Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

1. Dashwood MR,Tsui JC (2013) 'No-touch' saphenous vein harvesting improves graft performance in patients undergoing coronary artery bypass surgery: a journey from bedside to bench. Vascul Pharmacol, 58(3), 240 - 250. 10.1016/j.vph.2012.07.008.
2. Wang R,Löhr CV,Fischer K,Dashwood WM,Greenwood JA,Ho E,Williams DE,Ashktorab H,Dashwood MR,Dashwood RH (2012) Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer International Journal of Cancer.
3. Dashwood MR,Loesch A (2012) Inducible Nitric Oxide Synthase and Vein Graft Performance in Patients Undergoing Coronary Artery Bypass Surgery: Physiological or Pathophysiological Role? Curr Vasc Pharmacol.
4. Dashwood MR (2012) Distension of the saphenous vein during graft preparation: markers of inflammation or endothelium? Ann Thorac Surg, 94(6), 2177 - 2178. 10.1016/j.athoracsur.2012.04.132.
5. Dashwood MR,Loizidou M (2012) Determination of cell-specific receptor binding using a combination of immunohistochemistry and in vitro autoradiography: relevance to therapeutic receptor targeting in cancer. Methods Mol Biol, 878, 137 - 147. 10.1007/978-1-61779-854-2_9.
6. Knowles JP,Shi-Wen X,Haque SU,Bhalla A,Dashwood MR,Yang S,Taylor I,Winslet MC,Abraham DJ,Loizidou M (2012) Endothelin-1 stimulates colon cancer adjacent fibroblasts. Int J Cancer, 130(6), 1264 - 1272. 10.1002/ijc.26090.
7. Dashwood MR,Dooley A,Shi-Wen X,Abraham DJ,Dreifaldt M,Souza DS (2011) Perivascular fat-derived leptin: a potential role in improved vein graft performance in coronary artery bypass surgery. Interact Cardiovasc Thorac Surg, 12(2), 170 - 173. 10.1510/icvts.2010.247874.
8. Dreifaldt M,Souza DSR,Loesch A,Muddle JR,Karlsson MG,Filbey D,Bodin L,Norgren L,Dashwood MR (2011) The "no-touch'' harvesting technique for vein grafts in coronary artery bypass surgery preserves an intact vasa vasorum J THORAC CARDIOV SUR, 141(1), 145 - 150. 10.1016/j.jtcvs.2010.02.005.
9. Dashwood MR,Crump A,Shi-Wen X,Loesch A (2011) Identification of neuronal nitric oxide synthase (nNOS) in human penis: a potential role of reduced neuronally-derived nitric oxide in erectile dysfunction. Curr Pharm Biotechnol, 12(9), 1316 - 1321.
10. Lohsiriwat V,Scholefield JH,Dashwood MR,Wilson VG (2011) Pharmacological characteristics of endothelin receptors on sheep rectal blood vessels PHARMACOL RES, 63(6), 490 - 495. 10.1016/j.phrs.2011.02.010.
11. Dashwood MR,Loesch A (2010) Endothelin-1 as a neuropeptide: neurotransmitter or neurovascular effects? J Cell Commun Signal, 4(1), 51 - 62. 10.1007/s12079-009-0073-3.
12. Tsui JCS,Shi-wen X,Mehdizadeh A,Joshi D,Dashwood MR,Lawrence D,Baker DM (2010) Raised asymmetric dimethylarginine (ADMA) in ischaemic skeletal muscle BRITISH JOURNAL OF SURGERY, 97, 39 - 39.
13. Dashwood MR,Loesch A (2009) The saphenous vein as a bypass conduit: the potential role of vascular nerves in graft performance. Curr Vasc Pharmacol, 7(1), 47 - 57.
14. Dashwood MR,Savage K,Tsui JC,Dooley A,Shaw SG,Fernández Alfonso MS,Bodin L,Souza DS (2009) Retaining perivascular tissue of human saphenous vein grafts protects against surgical and distension-induced damage and preserves endothelial nitric oxide synthase and nitric oxide synthase activity. J Thorac Cardiovasc Surg, 138(2), 334 - 340. 10.1016/j.jtcvs.2008.11.060.
15. Dashwood MR (2009) Endothelin-1 and vein graft occlusion in patients undergoing bypass surgery. Eur J Clin Invest, 39 Suppl 2, 78 - 87. 10.1111/j.1365-2362.2009.02124.x.
16. Loesch A,Dashwood MR (2009) On the sympathetic innervation of the human greater saphenous vein: relevance to clinical practice. Curr Vasc Pharmacol, 7(1), 58 - 67.
17. Pimenta D,Haque S,Heetun M,Dashwood M,Shiwen W,Farooqui N,Abraham D,Loizidou M (2009) The Endothelin Axis in Drug Sensitive and Multidrug Resistant Bladder Cancer Cells Br J Surg, 97(6), 27 - 27.
18. Dashwood MR,Souza DSR,Fernandez-Alfonso MS (2008) Re: Perivascular tissue of internal thoracic artery releases potent nitric oxide and prostacyclin-independent anticontractile factor EUR J CARDIO-THORAC, 33(6), 1161 - 1162. 10.1016/j.ejcts.2008.03.021.
19. Tsui JCS,Baker D (2008) Current State of Medical Therapies for Peripheral Vascular Disease, 139 - 149. 10.1007/978-1-84628-919-4_11.
20. Baker D,Denton C (2008) Vascular Complications of Systemic Sclerosis: A Molecular Perspective, 119 - 127. 10.1007/978-1-84628-919-4_9.
21. Loizidou M (2008) Endothelin-1 promoting actions in the growth and angiogenesis of solid cancers., 187 - 196.
22. (2008) Vascular Complications in Human Disease: Mechanisms and Consequences, i - 251. 10.1007/978-1-84628-919-4.
23. Tsui JCS,Baker DM,Shaw SG,Shi-Wen X,Dashwood MR (2008) Nitric oxide synthase in critically ischaemic muscle and alterations in isoform expression during revascularization surgery British Journal of Surgery, 95(1), 72 - 79. 10.1002/bjs.5910.
24. Loesch A,Dashwood MR,Fernandez-Alfonso MS (2007) Improved saphenous vein graft patency for coronary artery bypass grafting: "No-touch" harvesting or "dissection without touching"? J THORAC CARDIOV SUR, 134(3), 819 - 820. 10.1016/j.jtcvs.2007.04.045.
25. Dashwood MR,Dooley A,Shi-Wen X,Abraham DJ,Souza DS (2007) Does periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery? J Vasc Res, 44(3), 175 - 181. 10.1159/000099833.
26. Dashwood MR,Loesch A (2007) Surgical damage of the saphenous vein and graft patency The Journal of Thoracic and Cardiovascular Surgery, 133(1), 274 - 275. 10.1016/j.jtcvs.2006.09.029.
27. Loizidou M,Hoosein M,Knowles J,Xu S,Grigoriades A,Dashwood M,Abraham D,Taylor I (2007) ET-1 promotes desmoplasia in human colorectal fibroblasts European Journal of Surgical Oncology, 33(9), 1105.
28. Hoosein MM,Dashwood MR,Dawas K,Ali HMMDA,Grant K,Savage F,Taylor I,Loizidou M (2007) Altered endothelin receptor subtypes in colorectal cancer European Journal of Gastroenterology and Hepatology, 19(9), 775 - 782. 10.1097/MEG.0b013e3282c563de.
29. Xu SW,Renzoni EA,Kennedy L,Howat S,Chen YL,Pearson JD,Bou-Gharios G,Dashwood MR,du Bois RM,Black CM,Denton CP,Abraham DJ,Leask A (2007) Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts MATRIX BIOL, 26(8), 625 - 632. 10.1016/j.matbio.2007.06.003.
30. Dashwood MR,Tsui JC (2006) The effect of acute ischemia on ET-1 and its receptors in patients with underlying chronic ischemia of the lower limb. Exp Biol Med (Maywood), 231(6), 802 - 805.
31. Xu SW,Rodriguez-Pascual F,Lamas S,Holmes A,Howat S,Pearson JD,Dashwood MR,du Bois RM,Denton CP,Black CM,Abraham DJ,Leask A (2006) Constitutive ALKS-independent C-jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: Evidence of an autocrine endothelin loop operating through the endothelin A and B receptors MOL CELL BIOL, 26(14), 5518 - 5527. 10.1128/MCB.00625-06.
32. Knowles J,Loizidou M,Dashwood M,Abraham D,Xu S,Taylor I (2006) Endothelin-1 stimulates colorectal cancer adjacent-fibroblasts European Journal of Surgical Oncology, 32, 54.
33. Loesch A,Dashwood MR,Souza DSR (2006) Does the method of harvesting the saphenous vein for coronary artery bypass surgery affect venous smooth muscle cells? iNOS immunolabelling and ultrastructural findings International Journal of Surgery, 4(1), 20 - 29. 10.1016/j.ijsu.2005.11.002.
34. Souza DSR,Johansson B,Bojo L,Karlsson R,Geijer H,Filbey D,Bodin L,Arbeus M,Dashwood MR (2006) Harvesting the saphenous vein with surrounding tissue for CABG provides long-term graft patency comparable to the left internal thoracic artery: Results of a randomized longitudinal trial The Journal of Thoracic and Cardiovascular Surgery, 132(2), 373 - U75.
35. Dashwood M,Loesch A,Dooley A,Shi-Wen X,Abraham D,Johansson B,Souza DSR (2005) Coronary artery bypass surgery (CABG), vein graft failure and nitric oxide (NO)..
36. Loesch A,Gajkowska B,Dashwood MR,Fioretto ET,Gagliardo KM,de Lima AR,Ribeiro AACM (2005) Endothelin-1 and endothelin receptors in the basilar artery of the capybara Journal of Molecular Histology, 36(1-2), 25 - 34. 10.1007/s10735-004-2912-0.
37. Dashwood MR,Savage K,Dooley A,Shi-Wen X,Abraham DJ,Souza DS (2005) Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production. Ann Thorac Surg, 80(3), 939 - 944. 10.1016/j.athoracsur.2005.03.042.
38. Loesch A,Dashwood MR,Souza DSR (2005) Are iNOS and ET-1 induced and co-localised in damaged smooth muscle cells of saphenous vein harvested for CABG?.
39. Vasilakis V,Dashwood MR,Souza DSR,Loesch A (2005) Human saphenous vein and coronary bypass surgery: scanning electron microscopy of conventional and 'no-touch' vein grafts Vascular Disease Prevention, 1, 133 - 139.
40. Loesch A,Dashwood MR,Souza DSR (2005) Is venous smooth muscle affected by harvesting procedure for coronary artery bypass surgery? iNOS and cell-to-cell communication.
41. Loesch A,Dashwood MR,Souza DSR (2005) Injured smooth muscle cells of saphenous vein during harvesting for CABG express immunoreactive ET-1: ultrastructural features.
42. Dashwood MR,Anand R,Dooley A,Karlsson M,Filbey D,Souza DSR (2004) Improved vein graft patency using a 'no-touch' technique is due to preserved endothelial nitric oxide synthase Journal of Molecular and Cellular Cardiology, 37(1), 220 - 221.
43. Dashwood MR,Anand R,Loesch A,Souza DSR (2004) Hypothesis: A potential role for the vasa vasorum in the maintenance of vein graft patency Angiology, 55(4), 385 - 395.
44. Hoosein MM,Dashwood M,Grant K,Savage F,Loizidou M,Taylor I (2004) Endothelin receptor profiles in colorectal cancer British Journal of Surgery, 91(9), 1231 - 1231.
45. Wan S,Yim APC,Johnson JL,Shukla N,Angelini GD,Smith FCT,Dashwood MR,Jeremy JY (2004) The endothelin 1(A) receptor antagonist BSF 302146 is a potent inhibitor of neointimal and medial thickening in porcine saphenous vein-carotid artery interposition grafts The Journal of Thoracic and Cardiovascular Surgery, 127(5), 1317 - 1322.
46. Dashwood MR,Anand R,Souza DSR (2004) Endothelial NOS plays an important role in the improved patency of a novel vein graft method of coronary artery bypass surgery298 Nitric Oxide, 11(1), 58 - 58.
47. Ahmed SR,Johansson BL,Karlsson MG,Souza DSR,Dashwood MR,Loesch A (2004) Human saphenous vein and coronary bypass surgery: ultrastructural aspects of conventional and "no-touch" vein graft preparations Histology and Histopathology, 19(2), 421 - 433.
48. Tsui JCS,Baker DM,Biecker E,Shaw S,Dashwood MR (2004) Altered endothelin-1 levels in acute lower limb ischemia and reperfusion ANGIOLOGY, 55(5), 533 - 539.
49. Mumtaz FH,Dashwood MR,Khan MA,Thompson CS,Mikhailidis DP,Morgan RJ (2004) Down-regulation of nitric oxide synthase in the diabetic rabbit kidney: potential relevance to the early pathogenesis of diabetic nephropathy Current Medical Research and Opinion, 20(1), 1 - 6.
50. Dashwood M,Anand R,Loesch A,Souza D (2004) Surgical trauma and vein graft failure: Further evidence for a role of ET-1 in graft occlusion Journal of Cardiovascular Pharmacology, 44, S16 - S19.