Epigenetics Working Group

The purpose of the Epigenetics Working Group is to foster the development of scientific collaborations, knowledge transfer and capacity building activities in these areas:

  • The HEROIC project provides a resource for functional studies into chromatin remodeling, mouse embryonic stem (ES) cell differentiation and regulation of the (epi)genome in general.
  • The aim of the iPSC Methylome project is to assess the efficiency of different reprogramming protocols using whole-genome DNA methylation (methylome) analysis.
  • Using methylome analysis, the Glioma Cancer Stem Cell Methylome project aims to identify and characterize epigenetic changes that occur during the differentiation of glioma CSC to committed progenitor cells.
  • The Human Epigenome Project provides an epigenetic resource of chromosomal DNA methylation reference profiles in human tissues and cell lines.
  • The focus of the Cancer methylome project is to provide a better understanding of how aberrant methylation affects the aetiology of cancer, and how we can use this information to identify novel diagnostic and prognostic markers or new therapeutic targets.
  • The High-throughput DNA methylation pipeline aims to increase the throughput of the assay as part of an integrated analysis pipeline to ultimately aid the discovery of novel biomarkers for use in disease diagnostics and drug development.

If you are interested in learning more about any of these initiatives, please contact Prof. Stephan Beck

Previous Meetings

  • Special Lecture held on Monday 12 September 2011 at 5 pm
    Invited Speaker: Professor Timothy Bestor, Dept of Genetics and Development, Columbia University Medical Center, New York, USA
    Title: "Biological functions of genomic methylation patterns"
  • First meeting held on Friday 28 January 2011 from 9:30 to 12 hrs
    Venue: Room 117, first floor, Anatomy building, Gower Street.

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