Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

1. Pericleous C,Clarke LA,Brogan PA,Latchman DS,Isenberg DA,Ioannou Y,Giles IP,Rahman A (2013) Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome. Thromb Haemost, 109(1), 72 - 78. 10.1160/TH12-05-0346.
2. Singh N,Hughes M,Sebire N,Brogan P (2013) Takayasu arteritis in infancy. Rheumatology (Oxford). 10.1093/rheumatology/ket109.
3. Brogan P,Levin M (2013) Intravenous immunoglobulin plus corticosteroids prevent coronary artery abnormalities in Kawasaki disease. Evid Based Med. 10.1136/eb-2013-101264.
4. Eleftheriou D,Ganesan V,Hong Y,Klein NJ,Brogan PA (2012) Endothelial injury in childhood stroke with cerebral arteriopathy: a cross sectional study. Neurology.
5. Brogan PA,Foster HE (2012) The Oxford Handbook of Paediatric Rheumatology.
6. Fabbri-Arrigoni FI,Clarke L,Wang G,Charakida M,Ellins E,Halliday N,Brogan PA,Deanfield JE,Halcox JP,Klein N (2012) Levels of circulating endothelial cells and colony-forming units are influenced by age and dyslipidemia. Pediatr Res, 72(3), 299 - 304. 10.1038/pr.2012.76.
7. Rice GI,Kasher PR,Forte GMA,Mannion NM,Greenwood SM,Szynkiewicz M,Dickerson JE,Bhaskar SS,Zampini M,Briggs TA,Jenkinson EM,Bacino CA,Battini R,Bertini E,Brogan PA,Brueton LA,Carpanelli M,De Laet C,de Lonlay P,del Toro M,Desguerre I,Fazzi E,Garcia-Cazorla A,Heiberg A,Kawaguchi M,Kumar R,Lin J-PS-M,Lourenco CM,Male AM,Marques Jr W,Mignot C,Olivieri I,Orcesi S,Prabhakar P,Rasmussen M,Robinson RA,Rozenberg F,Schmidt JL,Steindl K,Tan TY,van der Merwe WG,Vanderver A,Vassallo G,Wakeling EL,Wassmer E,Whittaker E,Livingston JH,Lebon P,Suzuki T,McLaughlin PJ,Keegan LP,O'Connell MA,Lovell SC,Crow YJ (2012) Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature Nature Genetics.
8. Nistala K,Varsani H,Wittkowski H,Vogl T,Krol P,Shah V,Mamchaoui K,Brogan P,Roth J,Wedderburn LR (2012) Myeloid Related Proteins Induce Muscle Derived Inflammatory Mediators in Juvenile Dermatomyositis ARTHRITIS AND RHEUMATISM, 64(10), S715 - S716.
9. Rees L,Brogan PA,Bockenhauer D,Webb N (2012) The Oxford Handbook of Paediatric Nephrology.
10. Boulter EL,Eleftheriou D,Sebire NJ,Edelsten C,Brogan PA (2012) Inflammatory lesions of the orbit: a single paediatric rheumatology centre experience. Rheumatology (Oxford), 51(6), 1070 - 1075. 10.1093/rheumatology/ker432.
11. Hong Y,Eleftheriou D,Hussain AA,Price-Kuehne FE,Savage CO,Jayne D,Little MA,Salama AD,Klein NJ,Brogan PA (2012) Anti-neutrophil cytoplasmic antibodies stimulate release of neutrophil microparticles. J Am Soc Nephrol, 23(1), 49 - 62. 10.1681/ASN.2011030298.
12. Guerry MJ,Brogan P,Bruce IN,D'Cruz DP,Harper L,Luqmani R,Pusey CD,Salama AD,Scott DG,Savage CO,Watts RA,Jayne DR (2012) Recommendations for the use of rituximab in anti-neutrophil cytoplasm antibody-associated vasculitis. Rheumatology (Oxford), 51(4), 634 - 643. 10.1093/rheumatology/ker150.
13. Almeida B,Gleeson P,Chawla K,Brogan P (2012) Kawasaki disease: a case report and overview of symptoms, signs, investigations and treatment BRITISH JOURNAL OF HOSPITAL MEDICINE, 73(2), C26 - C28.
14. Brogan K,Eleftheriou D,Rajput K,Edelsten C,Sebire NJ,Brogan PA (2012) Tubulointerstitial nephritis, uveitis, hearing loss and vestibular failure: TINU-atypical Cogan's overlap syndrome. Rheumatology (Oxford), 51(5), 950 - 952. 10.1093/rheumatology/ker443.
15. Standing AS,Eleftheriou D,Lachmann HJ,Brogan PA (2011) Comment on: Familial Mediterranean fever caused by homozygous E148Q mutation complicated by Budd-Chiari syndrome and polyarteritis nodosa: reply. Rheumatology (Oxford), 50(7), 1349 - 1350. 10.1093/rheumatology/ker170.
16. Arulkumaran N,Jawad S,Smith SW,Harper L,Brogan P,Pusey CD,Salama AD (2011) Long- term outcome of paediatric patients with ANCA vasculitis. Pediatr Rheumatol Online J, 9, 12. 10.1186/1546-0096-9-12.
17. Hong Y,Eleftheriou D,Hussain AAK,Price-Kuehne FE,Savage CO,Jayne D,Little MA,Salama AD,Klein NJ,Brogan PA (2011) Antineutrophil cytoplasmic antibodies (ANCA) stimulate neutrophil microparticle release causing endothelial activation and increased thrombin generation. Journal of the American Society of Nephrology.
18. Brogan K,Eleftheriou D,Rajput K,Edelsten C,Brogan PA (2011) Tubulointerstitial nephritis, uveitis, hearing loss and vestibular failure: TINU-atypical Cogan’s overlap syndrome. Rheumatology.
19. Eleftheriou D,Hong Y,Klein NJ,Brogan PA (2011) Thromboembolic disease in systemic vasculitis is associated with enhanced microparticle-mediated thrombin generation. J Thromb Haemost. 10.1111/j.1538-7836.2011.04434.x..
20. Khor CC,Davila S,Shimizu C,Sheng S,Matsubara T,Suzuki Y,Newburger JW,Baker A,Burgner D,Breunis W,Kuijpers T,Wright VJ,Levin M,Hibberd ML,Burns JC,US and International Kawasaki Disease Genetics Consortia (2011) Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease. J Med Genet, 48, 467 - 472.
21. Morishita K,Rosendahl K,Brogan PA (2011) Familial Takayasu arteritis - a pediatric case and a review of the literature. Pediatr Rheumatol Online J..
22. Khor CC,Davila S,Breunis WB,Lee YC,Shimizu C,Wright VJ,Yeung RS,Tan DE,Sim KS,Wang JJ,Wong TY,Pang J,Mitchell P,Cimaz R,Dahdah N,Cheung YF,Huang GY,Yang W,Park IS,Lee JK,Wu JY,Levin M,Burns JC,Burgner D,Kuijpers TW,Hibberd ML,Hong Kong–Shanghai Kawasaki Disease Genetics Consortium ,Korean Kawasaki Disease Genetics Consortium ,Taiwan Kawasaki Disease Genetics Consortium ,International Kawasaki Disease Genetics Consortium ,US Kawasaki Disease Genetics Consortium ,Blue Mountains Eye Study (2011) Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet, 43(12), 1241 - 1246. 10.1038/ng.981.
23. Eleftheriou D,Klein NJ,Brogan PA (2011) Kawasaki Disease..
24. Brogan PA,Tizard EJ (2011) Wegener’s granulomatosis, Polyarteritis nodosa, microscopic polyangiitis, Behcets disease, and Relapsing Polychondritis..
25. Brogan P,Eleftheriou D,Dillon M (2010) Small vessel vasculitis. Pediatr Nephrol, 25(6), 1025 - 1035. 10.1007/s00467-009-1317-4.
26. Clarke LA,Hong Y,Eleftheriou D,Shah V,Arrigoni F,Klein NJ,Brogan PA (2010) Endothelial injury and repair in systemic vasculitis of the young. Arthritis Rheum, 62(6), 1770 - 1780. 10.1002/art.27418.
27. Eleftheriou D,Gerschman T,Sebire N,Woo P,Pilkington CA,Brogan PA (2010) Biologic therapy in refractory chronic non-bacterial osteomyelitis of childhood. Rheumatology (Oxford), 49(8), 1505 - 1512. 10.1093/rheumatology/keq122.
28. Eleftheriou D,Cox T,Saunders D,Klein NJ,Brogan PA,Ganesan V (2010) Investigation of childhood central nervous system vasculitis: magnetic resonance angiography versus catheter cerebral angiography. Dev Med Child Neurol, 52(9), 863 - 867. 10.1111/j.1469-8749.2009.03591.x.
29. Williams B,Neth O,Shingadia D,Dixon G,Jupp RS,Rosendahl K,Eastwood D,Klein N,Brogan P (2010) Mycobacterium kansasii causing septic arthritis and osteomyelitis in a child Pediatr Infect Dis J. 10.1097/INF.0b013e3181b78e8b.
30. Eleftheriou D,Brogan PA,Woo P (2010) Rare connective tissue disorders Paediatrics and Child Health, 20(2), 58 - 64.
31. Dillon MJ,Eleftheriou D,Brogan PA (2010) Medium-size-vessel vasculitis. Pediatr Nephrol, 25(9), 1641 - 1652. 10.1007/s00467-009-1336-1.
32. Basu N,Watts R,Bajema I,Baslund B,Bley T,Boers M,Brogan P,Calabrese L,Cid MC,Cohen-Tervaert JW,Flores-Suarez LF,Jujimoto S,de Groot K,Guillevin L,Hatemi G,Hauser T,Jayne D,Jennette C,Kallenberg CG,Kobayashi S,Little MA,Mahr A,McLaren J,Merkel PA,Ozen S,Puechal X,Rasmussen N,Salama A,Salvarani C,Savage C,Scott DG,Segelmark M,Specks U,Sunderkoetter C,Suzuki K,Tesar V,Wiik A,Yazici H,Luqmani R (2010) EULAR points to consider in the development of classification and diagnostic criteria for systemic vasculitis. Annals of Rheumatic Disease, 69(10), 1744 - 1750.
33. Brogan PA,Bagga A (2010) Leucocytoclastic vasculitis.
34. Standing A,Eleftheriou D,Lachmann H,Brogan PA (2010) Familial Mediterranean fever caused by homozygous E148Q mutation complicated by Budd-Chiari Syndrome and polyarteritis nodosa Rheumatology, In press.
35. Ruperto N,Ozen S,Pistoria A,Dolezalova P,Brogan P,Cabral DA,Cuttica R,Khubchandani R,Lovell DJ,O'Neil KM,Quartier P,Iusan SM,Filocamo G,Magalhaes CS,Unsal E,Oliveira S,Bracaglia C,Bagga A,Stanevicha V,Manzoni SM,Pratsidou P,Lepore L,Espada G,Paut IK,Zulian F,Barone P,Bircan Z,Maldonado Mdel R,Russo R,Vilca I,Tullus K,Cimaz R,Horneff G,Anton J,Garay S,Nielsen S,Barbano G,Martini A (2010) EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part I: Overall methodology and clinical characterisation Annals of the Rheumatic Diseases, 69(5), 790 - 797. 10.1136/ard.2009.116624.
36. Eleftheriou D,Melo M,Marks SD,Tullus K,Sills J,Cleary G,Dolezalova P,Ozen S,Pilkington C,Woo P,Klein N,Dillon MJ,Brogan PA (2009) Biologic therapy in primary systemic vasculitis of the young. Rheumatology (Oxford), 48(8), 978 - 986. 10.1093/rheumatology/kep148.
37. Eleftheriou D,Brogan PA (2009) Vasculitis in children. Best Pract Res Clin Rheumatol, 23(3), 309 - 323. 10.1016/j.berh.2009.02.001.
38. Muorah MR,Brogan PA,Sebire NJ,Trompeter RS,Marks SD (2009) Dense B cell infiltrates in paediatric renal transplant biopsies are predictive of allograft loss. Pediatr Transplant, 13(2), 217 - 222. 10.1111/j.1399-3046.2008.00943.x.
39. Burgner D,Davila S,Breunis WB,Ng SB,Li Y,Bonnard C,Ling L,Wright VJ,Thalamuthu A,Odam M,Shimizu C,Burns JC,Levin M,Kuijpers TW,Hibberd ML,Consortium IKDG (2009) A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. PLoS Genetics, 5(1), 1 - 15. 10.1371/journal.pgen.1000319.
40. Mukhtyar C,Brogan P,Luqmani R (2009) Cardiovascular involvement in primary systemic vasculitis Best Practice and Research Clinical Rheumatology, 23(3), 419 - 428. 10.1016/j.berh.2009.02.002.
41. Giles I,Pericleous C,Liu X,Ehsanullah J,Clarke L,Brogan P,Newton-West M,Swerlick R,Lambrianides A,Chen P,Latchman D,Isenberg D,Pierangeli S,Rahman A (2009) Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions. J Immunol, 182(8), 4836 - 4843. 10.4049/jimmunol.0804241.
42. Brogan RJ,Eleftheriou D,Gnanapragasam J,Klein NJ,Brogan PA (2009) Infliximab for the treatment of intravenous immunoglobulin resistant Kawasaki disease complicated by coronary artery aneurysms: a case report. Pediatr Rheumatol Online J, 7, 3. 10.1186/1546-0096-7-3.
43. Jones RB,Ferraro AJ,Chaudhry AN,Brogan P,Salama AD,Smith KG,Savage CO,Jayne DR (2009) A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis Arthritis Rheum, 60(7), 2156 - 2168. 10.1002/art.24637.
44. Eleftheriou D,Dillon MJ,Brogan PA (2009) Advances in childhood vasculitis. Curr Opin Rheumatol, 21(4), 411 - 418. 10.1097/BOR.0b013e32832c49f2.
45. Hall S,Brogan P,Haworth SG,Klein N (2009) Contribution of inflammation to the pathology of idiopathic pulmonary arterial hypertension in children. Thorax, 64(9), 778 - 783. 10.1136/thx.2008.106435.
46. Marhaug G,Shah V,Shroff R,Varsani H,Wedderburn LR,Pilkington CA,Brogan PA (2008) Age-dependent inhibition of ectopic calcification: a possible role for fetuin-A and osteopontin in patients with juvenile dermatomyositis with calcinosis. Rheumatology (Oxford), 47(7), 1031 - 1037. 10.1093/rheumatology/ken136.
47. Eleftheriou D,Amin T,Hook CE,Auchterlonie I,Houlsby WT,Denison A,Rosendhal K,Davidson JE,Klein N,Brogan PA (2008) Castleman's disease in childhood: a surgically curable mimic of autoimmune disease Rheumatology (Oxford), 47(9), 1435 - 1436. 10.1093/rheumatology/ken285.
48. Shroff RC,Shah V,Hiorns MP,Schoppet M,Hofbauer LC,Hawa G,Schurgers LJ,Singhal A,Merryweather I,Brogan P,Shanahan C,Deanfield J,Rees L (2008) The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not matrix Gla protein, are associated with vascular stiffness and calcification in children on dialysis. Nephrol Dial Transplant, 23(10), 3263 - 3271. 10.1093/ndt/gfn226.
49. Brogan PA,Shah V,Clarke LA,Dillon MJ,Klein N (2008) T cell activation profiles in Kawasaki syndrome. Clin Exp Immunol, 151(2), 267 - 274. 10.1111/j.1365-2249.2007.03567.x.
50. Clarke LA,Shah V,Arrigoni F,Eleftheriou D,Hong Y,Halcox J,Klein N,Brogan PA (2008) Quantitative detection of circulating endothelial cells in vasculitis: comparison of flow cytometry and immunomagnetic bead extraction. J Thromb Haemost, 6(6), 1025 - 1032. 10.1111/j.1538-7836.2008.02953.x.