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Dr Gaetano Burriesci

  • Telephone:

    020 7679 3922

  • Extension:

    33922

  • Fax:

    020 73880180

  • Email:

    g.burriesci@ucl.ac.uk

  • Webpage:

    http://www.mecheng.ucl.ac.uk/staff/?staff_id=gb

  • Address:

    Department of Mechanical Engineering UCL Department of Mechanical Engineering,
    Torrington Place,
    London,
    WC1E 7JE

  • Appointments:

    Lecturer, Dept of Mechanical Engineering, Faculty of Engineering Science

Summary

Dr Gaetano Burriesci studied Mechanical Engineering at the University of Palermo (Italy), where he was awarded his MEng degree with first class honours (and a national prize for the best project in Experimental Mechanics) and gained his Doctorate in design and structural optimisation of artificial heart valves. He then was appointed Research Associate in the Department of Mechanical Engineering at the University of Sheffield, where he performed research activity in the field of biomechanics and collaborated with AorTech International Plc. in the development of an innovative synthetic leaflets heart valve. Subsequently, he joined SorinGroup SpA, which is an international company operating worldwide in the field of high-technology bioengineering for implantable medical devices, working as a Research Manager in the development and qualification of innovative cardiovascular devices. Gaetano joined the Department as a Lecturer in 2006.

Research Summary

Gaetano’s research activity of covers many disciplines, often combined, which include experimental and numerical stress analysis, non conventional materials and bioengineering. 

In recent years, driven by the escalating need for a more sustainable new generation healthcare, Gaetano has focused his activity in the definition of transformative healthcare treatments, by applying his research on novel material technologies, smart structures and advanced engineering approaches to the medical device area.  In collaboration with major biomedical industries, he has led the development of novel therapeutic technologies that are now widely adopted.

These include new families of semi-rigid annuloplasty rings for mitral repair based on super-elastic alloys and auxetic designs, that allow more physiological operative dynamics; new generation of sutureless artificial heart valves that allow significant reduction in cross-clamping time during surgery; new valve solutions based on the use of nano-composite polymers; collapsible prosthetic valves implantable without surgery and fully repositionable in case of misplacement (few of these implants are already on the market), and tissue in situ regeneration (with the UCL Centre of Gastroenterology and Nutrition).



This activity embraces basic and applied research on materials characterisation, fatigue behaviour, durability within hostile environments, physiological systems simulation, as well as the implementation of structural design optimisation procedures and the solution of new problems related with assessment.



The laboratories coordinated by Dr Burriesci are equipped with advanced facilities for the treatment and testing of biomaterials, and state-of-the-art testing devices for the assessment of the hydrodynamic and durability performances of cardiovascular prostheses.  




Research Activities

  • Application of liver cell biology to developing ne
  • Assessment of Cardiovascular Prostheses
  • Design of Artificial Heart Valves
  • Development of Genetically Modified Biological Heart Valves for Improved Durability
  • Development of Rapid Prototypes for Muscle Augmentation Using Magnetic Augmentation
  • Transcatheter Heart Valve

Recent Publications

Displaying 50 most recent publications. For the full list please visit UCL Discovery

  1. Tzamtzis S,Viquerat J,Yap J,Mullen MJ,Burriesci G (2013) Numerical analysis of the radial force produced by the Medtronic-CoreValve and Edwards-SAPIEN after transcatheter aortic valve implantation (TAVI) Medical Engineering and Physics, 35(1), 125 - 130.
  2. Tzamtzis S,Viquerat J,Yap J,Mullen MJ,Burriesci G (2012) Study of the radial force applied by transcatheter aortic valves on the left ventricular outflow tract, 2212.
  3. Burriesci G,Tzamtzis S,Seifalian AM (2012) Prosthesis delivery system.
  4. Rahmani B,Ghanbari H,Seifalian AM,Tzamtzis S,Burriesci G (2012) A new generation of aortic valve prosthesis: design, manufacture and hydrodynamic assessment., SBC2012-80609.
  5. Ducci A,Tzamtzis S,Mullen MJ,Burriesci G (2012) Phase-resolved velocity measurements in the Valsalva sinus downstream of a Transcatheter Aortic Valve..
  6. Rahmani B,Hossein G,Tzamtzis S,Burriesci G,Seifalian AM (2012) Polymeric heart valves.
  7. Sturla F,Conti C,Votta E,Della Corte A,Burriesci G,Faggian G,Redaelli A (2012) Physiological and BAV-affected aortic root dynamics: fluid-structure interaction simulation based on MRI-derived geometries., 1539.
  8. Lau K,Burriesci G,Diaz V (2012) Stress and strain based numerical simulation of mitral valve fibre remodelling, 1579.
  9. Rahmani B,Burriesci G,Mullen M,Seifalian A,Tzamtzis S,Yap J (2012) A New Generation Transcatheter Heart Valve with a Novel Nanocomposite Material and Fully Retrievable Design. JACC: Cardiovascular Interventions, 60(17), B34. 10.1016/j.jacc.2012.08.126.
  10. Lau KD,Diaz-Zuccarini V,Burriesci G (2012) Numerical Simulation of Fibre Remodelling in the Mitral Valve.
  11. Lau K,Burriesci G,Diaz-Zuccarini V (2012) Fluid-structure interaction simulation of the edge-to-edge repair of the mitral valve in functional and degenerative states., SBC2012-80288.
  12. Tzamtzis S,Mullen MJ,Yap J,Seifalian AM,Burriesci G (2012) Μια νεας γενιας αορτικη βαλβιδα διαδερμικης εμφυτευσης.
  13. Ducci A,Tzamtzis S,Mullen MJ,Burriesci G (2012) Assessment of Flow Dynamics Before and After Implantation of Transcatheter Aortic Valves.
  14. Tzamtzis S,Mullen MJ,Yap J,Burriesci G (2012) Comparative Hydrodynamic In-Vitro Assessment of the Edwards SAPIEN and Medtronic CoreValve Transcatheter Aortic Valves.
  15. Seifalian AM,Zervides C,Burriesci G (2012) HEART VALVE PROSTHESIS.
  16. Seifalian AM,Zervides C,Burriesci G (2012) Heart Valve Prosthesis.
  17. Bergamasco G,Burriesci G,Stacchino C (2012) Annuloplasty prosthesis.
  18. Stacchino C,Bergamasco G,Burriesci G,Righini G (2012) CARDIAC VALVE PROSTHESIS.
  19. Rahmani B,Tzamtzis S,Ghanbari H,Burriesci G,Seifalian AM (2012) Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer. J Biomech, 45, 1205 - 1211. 10.1016/j.jbiomech.2012.01.046.
  20. Rahmani, B ,Tzamtzis S,Ghanbari H,Burriesci G,Seifalian AM (2012) A novel aortic valve prosthesis made of a new nanocomposite polymer: hydrodynamic assessment. Cardiology, 121(2), 132 - 133.
  21. Bergamasco G,Burriesci G,Righini G,Stacchino C (2011) Cardiac-valve prosthesis.
  22. Righini G,Bergamasco G,Burriesci G (2011) EXPANDABLE PROSTHETIC VALVE CRIMPING DEVICE.
  23. Tzamtzis S,Yap J,Mullen M,Burriesci G (2011) A Direct In Vitro Comparison of the Edwards SAPIEN and Medtronic CoreValve Transcatheter Aortic Valve implantation (TAVI) Devices and a Surgical Counterpart.
  24. Lau KD,Burriesci G,Diaz-Zuccarini V (2011) Numerical simulation of mitral valve remodelling, 49.
  25. Burriesci G,Tzamtzis S,Viquerat J,Yap J,Mullen MJ (2011) Analisi numerica delle forze radiali prodotte dalle valvole artificiali endovascolari sul tratto di efflusso ventricolare, 143.
  26. Burriesci G,Tzamtzis S,Seifalian AM,Yap J,Mullen M (2011) A new generation fully retrievable transcatheter valve.
  27. Burriesci G,Tzamtzis S,Yap J,Mullen M (2011) Radial force of self-expanding and balloon expandable TAVI devices: A numerical simulation.
  28. Bergamasco G,Burriesci G,Stacchino C (2011) Annuloplasty prosthesis.
  29. Lau KD,Díaz-Zuccarini V,Scambler P,Burriesci G (2011) Fluid-structure interaction study of the edge-to-edge repair technique on the mitral valve Journal of Biomechanics, 44(13), 2409 - 2417.
  30. Tzamtzis S,Mullen M,Yap J,Burriesci G (2011) The effect of annulus ellipticity on the hydrodynamic performance of a Medtronic-CoreValve transcatheter aortic valve.
  31. Righini G,Bergamasco G,Burriesci G (2011) Expandable prosthetic valve crimping device, 1 - 12.
  32. Burriesci G (2011) Percutaneous Heart Valves (Invited Talk).
  33. Rahmani B,Ghanbari H,Tzamtzis S,Kabir AMN,Burriesci G,Seifalian AM (2011) Hydrodynamic Performance of a New Low Profile Semi-Stented Polymeric Heart Valve.
  34. Lau K,Diaz-Zuccarini V,Scambler P,Burriesci G (2010) Mitral Valve dynamics in structural and fluid-structure interaction models. Medical Engineering and Physics, 32(9-2), 1057 - 1064.
  35. Burriesci G,Cavallo Marincola F,Zervides C (2010) Design of a novel polymeric heart valve Journal of Medical Engineering & Technology, 34(1), 7 - 22. 10.3109/03091900903261241.
  36. Ghanbari H,Marashi M,Bakhshi R,Burriesci G,Seifalian AM (2010) Self-endothelialisation potential of a novel nanocomposite material for development of cardiovascular implant: the role of progenitor stem cells. Society of Academic & Research Surgery - Yearbook 2010, 51 - 52.
  37. Tzamtzis S,Ghanbari H,Seifalian A,Burriesci G (2010) A new generation aortic valve device for transcatheter implantation. Cardiology, 115(4), 292. 10.1159/000308357.
  38. Ghanbari H,Kidane AG,Burriesci G,Ramesh B,Darbyshire A,Seifalian AM (2010) The anti-calcification potential of a silsesquioxane nanocomposite polymer under in vitro conditions: potential material for synthetic leaflet heart valve. Acta Biomater, 6(11), 4249 - 4260. 10.1016/j.actbio.2010.06.015.
  39. Burriesci G (2010) Transcatheter Aortic Valve Implantation (Invited Talk).
  40. Burriesci G (2010) Engineering and design specifications of replacement aortic valves for transcatheter implantation (Invited Talk).
  41. Righini G,Bergamasco G,Burriesci G (2010) Expandable prosthetic valve crimping device.
  42. Ghanbari H,Rahmani B,Tzamtzis S,Burriesci G,Seifalian AM (2010) The regenerative capacity of endothelial progenitor cells in cardiovascular system: potential of in-situ endothelialisation of cardiovascular implants..
  43. Lau K,Diaz-Zuccarini V,Burriesci G,Scambler P (2010) Influence of Chordae Tendineae on Mitral Valve Dynamics: A Fluid-Structure Interaction Study.
  44. Ghanbari H,Darbyshire A,Ramesh B,Burriesci G,Seifalian AM (2010) A novel nanocomposite material for synthetic leaflet heart valve promotes proliferation and differentiation of circulating endothelial progenitor cells: toward in vivo tissue engineering heart valve.
  45. Burriesci G,Zervides C,Seifalian AM (2010) Heart valve prosthesis.
  46. Bergamasco G,Burriesci G,Stacchino C (2009) Cardiac-valve prosthesis.
  47. Righini G,Bergamasco G,Burriesci G (2009) EXPANDABLE PROSTHETIC VALVE CRIMPING DEVICE.
  48. Burriesci G,Bergamasco G (2009) Annuloplasty prosthesis with an auxetic structure.
  49. Ghanbari H,Viatge H,Kidane AG,Burriesci G,Tavakoli M,Seifalian AM (2009) Polymeric heart valves: New emerging hopes. Trends in Biotechnology, 27(6), 329 - 384. 10.1016/j.tibtech.2009.03.002.
  50. Kidane AG,Burriesci G,Edirisinghe M,Ghanbari H,Bonhoeffer P,Seifalian AM (2009) A novel nanocomposite polymer for development of synthetic heart valve leaflets. Acta Biomaterialia, 5(7), 2409 - 2417. 10.1016/j.actbio.2009.02.025.

Biography

Dr Gaetano Burriesci studied Mechanical Engineering at the University of Palermo (Italy), where he was awarded his MEng degree with first class honours (and a national prize for the best project in Experimental Mechanics) and gained his Doctorate in design and structural optimisation of artificial heart valves. He then was appointed Research Associate in the Department of Mechanical Engineering at the University of Sheffield, where he performed research activity in the field of biomechanics and collaborated with AorTech International Plc. in the development of an innovative synthetic leaflets heart valve. Subsequently, he joined SorinGroup SpA, which is an international company operating worldwide in the field of high-technology bioengineering for implantable medical devices, working as a Research Manager in the development and qualification of innovative cardiovascular devices. Gaetano joined the Department as a Lecturer in 2006.

Qualifications

  • 2000: Dottorato di Ricerca, Universita degli Studi di Palermo
  • 1996: Laurea, Universita degli Studi di Palermo
  • 1989: Diploma, To be updated