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Recent Publications

Most publications can be found on UCL Discovery: http://discovery.ucl.ac.uk/

 

This is a selection of 3 of our recent TB-related publications:

Mr Kartyk Moganeradj, Centre for Clinical Microbiology, UCL

Title: Insertion site mapping for repeated elements in Mycobacterium tuberculosis.
Mr Moganeradj who works is the Department of Bioanalysis & Horizon Technologies at HPA Colindale is a part-time PhD student in the Centre for Clinical Microbiology. [Link to summary of research].
Authors:Moganeradj K, Abubakar I, McHugh TD, Sonnenberg P, Arnold C. Journal: Journal of Microbiological Methods 92 (2013) 192–196
Link to full article

Professor Alimuddin Zumla, Centre for Clinical Microbiology, UCL

Title: Current concepts: Tuberculosis

Professor Zumla, from the Centre for Clinical Microbiology, joined three otherinternationally renowned TB experts: Professor Mario Raviglione, Director of the STOP TB Partnership, Geneva, Professor C Fordham von Reyn from Dartmouth-Hitchcock Medical Centre, New Hampshire, USA, and Dr Richard Hafner, of the National Institutes of health, Bethesda, USA  to review the current state of the art on tuberculosis (TB) in the New England published on 21 February 2013.

Authors: Zumla, A, Raviglione, M, Hafner, R, von Reyn cF. Journal/Ref: N Engl J Med 2013;368:745-55. DOI: 10.1056/NEJMra1200894

Link to full article: PDF download

Professor Alimuddin Zumla, Dr Matthew Bates and Dr Justin O'Grady, Centre for Clinical Microbiology, UCL

Title: Trends in Childhood Tuberculosis in Zambia: A Situation Analysis.
Abstract: To ascertain childhood tuberculosis (TB) trends, human immunodeficiency virus (HIV) co-infection rates and multi-drug resistant TB (MDR-TB) prevalence rates in Zambia.Methods: A retrospective review of Zambian annual TB notification data and National TB Programme reports for a 7 year period (2004-2011). TB trends were stratified by age and HIV status.Results: The total number of children notified during this period with all forms of TB was 40 976. A total of 2670 of 40 976 (6%) were smear-positive cases. Notification rates of all forms of childhood TB show a decline in trends from 135 per 100 000 population in 2004, to 69 per 100 000 population in 2011.Conclusions: Childhood TB is an important but neglected problem in Zambia highlighted by the fact that no data exists on HIV co-infection and MDR-TB. Strengthening of the National TB Programme and diagnostics services/algorithms are required to accurately define the TB burden, HIV co-infection and MDR-TB rates in children in Zambia.
Authors: Kapata N, Chanda-Kapata P, O'Grady J, Bates M, Mwaba P, Janssen S, Marais B, Cobelens F, Grobusch M, Zumla A.
Journal/Ref: J Trop Pediatr. 2013 Feb 13. PMID: 23243079 


Date: 26 February, 2013



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