Structural Biology and Molecular Biophysics
Mechanisms of eukaryotic transcription via multidisciplinary structural, biochemical and biophysical approaches.
Studies of protein dynamics by advanced NMR techniques with applications to human histone deacetylases and the von Willebrand Factor
Electron Paramagnetic Resonance (EPR) spectroscopy: Applications in structural biology and materials science
Reaction mechanism of enzyme catalysis with emphasis on mitochondrial electron transfer chains and protonmotive cytochrome c oxidase; FTIR spectroscopy.
Research: Molecular interactions in complement, coagulation and antibodies using multidisciplinary biophysical and modelling strategies
Vibrational infrared spectroscopy: basic studies of biological electron and proton transfer and applied uses in medical diagnostics
Structural studies of proteins and protein complexes by means of mass spectrometry, ion mobility mass spectrometry and proteomics approaches.
research focuses on the structural biology of Hsp90, in particular its role in assembly of the kinetochore and the importance of post-translational modifcation of its cochaperones for Hsp90 function.
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