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Dr Laura Silveira Moriyama

  • Email:

    laura.moriyama@ucl.ac.uk

  • Webpage:

    http://www.ucl.ac.uk/rlweston-inst/

  • Address:

    Reta Lila Weston Institute of Neurological Studies 1 Wakefield Street,
    London,
    WC1N 1PJ

  • Appointments:

    Senior Clinical Research Associate, Molecular Neuroscience, Institute of Neurology
    UCL Clinical Teaching Fellow UCL Distance Learning Diploma in Clinical Neurology, IoN Administration, Institute of Neurology

Research Activities

  • A systematic investigation into the pathogenesis and course of Parkinson's syndrome

Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

  1. Silveira-Moriyama L,Gardiner AR,Meyer E,King MD,Smith M,Rakshi K,Parker A,Mallick AA,Brown R,Vassallo G,Jardine PE,Guerreiro MM,Lees AJ,Houlden H,Kurian MA (2013) Clinical features of childhood-onset paroxysmal kinesigenic dyskinesia with PRRT2 gene mutations Developmental Medicine and Child Neurology.
  2. Rajan S,Parsons L,Lees AJ,Silveira-Moriyama L (2013) Availability of olfactory bulb: Experience from a british Brain Bank | Disponibilidade de bulbos olfatórios em um banco de cérebro britânico: A experiência do Square Brain Bank Arquivos de Neuro-Psiquiatria, 71(2), 110 - 112.
  3. Doherty KM,Silveira-Moriyama L,Parkkinen L,Healy DG,Farrell M,Mencacci NE,Ahmed Z,Brett FM,Hardy J,Quinn N,Counihan TJ,Lynch T,Fox ZV,Revesz T,Lees AJ,Holton JL (2013) Parkin Disease: A Clinicopathologic Entity? JAMA Neurol, 1 - 9. 10.1001/jamaneurol.2013.172.
  4. Munhoz RP,Teive HA,Eleftherohorinou H,Coin LJ,Lees AJ,Silveira-Moriyama L (2013) Demographic and motor features associated with the occurrence of neuropsychiatric and sleep complications of Parkinson's disease. J Neurol Neurosurg Psychiatry. 10.1136/jnnp-2012-304440.
  5. Rajan S,Bandopadhyay R,Kingsbury A,Ayling H,Sterlacci W,Poewe W,Maier H,Ezquerro M-TH,Lees AJ,Revesz T,Silveira-Moriyama L (2013) Using the anterior olfactory nucleus to study Lewy pathology in olfactory structures NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 39, 49 - 50.
  6. Silveira-Moriyama L,Gardiner AR,Meyer E,King MD,Smith M,Rakshi K,Parker A,Mallick AA,Brown R,Vassallo G,Jardine PE,Guerreiro MM,Lees AJ,Houlden H,Kurian MA (2013) Clinical features of childhood-onset paroxysmal kinesigenic dyskinesia with PRRT2 gene mutations Developmental Medicine and Child Neurology, 55(4), 327 - 334.
  7. Doherty KM,Silveira-Moriyama L,Parkkinen L,Healy DG,Farrell M,Mencacci NE,Ahmed Z,Brett FM,Hardy J,Quinn N,Counihan TJ,Lynch T,Fox ZV,Revesz T,Lees AJ,Holton JL (2013) Parkin disease - a clinicopathological entity? NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 39, 11 - 12.
  8. Petrovic IN,Martin-Bastida A,Massey L,Ling H,O'Sullivan SS,Williams DR,Holton JL,Revesz T,Ironside JW,Lees AJ,Silveira-Moriyama L (2013) MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsy. J Neurol, 260(4), 1031 - 1036. 10.1007/s00415-012-6752-7.
  9. Rajan S,Parsons L,Lees AJ,Silveira-Moriyama L (2013) Availability of olfactory bulb: experience from a British Brain Bank. Arq Neuropsiquiatr, 71(2), 110 - 112.
  10. Doherty KM,Davagnanam I,Molloy S,Silveira-Moriyama L,Lees AJ (2013) Pisa syndrome in Parkinson's disease: a mobile or fixed deformity? J Neurol Neurosurg Psychiatry. 10.1136/jnnp-2012-304700.
  11. Xiromerisiou G,Houlden H,Sailer A,Silveira-Moriyama L,Hardy J,Lees AJ (2012) Identical twins with Leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease. Mov Disord, 27(10), 1323. 10.1002/mds.24924.
  12. Noyce AJ,Bestwick JP,Silveira-Moriyama L,Hawkes CH,Giovannoni G,Lees AJ,Schrag A (2012) Meta-analysis of early nonmotor features and risk factors for Parkinson disease Annals of Neurology, 72(6), 893 - 901.
  13. Morales-Briceño H,Rodríguez-Violante M,Cervantes-Arriaga A,Irani SR,Lees AJ,Silveira-Moriyama L (2012) Opsoclonus myoclonus syndrome associated with GQ1b antibodies. Mov Disord, 27(13), 1615 - 1616. 10.1002/mds.25169.
  14. Doherty KM,Silveira-Moriyama L,Giladi N,Bhatia KP,Parton M,Lees AJ (2012) Camptocormia: don't forget muscle disease in the movement disorder clinic. J Neurol, 259(8), 1752 - 1754. 10.1007/s00415-012-6448-z.
  15. Glass P,Lees A,Bacellar A,Zijlmans J,Katzenschlager R,Silveira-Moriyama L (2012) Clinical Features of Vascular Parkinsonism in Pathologically Confirmed Cases NEUROLOGY, 78.
  16. Moscovich, M ,Munhoz, RP ,Teive, H ,Raskin, S ,Carvalho, MDJ ,Barbosa, ER ,Ranvaud, R ,Liu, J ,McFarland, K ,Ashizawa, T ,Lees, AJ ,Silveira Moriyama L (2012) Olfactory impairment in familial ataxias Journal of Neurology, Neurosurgery and Psychiatry, 83(10), 970 - 974. 10.1136/jnnp-2012-302770.
  17. Moscovich M,Munhoz RP,Teive H,Raskin S,Carvalho MDJ,Barbosa ER,Ranvaud R,Liu J,McFarland K,Ashizawa T,Lees AJ,Silveira-Moriyama L (2012) Olfactory impairment in familial ataxias Journal of Neurology, Neurosurgery and Psychiatry.
  18. Doherty KM,Noyce AJ,Silveira-Moriyama L,Nisbet A,Quinn N,Lees AJ (2012) Familial camptocormia: from dystonia to myopathy. J Neurol Neurosurg Psychiatry, 83(3), 350 - 351. 10.1136/jnnp.2011.246561.
  19. Sheerin UM,Charlesworth G,Bras J,Guerreiro R,Bhatia K,Foltynie T,Limousin P,Silveira-Moriyama L,Lees A,Wood N (2012) Screening for VPS35 mutations in Parkinson's disease. Neurobiol Aging, 33(4), 838.e1 - 838.e5. 10.1016/j.neurobiolaging.2011.10.032.
  20. Noyce AJ,Silveira-Moriyama L,Gilpin P,Ling H,Howard R,Lees AJ (2012) Severe dysphagia as a presentation of Parkinson's disease. Mov Disord, 27(3), 457 - 458. 10.1002/mds.24006.
  21. Silveira-Moriyama L,Lees AJ (2012) Tricks of the trade | Pulo do gato Arquivos de Neuro-Psiquiatria, 70(4), 245 - 245.
  22. Stockner H,Schwingenschuh P,Djamshidian A,Silveira-Moriyama L,Katschnig P,Seppi K,Dickson J,Edwards MJ,Lees AJ,Poewe W,Bhatia KP (2012) Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease? Mov Disord, 27(9), 1182 - 1185. 10.1002/mds.25102.
  23. Noyce A,Bestwick J,Hawkes CH,Knowles CH,Hardy J,Lees AJ,Silveira-Moriyama L,Giovannoni G,Schrag A (2012) AN ALGORITHM TO IDENTIFY INDIVIDUALS AT HIGH-RISK OF PARKINSON'S DISEASE IN THE COMMUNITY JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3). 10.1136/jnnp-2011-301993.162.
  24. Noyce A,Silveira-Moriyama L,Lees AJ,Schrag A,Bestwick J,Hawkes CH,Giovannoni G,Hardy J,Knowles CH (2012) A PILOT STUDY OF AN ALGORITHM DESIGNED TO IDENTIFY PARKINSON'S DISEASE IN THE EARLY, NON-MOTOR PHASE JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3). 10.1136/jnnp-2011-301993.161.
  25. Xiromerisiou G,Houlden H,Sailer A,Silveira-Moriyama L,Hardy J,Lees AJ (2012) Identical twins with Leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease Movement Disorders, 27(10), 1323 - 1323.
  26. Noyce AJ,Bestwick JP,Silveira-Moriyama L,Hawkes CH,Giovannoni G,Lees AJ,Schrag A (2012) Meta-analysis of early nonmotor features and risk factors for Parkinson disease Annals of Neurology.
  27. Glass PG,Lees AJ,Bacellar A,Zijlmans J,Katzenschlager R,Silveira-Moriyama L (2012) The clinical features of pathologically confirmed vascular Parkinsonism Journal of Neurology, Neurosurgery and Psychiatry, 83(10), 1027 - 1029.
  28. Doherty KM,Silveira-Moriyama L,Giladi N,Bhatia KP,Parton M,Lees AJ (2012) Camptocormia: Don't forget muscle disease in the movement disorder clinic Journal of Neurology, 259(8), 1752 - 1754.
  29. Gardiner AR,Bhatia KP,Stamelou M,Dale RC,Kurian MA,Schneider SA,Wali GM,Counihan T,Schapira AH,Spacey SD,Valente EM,Silveira-Moriyama L,Teive HA,Raskin S,Sander JW,Lees A,Warner T,Kullmann DM,Wood NW,Hanna M,Houlden H (2012) PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. Neurology, 79(21), 2115 - 2121. 10.1212/WNL.0b013e3182752c5a.
  30. Gardiner AR,Bhatia KP,Stamelou M,Dale RC,Kurian MA,Schneider SA,Wali GM,Counihan T,Schapira AH,Spacey SD,Valente E-M,Silveira-Moriyama L,Teive HAG,Raskin S,Sander JW,Lees A,Warner T,Kullmann DM,Wood NW,Hanna M,Houlden H (2012) PRRT2 gene mutations From paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine NEUROLOGY, 79(21), 2115 - 2121.
  31. Glass PG,Lees AJ,Mathias C,Mason L,Best C,Williams DR,Katzenschlager R,Silveira-Moriyama L (2012) Olfaction in pathologically proven patients with multiple system atrophy Movement Disorders, 27(2), 327 - 328.
  32. Noyce AJ,Bestwick J,Hawkes CH,Knowles CH,Hardy J,Lees AJ,Silveira-Moriyama L,Giovannoni G,Schrag A (2011) An algorithm to identify individuals at high-risk of Parkinson's disease in the community MOVEMENT DISORDERS, 26, S54 - S55.
  33. Ahmed Z,Doherty K,Silveira-Moriyama L,Bandopadhyay R,Lashley T,Newcombe J,O'sullivan SS,Wroe S,De Silva R,Holton JL,Lees AJ,Revesz T (2011) Clinicopathological comparison of globular glial tauopathies presenting with motor neuron disease or frontotemporal dementia: An emerging group of 4-repeat tauopathies MOVEMENT DISORDERS, 26, S328 - S329.
  34. Petrovic IN,Martin-Bastida A,Massey L,Ling H,O'sullivan SS,Williams DR,Revesz T,Lees AJ,Silveira-Moriyama L (2011) Creutzfeldt Jacob disease presenting as progressive supranuclear palsy MOVEMENT DISORDERS, 26, S344 - S344.
  35. Höglinger, GU ,Melhem NM,Dickson DW,Sleiman PM,Wang LS,Klei L,Rademakers R,DE SILVA H,Litvan I,Riley DE,van Swieten JC,Heutink P,Wszolek ZK,Uitti RJ,Vandrovcova J,Hurtig HI,Gross RG,Maetzler W,Goldwurm S,Tolosa E,Borroni B,Pastor P,Albin RL,Alonso E,Antonini A,Apfelbacher M,Arnold SE,Avila J,Beach TG,Beecher S,Berg D,Bird TD,Bogdanovic N,Boon AJ,Bordelon Y,Brice A,Budka H,Canesi M,Chiu WZ,Cilia R,Colosimo C,De Deyn PP,de Yebenes JG,Kaat LD,Duara R,Durr A,Engelborghs S,Fabbrini G,Finch NA,Flook R,Frosch MP,Gaig C,Galasko DR,Gasser T,Gearing M,Geller ET,Ghetti B,Graff-Radford NR,Grossman M,Hall DA,Hazrati LN,Höllerhage M,Jankovic J,Juncos JL,Karydas A,Kretschmar HA,Leber I,Lee VM,Lieberman AP,Lyons KE,Mariani C,Masliah E,Massey LA,McLean CA,Meucci N,Miller BL,Mollenhauer B,Möller JC,Morris HR,Morris C,O'Sullivan SS,Oertel W,Ottaviani D,Padovani A,Pahwa R,Pezzoli G,Pickering-Brown S,Poewe W,Rabano A,Rajput A,Reich SG,Respondek G,Roeber S,Rohrer JD,Ross OA,Rossor MN,Sacilotto G,Seeley WW,Seppi K,Silveira-Moriyama L,Spina S,Srulijes K,St George-Hyslop P,Stamelou M,Standaert DG,Tesei S,Tourelotte WW,Trenkwalder C,Troakes C,Trojanowski JQ,Troncoso JC,Van Deerlin VM,Vonsattel JP,Wenning GK,White CL,Winter P,Zarow C,Zecchinelli AL,Cantwell LB,Han MR,Dillman A,van der Brug MP,Gibbs JR,Cookson MR,Hernandez DG,Singleton AB,Farrer MJ,Yu CE,Golbe LI,Revesz T,Hardy J,Lees AJ,Devlin B,Hakonarson H,Müller U,Schellenberg GD (2011) Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy Nature Genetics, 43(7), 699 - 705. 10.1038/ng.859.
  36. Silveira-Moriyama L,Yip HLK,Kearney S,Revesz T,Lees A (2011) Parkinsonism without Pathological Abnormality NEUROLOGY, 76(9), A40 - A41.
  37. Kearney SJ,Yip H,Lees AJ,Revesz T,Silveira-Moriyama L (2011) Parkinsonism without pathological explanation MOVEMENT DISORDERS, 26, S339 - S339.
  38. Ahmed Z,Doherty K,Silveira-Moriyama L,Bandopadhyay R,Lashley T,Mamais A,Hondhamuni G,Wray S,Newcombe J,O'Sullivan SS,Wroe S,de Silva R,Holton JL,Lees AJ,Revesz T (2011) Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: An emerging group of 4-repeat tauopathies Acta Neuropathologica.
  39. Ahmed Z,Doherty K,Silveira-Moriyama L,Bandopadhyay R,Lashley T,Mamais A,Hondhamuni G,Newcombe J,O'Sullivan SS,Wroe S,De Silva R,Holton JL,Lees AJ,Revesz T (2011) GLOBULAR GLIAL TAUOPATHIES: AN EMERGING GROUP OF 4-REPEAT TAUOPATHIES PRESENTING WITH MOTOR NEURON DISEASE OR FRONTOTEMPORAL DEMENTIA EUROPEAN JOURNAL OF NEUROLOGY, 18, 22 - 22.
  40. Andrade PGG,Less AJ,Silveira-Moriyama L (2011) Hyposmia in neurological diseases: A clinico-pathological study MOVEMENT DISORDERS, 26, S337 - S338.
  41. Doherty KM,van de Warrenburg BP,Peralta MC,Silveira-Moriyama L,Azulay JP,Gershanik OS,Bloem BR (2011) Postural deformities in Parkinson's disease. Lancet Neurol, 10(6), 538 - 549. 10.1016/S1474-4422(11)70067-9.
  42. Vincos GB,Testi PA,Evans AH,Lees AJ,Silveira-Moriyama L (2011) Smell loss and diet changes in Parkinson's disease MOVEMENT DISORDERS, 26, S201 - S201.
  43. Doherty KM,Silveira-Moriyama L,Davagnanam I,Molloy S,Lees AJ (2011) Spinal changes underlying postural deformity in Parkinson's disease MOVEMENT DISORDERS, 26, S240 - S241.
  44. Silveira-Moriyama L,Lees AJ (2011) Up with the lark: a panoptic view of Parkinson disease. Neurology, 77(4), 310 - 311. 10.1212/WNL.0b013e318227065d.
  45. Rodríguez-Violante M,Lees AJ,Cervantes-Arriaga A,Corona T,Silveira-Moriyama L (2011) Use of smell test identification in Parkinson's disease in Mexico: a matched case-control study. Mov Disord, 26(1), 173 - 176. 10.1002/mds.23354.
  46. Djamshidian A,Jha A,O'Sullivan SS,Silveira-Moriyama L,Jacobson C,Brown P,Lees A,Averbeck BB (2010) Risk and learning in impulsive and nonimpulsive patients with Parkinson's disease Movement Disorders, 25(13), 2203 - 2210.
  47. Djamshidian A,Jha A,O'Sullivan SS,Silveira-Moriyama L,Jacobson C,Brown P,Lees A,Averbeck BB (2010) Risk and learning in impulsive and nonimpulsive patients with Parkinson's disease. Mov Disord, 25(13), 2203 - 2210. 10.1002/mds.23247.
  48. Yip HLK,Lees AJ,Revesz T,Silveira-Moriyama L (2010) The pathological substrate for clinically diagnosed Parkinson's disease MOVEMENT DISORDERS, 25(7), S368 - S368.
  49. Silveira-Moriyama L,Hughes G,Church A,Ayling H,Williams DR,Petrie A,Holton J,Revesz T,Kingsbury A,Morris HR,Burn DJ,Lees AJ (2010) Hyposmia in progressive supranuclear palsy. Mov Disord, 25(5), 570 - 577. 10.1002/mds.22688.
  50. Schwingenschuh P,Ruge D,Edwards MJ,Terranova C,Katschnig P,Carrillo F,Silveira-Moriyama L,Schneider SA,Kägi G,Palomar FJ,Talelli P,Dickson J,Lees AJ,Quinn N,Mir P,Rothwell JC,Bhatia KP (2010) Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: a clinical and electrophysiological study. Mov Disord, 25(5), 560 - 569. 10.1002/mds.23019.

Qualifications

  • 2009: Doctor of Philosophy, University College London
  • 2003: Specialist, University of Sao Paulo
  • 1999: Doctor of Medicine, University of Sao Paulo