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Theme Overview
This theme has a research programme that encompasses the development, evaluation, and application of statistical and data science methods to address questions in health research. The overarching aim is to identify and apply the best possible statistical methods in health research, enabling the translation of reliable research findings to health care.
Much of the work within this theme is interdisciplinary and collaborative. There are established links with clinical and health research groups within UCL and beyond. In particular several staff members have joint posts with the UCLH/UCL Biomedical Research Centre (BRC) and the UCL Primary Care and Mental Health Clinical Trials Unit. There are strong collaborative links with the UCL Department of Applied Health Research, UCL Division of Psychiatry, LSE and Imperial College (Epidemiology and Biostatistics).
Current methodological research topics include risk prediction models, modelling clustered data, multistate models, model selection, survival models, trials methodology, methods for handling missing data, causal inference, regression discontinuity design, analysis of health economic data, multi-omics data integration, statistical / probabilistic genomics; mathematical biology; network models in genomics, and Bayesian Statistics.
This theme includes the Biostatistics Group and the Statistics for Health Economic Evaluation Group. Researchers from the Statistics for Health Economic Evaluation Group are founding and key members of two international consortia (ConVOI) and R-HTA, working on the development and dissemination of methods for the analysis of the value of information and for the establishment of statistical methods and software in health technology assessment.
Theme members
| Theme Members | |
|---|---|
Rumana Omar (Theme lead) | |
| Mariam Adeleke | |
| Gareth Ambler | |
| Javier Rubio Alvarez | |
| Gianluca Baio | |
| Julie Barber | |
| Tom Bartlett | |
| Karla Diaz Ordaz | |
| Nathan Green | |
| Takoua Jendoubi | |
| Baptiste Leurent | |
| Menelaos Pavlou | |
| Giampiero Marra | |
| Ardo Van Den Hout |
Selected recently funded research projects:
- Cancer Intervention and Surveillance Modelling Network (CISNET) Modeling Precision Interventions for Prostate Cancer Control. NIH (£970,000).
- MRC skills development Fellowship awarded to fund three years’ independent work developing novel statistical methodology for biomedical science applications. (£340 304).
- Mixed Semi-Continuous Copula Additive Regression Models with Applications in Insurance and Health Care. EPSRC (440,000).
- Royal Society Wellcome Trust Sir Henry Dale fellowship.
Research projects selected as REF 2021 case studies
- Research to develop a risk model to predict the chances of sudden cardiac death in people with hypertrophic cardiomyopathy
- Research to develop effective interventions for family carers of people with dementia
- Work to transform treatment for glaucoma patients reducing healthcare costs
- Research to improve care for people going through a mental health crisis
Biostatistics Group research grants
Statistics for Health Economic Evaluation Group research grants