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Recent Publications

Displaying 23 most recent publications. For the full list please visit UCL Discovery

1. Man SH,Géranton SM,Hunt SP (2012) Lamina I NK1 expressing projection neurones are functional in early postnatal rats and contribute to the setting up of adult mechanical sensory thresholds. Mol Pain, 8, 35. 10.1186/1744-8069-8-35.
2. Tochiki KK,Cunningham J,Hunt SP,Géranton SM (2012) The expression of spinal methyl-CpG-binding protein 2, DNA methyltransferases and histone deacetylases is modulated in persistent pain states. Mol Pain, 8, 14. 10.1186/1744-8069-8-14.
3. Géranton SM (2012) Targeting epigenetic mechanisms for pain relief. Curr Opin Pharmacol, 12(1), 35 - 41. 10.1016/j.coph.2011.10.012.
4. Obara I,Géranton SM,Hunt SP (2012) Axonal protein synthesis: a potential target for pain relief? Curr Opin Pharmacol, 12(1), 42 - 48. 10.1016/j.coph.2011.10.005.
5. Obara I,Tochiki KK,Géranton SM,Carr FB,Lumb BM,Liu Q,Hunt SP (2011) Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice. Pain, 152(11), 2582 - 2595. 10.1016/j.pain.2011.07.025.
6. Finn DP,Roche M,Ford GK,Rea K,Olango WM,Butler RK,Harhen B,Geranton SM,Hunt SP (2010) Neurobiology of fear-induced analgesia EUROPEAN NEUROPSYCHOPHARMACOLOGY, 20, S192 - S192.
7. Downs J,Géranton SM,Bebbington A,Jacoby P,Bahi-Buisson N,Ravine D,Leonard H (2010) Linking MECP2 and pain sensitivity: the example of Rett syndrome. Am J Med Genet A, 152A(5), 1197 - 1205. 10.1002/ajmg.a.33314.
8. Géranton SM,Tochiki KK,Chiu WW,Stuart SA,Hunt SP (2010) Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway. Mol Pain, 6, 54. 10.1186/1744-8069-6-54.
9. Finn DP,Roche M,Ford GK,Rea K,Olango WM,Butler RK,Harhen B,Geranton SM,Hunt SP (2010) Neurobiology of fear-induced analgesia EUROPEAN NEUROPSYCHOPHARMACOLOGY, 20, S192 - S192.
10. Navarro-López J,Jiménez-Díaz L,Géranton SM,Ashmore JF (2009) Electrophysiological and molecular analysis of K_v7/KCNQ potassium channels in the inferior colliculus of adult guinea pig Journal of Molecular Neuroscience, 37(3), 263 - 268. 10.1007/s12031-008-9130-2.
11. Geranton SM,Jimenez-Diaz L,Torsney C,Tochiki KK,Stuart SA,Leith JL,Lumb BM,Hunt SP (2009) A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states. Journal of Neuroscience, 29, 15017 - 15027. 10.1523/JNEUROSCI.3451-09.2009.
12. Vega-Avelaira D,Géranton SM,Fitzgerald M (2009) Differential regulation of immune responses and macrophage/neuron interactions in the dorsal root ganglion in young and adult rats following nerve injury. Mol Pain, 5, 70. 10.1186/1744-8069-5-70.
13. Price TJ,Géranton SM (2009) Translating nociceptor sensitivity: the role of axonal protein synthesis in nociceptor physiology. Eur J Neurosci, 29(12), 2253 - 2263. 10.1111/j.1460-9568.2009.06786.x.
14. Jiménez-Díaz L,Géranton SM,Passmore GM,Leith JL,Fisher AS,Berliocchi L,Sivasubramaniam AK,Sheasby A,Lumb BM,Hunt SP (2008) Local translation in primary afferent fibers regulates nociception PLoS ONE, 3(4), e1961. 10.1371/journal.pone.0001961.
15. Géranton SM,Fratto V,Tochiki KK,Hunt SP (2008) Descending serotonergic controls regulate inflammation-induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn Molecular Pain, 4(1), 35. 10.1186/1744-8069-4-35.
16. Tebar LA,Géranton SM,Parsons-Perez C,Fisher AS,Bayne R,Smith AJH,Turmaine M,Perez-Luz S,Sheasby A,De Felipe C,Ruff C,Raivich G,Hunt SP (2008) Deletion of the mouse RegIIIβ (Reg2) gene disrupts ciliary neurotrophic factor signaling and delays myelination of mouse cranial motor neurons Proceedings of the National Academy of Sciences of the United States of America, 105(32), 11400 - 11405. 10.1073/pnas.0711978105.
17. Geranton SM,Morenilla-Palao C,Hunt SP (2007) A role for transcriptional repressor Methyl-CpG-binding protein 2 and plasticity-related gene serum- and glucocorticoid-inducible kinase 1 in the induction of inflammatory pain states Journal of Neuroscience, 27(23), 6163 - 6173.
18. Geranton SM,Heal DJ,Stanford SC (2004) 5-HT has contrasting effects in the frontal cortex, but not the hypothalamus, on changes in noradrenaline efflux induced by the monoamine releasing-agent, d-amphetamine, and the reuptake inhibitor, BTS 54 354 Neuropharmacology, 46, 511 - 518. 10.1016/j.neuropharm.2003.10.012.
19. Geranton SM,Heal DJ,Stanford SC (2003) Differences in the mechanisms that increase noradrenaline efflux after administration of d-amphetamine: a dual-probe microdialysis study in rat frontal cortex and hypothalamus British Journal of Pharmacology, 139(8), 1441 - 1448. 10.1038/sj.bjp.0705396.
20. Geranton SM,Heal DJ,Stanford SC (2003) Noradrenaline clearance differs in the frontal cortex and hypothalamus: a dual-probe microdialysis study in freely-moving rats Neuroscience Letters, 350(5), 157 - 160.
21. Geranton SM,Heal D,Stanford SC (2002) In vivo, dual-probe, microdialysis study of the effects of local infusion of d-amphetamine on noradrenaline efflux in rat hypothalamus and frontal cortex BRIT J PHARMACOL, 135.
22. Geranton SM,Heal DJ,Stanford SC (2002) Inhibition of 5-hydroxytryptamine synthesis increases d-amphetamine evoked efflux of noradrenaline: A dual-probe microdialysis study in the frontal cortex and the hypothalamus of freely-moving rats JOURNAL OF PSYCHOPHARMACOLOGY, 16(3), A61 - A61.
23. Geranton SM,Heal DJ,Stanford SC (2001) A dual-probe, microdialysis study of the role of alpha(2)-adrenoceptors in modulation of the effects of d-amphetamine on noradrenaline efflux in rat frontal cortex and hypothalamus MONITORING MOLECULES IN NEUROSCIENCE, 379 - 380.

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