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Dr Gavin Charlesworth

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Research Activities

  • A systematic investigation into the pathogenesis and course of Parkinson's syndrome
  • psychosocial research in dementia

Recent Publications

Displaying 11 most recent publications. For the full list please visit UCL Discovery

  1. Sheerin UM,Stamelou M,Charlesworth G,Shiner T,Spacey S,Valente EM,Wood NW,Bhatia KP (2013) Migraine with aura as the predominant phenotype in a family with a PRRT2 mutation. J Neurol, 260(2), 656 - 660. 10.1007/s00415-012-6747-4.
  2. Rubio-Agusti I,Pareés I,Kojovic M,Stamelou M,Saifee TA,Charlesworth G,Sheerin UM,Edwards MJ,Bhatia KP (2013) Tremulous cervical dystonia is likely to be familial: Clinical characteristics of a large cohort. Parkinsonism Relat Disord, 19(6), 634 - 638. 10.1016/j.parkreldis.2013.02.017.
  3. Charlesworth G,Wood NW (2012) Mutations in Nuclear Genes That Affect Mitochondrial Function in Parkinson’s Disease.
  4. Tucci A,Charlesworth G,Sheerin UM,Plagnol V,Wood NW,Hardy J (2012) Study of the genetic variability in a Parkinson's Disease gene: EIF4G1. Neurosci Lett, 518(1), 19 - 22. 10.1016/j.neulet.2012.04.033.
  5. Charlesworth G,Plagnol V,Holmström KM,Bras J,Sheerin UM,Preza E,Rubio-Agusti I,Ryten M,Schneider SA,Stamelou M,Trabzuni D,Abramov AY,Bhatia KP,Wood NW (2012) Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesis. Am J Hum Genet, 91(6), 1041 - 1050. 10.1016/j.ajhg.2012.10.024.
  6. Charlesworth G,Gandhi S,Bras JM,Barker RA,Burn DJ,Chinnery PF,Gentleman SM,Guerreiro R,Hardy J,Holton JL,Lees A,Morrison K,Sheerin UM,Williams N,Morris H,Revesz T,Wood NW (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiol Aging, 33(4), 838.e7 - 838.11. 10.1016/j.neurobiolaging.2011.11.001.
  7. Sheerin UM,Charlesworth G,Bras J,Guerreiro R,Bhatia K,Foltynie T,Limousin P,Silveira-Moriyama L,Lees A,Wood N (2012) Screening for VPS35 mutations in Parkinson's disease. Neurobiol Aging, 33(4), 838.e1 - 838.e5. 10.1016/j.neurobiolaging.2011.10.032.
  8. Plagnol V,Nalls MA,Bras JM,Hernandez DG,Sharma M,Sheerin UM,Saad M,Simon-Sanchez J,Schulte C,Lesage S,Sveinbjornsdottir S,Amouyel P,Arepalli S,Band G,Barker RA,Bellinguez C,Ben-Shlomo Y,Berendse HW,Berg D,Bhatia K,de Bie RMA,Biffi A,Bloem B,Bochdanovits Z,Bonin M,Brockmann K,Brooks J,Burn DJ,Charlesworth G,Chen HL,Chinnery PF,Chong S,Clarke CE,Cookson MR,Cooper JM,Corvol JC,Counsell C,Damier P,Dartigues JF,Deloukas P,Deuschl G,Dexter DT,van Dijk KD,Dillman A,Durif F,Durr A,Edkins S,Evans JR,Foltynie T,Freeman C,Gao JJ,Gardner M,Gibbs JR,Goate A,Gray E,Guerreiro R,Gustafsson O,Harris C,Hellenthal G,van Hilten JJ,Hofman A,Hollenbeck A,Holton J,Hu M,Huang XM,Huber H,Hudson G,Hunt SE,Huttenlocher J,Illig T,Jonsson PV,Langford C,Lees A,Lichtner P,Limousin P,Lopez G,Lorenz D,McNeill A,Moorby C,Moore M,Morris H,Morrison KE,Mudanohwo E,O'Sullivan SS,Pearson J,Pearson R,Perlmutter JS,Petursson H,Pirinen M,Pollak P,Post B,Potter S,Ravina B,Revesz T,Riess O,Rivadeneira F,Rizzu P,Ryten M,Sawcer S,Schapira A,Scheffer H,Shaw K,Shoulson I,Sidransky E,de Silva R,Smith C,Spencer CCA,Stefansson H,Steinberg S,Stockton JD,Strange A,Su Z,Talbot K,Tanner CM,Tashakkori-Ghanbaria A,Tison F,Trabzuni D,Traynor BJ,Uitterlinden AG,Vandrovcova J,Velseboer D,Vidailhet M,Vukcevic D,Walker R,van de Warrenburg B,Weale ME,Wickremaratchi M,Williams N,Williams-Gray CH,Winder-Rhodes S,Stefansson K,Martinez M,Donnelly P,Singleton AB,Hardy J,Heutink P,Brice A,Gasser T,Wood NW,WTCCC2 (2011) A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease PLOS GENET, 7(6). 10.1371/journal.pgen.1002142.
  9. Nalls MA,Plagnol V,Hernandez DG,Sharma M,Sheerin UM,Saad M,Simon-Sanchez J,Schulte C,Lesage S,Sveinbjornsdottir S,Arepalli S,Barker R,Ben-Shlomo Y,Berendse HW,Berg D,Bhatia K,de Bie RMA,Biffi A,Bloem B,Bochdanovits Z,Bonin M,Bras JM,Brockmann K,Brooks J,Burn DJ,Charlesworth G,Chen HL,Chinnery PF,Chong S,Clarke CE,Cookson MR,Cooper JM,Corvol JC,Counsell C,Damier P,Dartigues JF,Deloukas P,Deuschl G,Dexter DT,van Dijk KD,Dillman A,Durif F,Durr A,Edkins S,Evans JR,Foltynie T,Gao JJ,Gardner M,Gibbs JR,Goate A,Gray E,Guerreiro R,Gustafsson O,Harris C,van Hilten JJ,Hofman A,Hollenbeck A,Holton J,Hu M,Huang XM,Huber H,Hudson G,Hunt SE,Huttenlocher J,Illig T,Jonsson PV,Lambert JC,Langford C,Lees A,Lichtner P,Limousin P,Lopez G,Lorenz D,McNeill A,Moorby C,Moore M,Morris HR,Morrison KE,Mudanohwo E,O'Sullivan SS,Pearson J,Perlmutter JS,Petursson H,Pollak P,Post B,Potter S,Ravina B,Revesz T,Riess O,Rivadeneira F,Rizzu P,Ryten M,Sawcer S,Schapira A,Scheffer H,Shaw K,Shoulson I,Sidransky E,Smith C,Spencer CCA,Stefansson H,Stockton JD,Strange A,Talbot K,Tanner CM,Tashakkori-Ghanbaria A,Tison F,Trabzuni D,Traynor BJ,Uitterlinden AG,Velseboer D,Vidailhet M,Walker R,van de Warrenburg B,Wickremaratchi M,Williams N,Williams-Gray CH,Winder-Rhodes S,Stefansson K,Martinez M,Hardy J,Heutink P,Brice A,Gasser T,Singleton AB,Wood NW,Int Parkinson Dis Genomics Consort ,Wellcome Trust Case-Control Consor (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies LANCET, 377(9766), 641 - 649. 10.1016/S0140-6736(10)62345-8.
  10. Charlesworth G,Soryal I,Smith S,Sisodiya SM (2009) Acute, localised paroxysmal pain as the initial manifestation of focal seizures: A case report and a brief review of the literature Pain, 141(3), 300 - 305. 10.1016/j.pain.2008.11.005.
  11. Docherty RJ,Charlesworth G,Farrag K,Bhattacharjee A,Costa S (2005) The use of the rat isolated vagus nerve for functional measurements of the effect of drugs in vitro. J Pharmacol Toxicol Methods, 51(3), 235 - 242. 10.1016/j.vascn.2004.08.011.

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