Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

1. Wood-Kaczmar A,Deas E,Wood NW,Abramov AY (2013) The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease. Adv Exp Med Biol, 961, 241 - 249. 10.1007/978-1-4614-4756-6_20.
2. Cleeter MW,Chau KY,Gluck C,Mehta A,Hughes DA,Duchen M,Wood NW,Hardy J,Mark Cooper J,Schapira AH (2013) Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage. Neurochem Int, 62(1), 1 - 7. 10.1016/j.neuint.2012.10.010.
3. Koutsis G,Pandraud A,Karadima G,Panas M,Reilly MM,Floroskufi P,Wood NW,Houlden H (2013) Mutational analysis of PMP22, EGR2, LITAF and NEFL in Greek Charcot-Marie-Tooth type 1 patients Clinical Genetics, 83(4), 388 - 391.
4. Sheerin UM,Stamelou M,Charlesworth G,Shiner T,Spacey S,Valente EM,Wood NW,Bhatia KP (2013) Migraine with aura as the predominant phenotype in a family with a PRRT2 mutation. J Neurol, 260(2), 656 - 660. 10.1007/s00415-012-6747-4.
5. Holmström KM,Marina N,Baev AY,Wood NW,Gourine AV,Abramov AY (2013) Signalling properties of inorganic polyphosphate in the mammalian brain. Nat Commun, 4, 1362. 10.1038/ncomms2364.
6. LeishGEN Consortium ,Wellcome Trust Case Control Consortium 2 ,Fakiola M,Strange A,Cordell HJ,Miller EN,Pirinen M,Su Z,Mishra A,Mehrotra S,Monteiro GR,Band G,Bellenguez C,Dronov S,Edkins S,Freeman C,Giannoulatou E,Gray E,Hunt SE,Lacerda HG,Langford C,Pearson R,Pontes NN,Rai M,Singh SP,Smith L,Sousa O,Vukcevic D,Bramon E,Brown MA,Casas JP,Corvin A,Duncanson A,Jankowski J,Markus HS,Mathew CG,Palmer CN,Plomin R,Rautanen A,Sawcer SJ,Trembath RC,Viswanathan AC,Wood NW,Wilson ME,Deloukas P,Peltonen L,Christiansen F,Witt C,Jeronimo SM,Sundar S,Spencer CC,Blackwell JM,Donnelly P (2013) Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet, 45(2), 208 - 213. 10.1038/ng.2518.
7. Holmans P,Moskvina V,Jones L,Sharma M,International Parkinson's Disease Genomics Consortium ,Vedernikov A,Buchel F,Sadd M,Bras JM,Bettella F,Nicolaou N,Simón-Sánchez J,Mittag F,Gibbs JR,Schulte C,Durr A,Guerreiro R,Hernandez D,Brice A,Stefánsson H,Majamaa K,Gasser T,Heutink P,Wood NW,Martinez M,Singleton AB,Nalls MA,Hardy J,Morris HR,Williams NM (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet, 22(5), 1039 - 1049. 10.1093/hmg/dds492.
8. Hersheson J,Mencacci NE,Davis M,Macdonald N,Trabzuni D,Ryten M,Pittman A,Paudel R,Kara E,Fawcett K,Plagnol V,Bhatia KP,Medlar AJ,Stanescu HC,Hardy J,Kleta R,Wood NW,Houlden H (2012) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia. Ann Neurol. 10.1002/ana.23832.
9. Fitzgerald JC,Camprubi MD,Dunn L,Wu HC,Ip NY,Kruger R,Martins LM,Wood NW,Plun-Favreau H (2012) Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function. Cell Death Differ, 19(2), 257 - 266. 10.1038/cdd.2011.90.
10. Gardiner AR,Bhatia KP,Stamelou M,Dale RC,Kurian MA,Schneider SA,Wali GM,Counihan T,Schapira AH,Spacey SD,Valente E-M,Silveira-Moriyama L,Teive HAG,Raskin S,Sander JW,Lees A,Warner T,Kullmann DM,Wood NW,Hanna M,Houlden H (2012) PRRT2 gene mutations From paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine NEUROLOGY, 79(21), 2115 - 2121.
11. Duran R,Mencacci NE,Angeli AV,Shoai M,Deas E,Houlden H,Mehta A,Hughes D,Cox TM,Deegan P,Schapira AH,Lees AJ,Limousin P,Jarman PR,Bhatia KP,Wood NW,Hardy J,Foltynie T (2012) The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease Movement Disorders.
12. Gandhi S,Vaarmann A,Yao Z,Duchen MR,Wood NW,Abramov AY (2012) Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease. PLoS One, 7(5), e37564. 10.1371/journal.pone.0037564.
13. Cremades N,Cohen SI,Deas E,Abramov AY,Chen AY,Orte A,Sandal M,Clarke RW,Dunne P,Aprile FA,Bertoncini CW,Wood NW,Knowles TP,Dobson CM,Klenerman D (2012) Direct observation of the interconversion of normal and toxic forms of α-synuclein. Cell, 149(5), 1048 - 1059. 10.1016/j.cell.2012.03.037.
14. Lill CM,Roehr JT,McQueen MB,Kavvoura FK,Bagade S,Schjeide B-MM,Schjeide LM,Meissner E,Zauft U,Allen NC,Liu T,Schilling M,Anderson KJ,Beecham G,Berg D,Biernacka JM,Brice A,DeStefano AL,Do CB,Eriksson N,Factor SA,Farrer MJ,Foroud T,Gasser T,Hamza T,Hardy JA,Heutink P,Hill-Burns EM,Klein C,Latourelle JC,Maraganore DM,Martin ER,Martinez M,Myers RH,Nalls MA,Pankratz N,Payami H,Satake W,Scott WK,Sharma M,Singleton AB,Stefansson K,Toda T,Tung JY,Vance J,Wood NW,Zabetian CP,Young P,Tanzi RE,Khoury MJ,Zipp F,Lehrach H,Ioannidis JPA,Bertram L,Parkinson's GE,IPDGC ,Consortium PDGWAS,WTCCC2 (2012) Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database PLOS GENETICS, 8(3). 10.1371/journal.pgen.1002548.
15. Tucci A,Charlesworth G,Sheerin UM,Plagnol V,Wood NW,Hardy J (2012) Study of the genetic variability in a Parkinson's Disease gene: EIF4G1. Neurosci Lett, 518(1), 19 - 22. 10.1016/j.neulet.2012.04.033.
16. Proukakis C,Moore D,Labrum R,Wood NW,Houlden H (2012) HEREDITARY SPASTIC PARAPLEGIA CAUSED BY SPASTIN (SPAST, SPG4) MUTATIONS IS FOUND MORE OFTEN IN MALES: REPORT OF NOVEL MUTATIONS FROM ONE CENTRE, AND REVIEW OF PUBLISHED LITERATURE JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3). 10.1136/jnnp-2011-301993.115.
17. Charlesworth G,Gandhi S,Bras JM,Barker RA,Burn DJ,Chinnery PF,Gentleman SM,Guerreiro R,Hardy J,Holton JL,Lees A,Morrison K,Sheerin UM,Williams N,Morris H,Revesz T,Wood NW (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiol Aging, 33(4), 838.e7 - 838.11. 10.1016/j.neurobiolaging.2011.11.001.
18. Mittag F,Büchel F,Saad M,Jahn A,Schulte C,Bochdanovits Z,Simón-Sánchez J,Nalls MA,Keller M,Hernandez DG,Gibbs JR,Lesage S,Brice A,Heutink P,Martinez M,Wood NW,Hardy J,Singleton AB,Zell A,Gasser T,Sharma M (2012) Use of support vector machines for disease risk prediction in genome-wide association studies: Concerns and opportunities Human Mutation.
19. Tsoi LC,Spain SL,Knight J,Ellinghaus E,Stuart PE,Capon F,Ding J,Li Y,Tejasvi T,Gudjonsson JE,Kang HM,Allen MH,McManus R,Novelli G,Samuelsson L,Schalkwijk J,Ståhle M,Burden AD,Smith CH,Cork MJ,Estivill X,Bowcock AM,Krueger GG,Weger W,Worthington J,Tazi-Ahnini R,Nestle FO,Hayday A,Hoffmann P,Winkelmann J,Wijmenga C,Langford C,Edkins S,Andrews R,Blackburn H,Strange A,Band G,Pearson RD,Vukcevic D,Spencer CC,Deloukas P,Mrowietz U,Schreiber S,Weidinger S,Koks S,Kingo K,Esko T,Metspalu A,Lim HW,Voorhees JJ,Weichenthal M,Wichmann HE,Chandran V,Rosen CF,Rahman P,Gladman DD,Griffiths CE,Reis A,Kere J,Collaborative Association Study of Psoriasis (CASP) ,Genetic Analysis of Psoriasis Consortium ,Psoriasis Association Genetics Extension ,Wellcome Trust Case Control Consortium 2 ,Nair RP,Franke A,Barker JN,Abecasis GR,Elder JT,Trembath RC (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet, 44(12), 1341 - 1348. 10.1038/ng.2467.
20. Charlesworth G,Plagnol V,Holmström KM,Bras J,Sheerin UM,Preza E,Rubio-Agusti I,Ryten M,Schneider SA,Stamelou M,Trabzuni D,Abramov AY,Bhatia KP,Wood NW (2012) Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesis. Am J Hum Genet, 91(6), 1041 - 1050. 10.1016/j.ajhg.2012.10.024.
21. Keller MF,Saad M,Bras J,Bettella F,Nicolaou N,Simón-Sánchez J,Mittag F,Büchel F,Sharma M,Gibbs JR,Schulte C,Moskvina V,Durr A,Holmans P,Kilarski LL,Guerreiro R,Hernandez DG,Brice A,Ylikotila P,Stefánsson H,Majamaa K,Morris HR,Williams N,Gasser T,Heutink P,Wood NW,Hardy J,Martinez M,Singleton AB,Nalls MA,International Parkinson's Disease Genomics Consortium (IPDGC) ,Wellcome Trust Case Control Consortium 2 (WTCCC2) (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet, 21(22), 4996 - 5009. 10.1093/hmg/dds335.
22. Kilarski LL,Pearson JP,Newsway V,Majounie E,Knipe MDW,Misbahuddin A,Chinnery PF,Burn DJ,Clarke CE,Marion M-H,Lewthwaite AJ,Nicholl DJ,Wood NW,Morrison KE,Williams-Gray CH,Evans JR,Sawcer SJ,Barker RA,Wickremaratchi MM,Ben-Shlomo Y,Williams NM,Morris HR (2012) Systematic Review and UK-Based Study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease Movement Disorders, 27(12), 1522 - 1529.
23. Strange A,Riley BP,Spencer CCA,Morris DW,Pirinen M,O'Dushlaine CT,Su Z,Maher BS,Freeman C,Cormican P,Bellenguez C,Kenny EM,Band G,Wormley B,Donohoe G,Dilthey A,Moutsianas L,Quinn E,Edkins S,Judge R,Coleman K,Hunt S,Tropea D,Roche S,Cummings L,Kelleher E,McKeon P,Dinan T,McDonald C,Murphy KC,O'Callaghan E,O'Neill FA,Waddington JL,Walsh D,Giannoulatou E,Langford C,Deloukas P,Gray E,Dronov S,Potter S,Pearson R,Vukcevic D,Tashakkori-Ghanbaria A,Blackwell JM,Bramon E,Brown MA,Casas JP,Duncanson A,Jankowski J,Markus HS,Mathew CG,Palmer CNA,Plomin R,Rautanen A,Sawcer SJ,Trembath RC,Viswanathan AC,Wood NW,Stone J,Scolnick E,Purcell S,Sklar P,Ripke S,Walters J,Owen MJ,O'Donovan MC,Peltonen L,McVean G,Kendler KS,Gill M,Donnelly P,Corvin A,Conso ISG,Consortium SGENE,Psychiat SWG,Consor WTCC (2012) Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia BIOLOGICAL PSYCHIATRY, 72(8), 620 - 628. 10.1016/j.biopsych.2012.05.035.
24. Gardiner AR,Bhatia KP,Stamelou M,Dale RC,Kurian MA,Schneider SA,Wali GM,Counihan T,Schapira AH,Spacey SD,Valente EM,Silveira-Moriyama L,Teive HA,Raskin S,Sander JW,Lees A,Warner T,Kullmann DM,Wood NW,Hanna M,Houlden H (2012) PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. Neurology, 79(21), 2115 - 2121. 10.1212/WNL.0b013e3182752c5a.
25. Gegg ME,Burke D,Heales SJ,Cooper JM,Hardy J,Wood NW,Schapira AH (2012) Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains Ann.Neurol., 72(3), 455 - 463. 10.1002/ana.23614.
26. Stamelou M,Mencacci NE,Cordivari C,Batla A,Wood NW,Houlden H,Hardy J,Bhatia KP (2012) Myoclonus-dystonia syndrome due to tyrosine hydroxylase deficiency. Neurology, 79(5), 435 - 441. 10.1212/WNL.0b013e318261714a.
27. Plagnol V,Curtis J,Epstein M,Mok KY,Stebbings E,Grigoriadou S,Wood NW,Hambleton S,Burns SO,Thrasher AJ,Kumararatne D,Doffinger R,Nejentsev S (2012) A robust model for read count data in exome sequencing experiments and implications for copy number variant calling. Bioinformatics, 28(21), 2747 - 2754. 10.1093/bioinformatics/bts526.
28. Plun-Favreau H,Burchell VS,Holmström KM,Yao Z,Deas E,Cain K,Fedele V,Moisoi N,Campanella M,Miguel Martins L,Wood NW,Gourine AV,Abramov AY (2012) HtrA2 deficiency causes mitochondrial uncoupling through the F₁F₀-ATP synthase and consequent ATP depletion. Cell Death Dis, 3, e335. 10.1038/cddis.2012.77.
29. Sailer A,Scholz SW,Gibbs JR,Tucci A,Johnson JO,Wood NW,Plagnol V,Hummerich H,Ding J,Hernandez D,Hardy J,Federoff HJ,Traynor BJ,Singleton AB,Houlden H (2012) Exome sequencing in an SCA14 family demonstrates its utility in diagnosing heterogeneous diseases. Neurology, 79(2), 127 - 131. 10.1212/WNL.0b013e31825f048e.
30. Simón-Sánchez J,Kilarski LL,Nalls MA,Martinez M,Schulte C,Holmans P,Gasser T,Hardy J,Singleton AB,Wood NW,Brice A,Heutink P,Williams N,Morris HR (2012) Cooperative genome-wide analysis shows increased homozygosity in early onset Parkinson's Disease PLoS ONE, 7(3).
31. Koutsis G,Pemble S,Sweeney MG,Paudel R,Wood NW,Panas M,Kladi A,Houlden H (2012) Analysis of spinocerebellar ataxias due to expanded triplet repeats in Greek patients with cerebellar ataxia. J Neurol Sci, 318(1-2), 178 - 180. 10.1016/j.jns.2012.03.019.
32. International Stroke Genetics Consortium (ISGC) ,Wellcome Trust Case Control Consortium 2 (WTCCC2) ,Bellenguez C,Bevan S,Gschwendtner A,Spencer CC,Burgess AI,Pirinen M,Jackson CA,Traylor M,Strange A,Su Z,Band G,Syme PD,Malik R,Pera J,Norrving B,Lemmens R,Freeman C,Schanz R,James T,Poole D,Murphy L,Segal H,Cortellini L,Cheng YC,Woo D,Nalls MA,Müller-Myhsok B,Meisinger C,Seedorf U,Ross-Adams H,Boonen S,Wloch-Kopec D,Valant V,Slark J,Furie K,Delavaran H,Langford C,Deloukas P,Edkins S,Hunt S,Gray E,Dronov S,Peltonen L,Gretarsdottir S,Thorleifsson G,Thorsteinsdottir U,Stefansson K,Boncoraglio GB,Parati EA,Attia J,Holliday E,Levi C,Franzosi MG,Goel A,Helgadottir A,Blackwell JM,Bramon E,Brown MA,Casas JP,Corvin A,Duncanson A,Jankowski J,Mathew CG,Palmer CN,Plomin R,Rautanen A,Sawcer SJ,Trembath RC,Viswanathan AC,Wood NW,Worrall BB,Kittner SJ,Mitchell BD,Kissela B,Meschia JF,Thijs V,Lindgren A,Macleod MJ,Slowik A,Walters M,Rosand J,Sharma P,Farrall M,Sudlow CL,Rothwell PM,Dichgans M,Donnelly P,Markus HS (2012) Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet, 44(3), 328 - 333. 10.1038/ng.1081.
33. Koutsis G,Pandraud A,Polke JM,Wood NW,Panas M,Karadima G,Houlden H (2012) Novel peripheral myelin protein 22 (PMP22) micromutations associated with variable phenotypes in Greek patients with Charcot-Marie-Tooth disease. Brain, 135(Pt 8), e217 - 6. 10.1093/brain/aws034.
34. McNeill A,Duran R,Proukakis C,Bras J,Hughes D,Mehta A,Hardy J,Wood NW,Schapira AH (2012) Hyposmia and cognitive impairment in Gaucher disease patients and carriers. Mov Disord, 27(4), 526 - 532. 10.1002/mds.24945.
35. Koutsis G,Karadima G,Pandraud A,Sweeney MG,Paudel R,Houlden H,Wood NW,Panas M (2012) Genetic screening of Greek patients with Huntington’s disease phenocopies identifies an SCA8 expansion. J Neurol, 259(9), 1874 - 1878. 10.1007/s00415-012-6430-9.
36. Kojovic M,Sheerin UM,Rubio-Agusti I,Saha A,Bras J,Gibbons V,Palmer R,Houlden H,Hardy J,Wood NW,Bhatia KP (2012) Young-onset parkinsonism due to homozygous duplication of α-synuclein in a consanguineous family. Mov Disord, 27(14), 1827 - 1829. 10.1002/mds.25199.
37. Abramov AY,Gegg M,Grunewald A,Wood NW,Klein C,Schapira AH (2011) Bioenergetic consequences of PINK1 mutations in Parkinson disease. PLoS One, 6(10), e25622. 10.1371/journal.pone.0025622.
38. Devine MJ,Plun-Favreau H,Wood NW (2011) Parkinson's disease and cancer: two wars, one front. Nat Rev Cancer, 11(11), 812 - 823. 10.1038/nrc3150.
39. Plagnol V,Nalls MA,Bras JM,Hernandez DG,Sharma M,Sheerin UM,Saad M,Simon-Sanchez J,Schulte C,Lesage S,Sveinbjornsdottir S,Amouyel P,Arepalli S,Band G,Barker RA,Bellinguez C,Ben-Shlomo Y,Berendse HW,Berg D,Bhatia K,de Bie RMA,Biffi A,Bloem B,Bochdanovits Z,Bonin M,Brockmann K,Brooks J,Burn DJ,Charlesworth G,Chen HL,Chinnery PF,Chong S,Clarke CE,Cookson MR,Cooper JM,Corvol JC,Counsell C,Damier P,Dartigues JF,Deloukas P,Deuschl G,Dexter DT,van Dijk KD,Dillman A,Durif F,Durr A,Edkins S,Evans JR,Foltynie T,Freeman C,Gao JJ,Gardner M,Gibbs JR,Goate A,Gray E,Guerreiro R,Gustafsson O,Harris C,Hellenthal G,van Hilten JJ,Hofman A,Hollenbeck A,Holton J,Hu M,Huang XM,Huber H,Hudson G,Hunt SE,Huttenlocher J,Illig T,Jonsson PV,Langford C,Lees A,Lichtner P,Limousin P,Lopez G,Lorenz D,McNeill A,Moorby C,Moore M,Morris H,Morrison KE,Mudanohwo E,O'Sullivan SS,Pearson J,Pearson R,Perlmutter JS,Petursson H,Pirinen M,Pollak P,Post B,Potter S,Ravina B,Revesz T,Riess O,Rivadeneira F,Rizzu P,Ryten M,Sawcer S,Schapira A,Scheffer H,Shaw K,Shoulson I,Sidransky E,de Silva R,Smith C,Spencer CCA,Stefansson H,Steinberg S,Stockton JD,Strange A,Su Z,Talbot K,Tanner CM,Tashakkori-Ghanbaria A,Tison F,Trabzuni D,Traynor BJ,Uitterlinden AG,Vandrovcova J,Velseboer D,Vidailhet M,Vukcevic D,Walker R,van de Warrenburg B,Weale ME,Wickremaratchi M,Williams N,Williams-Gray CH,Winder-Rhodes S,Stefansson K,Martinez M,Donnelly P,Singleton AB,Hardy J,Heutink P,Brice A,Gasser T,Wood NW,WTCCC2 (2011) A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease PLOS GENET, 7(6). 10.1371/journal.pgen.1002142.
40. Nalls MA,Plagnol V,Hernandez DG,Sharma M,Sheerin UM,Saad M,Simon-Sanchez J,Schulte C,Lesage S,Sveinbjornsdottir S,Arepalli S,Barker R,Ben-Shlomo Y,Berendse HW,Berg D,Bhatia K,de Bie RMA,Biffi A,Bloem B,Bochdanovits Z,Bonin M,Bras JM,Brockmann K,Brooks J,Burn DJ,Charlesworth G,Chen HL,Chinnery PF,Chong S,Clarke CE,Cookson MR,Cooper JM,Corvol JC,Counsell C,Damier P,Dartigues JF,Deloukas P,Deuschl G,Dexter DT,van Dijk KD,Dillman A,Durif F,Durr A,Edkins S,Evans JR,Foltynie T,Gao JJ,Gardner M,Gibbs JR,Goate A,Gray E,Guerreiro R,Gustafsson O,Harris C,van Hilten JJ,Hofman A,Hollenbeck A,Holton J,Hu M,Huang XM,Huber H,Hudson G,Hunt SE,Huttenlocher J,Illig T,Jonsson PV,Lambert JC,Langford C,Lees A,Lichtner P,Limousin P,Lopez G,Lorenz D,McNeill A,Moorby C,Moore M,Morris HR,Morrison KE,Mudanohwo E,O'Sullivan SS,Pearson J,Perlmutter JS,Petursson H,Pollak P,Post B,Potter S,Ravina B,Revesz T,Riess O,Rivadeneira F,Rizzu P,Ryten M,Sawcer S,Schapira A,Scheffer H,Shaw K,Shoulson I,Sidransky E,Smith C,Spencer CCA,Stefansson H,Stockton JD,Strange A,Talbot K,Tanner CM,Tashakkori-Ghanbaria A,Tison F,Trabzuni D,Traynor BJ,Uitterlinden AG,Velseboer D,Vidailhet M,Walker R,van de Warrenburg B,Wickremaratchi M,Williams N,Williams-Gray CH,Winder-Rhodes S,Stefansson K,Martinez M,Hardy J,Heutink P,Brice A,Gasser T,Singleton AB,Wood NW,Int Parkinson Dis Genomics Consort ,Wellcome Trust Case-Control Consor (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies LANCET, 377(9766), 641 - 649. 10.1016/S0140-6736(10)62345-8.
41. Spencer CCA,Plagnol V,Strange A,Gardner M,Paisan-Ruiz C,Band G,Barker RA,Bellenguez C,Bhatia K,Blackburn H,Blackwell JM,Bramon E,Brown MA,Brown MA,Burn D,Casas JP,Chinnery PF,Clarke CE,Corvin A,Craddock N,Deloukas P,Edkins S,Evans J,Freeman C,Gray E,Hardy J,Hudson G,Hunt S,Jankowski J,Langford C,Lees AJ,Markus HS,Mathew CG,McCarthy MI,Morrison KE,Palmer CNA,Pearson JP,Peltonen L,Pirinen M,Plomin R,Potter S,Rautanen A,Sawcer SJ,Su Z,Trembath RC,Viswanathan AC,Williams NW,Morris HR,Donnelly P,Wood NW,UK Parkinson's Dis Consortium ,Wellcome Trust Case Control Consor (2011) Dissection of the genetics of Parkinson's disease identifies an additional association 5 ' of SNCA and multiple associated haplotypes at 17q21 HUM MOL GENET, 20(2), 345 - 353. 10.1093/hmg/ddq469.
42. Deas E,Wood NW,Plun-Favreau H (2011) Mitophagy and Parkinson's disease: the PINK1-parkin link. Biochim Biophys Acta, 1813(4), 623 - 633. 10.1016/j.bbamcr.2010.08.007.
43. Deas E,Plun-Favreau H,Gandhi S,Desmond H,Kjaer S,Loh SH,Renton AE,Harvey RJ,Whitworth AJ,Martins LM,Abramov AY,Wood NW (2011) PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet, 20(5), 867 - 879. 10.1093/hmg/ddq526.
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