Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

1. Guerreiro R,Wojtas A,Bras J,Carrasquillo M,Rogaeva E,Majounie E,Cruchaga C,Sassi C,Kauwe JS,Younkin S,Hazrati L,Collinge J,Pocock J,Lashley T,Williams J,Lambert JC,Amouyel P,Goate A,Rademakers R,Morgan K,Powell J,St George-Hyslop P,Singleton A,Hardy J,Alzheimer Genetic Analysis G (2013) TREM2 variants in Alzheimer's disease N Engl J Med, 368, 117 - 127. 10.1056/NEJMoa1211851.
2. Guerreiro R,Kara E,Le Ber I,Bras J,Rohrer JD,Taipa R,Lashley T,Dupuits C,Gurunlian N,Mochel F,Warren JD,Hannequin D,Sedel F,Depienne C,Camuzat A,Golfier V,Du Boisguéheneuc F,Schottlaender L,Fox NC,Beck J,Mead S,Rossor MN,Hardy J,Revesz T,Brice A,Houlden H (2013) Genetic Analysis of Inherited Leukodystrophies: Genotype-Phenotype Correlations in the CSF1R Gene. JAMA Neurol, 1 - 9. 10.1001/jamaneurol.2013.698.
3. Guerreiro RJ,Lohmann E,Brás JM,Gibbs JR,Rohrer JD,Gurunlian N,Dursun B,Bilgic B,Hanagasi H,Gurvit H,Emre M,Singleton A,Hardy J (2013) Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement. JAMA Neurol, 70(1), 78 - 84. 10.1001/jamaneurol.2013.579.
4. Harold D,Abraham R,Hollingworth P,Sims R,Gerrish A,Hamshere ML,Pahwa JS,Moskvina V,Dowzell K,Williams A,Jones N,Thomas C,Stretton A,Morgan AR,Lovestone S,Powell J,Proitsi P,Lupton MK,Brayne C,Rubinsztein DC,Gill M,Lawlor B,Lynch A,Morgan K,Brown KS,Passmore PA,Craig D,McGuinness B,Todd S,Holmes C,Mann D,Smith AD,Love S,Kehoe PG,Hardy J,Mead S,Fox N,Rossor M,Collinge J,Maier W,Jessen F,Schürmann B,Heun R,van den Bussche H,Heuser I,Kornhuber J,Wiltfang J,Dichgans M,Frölich L,Hampel H,Hüll M,Rujescu D,Goate AM,Kauwe JS,Cruchaga C,Nowotny P,Morris JC,Mayo K,Sleegers K,Bettens K,Engelborghs S,De Deyn PP,Van Broeckhoven C,Livingston G,Bass NJ,Gurling H,McQuillin A,Gwilliam R,Deloukas P,Al-Chalabi A,Shaw CE,Tsolaki M,Singleton AB,Guerreiro R,Mühleisen TW,Nöthen MM,Moebus S,Jöckel KH,Klopp N,Wichmann HE,Carrasquillo MM,Pankratz VS,Younkin SG,Holmans PA,O'Donovan M,Owen MJ,Williams J (2013) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet, 45(6), 712. 10.1038/ng0613-712a.
5. Holmans P,Moskvina V,Jones L,Sharma M,International Parkinson's Disease Genomics Consortium ,Vedernikov A,Buchel F,Sadd M,Bras JM,Bettella F,Nicolaou N,Simón-Sánchez J,Mittag F,Gibbs JR,Schulte C,Durr A,Guerreiro R,Hernandez D,Brice A,Stefánsson H,Majamaa K,Gasser T,Heutink P,Wood NW,Martinez M,Singleton AB,Nalls MA,Hardy J,Morris HR,Williams NM (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet, 22(5), 1039 - 1049. 10.1093/hmg/dds492.
6. Holton P,Ryten M,Nalls M,Trabzuni D,Weale ME,Hernandez D,Crehan H,Gibbs JR,Mayeux R,Haines JL,Farrer LA,Pericak-Vance MA,Schellenberg GD,Alzheimer's Disease Genetics Consortium ,Ramirez-Restrepo M,Engel A,Myers AJ,Corneveaux JJ,Huentelman MJ,Dillman A,Cookson MR,Reiman EM,Singleton A,Hardy J,Guerreiro R,Apostolova LG,Arnold SE,Baldwin CT,Barber R,Barmada MM,Beach TG,Beecham GW,Beekly D,Bennett DA,Bigio EH,Bird TD,Blacker D,Boeve BF,Bowen JD,Boxer A,Burke JR,Buros J,Buxbaum JD,Cairns NJ,Cantwell LB,Cao C,Carlson CS,Carney RM,Carrasquillo MM,Carroll SL,Chui HC,Clark DG,Cotman CW,Crane PK,Crocco EA,Cruchaga C,Cummings JL,De Jager PL,DeCarli C,DeKosky ST,Demirci FY,Diaz-Arrastia R,Dick M,Dickson DW,Duara R,Ellis WG,Ertekin-Taner N,Evans D,Faber KM,Fallon KB,Farlow MR,Ferris S,Foroud TM,Frosch MP,Galasko DR,Ganguli M,Gearing M,Geschwind DH,Ghetti B,Gilbert JR,Gilman S,Giordani B,Glass JD,Goate AM,Graff-Radford NR,Green RC,Growdon JH,Hakonarson H,Hamilton RL,Harrell LE,Head E,Honig LS,Hulette CM,Hyman BT,Jarvik GP,Jicha GA,Jin LW,Jun G,Kamboh MI,Karlawish J,Karydas A,Kauwe JS,Kaye JA,Kim R,Koo EH,Kowall NW,Kramer P,Kukull WA,Lah JJ,Larson EB,Levey AI,Lieberman AP,Lopez OL,Lunetta KL,Mack WJ,Marson DC,Martin ER,Martiniuk F,Mash DC,Masliah E,McCormick WC,McCurry SM,McDavid AN,McKee AC,Mesulam M,Miller BL,Miller CA,Miller JW,Montine TJ,Morris JC,Naj AC,Nowotny P,Parisi JE,Peskind E,Petersen RC,Poon WW,Potter H,Quinn JF,Raj A,Rajbhandary RA,Raskind M,Reisberg B,Reitz C,Ringman JM,Roberson ED,Rogaeva E,Rosenberg RN,Sano M,Saykin AJ,Schneider JA,Schneider LS,Seeley WW,Shelanski ML,Smith CD,Sonnen JA,Spina S,St George-Hyslop P,Stern RA,Tanzi RE,Trojanowski JQ,Troncoso JC,Tsuang DW,Valladares O,Van Deerlin VM,Vardarajan BN,Vinters HV,Vonsattel JP,Wang LS,Weintraub S,Welsh-Bohmer KA,Williamson J,Woltjer RL,Wright CB,Younkin SG (2013) Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Ann Hum Genet, 77(2), 85 - 105. 10.1111/ahg.12000.
7. Guerreiro R,Wojtas A,Bras J,Carrasquillo M,Rogaeva E,Majounie E,Cruchaga C,Sassi C,Kauwe JS,Younkin S,Hazrati L,Collinge J,Pocock J,Lashley T,Williams J,Lambert JC,Amouyel P,Goate A,Rademakers R,Morgan K,Powell J,St George-Hyslop P,Singleton A,Hardy J,Alzheimer Genetic Analysis Group (2013) TREM2 variants in Alzheimer's disease. N Engl J Med, 368(2), 117 - 127. 10.1056/NEJMoa1211851.
8. Guerreiro RJ,Lohmann E,Brás JM,Gibbs JR,Rohrer JD,Gurunlian N,Dursun B,Bilgic B,Hanagasi H,Gurvit H,Emre M,Singleton A,Hardy J (2012) Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia-like Syndrome Without Bone Involvement. Arch Neurol, 1 - 7. 10.1001/archneurol.2013.579.
9. Bras J,Guerreiro R,Hardy J (2012) Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease. Nat Rev Neurosci, 13(7), 453 - 464. 10.1038/nrn3271.
10. Matsuki T,Zaka M,Guerreiro R,van der Brug MP,Cooper JA,Cookson MR,Hardy JA,Howell BW (2012) Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. PLoS One, 7(2), e31152. 10.1371/journal.pone.0031152.
11. Dobricic V,Stefanova E,Jankovic M,Gurunlian N,Novakovic I,Hardy J,Kostic V,Guerreiro R (2012) Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort. Neurobiol Aging, 33(7), 1481.e7 - 1481.12. 10.1016/j.neurobiolaging.2011.12.007.
12. Charlesworth G,Gandhi S,Bras JM,Barker RA,Burn DJ,Chinnery PF,Gentleman SM,Guerreiro R,Hardy J,Holton JL,Lees A,Morrison K,Sheerin UM,Williams N,Morris H,Revesz T,Wood NW (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiol Aging, 33(4), 838.e7 - 838.11. 10.1016/j.neurobiolaging.2011.11.001.
13. Sheerin UM,Charlesworth G,Bras J,Guerreiro R,Bhatia K,Foltynie T,Limousin P,Silveira-Moriyama L,Lees A,Wood N (2012) Screening for VPS35 mutations in Parkinson's disease. Neurobiol Aging, 33(4), 838.e1 - 838.e5. 10.1016/j.neurobiolaging.2011.10.032.
14. Gerrish A,Russo G,Richards A,Moskvina V,Ivanov D,Harold D,Sims R,Abraham R,Hollingworth P,Chapman J,Hamshere M,Pahwa JS,Dowzell K,Williams A,Jones N,Thomas C,Stretton A,Morgan AR,Lovestone S,Powell J,Proitsi P,Lupton MK,Brayne C,Rubinsztein DC,Gill M,Lawlor B,Lynch A,Morgan K,Brown KS,Passmore PA,Craig D,McGuinness B,Todd S,Johnston JA,Holmes C,Mann D,Smith AD,Love S,Kehoe PG,Hardy J,Mead S,Fox N,Rossor M,Collinge J,Maier W,Jessen F,Kölsch H,Heun R,Schürmann B,van den Bussche H,Heuser I,Kornhuber J,Wiltfang J,Dichgans M,Frölich L,Hampel H,Hüll M,Rujescu D,Goate AM,Kauwe JS,Cruchaga C,Nowotny P,Morris JC,Mayo K,Livingston G,Bass NJ,Gurling H,McQuillin A,Gwilliam R,Deloukas P,Davies G,Harris SE,Starr JM,Deary IJ,Al-Chalabi A,Shaw CE,Tsolaki M,Singleton AB,Guerreiro R,Mühleisen TW,Nöthen MM,Moebus S,Jöckel KH,Klopp N,Wichmann HE,Carrasquillo MM,Pankratz VS,Younkin SG,Jones L,Holmans PA,O'Donovan MC,Owen MJ,Williams J (2012) The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. J Alzheimers Dis, 28(2), 377 - 387. 10.3233/JAD-2011-110824.
15. Crehan H,Holton P,Wray S,Pocock J,Guerreiro R,Hardy J (2012) Complement receptor 1 (CR1) and Alzheimer's disease. Immunobiology, 217(2), 244 - 250. 10.1016/j.imbio.2011.07.017.
16. Guerreiro RJ,Hardy J (2012) TOMM40 association with Alzheimer disease: tales of APOE and linkage disequilibrium. Arch Neurol, 69(10), 1243 - 1244. 10.1001/archneurol.2012.1935.
17. Keller MF,Saad M,Bras J,Bettella F,Nicolaou N,Simón-Sánchez J,Mittag F,Büchel F,Sharma M,Gibbs JR,Schulte C,Moskvina V,Durr A,Holmans P,Kilarski LL,Guerreiro R,Hernandez DG,Brice A,Ylikotila P,Stefánsson H,Majamaa K,Morris HR,Williams N,Gasser T,Heutink P,Wood NW,Hardy J,Martinez M,Singleton AB,Nalls MA,International Parkinson's Disease Genomics Consortium (IPDGC) ,Wellcome Trust Case Control Consortium 2 (WTCCC2) (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet, 21(22), 4996 - 5009. 10.1093/hmg/dds335.
18. Guerreiro RJ,Hardy J (2012) TOMM40 association with Alzheimer disease: Tales of APOE and linkage disequilibrium Archives of Neurology, 69(10), 1243 - 1244.
19. Guerreiro RJ,Lohmann E,Kinsella E,Brás JM,Luu N,Gurunlian N,Dursun B,Bilgic B,Santana I,Hanagasi H,Gurvit H,Gibbs JR,Oliveira C,Emre M,Singleton A (2012) Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease. Neurobiol Aging, 33(5), 1008.e17 - 1008.e23. 10.1016/j.neurobiolaging.2011.10.009.
20. Bras J,Verloes A,Schneider SA,Mole SE,Guerreiro RJ (2012) Mutation of the parkinsonism gene ATP13A2 causes neuronal ceroid-lipofuscinosis. Hum Mol Genet, 21(12), 2646 - 2650. 10.1093/hmg/dds089.
21. Lohmann E,Guerreiro RJ,Erginel-Unaltuna N,Gurunlian N,Bilgic B,Gurvit H,Hanagasi HA,Luu N,Emre M,Singleton A (2012) Identification of PSEN1 and PSEN2 gene mutations and variants in Turkish dementia patients. Neurobiol Aging, 33(8), 1850.e17 - 1850.e27. 10.1016/j.neurobiolaging.2012.02.020.
22. Guerreiro RJ,Gustafson DR,Hardy J (2012) The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE. Neurobiol Aging, 33(3), 437 - 456. 10.1016/j.neurobiolaging.2010.03.025.
23. McNaughton D,Knight W,Guerreiro R,Ryan N,Lowe J,Poulter M,Nicholl DJ,Hardy J,Revesz T,Lowe J,Rossor M,Collinge J,Mead S (2012) Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series. Neurobiol Aging, 33(2), 426.e13 - 426.e21. 10.1016/j.neurobiolaging.2010.10.010.
24. Jones L,Holmans PA,Hamshere ML,Harold D,Moskvina V,Ivanov D,Pocklington A,Abraham R,Hollingworth P,Sims R,Gerrish A,Pahwa JS,Jones N,Stretton A,Morgan AR,Lovestone S,Powell J,Proitsi P,Lupton MK,Brayne C,Rubinsztein DC,Gill M,Lawlor B,Lynch A,Morgan K,Brown KS,Passmore PA,Craig D,McGuinness B,Todd S,Holmes C,Mann D,Smith AD,Love S,Kehoe PG,Mead S,Fox N,Rossor M,Collinge J,Maier W,Jessen F,Schürmann B,van den Bussche H,Heuser I,Peters O,Kornhuber J,Wiltfang J,Dichgans M,Frölich L,Hampel H,Hüll M,Rujescu D,Goate AM,Kauwe JS,Cruchaga C,Nowotny P,Morris JC,Mayo K,Livingston G,Bass NJ,Gurling H,McQuillin A,Gwilliam R,Deloukas P,Al-Chalabi A,Shaw CE,Singleton AB,Guerreiro R,Mühleisen TW,Nöthen MM,Moebus S,Jöckel KH,Klopp N,Wichmann HE,Rüther E,Carrasquillo MM,Pankratz VS,Younkin SG,Hardy J,O'Donovan MC,Owen MJ,Williams J (2011) Correction: genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. PLoS One, 6(2). 10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798.
25. Nalls MA,Plagnol V,Hernandez DG,Sharma M,Sheerin UM,Saad M,Simon-Sanchez J,Schulte C,Lesage S,Sveinbjornsdottir S,Arepalli S,Barker R,Ben-Shlomo Y,Berendse HW,Berg D,Bhatia K,de Bie RMA,Biffi A,Bloem B,Bochdanovits Z,Bonin M,Bras JM,Brockmann K,Brooks J,Burn DJ,Charlesworth G,Chen HL,Chinnery PF,Chong S,Clarke CE,Cookson MR,Cooper JM,Corvol JC,Counsell C,Damier P,Dartigues JF,Deloukas P,Deuschl G,Dexter DT,van Dijk KD,Dillman A,Durif F,Durr A,Edkins S,Evans JR,Foltynie T,Gao JJ,Gardner M,Gibbs JR,Goate A,Gray E,Guerreiro R,Gustafsson O,Harris C,van Hilten JJ,Hofman A,Hollenbeck A,Holton J,Hu M,Huang XM,Huber H,Hudson G,Hunt SE,Huttenlocher J,Illig T,Jonsson PV,Lambert JC,Langford C,Lees A,Lichtner P,Limousin P,Lopez G,Lorenz D,McNeill A,Moorby C,Moore M,Morris HR,Morrison KE,Mudanohwo E,O'Sullivan SS,Pearson J,Perlmutter JS,Petursson H,Pollak P,Post B,Potter S,Ravina B,Revesz T,Riess O,Rivadeneira F,Rizzu P,Ryten M,Sawcer S,Schapira A,Scheffer H,Shaw K,Shoulson I,Sidransky E,Smith C,Spencer CCA,Stefansson H,Stockton JD,Strange A,Talbot K,Tanner CM,Tashakkori-Ghanbaria A,Tison F,Trabzuni D,Traynor BJ,Uitterlinden AG,Velseboer D,Vidailhet M,Walker R,van de Warrenburg B,Wickremaratchi M,Williams N,Williams-Gray CH,Winder-Rhodes S,Stefansson K,Martinez M,Hardy J,Heutink P,Brice A,Gasser T,Singleton AB,Wood NW,Int Parkinson Dis Genomics Consort ,Wellcome Trust Case-Control Consor (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies LANCET, 377(9766), 641 - 649. 10.1016/S0140-6736(10)62345-8.
26. Hollingworth P,Harold D,Sims R,Gerrish A,Lambert JC,Carrasquillo MM,Abraham R,Hamshere ML,Pahwa JS,Moskvina V,Dowzell K,Jones N,Stretton A,Thomas C,Richards A,Ivanov D,Widdowson C,Chapman J,Lovestone S,Powell J,Proitsi P,Lupton MK,Brayne C,Rubinsztein DC,Gill M,Lawlor B,Lynch A,Brown KS,Passmore PA,Craig D,McGuinness B,Todd S,Holmes C,Mann D,Smith AD,Beaumont H,Warden D,Wilcock G,Love S,Kehoe PG,Hooper NM,Vardy ER,Hardy J,Mead S,Fox NC,Rossor M,Collinge J,Maier W,Jessen F,Rüther E,Schürmann B,Heun R,Kölsch H,van den Bussche H,Heuser I,Kornhuber J,Wiltfang J,Dichgans M,Frölich L,Hampel H,Gallacher J,Hüll M,Rujescu D,Giegling I,Goate AM,Kauwe JS,Cruchaga C,Nowotny P,Morris JC,Mayo K,Sleegers K,Bettens K,Engelborghs S,De Deyn PP,Van Broeckhoven C,Livingston G,Bass NJ,Gurling H,McQuillin A,Gwilliam R,Deloukas P,Al-Chalabi A,Shaw CE,Tsolaki M,Singleton AB,Guerreiro R,Mühleisen TW,Nöthen MM,Moebus S,Jöckel KH,Klopp N,Wichmann HE,Pankratz VS,Sando SB,Aasly JO,Barcikowska M,Wszolek ZK,Dickson DW,Graff-Radford NR,Petersen RC,Alzheimer's Disease Neuroimaging Initiative ,van Duijn CM,Breteler MM,Ikram MA,DeStefano AL,Fitzpatrick AL,Lopez O,Launer LJ,Seshadri S,CHARGE consortium ,Berr C,Campion D,Epelbaum J,Dartigues JF,Tzourio C,Alpérovitch A,Lathrop M,EADI1 consortium ,Feulner TM,Friedrich P,Riehle C,Krawczak M,Schreiber S,Mayhaus M,Nicolhaus S,Wagenpfeil S,Steinberg S,Stefansson H,Stefansson K,Snaedal J,Björnsson S,Jonsson PV,Chouraki V,Genier-Boley B,Hiltunen M,Soininen H,Combarros O,Zelenika D,Delepine M,Bullido MJ,Pasquier F,Mateo I,Frank-Garcia A,Porcellini E,Hanon O,Coto E,Alvarez V,Bosco P,Siciliano G,Mancuso M,Panza F,Solfrizzi V,Nacmias B,Sorbi S,Bossù P,Piccardi P,Arosio B,Annoni G,Seripa D,Pilotto A,Scarpini E,Galimberti D,Brice A,Hannequin D,Licastro F,Jones L,Holmans PA,Jonsson T,Riemenschneider M,Morgan K,Younkin SG,Owen MJ,O'Donovan M,Amouyel P,Williams J (2011) Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet, 43(5), 429 - 435. 10.1038/ng.803.
27. Hardy J,Guerreiro R,Wray S,Ferrari R,Momeni P (2011) The Genetics of Alzheimer's Disease and Other Tauopathies J ALZHEIMERS DIS, 23, S33 - S39.
28. Hardy J,Guerreiro R (2011) A new way APP mismetabolism can lead to Alzheimer's disease. EMBO Mol Med, 3(5), 247 - 248. 10.1002/emmm.201100139.
29. Guerreiro RJ,Hardy J (2011) Alzheimer's disease genetics: lessons to improve disease modelling. Biochem Soc Trans, 39(4), 910 - 916. 10.1042/BST0390910.
30. Plagnol V,Nalls MA,Bras JM,Hernandez DG,Sharma M,Sheerin UM,Saad M,Simon-Sanchez J,Schulte C,Lesage S,Sveinbjornsdottir S,Amouyel P,Arepalli S,Band G,Barker RA,Bellinguez C,Ben-Shlomo Y,Berendse HW,Berg D,Bhatia K,de Bie RMA,Biffi A,Bloem B,Bochdanovits Z,Bonin M,Brockmann K,Brooks J,Burn DJ,Charlesworth G,Chen HL,Chinnery PF,Chong S,Clarke CE,Cookson MR,Cooper JM,Corvol JC,Counsell C,Damier P,Dartigues JF,Deloukas P,Deuschl G,Dexter DT,van Dijk KD,Dillman A,Durif F,Durr A,Edkins S,Evans JR,Foltynie T,Freeman C,Gao JJ,Gardner M,Gibbs JR,Goate A,Gray E,Guerreiro R,Gustafsson O,Harris C,Hellenthal G,van Hilten JJ,Hofman A,Hollenbeck A,Holton J,Hu M,Huang XM,Huber H,Hudson G,Hunt SE,Huttenlocher J,Illig T,Jonsson PV,Langford C,Lees A,Lichtner P,Limousin P,Lopez G,Lorenz D,McNeill A,Moorby C,Moore M,Morris H,Morrison KE,Mudanohwo E,O'Sullivan SS,Pearson J,Pearson R,Perlmutter JS,Petursson H,Pirinen M,Pollak P,Post B,Potter S,Ravina B,Revesz T,Riess O,Rivadeneira F,Rizzu P,Ryten M,Sawcer S,Schapira A,Scheffer H,Shaw K,Shoulson I,Sidransky E,de Silva R,Smith C,Spencer CCA,Stefansson H,Steinberg S,Stockton JD,Strange A,Su Z,Talbot K,Tanner CM,Tashakkori-Ghanbaria A,Tison F,Trabzuni D,Traynor BJ,Uitterlinden AG,Vandrovcova J,Velseboer D,Vidailhet M,Vukcevic D,Walker R,van de Warrenburg B,Weale ME,Wickremaratchi M,Williams N,Williams-Gray CH,Winder-Rhodes S,Stefansson K,Martinez M,Donnelly P,Singleton AB,Hardy J,Heutink P,Brice A,Gasser T,Wood NW,WTCCC2 (2011) A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease PLOS GENET, 7(6). 10.1371/journal.pgen.1002142.
31. Renton AE,Majounie E,Waite A,Simón-Sánchez J,Rollinson S,Gibbs JR,Schymick JC,Laaksovirta H,van Swieten JC,Myllykangas L,Kalimo H,Paetau A,Abramzon Y,Remes AM,Kaganovich A,Scholz SW,Duckworth J,Ding J,Harmer DW,Hernandez DG,Johnson JO,Mok K,Ryten M,Trabzuni D,Guerreiro RJ,Orrell RW,Neal J,Murray A,Pearson J,Jansen IE,Sondervan D,Seelaar H,Blake D,Young K,Halliwell N,Callister JB,Toulson G,Richardson A,Gerhard A,Snowden J,Mann D,Neary D,Nalls MA,Peuralinna T,Jansson L,Isoviita VM,Kaivorinne AL,Hölttä-Vuori M,Ikonen E,Sulkava R,Benatar M,Wuu J,Chiò A,Restagno G,Borghero G,Sabatelli M,ITALSGEN Consortium ,Heckerman D,Rogaeva E,Zinman L,Rothstein JD,Sendtner M,Drepper C,Eichler EE,Alkan C,Abdullaev Z,Pack SD,Dutra A,Pak E,Hardy J,Singleton A,Williams NM,Heutink P,Pickering-Brown S,Morris HR,Tienari PJ,Traynor BJ (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron, 72(2), 257 - 268. 10.1016/j.neuron.2011.09.010.
32. Hardy J,Guerreiro R,Lovestone S (2011) Clusterin as an Alzheimer biomarker. Arch Neurol, 68(11), 1459 - 1460. 10.1001/archneurol.2011.1000.
33. Pearson JP,Williams NM,Majounie E,Waite A,Stott J,Newsway V,Murray A,Hernandez D,Guerreiro R,Singleton AB,Neal J,Morris HR (2011) Familial frontotemporal dementia with amyotrophic lateral sclerosis and a shared haplotype on chromosome 9p. J Neurol, 258(4), 647 - 655. 10.1007/s00415-010-5815-x.
34. Guerreiro RJ,Washecka N,Hardy J,Singleton A (2010) A thorough assessment of benign genetic variability in GRN and MAPT. Hum Mutat, 31(2), E1126 - E1140. 10.1002/humu.21152.
35. Beck JA,Poulter M,Campbell TA,Adamson G,Uphill JB,Guerreiro R,Jackson GS,Stevens JC,Manji H,Collinge J,Mead S (2010) PRNP allelic series from 19 years of prion protein gene sequencing at the MRC Prion Unit. Hum Mutat, 31(7), E1551 - E1563. 10.1002/humu.21281.
36. Guerreiro RJ,Beck J,Gibbs JR,Santana I,Rossor MN,Schott JM,Nalls MA,Ribeiro H,Santiago B,Fox NC,Oliveira C,Collinge J,Mead S,Singleton A,Hardy J (2010) Genetic variability in CLU and its association with Alzheimer's disease. PLoS One, 5(3), e9510. 10.1371/journal.pone.0009510.
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