Cardiovascular Systems

Complex diseases and disorders, such as cardiovascular disease, are logical targets for a systems biology approach in order to understand the structure and function of the cardiovascular system and the mechanisms involved in the disease pathogenesis. Systems biology can, for example, generate a quantitative and predictive interpretation of biological networks and signalling pathways, and provide models of physical function and phenotype.

The interests of the cardiovascular systems group include clinical electrophysiology, multi-scale computer modelling and imaging of the heart, genome wide association studies, and statistical analysis of genetic interactions.


Dr Pier Lambiase was awarded an MRC Systems Medicine grant for "An interactive in vivo and molecular investigation of the arrhythmogenic mechanisms of sudden cardiac death". Please see the news section for more details.


The first meeting of the cardiovascular systems group was held on 8th November. Speakers and topics included: Pier Lambiase (Basic and clinical electrophysiology), Tim Mohun (Imaging heart formation), Steve Humphries (Genome wide association studies, statistical analysis and genetic interactions) and Alexander Seifalian (Development of cardiovascular implants).


Page last modified on 17 nov 10 13:01

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