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The Department of Science and Technology Studies, UCL is an interdisciplinary centre for the integrated study of science's history, philosophy, sociology, communication and policy, located in the heart of London. Founded in 1921. Award winning for teaching and research, plus for our public engagement programme. Rated as outstanding by students at every level.
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Thinking About Science Episode 5
22 November 2012
Biological Complexity and Structural Biology
Interviewed by Dr Emma Tobin, STS UCL Interview Date Monday 19th November 2012
In this episode, Emma Tobin talks to Prof. Stephen Curry (Imperial) about biological complexity in Structural Biology. The relationship between theory and experimentation in the context of protein crystallography is discussed. Stephen explains why "whatever works is what you do" and why protein crystallography requires a degree of pragmatism. Despite this, he maintains that protein structure is well supported by the data and justified by the statistical analysis. It turns out that the mathematical methods that Fourier used in the 18th Century to show how heat travels down a metal rod are now being used to reveal the structure of proteins using X-Ray Crystallography! The use of databases to interrogate the Protein Data Bank is also explained and Stephen suggest that even these databases should be open access!
Prof. Stephen Curry (Imperial)
Interviewed by Dr Emma Tobin UCL STS
Recorded at Science and Technology Studies, UCL by Jo Pearson
Interview Date: 19th November 2012
Music: Andantino in A flat by JN Hummel, recorded by Jo Pearson
Page last modified on 22 nov 12 14:25 by Jo E Pearson
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