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Dr Richard Orrell

  • Telephone:

    020 7830 2387

  • Extension:

    #6 292 x34373

  • Fax:

    020 7472 6829

  • Email:

    r.orrell@ucl.ac.uk

  • Address:

    Department of Clinical Neurosciences, UCL Institute of Neuro,
    Rowland Hill Street,
    London,
    NW3 2PF

  • Appointments:

    Senior Clinical Lecturer, Clinical Neuroscience, Institute of Neurology

Research Summary

My research theme is focussed on neuromuscular disorders, neurodegenerative disorders, and neurogenetics. Within neuromuscular disorders I am interested in motor neuron disease / amyotrophic lateral sclerosis, muscular dystrophies, neuropathies, and related conditions. Current research projects include mitochondrial function in ALS, the neurotrophic effects of mechanogrowth factor (MGF) in ALS and other disorders, and genetic analysis of ALS. In addition to laboratory research, I provide a clinical service in neuromuscular disorders, including my role as Co-Director of the Motor Neuron Disease Care and Research Centre at the National Hospital for Neurology and Neurosurgery, and motor neuron disease, muscle and nerve disorder clinics at the Royal Free Hospital. I perform muscle and nerve biopsies, and EMG, and contribute to the reporting of peripheral nerve biopsies. As co-lead for motor neuron disease in the North Thames Department of Health funded Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), I am developing a structure for clinical and other research projects. I am lead of the UCL Motor Neuron Disease Research Interest Group.

Research Activities

  • Neuromuscular and Neurodegenerative Disorders
  • Protein biomarker

Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

  1. Bartolome F,Wu H-C,Burchell VS,Preza E,Wray S,Mahoney CJ,Fox NC,Calvo A,Canosa A,Moglia C,Mandrioli J,Chiò A,Orrell RW,Houlden H,Hardy J,Abramov AY,Plun-Favreau H (2013) Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels Neuron, 78(1), 57 - 64.
  2. Al-Chalabi A,Allen C,Counsell C,Farrin A,Dickie B,Kelly J,Leigh PN,Murphy CL,Payan C,Reynolds G,Shaw P,Steen IN,Thornhill M,Waters J,Zajicek J,Shaw PJ,Young CA,Morrison KE,Dhariwal S,Hornabrook R,Savage L,Burn DJ,Khoo TK,Kelly J,Murphy CL,Dougherty A,Wijesekera L,Ellis CM,O'Hanlon K,Panicker J,Pate L,Ray P,Wyatt L,Copeland L,Ealing J,Hamdalla H,Leroi I,Murphy C,O'Keeffe F,Oughton E,Partington L,Paterson P,Rog D,Sathish A,Sexton D,Smith J,Vanek H,Dodds S,Williams TL,Clarke J,Eziefula C,Howard R,Orrell R,Sidle K,Sylvester R,Barrett W,Merritt C,Talbot K,Turner MR,Whatley C,Williams C,Williams J,Cosby C,Hanemann CO,Imam I,Phillips C,Timings L,Crawford SE,Hewamadduma C,Hibberd R,Hollinger H,McDermott C,Mills G,Rafiq M,Taylor A,Waines E,Walsh T,Addison-Jones R,Birt J,Hare M,Majid T (2013) Lithium in patients with amyotrophic lateral sclerosis (LiCALS): A phase 3 multicentre, randomised, double-blind, placebo-controlled trial The Lancet Neurology, 12(4), 339 - 345.
  3. Hobson EV,McGeachan A,Al-Chalabi A,Chandran S,Crawley F,Dick D,Donaghy C,Ealing J,Ellis CM,Gorrie G,Hanemann CO,Harrower T,Jung A,Majeed T,Malaspina A,Morrison K,Orrell RW,Pall H,Pinto A,Talbot K,Turner MR,Williams TL,Young CA,Shaw PJ,McDermott CJ (2013) Management of sialorrhoea in motor neuron disease: A survey of current UK practice. Amyotroph Lateral Scler Frontotemporal Degener. 10.3109/21678421.2013.790452.
  4. Beck J,Poulter M,Hensman D,Rohrer JD,Mahoney CJ,Adamson G,Campbell T,Uphill J,Borg A,Fratta P,Orrell RW,Malaspina A,Rowe J,Brown J,Hodges J,Sidle K,Polke JM,Houlden H,Schott JM,Fox NC,Rossor MN,Tabrizi SJ,Isaacs AM,Hardy J,Warren JD,Collinge J,Mead S (2013) Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population. Am J Hum Genet, 92(3), 345 - 353. 10.1016/j.ajhg.2013.01.011.
  5. Mok K,Laaksovirta H,Tienari PJ,Peuralinna T,Myllykangas L,Chiò A,Traynor BJ,Nalls MA,Gurunlian N,Shatunov A,Restagno G,Mora G,Nigel Leigh P,Shaw CE,Morrison KE,Shaw PJ,Al-Chalabi A,Hardy J,Orrell RW (2013) Homozygosity analysis in amyotrophic lateral sclerosis. Eur J Hum Genet. 10.1038/ejhg.2013.59.
  6. Docherty RJ,Ginsberg L,Jadoon S,Orrell RW,Bhattacharjee A (2013) TRPA1 insensitivity of human sural nerve axons after exposure to lidocaine. Pain. 10.1016/j.pain.2013.04.030.
  7. Bartolome F,Wu HC,Burchell VS,Preza E,Wray S,Mahoney CJ,Fox NC,Calvo A,Canosa A,Moglia C,Mandrioli J,Chiò A,Orrell RW,Houlden H,Hardy J,Abramov AY,Plun-Favreau H (2013) Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels. Neuron, 78(1), 57 - 64. 10.1016/j.neuron.2013.02.028.
  8. Beck J,Poulter M,Hensman D,Rohrer JD,Mahoney CJ,Adamson G,Campbell T,Uphill J,Borg A,Fratta P,Orrell RW,Malaspina A,Rowe J,Brown J,Hodges J,Sidle K,Polke JM,Houlden H,Schott JM,Fox NC,Rossor MN,Tabrizi SJ,Isaacs AM,Hardy J,Warren JD,Collinge J,Mead S (2013) Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population American Journal of Human Genetics, 92(3), 345 - 353.
  9. Orrell RW (2012) Diagnosing and managing muscular dystrophy Practitioner, 256(1754), 21 - 24.
  10. Majounie E,Renton AE,Mok K,Dopper EGP,Waite A,Rollinson S,Chiò A,Restagno G,Nicolaou N,Simon-Sanchez J,van Swieten JC,Abramzon Y,Johnson JO,Sendtner M,Pamphlett R,Orrell RW,Mead S,Sidle KC,Houlden H,Rohrer JD,Morrison KE,Pall H,Talbot K,Ansorge O,Hernandez DG,Arepalli S,Sabatelli M,Mora G,Corbo M,Giannini F,Calvo A,Englund E,Borghero G,Floris GL,Remes AM,Laaksovirta H,McCluskey L,Trojanowski JQ,Van Deerlin VM,Schellenberg GD,Nalls MA,Drory VE,Lu C-S,Yeh T-H,Ishiura H,Takahashi Y,Tsuji S,Le Ber I,Brice A,Drepper C,Williams N,Kirby J,Shaw P,Hardy J,Tienari PJ,Heutink P,Morris HR,Pickering-Brown S,Traynor BJ (2012) Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: A cross-sectional study The Lancet Neurology, 11(4), 323 - 330.
  11. Lane RJ,Roncaroli F,Charles P,McGonagle DG,Orrell RW (2012) Acetylcholine receptor antibodies in patients with genetic myopathies: clinical and biological significance. Neuromuscul Disord, 22(2), 122 - 128. 10.1016/j.nmd.2011.06.751.
  12. Mok K,Traynor BJ,Schymick J,Tienari PJ,Laaksovirta H,Peuralinna T,Myllykangas L,Chiò A,Shatunov A,Boeve BF,Boxer AL,DeJesus-Hernandez M,Mackenzie IR,Waite A,Williams N,Morris HR,Simón-Sánchez J,van Swieten JC,Heutink P,Restagno G,Mora G,Morrison KE,Shaw PJ,Rollinson PS,Al-Chalabi A,Rademakers R,Pickering-Brown S,Orrell RW,Nalls MA,Hardy J (2012) Chromosome 9 ALS and FTD locus is probably derived from a single founder. Neurobiol Aging, 33(1), 209.e3 - 209.e8. 10.1016/j.neurobiolaging.2011.08.005.
  13. Majounie E,Renton AE,Mok K,Dopper EGP,Waite A,Rollinson S,Chiò A,Restagno G,Nicolaou N,Simon-Sanchez J,van Swieten JC,Abramzon Y,Johnson JO,Sendtner M,Pamphlett R,Orrell RW,Mead S,Sidle KC,Houlden H,Rohrer JD,Morrison KE,Pall H,Talbot K,Ansorge O,Hernandez DG,Arepalli S,Sabatelli M,Mora G,Corbo M,Giannini F,Calvo A,Englund E,Borghero G,Floris GL,Remes AM,Laaksovirta H,McCluskey L,Trojanowski JQ,Van Deerlin VM,Schellenberg GD,Nalls MA,Drory VE,Lu C-S,Yeh T-H,Ishiura H,Takahashi Y,Tsuji S,Le Ber I,Brice A,Drepper C,Williams N,Kirby J,Shaw P,Hardy J,Tienari PJ,Heutink P,Morris HR,Pickering-Brown S,Traynor BJ (2012) Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: A cross-sectional study The Lancet Neurology, 11(4), 323 - 330.
  14. Majounie E,Renton AE,Mok K,Dopper EG,Waite A,Rollinson S,Chiò A,Restagno G,Nicolaou N,Simon-Sanchez J,van Swieten JC,Abramzon Y,Johnson JO,Sendtner M,Pamphlett R,Orrell RW,Mead S,Sidle KC,Houlden H,Rohrer JD,Morrison KE,Pall H,Talbot K,Ansorge O,Chromosome 9-ALS/FTD Consortium ,French research network on FTLD/FTLD/ALS ,ITALSGEN Consortium ,Hernandez DG,Arepalli S,Sabatelli M,Mora G,Corbo M,Giannini F,Calvo A,Englund E,Borghero G,Floris GL,Remes AM,Laaksovirta H,McCluskey L,Trojanowski JQ,Van Deerlin VM,Schellenberg GD,Nalls MA,Drory VE,Lu CS,Yeh TH,Ishiura H,Takahashi Y,Tsuji S,Le Ber I,Brice A,Drepper C,Williams N,Kirby J,Shaw P,Hardy J,Tienari PJ,Heutink P,Morris HR,Pickering-Brown S,Traynor BJ (2012) Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol, 11(4), 323 - 330. 10.1016/S1474-4422(12)70043-1.
  15. Orrell RW (2011) GPs have key role in managing motor neurone disease. Practitioner, 255(1743), 19 - 2.
  16. Renton AE,Majounie E,Waite A,Simón-Sánchez J,Rollinson S,Gibbs JR,Schymick JC,Laaksovirta H,van Swieten JC,Myllykangas L,Kalimo H,Paetau A,Abramzon Y,Remes AM,Kaganovich A,Scholz SW,Duckworth J,Ding J,Harmer DW,Hernandez DG,Johnson JO,Mok K,Ryten M,Trabzuni D,Guerreiro RJ,Orrell RW,Neal J,Murray A,Pearson J,Jansen IE,Sondervan D,Seelaar H,Blake D,Young K,Halliwell N,Callister JB,Toulson G,Richardson A,Gerhard A,Snowden J,Mann D,Neary D,Nalls MA,Peuralinna T,Jansson L,Isoviita VM,Kaivorinne AL,Hölttä-Vuori M,Ikonen E,Sulkava R,Benatar M,Wuu J,Chiò A,Restagno G,Borghero G,Sabatelli M,ITALSGEN Consortium ,Heckerman D,Rogaeva E,Zinman L,Rothstein JD,Sendtner M,Drepper C,Eichler EE,Alkan C,Abdullaev Z,Pack SD,Dutra A,Pak E,Hardy J,Singleton A,Williams NM,Heutink P,Pickering-Brown S,Morris HR,Tienari PJ,Traynor BJ (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron, 72(2), 257 - 268. 10.1016/j.neuron.2011.09.010.
  17. Orrell RW (2011) Facioscapulohumeral dystrophy and scapuloperoneal syndromes. Handb Clin Neurol, 101, 167 - 180. 10.1016/B978-0-08-045031-5.00013-X.
  18. Wain LV,Shrine NRG,Shaw C,Powell JF,Hardy J,Shaw P,Morrison KE,Brown RH,Orrell R,Mok B,Palmer LJ,Hui J,James AL,Musk B,Al-Chalabi A,Tobin MD (2010) The Role of Common Copy Number Variation in Amyotrophic Lateral Sclerosis (ALS) GENETIC EPIDEMIOLOGY, 34(8), 929 - 930.
  19. Lu C,Petzold A,Kalmar B,Orrell R,Malaspina A,Greensmith L (2010) Plasma neurofilament heavy chain levels as a disease biomarker in SOD1 mice., SW336.
  20. Orrell RW,Copeland S,Rose MR (2010) Scapular fixation in muscular dystrophy Cochrane Database of Systematic Reviews, Issue 1, CD003278. 10.1002/14651858.CD003278.pub2.
  21. Orrell RW (2010) What is the clinical significance of SOD1 mutations in amyotrophic lateral sclerosis? Journal of Neurology, Neurosurgery and Psychiatry, 81(5), 473.
  22. Shatunov A,Mok K,Newhouse S,Weale ME,Smith B,Vance C,Johnson L,Veldink JH,van Es MA,van den Berg LH,Robberecht W,Van Damme P,Hardiman O,Farmer AE,Lewis CM,Butler AW,Abel O,Andersen PM,Fogh I,Silani V,Chiò A,Traynor BJ,Melki J,Meininger V,Landers JE,McGuffin P,Glass JD,Pall H,Leigh PN,Hardy J,Brown RH,Powell JF,Orrell RW,Morrison KE,Shaw PJ,Shaw CE,Al-Chalabi A (2010) Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol, 9(10), 986 - 994. 10.1016/S1474-4422(10)70197-6.
  23. Scott KM,Abhinav K,Wijesekera L,Ganesalingam J,Goldstein LH,Janssen A,Dougherty A,Willey E,Stanton BR,Turner MR,Ampong MA,Sakel M,Orrell R,Howard R,Shaw CE,Nigel Leigh P,Al-Chalabi A (2010) The association between ALS and population density: A population based study. Amyotroph Lateral Scler, 11(5), 435 - 438. 10.3109/17482961003754552.
  24. Orrell RW (2010) Motor neuron disease: systematic reviews of treatment for ALS and SMA. Br Med Bull, 93, 145 - 159. 10.1093/bmb/ldp049.
  25. Kearney M,Orrell RW,Fahey M,Pandolfo M (2010) Antioxidants and other pharmacological treatment for Friedreich ataxia MOVEMENT DISORDERS, 25(7), S193 - S193.
  26. Evans RM,Harridge SDR,Velloso CP,Yang SY,Goldspink G,Orrell RW (2010) Investigation of MGF mRNA expression in patients with amyotrophic lateral sclerosis using parallel in vivo and in vitro approaches AMYOTROPH LATERAL SC, 11(1-2), 172 - 177. 10.3109/17482960903089775.
  27. Lu C,Malaspina A,Orrell R,Kalmar B,Petzold A,Greensmith L (2010) PLASMA NEUROFILAMENT HEAVY CHAIN LEVELS AS A DISEASE BIOMARKER IN THE SOD1 MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 81(11), E62 - E62. 10.1136/jnnp.2010.226340.179.
  28. Bradley LJ,Taanman JW,Kallis C,Orrell RW (2009) Increased sensitivity of myoblasts to oxidative stress in amyotrophic lateral sclerosis peripheral tissues Experimental Neurology, 218(1), 92 - 97. 10.1016/j.expneurol.2009.04.007.
  29. Chiò A,Schymick JC,Restagno G,Scholz SW,Lombardo F,Lai SL,Mora G,Fung HC,Britton A,Arepalli S,Gibbs JR,Nalls M,Berger S,Kwee LC,Oddone EZ,Ding J,Crews C,Rafferty I,Washecka N,Hernandez D,Ferrucci L,Bandinelli S,Guralnik J,Macciardi F,Torri F,Lupoli S,Chanock SJ,Thomas G,Hunter DJ,Gieger C,Wichmann HE,Calvo A,Mutani R,Battistini S,Giannini F,Caponnetto C,Mancardi GL,La BV,Valentino F,Monsurrò MR,Tedeschi G,Marinou K,Sabatelli M,Conte A,Mandrioli J,Sola P,Salvi F,Bartolomei I,Siciliano G,Carlesi C,Orrell RW,Talbot K,Simmons Z,Connor J,Pioro EP,Dunkley T,Stephan DA,Kasperaviciute D,Fisher EM,Jabonka S,Sendtner M,Beck M,Bruijn L,Rothstein J,Schmidt S,Singleton A,Hardy J,Traynor BJ (2009) A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Hum Mol Genet, 18(8), 1524 - 1532. 10.1093/hmg/ddp059.
  30. Riddoch-Contreras J,Yang SY,Dick JRT,Goldspink G,Orrell RW,Greensmith L (2009) Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in SOD1(G93A) mice Experimental Neurology, 215(2), 281 - 289. 10.1016/j.expneurol.2008.10.014.
  31. Ciccarelli O,Behrens TE,Johansen-Berg H,Talbot K,Orrell RW,Howard RS,Nunes RG,Miller DH,Matthews PM,Thompson AJ,Smith SM (2009) Investigation of white matter pathology in ALS and PLS using tract-based spatial statistics. Human Brain Mapping, 30(2), 615 - 624. 10.1002/hbm.20527.
  32. Scott KM,Abhinav K,Stanton BR,Johnston C,Turner MR,Ampong MA,Sakel M,Orrell RW,Howard R,Shaw CE,Leigh PN,Al-Chalabi A (2009) Geographical clustering of amyotrophic lateral sclerosis in South-East England: a population study. Neuroepidemiology, 32(2), 81 - 88. 10.1159/000177032.
  33. Kearney M,Orrell RW,Fahey M,Pandolfo M (2009) Antioxidants and other pharmacological treatments for Friedreich ataxia Cochrane Database of Systematic Reviews(2).
  34. Kearney M,Orrell RW,Fahey M,Pandolfo M (2009) Antioxidants and other pharmacological treatments for Friedreich ataxia Cochrane Database of Systematic Reviews, CD007791.
  35. King RHM,Nourallah M,Muddle JR,Orrell RW (2009) Ultrastructural studies of peripheral nerves in NDRG1 mutant mice Journal of the Peripheral Nervous System, 14(Supp 2), 74 - 75.
  36. Bennett DLH,Groves M,Blake J,Holton JL,King RHM,Orrell RW,Ginsberg L,Reilly MM (2008) The use of nerve and muscle biopsy in the diagnosis of vasculitis: a 5 year retrospective study Journal of Neurology, Neurosurgery and Psychiatry, 79(12), 1376 - 1381. 10.1136/jnnp.2008.151126.
  37. Sakel M,Chalabi A,Leigh N,Shaw C,Howard R,Orrell RW,Ampong M,Turner MR,Johnston C,Stanton B,Scott KM,Abhinav K (2008) Amyotrophic lateral sclerosis in South-East England: a population based study [South-East England Amyotrophic Lateral Sclerosis (SEALS) Registry]. Neurorehabilitation and Neural Repair, 22, 582.
  38. Bacsi AM,Ginsberg L,Orrell RW (2008) Reversible dysphagia in facioscapulohumeral dystrophy caused by myasthenia gravis Journal of Neurology, Neurosurgery and Psychiatry, 79(3), 358 - 358.
  39. Orrell RW,Lane RJ,Ross M (2008) A systematic review of antioxidant treatment for amyotrophic lateral sclerosis/motor neuron disease Amyotrophic Lateral Sclerosis, 9(4), 195 - 211. 10.1080/17482960801900032.
  40. Orrell RW,Lane RJM,Ross M (2007) Antioxidant treatment for amyotrophic lateral sclerosis / motor neuron disease Cochrane Database of Systematic Reviews(1).
  41. Orrell RW,Lane RJ,Ross M (2007) Antioxidant treatment for amyotrophic lateral sclerosis / motor neuron disease. Cochrane database of systematic reviews (Online)(1).
  42. Orrell RW (2007) Endocrine myopathies, 343 - 355.
  43. Orrell RW,Clarke J,Howard RS (2007) Standards of care in motor neuron disease., 74 - 88.
  44. Orrell RW,Lane RJM,Ross M (2007) Antioxidant treatment for amyotrophic lateral sclerosis / motor neuron disease. Cochrane Database of Systematic Reviews(1), CD002829. 10.1002/14651858.CD002829.pub4.
  45. Irani SR,Mathias CJ,Orrell RW (2007) Pure autonomic failure followed by amyotrophy Neurology, 68(10), 792 - 793.
  46. Orrell RW (2007) Book review. Palliative care in amyotrophic lateral sclerosis Journal of Neurology, Neurosurgery and Pschiatry, 78, 778. 10.1136/jnnp.2007.115808.
  47. King RHM,Blake J,Muddle JR,Orrell RW,Morahan G,Kalaydjieva L (2007) Pathological and electrophysiological studies of NDRG1 mutant mice JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 12, 44 - 44.
  48. Bennett DLH,Groves M,Blake J,Holton JL,King RHM,Orrell RW,Ginsberg L,Reilly MM (2007) The use of nerve and muscle biopsy in the diagnosis of vasculitis: a 5-year retrospective study of 53 cases JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 12, 9 - 10.
  49. Ates K,Yang SY,Orrell RW,Sinanan AC,Simons P,Solomon A,Beech S,Goldspink G,Lewis MP (2007) The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle. FEBS Letters, 581(14), 2727 - 2732.
  50. Orrell RW (2007) Understanding the causes of amyotrophic lateral sclerosis. New England Journal of Medicine, 357(8), 822 - 823. 10.1056/NEJMe078146.

Qualifications

  • 1996: Doctor of Medicine, To be updated
  • 1984: Diploma of Child Health, Royal College of Physicians
  • 1982: Bachelor of Medicine/Bachelor of Surgery, University of Manchester
  • 1979: Bachelor of Science, University of Manchester

Keywords

  • Ageing
  • Axon degeneration
  • Brain
  • Brain imaging
  • Brain injury
  • Cell culture
  • Charcot-Marie-Tooth disease
  • Chronic inflammatory demyelinating polyneuropathy
  • Clinical trials
  • Dementia - frontotemporal
  • Demyelination
  • Diffusion tensor imaging (DTI)
  • Disorders of neuromuscular junction transmission
  • Disorders of striated muscle
  • Electromyography
  • Electron Microscopy
  • Electrophysiology
  • Environmental toxins
  • Enzyme assays
  • Epidemiology
  • Gene expression
  • Genetic screens
  • Genetics
  • Genomic analyses
  • Genomics
  • Guillain-Barré syndrome
  • Histology
  • Image analysis
  • Imaging
  • Immunohistochemistry
  • Inflammation
  • Interneurons
  • Ion channels
  • Leukodystrophies
  • Linkage, mapping and positional cloning
  • MRNA
  • Magnetic resonance imaging (MRI)
  • Metabolic myopathies
  • MiRNA analysis
  • Mitochondria
  • Motor Neurone Disease
  • Motor control
  • Mouse
  • Movement disorders
  • Muscular dystrophy
  • Myelin
  • Myelopathies
  • Myotonia
  • Neural signalling
  • Neural stem cells
  • Neurodegeneration
  • Neurodegenerative diseases
  • Neuroendocrine
  • Neuroimaging
  • Neuromuscular Disorders and Neurodegnerative Diseases, MND/ALS, muscular dystrophy, neuropathy, genetics
  • Neuromuscular junction
  • Neuron
  • Neuropathology
  • Neuropathy
  • Neurophysiology
  • Neuroscience
  • Nitric oxide
  • Pharmacology
  • Plasticity
  • Primary progressive aphasia
  • Protein aggregation
  • Protein misfolding
  • Proteomics
  • Proteomics
  • Randomized Controlled Trials (RCTs)
  • Rehabilitation
  • Remyelination
  • Repair
  • Social Neuroscience
  • Speech
  • Spinal cord
  • Stem cells
  • Synapse
  • Transgenic mice
  • Wallerian degeneration