Journal for Numerical Methods in Biomedical Engineering, 26(3), 421 - 434.
  16. Hunter P,Van Beek H,de Bono B,Coveney P,Diaz V,Fenner J,Frangi A,Harris P,Hose DR,Kohl P,Lawford P,McCormack K,Mendes M,Omholt S,Quarteroni A,Skar J,Tegner J,Thomas SR,Tsamardinos I,Viceconti M (2010) A Vision and Strategy for the VPH in 2010 and beyond Philosophical Transactions of the Royal Society A.
  17. Diaz-Zuccarini V,Rafirou D,LeFevre J,Hose DR,Lawford PV (2009) Systemic modelling and computational physiology: The application of Bond Graph boundary conditions for 3D cardiovascular models SIMULATION MODELLING PRACTICE AND THEORY, 17(1), 125 - 136. 10.1016/j.simpat.2008.04.006.
  18. Lau KD,Diaz V,Burriesci G,Scambler P (2009) Modelling and simulation of the mitral valve under physiological and pathological conditions: a primer study. International Journal of Artificial Organs, 32(7), 400.
  19. Díaz-Zuccarini V,Narracott AJ,Burriesci G,Zervides C,Rafiroiu D,Jones D,Hose DR,Lawford PV (2009) Adaptation and development of software simulation methodologies for cardiovascular engineering: present and future challenges from an end-user perspective Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 367(1898), 2655 - 2666. 10.1098/rsta.2009.0052.
  20. Diaz V,Kofod G (2009) Researchers without Frontiers Nature, 446, 466 - 466. 10.1038/nj7134-466b.
  21. Rafiroiu D,Diaz-Zuccarini V,Narracott A,Lawford PV,Hose DR (2008) MULTI-PHYSICS & MULTI-SCALE MODELLING: CLOSURE DYNAMICS OF A BILEAFLET PROSTHETIC HEART VALVE, 41, s241. 10.1016/S0021-9290(08)70240-9.
  22. Turcu AE,Rafiroiu DV,Diaz-Zuccarini V,Narracott AJ,Hose DR,Lawford PV (2008) Investigations of the thrombogenic and cavitational potentials of a bileaflet mechanical heart valve, using ANSYS-CFX, 3, 106 - 111. 10.1109/AQTR.2008.4588892.
  23. Zervides C,Narracott AJ,Díaz-Zuccarini V,Burriesci G,Lawford PV,Hose DR (2008) The Effect of Avalvulia on Venous Haemodynamics: a Numerical Investigation Congenital Cardiology Today, 6(12), 10 - 15.
  24. Diaz-Zuccarini V,Rafiroiu D,Hose D R L,P V N,A J (2008) Multiphysics and Multiscale Simulation: Application to a Coupled Model of the Left Ventricle and a Mechanical Heart Valve International Journal for Multiscale Computational Engineering, 6(1), 65 - 76.
  25. Diaz-Zuccarini V,LeFèvre J (2007) An energetically coherent lumped parameter model of the left ventricle specially developed for educational purposes Computers in Biology and Medicine, 37(6), 774 - 784. 10.1016/j.compbiomed.2006.07.002.
  26. Díaz-Zuccarini V,Rafirou D,Hose DR,Lawford PV,Narracott AJ (2007) Multi-physics and Multi-scale Modelling in Cardiovascular Physiology: Advanced User Methods for Simulation of Biological Systems with ANSYSCFX Lecture Notes in Computer Science, 4487, 794 - 801.
  27. Diaz V (2006) Coupling a bond graph model of the left ventricle with a CFX model of the aorta: a first approach Journal of Biomechanics.
  28. Diaz-Zuccarini V,LeFevre J,Delgado M RA (2003) A model of the left ventricle: from the mechanisms of contraction to hemodynamics.
  29. Diaz-Zuccarini V (2003) Etude des conditions d'efficacite du ventricule gauche par optimisation teleonomique d'un modele de son fonctionnement.
  30. Díaz-Zuccarini V,LeFèvre J,Rahmani A,Delgado M (2002) Integrating a Bond Graph Based Model of Chemo Mechanical Coupling with Huxley's Sliding Filament Theory. ESM, 423 - 427.
  31. Hunter P,Chapman T,Coveney PV,de Bono B,Diaz V,Fenner J,Frangi AF,Harris P,Hose R,Kohl P,Lawford P,McCormack K,Mendes M,Omholt S,Quarteroni A,Shublaq N,Skår J,Stroetmann K,Tegner J,Thomas SR,Tollis I,Tsamardinos I,van Beek JHGM,Viceconti M A Vision and Strategy for the VPH: 2012 update Interface Focus, 3(2).

Biography

Dr Vanessa Díaz obtained her degree in Mechanical Engineering from University Simon Bolivar (Venezuela), where she was awarded his MEng degree with First Class Honours. She then obtained her PhD in Automatic Control and Industrial Informatics ("très honorable avec les félicitations du jury"; the highest academic distinction awarded for doctorates in the French academic university system) from Ecole Centrale de Lille, France in 2003, her PhD work focused on lumped parameter models, simulation and optimization of cardiac dynamics. She started working in 2004 for Imagine, S.A, a consulting and software developer company (Amesim® software) in Lyon, France, in modelling and simulation of non-standard thermodynamic applications and fuel cells. In 2004, she was awarded a Marie Curie Intra-European Fellowship by the European Commission. In the Framework of her Marie Curie Fellowship, she worked as a Research Fellow in the Academic Unit of Medical Physics at the University of Sheffield from 2005 until 2007, with her research focused on the coupling of biologically-oriented lumped parameter models as boundary conditions for 3D models of cardiovascular applications, specifically, on the modelling and simulation of mechanical heart valves behaviour. Vanessa joined the department as a Lecturer in 2007.  Vanessa is currently the PI of several EU, EPSRC and Royal Society Grants and is the scientific lead of the "Multiscale Cardiovascular Engineering" (MUSE) group at UCL.  Vanessa won the "UCL Consultants Award" in 2012 for her work in the project "DISCIPULUS".

Qualifications

  • 1998: Ingeniero (Engineer), Universidad de Simon Bolivar

Keywords

  • multiscale modelling, cardiovascular modelling, computational physiology