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Prof Sir Ali Zumla leads series for WTBD18

23 March 2018

For World TB Day 2018, as part of our CCM UCL annual TB educational/CPD/advocacy contributions, Professor Sir Ali Zumla has led and coordinated three 'state of the art' reviews and five editorial comments in The Lancet journals, Nature Reviews Drugs Discovery and International Journal of Infectious Diseases.   

The Lancet Infectious Diseases TB Series has two substantive reviews co-authored by Professors Tim McHugh and Sir Zumla:
1) The first looks at the developmental pipeline and landscape of new and repurposed tuberculosis drugs, treatment regimens, and host-directed therapies for drug-sensitive and drug-resistant tuberculosis.
2) The second review details key developments and achievements in the search for new tuberculosis diagnostics and biomarkers

A Comment by Sir Zumla and Houses of Parliament colleagues from the All Party Parliamentary group on Global TB highlights the importance of the United National High Level Meeting on TB in September 2018 in New York. 

In The Lancet Respiratory Medicine TB series, a state of the art overview details progress in Global TB care, prevention, and research in year 3 of the End TB era.  The first comment published with colleagues at the WHO Global TB Department focuses on the need for more investments into TB research. The second Comment highlights the continuing conundrum of the role of T and B lymphocytes in immunity to TB and vaccine development.

In Nature Reviews Drugs Discovery, a Comment by Sir Zumla and colleagues  highlight progress in the development of therapeutic strategies for drug-resistant tuberculosis.

In the International Journal of Infectious Diseases an editorial comment with authors from Europe and Africa highlights the importance of taking forward the Stop TB Partnership and World Health Organization Joint Theme for World TB Day March 24th 2018 - "Wanted: Leaders for a TB-Free World. You can make history. End TB"

Downloads are also available via the links below:

Comment 1: Concrete action now: UN High-Level Meeting on Tuberculosis (Herbert et al)

Comment 2: Tuberculosis research and development: seeding the future (Lienhardt et al)

Comment 3: B cells or T cells in TB: a continuing conundrum

Comment 4: Taking forward the Stop TB Partnership and World Health Organization Joint Theme for World TB Day March 24th 2018 - "Wanted: Leaders for a TB-Free World. You can make history. End TB"

Comment 5: Accelerating the development of therapeutic strategies for drug-resistant tuberculosis

Review 1: Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies

Review 2: Tuberculosis: advances and challenges in development of new diagnostics and biomarkers

Review 3: The global tuberculosis epidemic and progress in care, prevention, and research: an overview in year 3 of the End TB era