Prof Aroon Hingorani

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Personal Profile

Name: Aroon Hingorani Email: a.hingorani@ucl.ac.uk
Title: Prof Tel: 020 3108 3080
Department: Institute of Cardiovascular Science Fax: 020 7813 0242
Position: Chair of Genetic Epidemiology (Honorary Consultant) Address: 1-19 Torrington Place, , London, WC1E 6BT
Research Domain: Basic Life Sciences, Cardiometabolic Science, Neuroscience, Personalised Medicine, Populations & Lifelong Health Web Page:  

Profile

Research Description

The Genetic Epidemiology Group, led by Professor Aroon Hingorani (British Heart Foundation Senior Research Fellow), investigates the implications (and applications) of new genetic advances for personal and public health. The work is interdisciplinary, integrative and collaborative. The Institute of Epidemiology and Health Care hosts several large, highly phenotyped population-based cohort studies that provide an excellent resource for genetic epidemiology. The group plays a central role in large-scale collaborative studies both nationally and internationally. There are close collaborations with groups engaged in health outcomes research and research using national disease registries. The aims of the group are thus closely aligned to those of the Institute as a whole, which are to enhance the health of patients and populations by promoting public health and improving clinical care. The skills mix of epidemiological, clinical, statistical and behavioural science in the Institute provides the scientific basis to underpin our internationally competitive programme.

There have been a range of strategic developments at UCL that facilitate the work of the group. Support for genotyping and bioinformatics exists through UCL and Partners centralized platform technology service (http://www.ucl.ac.uk/researchdeanery/platform_technologies/) and UCL Genomics (http://www.genomics.ucl.ac.uk/). The Genetic Epidemiology Research Group is also affiliated to the newly created UCL Genetics Institute (http://www.ucl.ac.uk/ugi/), which offers centralized core support for bioinformatics, and statistical genetics as well as providing a framework for interfaculty research in human genetics across UCL. Members and affiliates of UGI include clinicians, geneticists, epidemiologists and statisticians. Much of the work of the Genetic Epidemiology Research group is in the field of cardiovascular disease and there are also established and expanding links with the basic sciences and clinical research in cardiovascular disease through the Division of Medicine and the UCL Institute of Cardiovascular Sciences (http://www.ucl.ac.uk/cardiovascular/). Finally, there are established and highly productive links with several groups in the Non-Communicable Disease Epidemiology Unit at London School of Hygiene and Tropical Medicine, including links with statistical genetics.

Current areas of activity include:

* Using genetic approaches to understand causal pathways in the onset and progression of common complex disease;

* Exploring the potential for large scale genetic studies in highly phenotyped populations to model the effects of new drug therapies;

* Co-ordination of collaborative genetic work involving the population studies hosted by the Division to exploit opportunities for pooled cross-cohort analyses for the understanding of the factors governing the development of chronic diseases;

* Contributing to the development and application of appropriate methods for the design, conduct and analysis of large scale population studies incorporating genomic information, and the implementation of the findings for risk prediction and causal inference.


Research Activities

A life course approach to the study of adult physical capability

A wide range of cardiovascular diseases

Cardiovascular disease

Critical Care Medicine

Epidemiology and public health

Genetic epidemiology of cardiovascular disease

Interface between physical health and mental health

Education Description

UCL Collaborators

Prof John Deanfield; Dr Leah Li; Dr Mike Grocott; Dr Geoffrey Bellingan; Dr Anne Peasey; Dr Mark Peters; Dr Irene Petersen; Prof Christine Power; Prof Mika Kivimaki; Prof Michael Marmot; Prof Rumana Omar; Prof Marcus Richards; Prof Hugh Montgomery; Prof John Martin; Prof Mervyn Singer; Dr Bernardine Stegeman; Miss Janice Tsui; Prof Diana Kuh; Prof Monty Mythen; Dr Kate Walters; Prof Irwin Nazareth; Dr Greta Rait; Prof Harry Hemingway; Dr David Osborn; Prof Steve Humphries; Dr Ben Hanson; Dr Olga Vikhireva; Dr Ann Walker

External Collaborators

Publications

    2014

    • Holmes MV, Lange LA, Palmer T, Lanktree MB, North KE, Almoguera B, Buxbaum S, Chandrupatla HR, Elbers CC, Guo Y, Hoogeveen RC, Li J, Li YR, Swerdlow DI, Cushman M, Price TS, Curtis SP, Fornage M, Hakonarson H, Patel SR, Redline S, Siscovick DS, Tsai MY, Wilson JG, van der Schouw YT, Fitzgerald GA, Hingorani AD, Casas JP, de Bakker PI, Rich SS, Schadt EE, Asselbergs FW, Reiner AP, Keating BJ (2014). Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis.. Am J Hum Genet, , - . doi:10.1016/j.ajhg.2013.12.014
    • Holmes MV, Exeter HJ, Folkersen L, Nelson CP, Guardiola M, Cooper JA, Sofat R, Boekholdt SM, Khaw KT, Li KW, Smith AJ, Van't Hooft F, Eriksson P, Franco-Cereceda A, Asselbergs FW, Boer JM, Onland-Moret NC, Hofker M, Erdmann J, Kivimaki M, Kumari M, Reiner AP, Keating BJ, Humphries SE, Hingorani AD, Mallat Z, Samani NJ, Talmud PJ (2014). A Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA2)-V Isoenzyme in Coronary Heart Disease: A Modified Mendelian Randomization Analysis Using PLA2G5 Expression Levels.. Circ Cardiovasc Genet, , - . doi:10.1161/CIRCGENETICS.113.000271
    • Holmes MV, Asselbergs FW, Palmer TM, Drenos F, Lanktree MB, Nelson CP, Dale CE, Padmanabhan S, Finan C, Swerdlow DI, Tragante V, van Iperen EP, Sivapalaratnam S, Shah S, Elbers CC, Shah T, Engmann J, Giambartolomei C, White J, Zabaneh D, Sofat R, McLachlan S, on behalf of the UCLEB consortium , Doevendans PA, Balmforth AJ, Hall AS, North KE, Almoguera B, Hoogeveen RC, Cushman M, Fornage M, Patel SR, Redline S, Siscovick DS, Tsai MY, Karczewski KJ, Hofker MH, Verschuren WM, Bots ML, van der Schouw YT, Melander O, Dominiczak AF, Morris R, Ben-Shlomo Y, Price J, Kumari M, Baumert J, Peters A, Thorand B, Koenig W, Gaunt TR, Humphries SE, Clarke R, Watkins H, Farrall M, Wilson JG, Rich SS, de Bakker PI, Lange LA, Davey Smith G, Reiner AP, Talmud PJ, Kivimäki M, Lawlor DA, Dudbridge F, Samani NJ, Keating BJ, Hingorani AD, Casas JP (2014). Mendelian randomization of blood lipids for coronary heart disease.. Eur Heart J, , - . doi:10.1093/eurheartj/eht571

    2013

    • Harrison SC, Smith AJ, Jones GT, Swerdlow DI, Rampuri R, Bown MJ, Aneurysm Consortium , Folkersen L, Baas AF, de Borst GJ, Blankensteijn JD, Price JF, van der Graaf Y, McLachlan S, Agu O, Hofman A, Uitterlinden AG, Franco-Cereceda A, Ruigrok YM, van't Hof FN, Powell JT, van Rij AM, Casas JP, Eriksson P, Holmes MV, Asselbergs FW, Hingorani AD, Humphries SE (2013). Interleukin-6 receptor pathways in abdominal aortic aneurysm.. Eur Heart J, 34(48), 3707 - 3716. doi:10.1093/eurheartj/ehs354
    • Hu Y, Li L, Ehm MG, Bing N, Song K, Nelson MR, Talmud PJ, Hingorani AD, Kumari M, Kivimäki M, Xu CF, Waterworth DM, Whittaker JC, Abecasis GR, Spino C, Kang HM (2013). The benefits of using genetic information to design prevention trials.. Am J Hum Genet, 92(4), 547 - 557. doi:10.1016/j.ajhg.2013.03.003
    • Chakravarthy U, McKay GJ, de Jong PT, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Vioque J, Young IS, Sofat R, Hingorani AD, Fletcher AE (2013). ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.. Ophthalmology, 120(2), 342 - 348. doi:10.1016/j.ophtha.2012.08.004
    • Khan TA, Shah T, Prieto D, Zhang W, Price J, Fowkes GR, Cooper J, Talmud PJ, Humphries SE, Sundstrom J, Hubacek JA, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Abdollahi MR, Slooter AJ, Szolnoki Z, Sandhu M, Wareham N, Frikke-Schmidt R, Tybjærg-Hansen A, Fillenbaum G, Heijmans BT, Katsuya T, Gromadzka G, Singleton A, Ferrucci L, Hardy J, Worrall B, Rich SS, Matarin M, Whittaker J, Gaunt TR, Whincup P, Morris R, Deanfield J, Donald A, Davey Smith G, Kivimaki M, Kumari M, Smeeth L, Khaw KT, Nalls M, Meschia J, Sun K, Hui R, Day I, Hingorani AD, Casas JP (2013). Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.. Int J Epidemiol, 42(2), 475 - 492. doi:10.1093/ije/dyt034
    • Bodalia PN, Grosso AM, Sofat R, Macallister RJ, Smeeth L, Dhillon S, Casas JP, Wonderling D, Hingorani AD (2013). Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials.. Br J Clin Pharmacol, 76(5), 649 - 667. doi:10.1111/bcp.12083
    • Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL, Genetic Investigation of Anthropometric Traits-GIANT Consortium , Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E (2013). Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.. PLoS Med, 10(2), e1001383 - . doi:10.1371/journal.pmed.1001383
    • Hingorani AD, Windt DA, Riley RD, Abrams K, Moons KG, Steyerberg EW, Schroter S, Sauerbrei W, Altman DG, Hemingway H, PROGRESS Group (2013). Prognosis research strategy (PROGRESS) 4: stratified medicine research.. BMJ, 346, e5793 - .
    • Giambartolomei C, Vukcevic D, Schadt EE, Hingorani AD, Wallace C, Plagnol V (2013). Bayesian test for co-localisation between pairs of genetic association studies using summary statistics. , , - .
    • Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EP, Li M, Leusink M, Trompet S, Verschuren JJ, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, Hooft FV, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Leach IM, Breitling LP, Brenner H, Dallmeier D, Franco-Cereceda A, Boer J, Stephens JW, Hofker MH, Tedgui A, Hofman A, Uitterlinden AG, Adamkova V, Pitha J, Onland-Moret NC, Cramer MJ, Nathoe HM, Spiering W, Klungel OH, Kumari M, Whincup PH, Morrow DA, Braund PS, Hall AS, Olsson AG, Doevendans PA, Trip MD, Tobin MD, Hamsten A, Watkins H, Koenig W, Nicolaides AN, Teupser D, Day IN, Carlquist JF, Gaunt TR, Ford I, Sattar N, Tsimikas S, Schwartz GG, Lawlor DA, Morris RW, Sandhu MS, Poledne R, Maitland-van der Zee AH, Khaw KT, Keating BJ, van der Harst P, Price JF, Mehta SR, Yusuf S, Witteman JC, Franco OH, Jukema JW, de Knijff P, Tybjaerg-Hansen A, Rader DJ, Farrall M, Samani J, Kivimaki M, Fox KA, Humphries SE, Anderson JL, Boekholdt SM, Palmer TM, Eriksson P, Paré G, Hingorani AD, Sabatine MS, Mallat Z, Casas JP, Talmud PJ (2013). Secretory Phospholipase A2-IIA and Cardiovascular Disease: a Mendelian randomization study.. J Am Coll Cardiol, , - . doi:10.1016/j.jacc.2013.06.044
    • Shah T, Engmann J, Finan C, Holmes MV, Kumari M, Kivimaki M, Casas JP, Hingorani AD, Dale C, Amuzu A, Warren H, Ebrahim S, Dudbridge F, Shah S, White J, Giambartolomei C, Zabaneh D, Plagnol V, McLachlan S, Price J, Cavadino A, Power C, Hypponen E, Wong A, Ong K, Richards M, Hardy R, Kuh D, Wareham N, Gaunt T, Davies T-L, Lawlor DA, Day IN, Drenos F, Cooper J, Talmud PJ, Humphries SE, Sofat R, Caulfield M, Ben-Shlomo Y, Whincup P, Morris R, Strachan MWJ, Whittaker JC (2013). Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS ONE, 8(8), - . doi:10.1371/journal.pone.0071345
    • den Hoed M, Luan J, Langenberg C, Cooper C, Sayer AA, Jameson K, Kumari M, Kivimaki M, Hingorani AD, Grøntved A, Khaw KT, Ekelund U, Wareham NJ, Loos RJ (2013). Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.. Int J Obes (Lond), 37(2), 191 - 196. doi:10.1038/ijo.2012.34
    • Shah S, Casas JP, Drenos F, Whittaker J, Deanfield J, Swerdlow DI, Holmes MV, Kivimaki M, Langenberg C, Wareham N, Gertow K, Sennblad B, Strawbridge RJ, Baldassarre D, Veglia F, Tremoli E, Gigante B, de Faire U, Kumari M, Talmud PJ, Hamsten A, Humphries SE, Hingorani AD (2013). Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.. Circ Cardiovasc Genet, 6(1), 63 - 72. doi:10.1161/CIRCGENETICS.112.963140
    • Shah S, Casas JP, Gaunt TR, Cooper J, Drenos F, Zabaneh D, Swerdlow DI, Shah T, Sofat R, Palmen J, Kumari M, Kivimaki M, Ebrahim S, Smith GD, Lawlor DA, Talmud PJ, Whittaker J, Day IN, Hingorani AD, Humphries SE (2013). Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.. Eur Heart J, 34(13), 972 - 981. doi:10.1093/eurheartj/ehs243
    • Sofat R, Mangione PP, Gallimore JR, Hakobyan S, Hughes TR, Shah T, Goodship T, D'Aiuto F, Langenberg C, Wareham N, Morgan BP, Pepys MB, Hingorani AD (2013). Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay.. J Immunol Methods, 390(1-2), 63 - 73. doi:10.1016/j.jim.2013.01.009
    • Talmud PJ, Shah S, Whittall R, Futema M, Howard P, Cooper JA, Harrison SC, Li K, Drenos F, Karpe F, Neil HA, Descamps OS, Langenberg C, Lench N, Kivimaki M, Whittaker J, Hingorani AD, Kumari M, Humphries SE (2013). Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.. Lancet, 381(9874), 1293 - 1301. doi:10.1016/S0140-6736(12)62127-8
    • Shah T, Zabaneh D, Gaunt T, Swerdlow DI, Shah S, Talmud PJ, Day IN, Whittaker J, Holmes MV, Sofat R, Humphries SE, Kivimaki M, Kumari M, Hingorani AD, Casas JP (2013). Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.. Circ Cardiovasc Genet, 6(2), 163 - 170. doi:10.1161/CIRCGENETICS.112.964254

    2012

    • Sofat R, Casas JP, Grosso AM, Prichard BNC, Smeeth L, MacAllister R, Hingorani AD (2012). Could NICE guidance on the choice of blood pressure lowering drugs be simplified?. BRITISH MEDICAL JOURNAL, 344, - . doi:10.1136/bmj.d8078
    • Asselbergs F, Guo Y, van Iperen EA, Sivapalaratnam S, Tragante V, Lanktree M, Lange L, Almoguera B, Appelman Y, Barnard J, Baumert J, Beitelshees A, Bhangale T, Chen Y-D, Gaunt T, Gong Y, Hopewell J, Johnson T, Kleber M, Langaee T, Li M, Li Y, Liu K, McDonough C, Meijs ML, Middelberg RS, Musunuru K, Nelson C, O'Connell J, Padmanabhan S, Pankow J, Pankratz N, Rafelt S, Rajagopalan R, Romaine SR, Schork N, Shaffer J, Shen H, Smith E, Tischfield S, van der Most P, van Vliet-Ostaptchouk J, Verweij N, Volcik K, Zhang L, Bailey K, Bailey K, Bauer F, Boer JA, Braund P, Burt A, Burton P, Buxbaum S, Chen W, Cooper-DeHoff R, Cupples L, deJong J, Delles C, Duggan D, Fornage M, Furlong C, Glazer N, Gums J, Hastie C, Holmes M, Illig T, Kirkland S, Kivimaki M, Klein R, Klein B, Kooperberg C, Kottke-Marchant K, Kumari M, LaCroix A, Mallela L, Murugesan G, Ordovas J, Ouwehand W, Post W, Saxena R, Scharnagl H, Schreiner P, Shah T, Shields D, Shimbo D, Srinivasan S, Stolk R, Swerdlow D, Taylor Jr H, Topol E, Toskala E, van Pelt J, van Setten J, Yusuf S, Whittaker J, Zwinderman AH, Anand S, Balmforth A, Berenson G, Bezzina C, Boehm B, Boerwinkle E, Casas J, Caulfield M, Clarke R, Connell J, Cruickshanks K, Davidson K, Day IM, de Bakker PW, Doevendans P, Dominiczak A, Hall A, Hartman C, Hengstenberg C, Hillege H, Hofker M, Humphries S, Jarvik G, Johnson J, Kaess B, Kathiresan S, Koenig W, Lawlor D, März W, Melander O, Mitchell B, Montgomery G, Munroe P, Murray S, Newhouse S, Onland-Moret N, Poulter N, Psaty B, Redline S, Rich S, Rotter J, Schunkert H, Sever P, Shuldiner A, Silverstein R, Stanton A, Thorand B, Trip M, Tsai M, van der Harst P, van der Schoot E, van der Schouw Y, Verschuren WM, Watkins H, Wilde AM, Wolffenbuttel BR, Whitfield J, Hovingh G, Ballantyne C, Wijmenga C, Reilly M, Martin N, Wilson J, Rader D, Samani N, Reiner A, Hegele R, Kastelein JP, Hingorani A, Talmud P, Hakonarson H, Elbers C, Keating B, Drenos F (2012). Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci. American Journal of Human Genetics, , - .
    • Berry DJ, Vimaleswaran KS, Whittaker JC, Hingorani AD, Hyppönen E (2012). Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.. PLoS One, 7(5), e37465 - . doi:10.1371/journal.pone.0037465
    • Munafò MR, Timofeeva MN, Morris RW, Prieto-Merino D, Sattar N, Brennan P, Johnstone EC, Relton C, Johnson PC, Walther D, Whincup PH, Casas JP, Uhl GR, Vineis P, Padmanabhan S, Jefferis BJ, Amuzu A, Riboli E, Upton MN, Aveyard P, Ebrahim S, Hingorani AD, Watt G, Palmer TM, Timpson NJ, EPIC Study Group , Davey Smith G (2012). Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure.. J Natl Cancer Inst, 104(10), 740 - 748. doi:10.1093/jnci/djs191
    • Staines-Urias E, Paez MC, Doyle P, Dudbridge F, Serrano NC, Ioannidis JP, Keating BJ, Hingorani AD, Casas JP (2012). Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis.. Int J Epidemiol, 41(6), 1764 - 1775. doi:10.1093/ije/dys162
    • Sofat R, Casas JP, Webster AR, Bird AC, Mann SS, Yates JR, Moore AT, Sepp T, Cipriani V, Bunce C, Khan JC, Shahid H, Swaroop A, Abecasis G, Branham KE, Zareparsi S, Bergen AA, Klaver CC, Baas DC, Zhang K, Chen Y, Gibbs D, Weber BH, Keilhauer CN, Fritsche LG, Lotery A, Cree AJ, Griffiths HL, Bhattacharya SS, Chen LL, Jenkins SA, Peto T, Lathrop M, Leveillard T, Gorin MB, Weeks DE, Ortube MC, Ferrell RE, Jakobsdottir J, Conley YP, Rahu M, Seland JH, Soubrane G, Topouzis F, Vioque J, Tomazzoli L, Young I, Whittaker J, Chakravarthy U, de Jong PT, Smeeth L, Fletcher A, Hingorani AD (2012). Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype.. Int J Epidemiol, 41(1), 250 - 262. doi:10.1093/ije/dyr204
    • Sofat R, Casas JP, Grosso AM, Prichard BN, Smeeth L, MacAllister R, Hingorani AD (2012). Could NICE guidance on the choice of blood pressure lowering drugs be simplified?. BMJ, 344, d8078 - .
    • Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, DIAGRAM Consortium , MAGIC Investigators , Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga JJ, Song K, Goel A, Egan JM, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hicks AA, Hillman DR, Hingorani AD, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Oostra BA, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watk (2012). A genome-wide association search for type 2 diabetes genes in African Americans.. PLoS One, 7(1), e29202 - . doi:10.1371/journal.pone.0029202
    • Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM, Look AHEAD Research Group , DIAGRAM consortium , Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ (2012). Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.. Am J Hum Genet, 90(3), 410 - 425. doi:10.1016/j.ajhg.2011.12.022
    • Papp AC, Pinsonneault JK, Wang D, Newman LC, Gong Y, Johnson JA, Pepine CJ, Kumari M, Hingorani AD, Talmud PJ, Shah S, Humphries SE, Sadee W (2012). Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.. PLoS One, 7(3), e31930 - . doi:10.1371/journal.pone.0031930
    • Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium , Hingorani AD, Casas JP (2012). The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.. Lancet, 379(9822), 1214 - 1224. doi:10.1016/S0140-6736(12)60110-X
    • Jones A, Charakida M, Falaschetti E, Hingorani AD, Finer N, Masi S, Donald AE, Lawlor DA, Smith GD, Deanfield JE (2012). Adipose and height growth through childhood and blood pressure status in a large prospective cohort study.. Hypertension, 59(5), 919 - 925. doi:10.1161/HYPERTENSIONAHA.111.187716
    • Holmes MV, Hingorani AD, Casas JP (2012). CYP2C19 Genotype and Cardiovascular Events Reply. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 307(14), 1484 - 1485. doi:10.1001/jama.2012.446
    • Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, DIAGRAM+ Consortium , MAGIC Consortium , GLGC Investigators , MuTHER Consortium , Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki (2012). Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.. PLoS Genet, 8(3), e1002607 - . doi:10.1371/journal.pgen.1002607
    • Sutaria S, Philipson P, Fitzpatrick NK, Abrams K, Moreno SG, Timmis A, Hingorani AD, Hemingway H (2012). Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease.. Heart, 98(8), 615 - 622. doi:10.1136/heartjnl-2011-300862
    • Angelakopoulou A, Shah T, Sofat R, Shah S, Berry DJ, Cooper J, Palmen J, Tzoulaki I, Wong A, Jefferis BJ, Maniatis N, Drenos F, Gigante B, Hardy R, Laxton RC, Leander K, Motterle A, Simpson IA, Smeeth L, Thomson A, Verzilli C, Kuh D, Ireland H, Deanfield J, Caulfield M, Wallace C, Samani N, Munroe PB, Lathrop M, Fowkes FG, Marmot M, Whincup PH, Whittaker JC, de Faire U, Kivimaki M, Kumari M, Hypponen E, Power C, Humphries SE, Talmud PJ, Price J, Morris RW, Ye S, Casas JP, Hingorani AD (2012). Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.. Eur Heart J, 33(3), 393 - 407. doi:10.1093/eurheartj/ehr225
    • Yiannakouris N, Cooper JA, Shah S, Drenos F, Ireland HA, Stephens JW, Li KW, Elkeles R, Godsland IF, Kivimaki M, Hingorani AD, Kumari M, Talmud PJ, Humphries SE (2012). IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.. Nutr Metab Cardiovasc Dis, 22(12), 1024 - 1030. doi:10.1016/j.numecd.2011.05.009
    • Hingorani AD, Sofat R, Morris RW, Whincup P, Lowe GD, Mindell J, Sattar N, Casas JP, Shah T (2012). Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease?. Eur Heart J, 33(18), 2258 - 2264. doi:10.1093/eurheartj/ehs168
    • Costelloe SJ, El-Sayed Moustafa JS, Drenos F, Palmen J, Li Q, Whiting S, Thomas M, Kivimaki M, Kumari M, Hingorani AD, Tzoulaki I, Järvelin MR, Ruokonen A, Hartikainen AL, Pouta A, Walters RG, Blakemore AI, Humphries SE, Coin LJ, Talmud PJ (2012). Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.. Circ Cardiovasc Genet, 5(5), 555 - 560. doi:10.1161/CIRCGENETICS.111.961037
    • Douglas IJ, Evans SJ, Hingorani AD, Grosso AM, Timmis A, Hemingway H, Smeeth L (2012). Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.. BMJ, 345, e4388 - .
    • Gaunt TR, Shah S, Nelson CP, Drenos F, Braund PS, Adeniran I, Folkersen L, Lawlor DA, Casas JP, Amuzu A, Kivimaki M, Whittaker J, Eriksson P, Zhang H, Hancox JC, Tomaszewski M, Burton PR, Tobin MD, Humphries SE, Talmud PJ, Macfarlane PW, Hingorani AD, Samani NJ, Kumari M, Day IN (2012). Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.. Circ Cardiovasc Genet, 5(6), 630 - 638. doi:10.1161/CIRCGENETICS.112.962852
    • Denaxas SC, George J, Herrett E, Shah AD, Kalra D, Hingorani AD, Kivimaki M, Timmis AD, Smeeth L, Hemingway H (2012). Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER).. Int J Epidemiol, 41(6), 1625 - 1638. doi:10.1093/ije/dys188
    • Harrison SC, Zabaneh D, Asselbergs FW, Drenos F, Jones GT, Shah S, Gertow K, Sennblad B, Strawbridge RJ, Gigante B, Holewijn S, De Graaf J, Vermeulen S, Folkersen L, van Rij AM, Baldassarre D, Veglia F, Talmud PJ, Deanfield JE, Agu O, Kivimaki M, Kumari M, Bown MJ, Nyyssönen K, Rauramaa R, Smit AJ, Franco-Cereceda A, Giral P, Mannarino E, Silveira A, Syvänen A-C, de Borst GJ, van der Graaf Y, de Faire U, Baas AF, Blankensteijn JD, Wareham NJ, Fowkes G, Tzoulaki I, Price JF, Tremoli E, Hingorani AD, Eriksson P, Hamsten A, Humphries SE (2012). A gene-centric study of common carotid artery remodelling. Atherosclerosis, , - .
    • Smith AJP, Howard P, Palmen J, Talmud PJ, Humphries SE, Shah S, Giambartolomei C, Eriksson P, Folkersen L, Stender S, Tybjærg-Hansen A, Kumari M, Hingorani AD (2012). Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays. PLoS Genetics, 8(8), - . doi:10.1371/journal.pgen.1002908

    2011

    • International Consortium for Blood Pressure Genome-Wide Association Studies , Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, CARDIoGRAM consortium , CKDGen Consortium , KidneyGen Consortium , EchoGen consortium , CHARGE-HF consortium , Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stančáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Harti (2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.. Nature, 478(7367), 103 - 109. doi:10.1038/nature10405
    • Holmes MV, Newcombe P, Hubacek JA, Sofat R, Ricketts SL, Cooper J, Breteler MM, Bautista LE, Sharma P, Whittaker JC, Smeeth L, Fowkes FG, Algra A, Shmeleva V, Szolnoki Z, Roest M, Linnebank M, Zacho J, Nalls MA, Singleton AB, Ferrucci L, Hardy J, Worrall BB, Rich SS, Matarin M, Norman PE, Flicker L, Almeida OP, van Bockxmeer FM, Shimokata H, Khaw KT, Wareham NJ, Bobak M, Sterne JA, Smith GD, Talmud PJ, van Duijn C, Humphries SE, Price JF, Ebrahim S, Lawlor DA, Hankey GJ, Meschia JF, Sandhu MS, Hingorani AD, Casas JP (2011). Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.. Lancet, 378(9791), 584 - 594. doi:10.1016/S0140-6736(11)60872-6
    • Shah AD, Nicholas O, Timmis AD, Feder G, Abrams KR, Chen R, Hingorani AD, Hemingway H (2011). Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis.. PLoS Med, 8(5), e1000439 - . doi:10.1371/journal.pmed.1000439
    • Zabaneh D, Kumari M, Sandhu M, Wareham N, Wainwright N, Papamarkou T, Hopewell J, Clarke R, Li K, Palmen J, Talmud PJ, Kronenberg F, Lamina C, Summerer M, Paulweber B, Price J, Fowkes G, Stewart M, Drenos F, Shah S, Shah T, Casas JP, Kivimaki M, Whittaker J, Hingorani AD, Humphries SE (2011). Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.. Atherosclerosis, 217(2), 447 - 451. doi:10.1016/j.atherosclerosis.2011.04.015
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    • Shah S, Nelson CP, Gaunt TR, van der Harst P, Barnes T, Braund PS, Lawlor DA, Casas JP, Padmanabhan S, Drenos F, Kivimaki M, Talmud PJ, Humphries SE, Whittaker J, Morris RW, Whincup PH, Dominiczak A, Munroe PB, Johnson T, Goodall AH, Cambien F, Diemert P, Hengstenberg C, Ouwehand WH, Felix JF, Glazer NL, Tomaszewski M, Burton PR, Tobin MD, van Veldhuisen DJ, de Boer RA, Navis G, van Gilst WH, Mayosi BM, Thompson JR, Kumari M, MacFarlane PW, Day IN, Hingorani AD, Samani NJ (2011). Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.. Circ Cardiovasc Genet, 4(6), 626 - 635. doi:10.1161/CIRCGENETICS.111.960203
    • Zabaneh D, Gaunt TR, Kumari M, Drenos F, Shah S, Berry D, Power C, Hypponen E, Shah T, Palmen J, Pallas J, Talmud PJ, Casas JP, Sofat R, Lowe G, Rumley A, Morris RW, Whincup PH, Rodriguez S, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Kivimaki M, Whittaker J, Hingorani AD, Day IN, Humphries SE (2011). Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.. Ann Hum Genet, 75(4), 456 - 467. doi:10.1111/j.1469-1809.2011.00654.x
    • Minassian C, D'Aiuto F, Hingorani AD (2011). Invasive Dental Treatment and Risk for Vascular Events RESPONSE. ANN INTERN MED, 154(6), 442 - 442. doi:10.1059/0003-4819-154-6-201103150-00016
    • Jensen AC, Barker A, Kumari M, Brunner EJ, Kivimäki M, Hingorani AD, Wareham NJ, Tabák AG, Witte DR, Langenberg C (2011). Associations of common genetic variants with age-related changes in fasting and postload glucose: evidence from 18 years of follow-up of the Whitehall II cohort.. Diabetes, 60(5), 1617 - 1623. doi:10.2337/db10-1393
    • Talmud PJ, Cooper JA, Gaunt T, Holmes MV, Shah S, Palmen J, Drenos F, Shah T, Kumari M, Kivimaki M, Whittaker J, Lawlor DA, Day IN, Hingorani AD, Casas JP, Humphries SE (2011). Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies.. Diabetologia, 54(7), 1710 - 1719. doi:10.1007/s00125-011-2108-6
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    • Holmes MV, Harrison S, Talmud PJ, Hingorani AD, Humphries SE (2011). Utility of genetic determinants of lipids and cardiovascular events in assessing risk.. Nat Rev Cardiol, 8(4), 207 - 221. doi:10.1038/nrcardio.2011.6
    • Grosso AM, Bodalia PN, Macallister RJ, Hingorani AD, Moon JC, Scott MA (2011). Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis.. Int J Clin Pract, 65(3), 253 - 263. doi:10.1111/j.1742-1241.2011.02633.x
    • Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer AD, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszewski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn GW, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ, Hugh Watkins on behalf of PROCARDIS , Grant SF, Munroe PB, North KE, Samani NJ, Koenig W, Gaunt TR, Anand SS, van der Schouw YT, Meena Kumari on behalf of the Whitehall II Study and the WHII 50K Group , Soranzo N, Fitzgerald GA, Reiner A, Hegele RA, Hakonarson H, Keating BJ (2011). Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.. Am J Hum Genet, 88(1), 6 - 18. doi:10.1016/j.ajhg.2010.11.007
    • Taylor AE, Guthrie PA, Smith GD, Golding J, Sattar N, Hingorani AD, Deanfield JE, Day IN (2011). IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children.. Biol Psychiatry, 70(2), 152 - 158. doi:10.1016/j.biopsych.2010.10.033
    • Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH, Albrecht E, Dominiczak AF, Kerr SM, Smith BH, Cadby G, Hui J, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Ebrahim S, Smith GD, Barroso I, Loos RJ, Wareham NJ, Cooper C, Dennison E, Shaheen SO, Liu JZ, Marchini J, Medical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team , Dahgam S, Naluai AT, Olin AC, Karrasch S, Heinrich J, Schulz H, McKeever TM, Pavord ID, Heliövaara M, Ripatti S, Surakka I, Blakey JD, Kähönen M, Britton JR, Nyberg F, Holloway JW, Lawlor DA, Morris RW, James AL, Jackson CM, Hall IP, Tobin MD, SpiroMeta Consortium (2011). Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.. Am J Respir Crit Care Med, 184(7), 786 - 795. doi:10.1164/rccm.201102-0192OC
    • McKay GJ, Patterson CC, Chakravarthy U, Dasari S, Klaver CC, Vingerling JR, Ho L, de Jong PT, Fletcher AE, Young IS, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Hingorani AD, Sofat R, Dean M, Sawitzke J, Seddon JM, Peter I, Webster AR, Moore AT, Yates JR, Cipriani V, Fritsche LG, Weber BH, Keilhauer CN, Lotery AJ, Ennis S, Klein ML, Francis PJ, Stambolian D, Orlin A, Gorin MB, Weeks DE, Kuo CL, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Wright AF, Hayward C, Baird PN, Guymer RH, Attia J, Thakkinstian A, Silvestri G (2011). Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.. Hum Mutat, 32(12), 1407 - 1416. doi:10.1002/humu.21577
    • Holmes MV, Casas JP, Hingorani AD (2011). Putting genomics into practice.. BMJ, 343, d4953 - .
    • Grosso AM, Bodalia PN, Macallister RJ, Hingorani AD, Moon JC, Scott MA (2011). Cost-saving opportunities and angiotensin-II receptor blocker prescribing.. Int J Clin Pract, 65(8), 912 - . doi:10.1111/j.1742-1241.2011.02730.x
    • Grosso A, Douglas I, MacAllister R, Petersen I, Smeeth L, Hingorani AD (2011). Use of the self-controlled case series method in drug safety assessment.. Expert Opin Drug Saf, 10(3), 337 - 340. doi:10.1517/14740338.2011.562187
    • Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS) , Chakravarti A, Zhu X, Levy D (2011). Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.. Hum Mol Genet, 20(11), 2273 - 2284. doi:10.1093/hmg/ddr092
    • Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH, Albrecht E, Dominiczak AF, Kerr SM, Smith BH, Cadby G, Hui J, Palmer LJ, Hingorani AD, Wannamethee SG, Whincup PH, Ebrahim S, Smith GD, Barroso I, Loos RJ, Wareham NJ, Cooper C, Dennison E, Shaheen SO, Liu JZ, Marchini J, The NSHD Respiratory Study Team , Dahgam S, Naluai AT, Olin AC, Karrasch S, Heinrich J, Schulz H, McKeever TM, Pavord ID, Heliövaara M, Ripatti S, Surakka I, Blakey JD, Kähönen M, Britton JR, Nyberg F, Holloway JW, Lawlor DA, Morris RW, James AL, Jackson CM, Hall IP, Tobin MD, SpiroMeta Consortium (2011). Effect of 5 Genetic Variants Associated with Lung Function on the Risk of COPD, and their Joint Effects on Lung Function.. Am J Respir Crit Care Med, , - . doi:10.1164/rccm.201102-0192OC
    • Freathy RM, Kazeem GR, Morris RW, Johnson PC, Paternoster L, Ebrahim S, Hattersley AT, Hill A, Hingorani AD, Holst C, Jefferis BJ, Kring SI, Mooser V, Padmanabhan S, Preisig M, Ring SM, Sattar N, Upton MN, Vollenweider P, Waeber G, Sørensen TI, Frayling TM, Watt G, Lawlor DA, Whincup PH, Tozzi F, Davey Smith G, Munafò M (2011). Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index.. Int J Epidemiol, 40(6), 1617 - 1628. doi:10.1093/ije/dyr077
    • Holmes MV, Perel P, Shah T, Hingorani AD, Casas JP (2011). CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis.. JAMA, 306(24), 2704 - 2714. doi:10.1001/jama.2011.1880
    • Santhanakrishnan VK, Berry DJ, Hingorani AD, Whittaker JC, Jarvelin MR, Hypponen E (2011). Obesity is a Causal Risk Factor For Low Vitamin D Status: A Bi-Directional Mendelian Randomization Study on 40,000 Individuals.
    • Soler Artigas M, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspelund T, Barroso I, Campbell H, Cassano PA, Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock DB, Harris TB, Ramasamy A, Heckbert SR, Heliövaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, Lohman K, Loos RJ, Lumley T, Al Balushi KA, Ang WQ, Barr RG, Beilby J, Blakey JD, Boban M, Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Henderson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin AC, Porteous DJ, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wannamethee SG, Whincup PH, Wijmenga C, Williams OD, Wong A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietiläinen KH, Pin I, Pola Sbreve Ek O, Pouta A, Psaty BM, Hartikainen AL, Rantanen T, Ripatti S, Rotter JI, Rudan I, Rudnicka AR, Schulz H, Shin SY, Spector TD, Surakka I, Vitart V, Völzke H, Wareham NJ, Warrington NM, Wichmann HE, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N, International Lung Cancer Consortium , GIANT consortium , Kaprio J, Wilson JF, Hayward C, Kähönen M, Heinrich J, Musk AW, Jarvis DL, Gläser S, Järvelin MR, Ch Stricker BH, Elliott P, O'Connor GT, Strachan DP, London SJ, Hall IP, Gudnason V, Tobin MD (2011). Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.. Nat Genet, 43(11), 1082 - 1090. doi:10.1038/ng.941
    • McKay GJ, Silvestri G, Chakravarthy U, Dasari S, Fritsche LG, Weber BH, Keilhauer CN, Klein ML, Francis PJ, Klaver CC, Vingerling JR, Ho L, De Jong PT, Dean M, Sawitzke J, Baird PN, Guymer RH, Stambolian D, Orlin A, Seddon JM, Peter I, Wright AF, Hayward C, Lotery AJ, Ennis S, Gorin MB, Weeks DE, Kuo CL, Hingorani AD, Sofat R, Cipriani V, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Yates JR, Webster AR, Moore AT, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Young IS, Fletcher AE, Patterson CC (2011). Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people.. Am J Epidemiol, 173(12), 1357 - 1364. doi:10.1093/aje/kwr015
    • Hingorani AD, Hemingway H (2011). How should we balance individual and population benefits of statins for preventing cardiovascular disease?. BMJ, 342, c6244 - .

    2010

    • Minassian C, D'Aiuto F, Hingorani AD, Smeeth L (2010). Invasive dental treatment and risk for vascular events: a self-controlled case series.. Ann Intern Med, 153(8), 499 - 506. doi:10.7326/0003-4819-153-8-201010190-00006
    • Shah T, Newcombe P, Smeeth L, Addo J, Casas JP, Whittaker J, Miller MA, Tinworth L, Jeffery S, Strazzullo P, Cappuccio FP, Hingorani AD (2010). Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction.. Circ Cardiovasc Genet, 3(5), 436 - 444. doi:10.1161/CIRCGENETICS.110.957431
    • Hingorani AD, Shah T, Kumari M, Sofat R, Smeeth L (2010). Science, medicine, and the future Translating genomics into improved healthcare. BRIT MED J, 341, - . doi:10.1136/bmj.c5945
    • Hingorani AD, Shah T, Kumari M, Sofat R, Smeeth L (2010). Translating genomics into improved healthcare.. BMJ, 341, c5945 - .
    • Noori M, Donald AE, Angelakopoulou A, Hingorani AD, Williams DJ (2010). Prospective study of placental angiogenic factors and maternal vascular function before and after preeclampsia and gestational hypertension.. Circulation, 122(5), 478 - 487. doi:10.1161/CIRCULATIONAHA.109.895458
    • Smeeth L, Hingorani AD (2010). Short-term vascular risk: time to take notice?. Nat Rev Cardiol, 7(7), 409 - 411. doi:10.1038/nrcardio.2010.64
    • Sayers A, Timpson NJ, Sattar N, Deanfield J, Hingorani AD, Davey-Smith G, Tobias JH (2010). Adiponectin and its association with bone mass accrual in childhood.. J Bone Miner Res, 25(10), 2212 - 2220. doi:10.1002/jbmr.116
    • Howe LD, Galobardes B, Sattar N, Hingorani AD, Deanfield J, Ness AR, Davey-Smith G, Lawlor DA (2010). Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study.. Int J Obes (Lond), 34(7), 1149 - 1159. doi:10.1038/ijo.2010.52
    • Hingorani AD, Psaty BM (2010). Modeling Cardiovascular Disease Prevention Reply. JAMA-J AM MED ASSOC, 303(9), 835 - 835.
    • Welsh P, Polisecki E, Robertson M, Jahn S, Buckley BM, de Craen AJ, Ford I, Jukema JW, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Hingorani AD, Smith GD, Schaefer E, Sattar N (2010). Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach.. J Clin Endocrinol Metab, 95(1), 93 - 99. doi:10.1210/jc.2009-1064
    • Henriksson M, Palmer S, Chen R, Damant J, Fitzpatrick NK, Abrams K, Hingorani AD, Stenestrand U, Janzon M, Feder G, Keogh B, Shipley MJ, Kaski JC, Timmis A, Sculpher M, Hemingway H (2010). Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery.. BMJ, 340, b5606 - .
    • Hemingway H, Philipson P, Chen R, Fitzpatrick NK, Damant J, Shipley M, Abrams KR, Moreno S, McAllister KS, Palmer S, Kaski JC, Timmis AD, Hingorani AD (2010). Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease.. PLoS Med, 7(6), e1000286 - . doi:10.1371/journal.pmed.1000286
    • Ken-Dror G, Drenos F, Humphries SE, Talmud PJ, Hingorani AD, Kivimäki M, Kumari M, Bauer KA, Morrissey JH, Ireland HA (2010). Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.. J Thromb Haemost, 8(11), 2394 - 2403. doi:10.1111/j.1538-7836.2010.04035.x
    • Sofat R, Casas JP, Kumari M, Talmud PJ, Ireland H, Kivimaki M, Marmot M, Hughes AD, Thom S, Ebrahim S, Whittaker JC, Smeeth L, Lawlor DA, Humphries SE, Hingorani AD (2010). Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.. Atherosclerosis, 213(1), 184 - 190. doi:10.1016/j.atherosclerosis.2010.07.021
    • Casas JP, Ninio E, Panayiotou A, Palmen J, Cooper JA, Ricketts SL, Sofat R, Nicolaides AN, Corsetti JP, Fowkes FGR, Tzoulaki I, Kumari M, Brunner EJ, Kivimaki M, Marmot MG, Hoffmann MM, Winkler K, Marz W, Ye S, Stirnadel HA, Boekholdt SM, Khaw KT, Humphries SE, Sandhu MS, Hingorani AD, Talmud PJ (2010). PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry (vol 121, pg 2284, 2010). CIRCULATION, 122(3), E400 - E400. doi:10.1161/CIR.0b013e3181eb187c
    • Tsakos G, Sabbah W, Hingorani AD, Netuveli G, Donos N, Watt RG, D'Aiuto F (2010). Is periodontal inflammation associated with raised blood pressure? Evidence from a National US survey.. J Hypertens, 28(12), 2386 - 2393. doi:10.1097/HJH.0b013e32833e0fe1
    • Serrano NC, Díaz LA, Casas JP, Hingorani AD, Moreno de Lucca D, Páez MC (2010). Frequency of eNOS polymorphisms in the Colombian general population.. BMC Genet, 11, 54 - . doi:10.1186/1471-2156-11-54
    • Casas JP, Ninio E, Panayiotou A, Palmen J, Cooper JA, Ricketts SL, Sofat R, Nicolaides AN, Corsetti JP, Fowkes FG, Tzoulaki I, Kumari M, Brunner EJ, Kivimaki M, Marmot MG, Hoffmann MM, Winkler K, März W, Ye S, Stirnadel HA, Boekholdt SM, Khaw KT, Humphries SE, Sandhu MS, Hingorani AD, Talmud PJ (2010). PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.. Circulation, 121(21), 2284 - 2293. doi:10.1161/CIRCULATIONAHA.109.923383
    • Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration , Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, Saleheen D, Lawlor D, Reilly MP, Hingorani AD, Talmud PJ, Danesh J (2010). Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.. Lancet, 375(9726), 1634 - 1639. doi:10.1016/S0140-6736(10)60545-4
    • Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Magi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song KJ, Goel A, Perry JRB, Egan JM, Lajunen T, Grarup N, Sparso T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proenca C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Bottcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YDI, Chines P, Clarke R, Coin LJM, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day INM, de Geus EJC, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han XJ, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PRV, Jorgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martinez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orru M, Pakyz R, Palmer CNA, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AFH, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurosson G, Sijbrands EJG, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvanen AC, Tanaka T, Thorand B, Tichet J, Tonjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JCM, Yarnell JWG, Zeggini E, Zelenika D, Zethelius B, Zhai GJ, Zhao JH, Zillikens MC, Borecki IB, Loos RJF, Meneton P, Magnusson PKE, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Rios M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WHL, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF, Hamsten A, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BWJH, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, DIAGRAM Consortium , GIANT Consortium , Global BPgen Consortium , Procardis Consortium , Ines Barroso MAGIC Investigators (2010). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010). NAT GENET, 42(5), 464 - 464. doi:10.1038/ng0510-464a
    • Donald AE, Charakida M, Falaschetti E, Lawlor DA, Halcox JP, Golding J, Hingorani AD, Smith GD, Deanfield JE (2010). Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC).. Eur Heart J, 31(12), 1502 - 1510. doi:10.1093/eurheartj/ehq062
    • Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A, Zhai G, Vitart V, Huffman JE, Igl W, Albrecht E, Deloukas P, Henderson J, Granell R, McArdle WL, Rudnicka ARWTCCC, et A (2010). Genome-wide association study identifies five loci associated with lung function. Nature Genetics, 42(1), 36 - 44. doi:10.1038/ng.501
    • Sofat R, Hingorani AD, Smeeth L, Humphries SE, Talmud PJ, Cooper J, Shah T, Sandhu MS, Ricketts SL, Boekholdt SM, Wareham N, Khaw KT, Kumari M, Kivimaki M, Marmot M, Asselbergs FW, van der Harst P, Dullaart RP, Navis G, van Veldhuisen DJ, Van Gilst WH, Thompson JF, McCaskie P, Palmer LJ, Arca M, Quagliarini F, Gaudio C, Cambien F, Nicaud V, Poirer O, Gudnason V, Isaacs A, Witteman JC, van Duijn CM, Pencina M, Vasan RS, D'Agostino RB, Ordovas J, Li TY, Kakko S, Kauma H, Savolainen MJ, Kesaniemi YA, Sandhofer A, Paulweber B, Sorli JV, Goto A, Yokoyama S, Okumura K, Horne BD, Packard C, Freeman D, Ford I, Sattar N, McCormack V, Lawlor DA, Ebrahim S, Smith GD, Kastelein JJ, Deanfield J, Casas JP (2010). Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation, 121, 52 - 62.
    • Falaschetti E, Hingorani AD, Jones A, Charakida M, Finer N, Whincup P, Lawlor DA, Davey Smith G, Sattar N, Deanfield JE (2010). Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children.. Eur Heart J, 31(24), 3063 - 3072. doi:10.1093/eurheartj/ehq355
    • Yiannakouris N, Cooper JA, Shah S, Ireland H, Stephens JW, Li KW, Elkeles R, Godsland I, Kivimaki M, Hingorani AD, Talmud PJ, Kumari M, Humphries SE (2010). Genetic variants near IRS1 and their association with type 2 diabetes, hyperinsulinemia and insulin resistance. DIABETES OBES METAB, 12, 46 - 46.
    • Langenberg C, Jensen AC, Barker A, Brunner EJ, Hingorani AD, Kumari M, Kivimaki M, Wareham NJ, Tabak AG, Witte DR (2010). Age-dependent genetic effects on post-load glucose during 18 years of follow-up of the Whitehall II Cohort.
    • Mayahi L, Mason L, Bleasdale-Barr K, Donald A, Trender-Gerhard I, Sweeney MG, Davis MB, Wood N, Mathias CJ, Watson L, Pellerin D, Heales S, Deanfield JE, Bhatia K, Murray-Rust J, Hingorani AD (2010). Endothelial, Sympathetic, and Cardiac Function in Inherited (6R)-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin Deficiency. CIRC-CARDIOVASC GENE, 3(6), 513 - 522. doi:10.1161/CIRCGENETICS.110.957605

    2009

    • Hingorani AD, Psaty BM (2009). Primary prevention of cardiovascular disease: time to get more or less personal?. JAMA, 302(19), 2144 - 2145. doi:10.1001/jama.2009.1698
    • Kuper H, Nicholson A, Kivimaki M, Aitsi-Selmi A, Cavalleri G, Deanfield JE, Heuschmann P, Jouven X, Malyutina S, Mayosi BM, Sans S, Thomsen T, Witteman JC, Hingorani AD, Lawlor DA, Hemingway H (2009). Evaluating the causal relevance of diverse risk markers: horizontal systematic review.. BMJ, 339, b4265 - .
    • Drenos F, Talmud PJ, Casas JP, Smeeth L, Palmen J, Humphries SE, Hingorani AD (2009). Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. HUM MOL GENET, 18(12), 2305 - 2316. doi:10.1093/hmg/ddp159
    • Shah T, Casas JP, Cooper JA, Tzoulaki I, Sofat R, McCormack V, Smeeth L, Deanfield JE, Lowe GD, Rumley A, Fowkes FGR, Humphries SE, Hingorani AD (2009). Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts (vol 38, pg 217, 2009). INT J EPIDEMIOL, 38(3), 890 - 890. doi:10.1093/ije/dyp206
    • Bellamy L, Casas JP, Hingorani AD, Williams D (2009). Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. LANCET, 373(9677), 1773 - 1779.
    • O'Neill SG, Pego-Reigosa JM, Hingorani AD, Bessant R, Isenberg DA, Rahman A (2009). Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus.. Rheumatology (Oxford), 48(5), 573 - 575. doi:10.1093/rheumatology/kep037
    • Newcombe PJ, Verzilli C, Casas JP, Hingorani AD, Smeeth L, Whittaker JC (2009). Multilocus Bayesian meta-analysis of gene-disease associations.. Am J Hum Genet, 84(5), 567 - 580. doi:10.1016/j.ajhg.2009.04.001
    • Sattar N, Hingorani AD (2009). C-reactive protein and prognosis in diabetes: getting to the heart of the matter.. Diabetes, 58(4), 798 - 799. doi:10.2337/db08-1788
    • Hingorani AD, Shah T, Casas JP, Humphries SE, Talmud PJ (2009). C-reactive protein and coronary heart disease: predictive test or therapeutic target?. Clin Chem, 55(2), 239 - 255. doi:10.1373/clinchem.2008.115923
    • Holmes MV, Shah T, Vickery C, Smeeth L, Hingorani AD, Casas JP (2009). Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.. PLoS One, 4(12), e7960 - . doi:10.1371/journal.pone.0007960
    • Shah S, Drenos F, Shah T, Palmen J, Vezzili C, Sofat R, Kumari M, Kivamaki M, Pallas J, MacFarlane P, Whittaker J, Talmud PJ, Humphries SE, Hingorani AD (2009). IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY. doi:10.1016/j.atherosclerosis.2009.09.058
    • Holmes MV, Shah T, Vickery C, Smeeth L, Hingorani AD, Casas JP (2009). A FIELD SYNOPIS OF PHARMACOGENETIC STUDIES. doi:10.1016/j.atherosclerosis.2009.09.041
    • Shah T, Newcombe P, Addo J, Casas JP, Smeeth L, Whittaker J, Hingorani AD (2009). CONSIDERATION OF ETHNICITY IN CORONARY RISK PREDICTION USING CRP. doi:10.1016/j.atherosclerosis.2009.09.059
    • Shah T, Casas JP, Cooper JA, Tzoulaki I, Sofat R, McCormack V, Smeeth L, Deanfield JE, Lowe GD, Rumley A, Fowkes FG, Humphries SE, Hingorani AD (2009). Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts.. Int J Epidemiol, 38(1), 217 - 231. doi:10.1093/ije/dyn217
    • Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. American Journal of Human Genetics, 85, 628 - 642.
    • Grosso A, Douglas I, Hingorani AD, MacAllister R, Hubbard R, Smeeth L (2009). Inhaled tiotropium bromide and risk of stroke.. Br J Clin Pharmacol, 68(5), 731 - 736. doi:10.1111/j.1365-2125.2009.03517.x

    2008

    • Savvidou MD, Noori M, Anderson JM, Hingorani AD, Nicolaides KH (2008). Maternal endothelial function and serum concentrations of placental growth factor and soluble endoglin in women with abnormal placentation.. Ultrasound Obstet Gynecol, 32(7), 871 - 876. doi:10.1002/uog.6126
    • Grosso A, Douglas I, Hingorani A, Macallister R, Smeeth L (2008). Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions.. British Journal of Clinical Pharmacology, , - . doi:10.1111/j.1365-2125.2008.03273.x
    • Verzilli C, Shah T, Casas JP, Chapman J, Sandhu M, Debenham SL, Boekholdt MS, Khaw KT, Wareham NJ, Judson R, Benjamin EJ, Kathiresan S, Larson MG, Rong J, Sofat R, Humphries SE, Smeeth L, Cavalleri G, Whittaker JC, Hingorani AD (2008). Bayesian meta-analysis of genetic association studies with different sets of markers. AM J HUM GENET, 82(4), 859 - 872. doi:10.1016/j.ajhg.2008.01.016
    • Talmud PJ, Cooper JA, Palmen J, Lovering R, Drenos F, Hingorani AD, Humphries SE (2008). Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.. Clin Chem, 54(3), 467 - 474. doi:10.1373/clinchem.2007.095489
    • D'Aiuto F, Sabbah W, Netuveli G, Donos N, Hingorani AD, Deanfield J, Tsakos G (2008). Association of the metabolic syndrome with severe periodontitis in a large U.S. population-based survey. Journal of Clinical Endocrinology and Metabolism, 93(10), 3989 - 3994.
    • Shah T, Casas JP, Cooper JA, Tzoulaki I, Sofat R, Smeeth L, Deanfield JE, Lowe GD, Rumley A, Fowkes FGR, Humphries SE, Hingorani AD (2008). CRITICAL APPRAISAL OF THE UTILITY OF CRP MEASUREMENT IN THE PREDICTION OF CARDIOVASCULAR EVENTS. ATHEROSCLEROSIS SUPP, 9(1), 10 - 10.
    • Brunner EJ, Kivimäki M, Witte DR, Lawlor DA, Smith GD, Cooper JA, Miller M, Lowe GD, Rumley A C, J P S, T H, S E H, A D M, M G T, N J K, M (2008). Inflammation, Insulin Resistance, and Diabetes -Mendelian Randomization Using CRP Haplotypes Points Upstream.. PLoS Medicine, 5(8), e155 - .
    • Kivimaki M, Lawlor DA, Smith GD, Kumari M, Donald A, Britton A, Casas JP, Shah T, Brunner E, Timpson NJ, Halcox JP, Miller MA, Humphries SE, Deanfield J, Marmot MG, Hingorani AD (2008). Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study. , 3, e3013 - .
    • Casas JP, Shah T, Hingorani AD, Danesh J, Pepys MB (2008). C-reactive protein and coronary heart disease: a critical review. J Intern Med, 264(4), 295 - 314.
    • Clarke R, Emberson JR, Breeze E, Casas JP, Parish S, Hingorani AD, Fletcher A, Collins R, Smeeth L (2008). Biomarkers of inflammation predict both vascular and non-vascular mortality in older men. , 29, 800 - 809.
    • Hingorani AD, D'Aiuto F (2008). Chronic inflammation, periodontitis and cardiovascular diseases. Oral Diseases, 14(2), 102 - 104.

    2007

    • Bellamy L, Casas JP, Hingorani AD, Williams DJ (2007). Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BRIT MED J, 335(7627), 974 - 977. doi:10.1136/bmj.39335.85301.BE
    • Mayahi L, Heales S, Owen D, Casas JP, Harris J, MacAllister RJ, Hingorani AD (2007). (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm.. Arterioscler Thromb Vasc Biol, 27(6), 1334 - 1339. doi:10.1161/ATVBAHA.107.142257
    • Smeeth L, Casas JP, Hingorani AD (2007). The role of infection in cardiovascular disease: more support but many questions remain. EUR HEART J, 28(10), 1178 - 1179. doi:10.1093/eurheartj/ehm035
    • Ariyaratnam R, Casas JP, Whittaker J, Smeeth L, Hingorani AD, Sharma P (2007). Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals.. PLoS Med, 4(4), e131 - . doi:10.1371/journal.pmed.0040131
    • Noori M, Donald A, Hingorani A, Williams DJ (2007). A prospective study of maternal endothelial function, angiogenic factors and placental function in women at risk of pre-eclampsia..
    • Bellamy L, Casas JP, Hingorani AD, Williams DJ (2007). Pre-eclampsia and the risk of cardiovascular disease and cancer in later life: a systematic review and meta-analysis.. BMJ (Clinical Research Ed.), 335(7627), 974 - 977.
    • Smeeth L, Casas JP, Hingorani AD (2007). The role of infection in cardiovascular disease: more support but many questions remain.. Eur Heart J, 28(10), 1178 - 1179. doi:10.1093/eurheartj/ehm073
    • Tonetti MS, D'Aiuto F, Nibali L, Donald A, Storry C, Parkar MH, Suvan JE, Hingorani AD, Vallance P, Deanfield J (2007). Treatment of periodontitis and endothelial function. New England Journal of Medicine, 356(9), 911 - 920. doi:10.1056/NEJMoa063186
    • Sharma P, Whittaker J, Casas JP, Hingorani AD, Ariyaratnam R (2007). Genetics of ischaemic stroke in ethnic minorities.
    • Tzoulaki I, Shah T, Ireland H, Casas JP, Hingorani AD, Humphries SE, Fowkes FGR (2007). C-reactive protein and interleukin-6 polymorphisms in relation to subclinical atherosclerotic disease.

    2006

    • Mayahi L, Mason L, Storry C, Donald A, Trender-Gherhard I, Mathias C, Deanfield J, Bhatia K, Heales S, Pellerin D, Hingorani A (2006). Endothelial, sympathetic and cardiac function in inherited 6R-L-Erythro-5,6,7,8-Tetrahydro-L-Biopterin deficiency. Circulation, 114(18), 283 - 283.
    • Humphries SE, Hingorani A (2006). Pharmacogenetics: Progress, pitfalls and clinical potential for coronary heart disease.. Vascular Pharmacology, 44(2), 119 - 125.
    • Casas JP, Hingorani AD, MacAllister RJ, Smeeth L (2006). Progression of renal disease - can we forget about inhibition of the renin-angiotensin system? Authors' reply. NEPHROL DIAL TRANSPL, 21(9), 2352 - 2353. doi:10.1093/ndt/gfl316
    • Savvidou MD, Yu CK, Harland LC, Hingorani AD, Nicolaides KH (2006). Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction.. Am J Obstet Gynecol, 195(6), 1668 - 1673. doi:10.1016/j.ajog.2006.03.065
    • Serrano NC, Díaz LA, Páez MC, Mesa CM, Cifuentes R, Monterrosa A, González A, Smeeth L, Hingorani AD, Casas JP (2006). Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias.. PLoS Med, 3(12), e520 - . doi:10.1371/journal.pmed.0030520
    • Casas JP, Cavalleri GL, Bautista LE, Smeeth L, Humphries SE, Hingorani AD (2006). Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review.. Am J Epidemiol, 164(10), 921 - 935. doi:10.1093/aje/kwj302
    • Bautista LE, Smeeth L, Hingorani AD, Casas JP (2006). Estimation of bias in nongenetic observational studies using "mendelian triangulation".. Ann Epidemiol, 16(9), 675 - 680. doi:10.1016/j.annepidem.2006.02.001
    • Casas JP, Vallance P, Smeeth L, Hingorani AD, MacAllister RJ (2006). Renoprotective effects of renin-angiotensin-system inhibitors - Reply. LANCET, 367(9514), 900 - 902.
    • Shah T, Cooper JA, Casas JP, Pearce K, Tinworth L, Hingorani AD, Miller GJ, Humphries SE (2006). CRP in the prediction and pathogenesis of cardiovascular events in middle-aged men; Results from the NPHSII study.
    • Hingorani AD, Shah T, Casas JP (2006). Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk.. Eur Heart J, 27(11), 1261 - 1263. doi:10.1093/eurheartj/ehi852
    • Alves JD, Clapp BR, Stidwill R, Chen PP, Hingorani AD, Singer M, Isenberg DA (2006). Human monoclonal IgG anticardiolipin antibodies induce nitric oxide synthase expression.. Atherosclerosis, 185(2), 246 - 253. doi:10.1016/j.atherosclerosis.2005.06.044
    • Yu CK, Casas JP, Savvidou MD, Sahemey MK, Nicolaides KH, Hingorani AD (2006). Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis.. BMC Pregnancy Childbirth, 6, 7 - . doi:10.1186/1471-2393-6-7
    • Casas JP, Shah T, Cooper J, Hawe E, McMahon AD, Gaffney D, Packard CJ, O'Reilly DS, Juhan-Vague I, Yudkin JS, Tremoli E, Margaglione M, Di Minno G, Hamsten A, Kooistra T, Stephens JW, Hurel SJ, Livingstone S, Colhoun HM, Miller GJ, Bautista LE, Meade T, Sattar N, Humphries SE, Hingorani AD (2006). Insight into the nature of the CRP-coronary event association using Mendelian randomization.. Int J Epidemiol, 35(4), 922 - 931. doi:10.1093/ije/dyl041
    • Casas JP, Cooper J, Miller GJ, Hingorani AD, Humphries SE (2006). Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies. , 70, 145 - 169.
    • Hingorani AD, Shah T, Casas JP (2006). Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk. EUR HEART J, 27(11), 1261 - 1263. doi:10.1193/eurheart/ehl852

    2005

    • D'Aiuto F, Casas JP, Shah T, Humphries SE, Hingorani AD, Tonetti MS (2005). C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus.. Atherosclerosis, 179(2), 413 - 417. doi:10.1016/j.atherosclerosis.2004.10.036
    • Casas JP, Chua W, Loukogeorgakis S, Vallance P, Smeeth L, Hingorani AD, MacAllister RJ (2005). Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis.. The Lancet, 366(9502), 2026 - 2033. doi:10.1016/S0140-6736(05)67814-2
    • Jones LC, Hingorani AD (2005). Genetic regulation of endothelial function.. Heart, 91(10), 1275 - 1277. doi:10.1136/hrt.2005.061325
    • Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD (2005). Homocysteine and stroke: evidence on a causal link from mendelian randomisation. , 365, 224 - 232.
    • Bautista LE, Casas JP, Smeeth L, Hingorani AD (2005). Estimation of bias in "Mendelian triangulation" studies..
    • Clapp BR, Hirschfield GM, Storry C, Gallimore JR, Stidwill RP, Singer M, Deanfield JE, MacAllister RJ, Pepys MB, Vallance P, Hingorani AD (2005). Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability. Circulation, 111(12), 1530 - 1536. doi:10.1161/01.CIR.0000159336.31613.31
    • Shah T, Casas J, Cooper J, Hawe E, Stephens J, Hurel S, Yudkin J, Livingstone S, Colhoun H, Bautista L, Meade T, Gaffney D, McMahon A, Hamsten A, Sattar N, Humphries SE, Hingorani AD (2005). Mendelian randomisation and disease risk estimates for C-reactive protein (CRP).

    2004

    • Hingorani A (2004). Resolving inconsistency in the results of genetic association studies of cardiovascular disease.. Clinical Science, 107(3), 251 - 253.
    • Bessant R, Hingorani A, Patel L, MacGregor A, Isenberg DA, Rahman A (2004). Risk of coronary heart disease and stroke in a large British cohort of patients with systemic lupus erythematosus.. Rheumatology, 43(7), 924 - 929.
    • Casas JP, Bautista LE, Humphries SE, Hingorani AD (2004). Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects.. Circulation, 109(11), 1359 - 1365. doi:10.1161/01.CIR.0000121357.76910.A3
    • Alves JD, Clapp BR, Stidwill R, Chen PP, Hingorani AD, Singer M, Isenberg DA (2004). Human monoclonal IGG anticardiolipin antibodies induce nitric oxide synthase expression.
    • MacAllister R, Hingorani AD, Casas JP (2004). Ximelagatran or warfarin in atrial fibrillation?. , 363, 735 - 736.
    • Casas JP, Hingorani AD, Bautista LE, Sharma P (2004). Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.. Archives of Neurology, 61(11), 1652 - 1661.
    • Serrano NC, Casas JP, Diaz LA, Paez C, Mesa CM, Cifuentes R, Monterrosa A, Bautista A, Hawe E, Hingorani AD, Vallance P, Lopez-Jaramillo P (2004). Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study.. Hypertension, 44(5), 702 - 707.
    • Clapp BR, Hingorani AD, Kharbanda RK, Mohamed-Ali V, Stephens JW, Vallance P, MacAllister RJ (2004). Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.. Cardiovascular Research, 64(1), 172 - 178.
    • Casas JP, Hingorani AD, Humphries SE, Smeeth L, Bautista LE (2004). Do meta-analyses of association studies of endothelial nitric oxide synthase variants and ischemic heart disease provide conclusive answers? Response. CIRCULATION, 110(11), E305 - E306.
    • Casas JP, Bautista LE, Hingorani AD, Sharma P (2004). Plasma homocysteine, and ischaemic stroke: "Mendelian randomization" provides further evidence of causal link.
    • Healy DG, Abou-Sleiman PM, Lees AJ, Casas JP, Quinn N, Bhatia K, Hingorani AD, Wood NW (2004). Tau gene and Parkinson's disease: a case-control study and meta-analysis. , 75, 962 - 965.
    • Hingorani AD (2004). Diet, the endothelium and atherosclerosis.. Clin Sci (Lond), 106(5), 447 - 448. doi:10.1042/CS20040023

    2003

    • Clapp B, Hirschfield G, MacAllister R, Gallimore R, Vallance P, Pepys M, Hingorani A (2003). C-reactive protein alters vascular reactivity by increasing nitric oxide production.
    • Jones LC, Tran CT, Leiper JM, Hingorani AD, Vallance P (2003). Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells. Biochemical and Biophysical Research Communications, 310(3), 836 - 843.
    • Brull DJ, Serrano N, Zito F, Jones L, Montgomery HE, Rumley A, Sharma P, Lowe GDO, World MJ, Humphries SE, Hingorani AD (2003). A polymorphism in the human CRP gene influences basal and stimulated CRP levels: Implications for the prediction and pathogenesis of coronary heart disease.
    • Brull DJ, Serrano N, Zito F, Jones L, Montgomery HE, Rumley A, Sharma P, Lowe GDO, World MJ, Humphries SE, Hingorani AD (2003). A polymorphism in the human CRP gene influences basal and stimulated CRP levels: Implications for the prediction and pathogenesis of coronary heart disease.
    • Brull DJ, Serrano N, Zito F, Jones L, Montgomery HE, Rumley A, Sharma P, Lowe GD, World MJ, Humphries SE, Hingorani AD (2003). Human CRP gene polymorphism influences CRP levels: implications for the prediction and pathogenesis of coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 23(11), 2063 - 2069.
    • Hingorani AD (2003). Endothelial nitric oxide synthase polymorphisms and hypertension. Current Hypertension Reports, 5(1), 19 - 25.
    • Savvidou MD, Hingorani AD, Tsikas D, Frolich JC, Vallance P, Nicolaides KH (2003). Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. The Lancet, 361(9368), 1511 - 1517. doi:10.1016/S0140-6736(03)13177-7

    2002

    • Leeson CP, Hingorani AD, Mullen MJ, Jeerooburkhan N, Kattenhorn M, Cole TJ, Muller DP, Lucas A, Humphries SE, Deanfield JE (2002). Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. Circulation Research, 90(11), 1153 - 1158. doi:10.1161/01.RES.0000020562.07492.D4
    • (2002). Prevention of inflammation-induced endothelial dysfunction - A novel vasculo-protective action of aspirin. Circulation, 105(22), 2600 - 2604. doi:10.1161/01.CIR.0000017863.52347.6C
    • Savvidou MD, Lees CC, Parra M, Hingorani AD, Nicolaides KH (2002). Levels of C-reactive protein in pregnant women who subsequently develop pre-eclampsia. British Journal of Obstetrics and Gynaecology, 109(3), 297 - 301.
    • Chan NN, Vallance P, Colhoun HM, MacAllister RJ, Hingorani AD, Conway GS (2002). The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome. Clinical Endocrinology, 56(5), 615 - 620.

    2001

    • Jeerooburkhan N, Jones LC, Bujac S, Cooper JA, Miller GJ, Vallance P, Humphries SE, Hingorani AD (2001). Genetic and environmental determinants of plasma nitrogen oxides and risk of ischemic heart disease. Hypertension, 38(5), 1054 - 1061.
    • Hingorani AD, Chan NN (2001). D-lactate encephalopathy. The Lancet, 358(9295), 1814 - .
    • Hingorani AD (2001). Polymorphisms in endothelial nitric oxide synthase and atherogenesis: John French Lecture 2000. Atherosclerosis, 154(3), 521 - 527.
    • Chan NN, MacAllister RJ, Colhoun HM, Vallance P, Hingorani AD (2001). Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. Journal of Clinical Endocrinology and Metabolism, 86(6), 2499 - 2504.
    • (2001). The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function Leeson CP,. Circulation, 102(18), 1366 - .
    • Savvidou MD, Vallance PJ, Nicolaides KH, Hingorani AD (2001). Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy. Hypertension, 38(6), 1289 - 1293.

    2000

    • Vallance P, Hingorani AD, Ulrich S (2000). Optimal age for starting lipid lowering treatment - Adjusted data do not justify a lower optimal age - Reply. BRIT MED J, 321(7261), 638 - 638.
    • Chan NN, Vallance PJ, Macallister RJ, Hingorani AD, Colhoun HM (2000). Impaired nitric oxide response in resistance vessels in human type 1 diabetes in vivo. CIRCULATION, 102(18), 326 - 326.
    • Leeson CP, Hingorani AD, Mullen MJ, Jeerooburkhan N, Kattenhorn M, Muller DP, Lucas A, Humphries SE, Deanfield JE (2000). The Glu298-Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. CIRCULATION, 102(18), 279 - 279.
    • Ulrich S, Hingorani AD, Martin J, Vallance P (2000). What is the optimal age for starting lipid lowering treatment? A mathematical model. BMJ (Clinical Research Ed.), 320(7242), 1134 - 1140.
    • Hingorani AD, Cross J, Kharbanda RK, Mullen MJ, Bhagat K, Taylor M, Donald AE, Palacios M, Griffin GE, Deanfield JE, MacAllister RJ, Vallance P (2000). Acute systemic inflammation impairs endothelium-dependent dilatation in humans. Circulation, 102(9), 994 - 999.

    1999

    • Hingorani AD, Bhagat K, Palacios M, Griffin GE, MacAllister RJ, Vallance P (1999). Acute systemic inflammation impairs endothelium-dependent dilatation in humans. BRIT J PHARMACOL, 126, U31 - U31.
    • Jia H, Hingorani AD, Sharma P, Hopper R, Dickerson C, Trutwein D, Lloyd DD, Brown MJ (1999). Association of the G(s)alpha gene with essential hypertension and response to beta-blockade. Hypertension, 34(1), 8 - 14.
    • Dickerson JE, Hingorani AD, Ashby MJ, Palmer CR, Brown MJ (1999). Optimisation of antihypertensive treatment by crossover rotation of four major classes. The Lancet, 353(9169), 2008 - 2013.
    • Hingorani AD, Vallance P (1999). A simple computer program for guiding management of cardiovascular risk factors and prescribing [see comments]. BMJ (Clinical Research Ed.), 318(7176), 101 - 105.
    • Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, Haydock S, Hopper RV, Stephens NG, O'Shaughnessy KM, Brown MJ (1999). A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK. Circulation, 100(14), 1515 - 1520.
    • Hingorani AD, Cross JM, Kharbanda RK, Mullen MJ, Bhagat K, Taylor M, Donald AE, Palacios-Callende M, Griffin GE, Deanfield JE, Raymond MJ, Vallance P (1999). Acute systemic inflammation impairs endothelium-dependent dilation in humans. CIRCULATION, 100(18), 48 - 48.
    • Hingorani AD, Vallance P (1999). Hypothesis of program is flawed - Reply. BRIT MED J, 318(7195), 1419 - 1419.
    • Chen Z, Ahluwalia A, Selwood DL, Vallance P, Hingorani AD (1999). Enhancement of endothelium-dependent vasodilatation by oestradiol 17-beta: Role of the pterin pathway. BRIT J PHARMACOL, 126, U32 - U32.
    • Ulrich S, Hingorani A, Martin J, Vallance P (1999). What is the optimal age for starting lipid lowering treatment? A mathematical model.. BMJ (Clinical Research Ed.), 320, 1134 - 1140.
    • Ulrich S, Hingorani A, Martin J, Vallance P (1999). Lifetime risk of developing coronary heart disease. The Lancet, 353, 925 - .
    • Bhagat K, Hingorani AD, Palacios M, Charles IG, Vallance P (1999). Cytokine-induced venodilatation in humans in vivo: eNOS masquerading as iNOS. Cardiovascular Research, 41(3), 754 - 764.

    1998

    • Sharma P, Hingorani A, Jia H, Ashby M, Hopper R, Clayton D, Brown MJ (1998). Positive association of tyrosine hydroxylase microsatellite marker to essential hypertension. HYPERTENSION, 32(4), 676 - 682.

    1997

    • Bhagat K, Hingorani A, Vallance P (1997). Flow associated or flow mediated dilatation? More than just semantics. Heart, 78(1), 7 - 8.
    • Hingorani AD, O'Hanlon S, Halloran SP, Wright JP, Foley TH (1997). Evaluation of a paired creatine kinase test for the diagnosis of acute myocardial infarction in patients with a non-diagnostic electrocardiogram. J ACCID EMERG MED, 14(3), 134 - 138.
    • Hingorani AD, Liang CF, Fatibene J, Parsons A, Hopper RV, Trutwein D, Stephens NG, OShaughnessy KM, Brown MJ (1997). A common variant of the endothelial nitric oxide synthase gene is a risk factor for coronary atherosclerosis in the east Anglian region of the UK. CIRCULATION, 96(8), 3050 - 3050.

    1996

    • Hingorani AD, Brown MJ (1996). A simple molecular assay for the C-1166 variant of the angiotensin II type 1 receptor gene (vol 213, pg 725, 1995). BIOCHEM BIOPH RES CO, 218(1), 420 - 420.
    • Hingorani AD, Brown MJ (1996). Identifying the genes for human hypertension.. Nephrol Dial Transplant, 11(4), 575 - 586.
    • Hingorani AD, Sharma P, Jia H, Hopper R, Brown MJ (1996). Blood pressure and the M235T polymorphism of the angiotensinogen gene.. Hypertension, 28(5), 907 - 911.

    1995

    • Hingorani AD, Foley TH (1995). Non-sustained broad-complex tachycardia following intravenous adenosine.. J Accid Emerg Med, 12(3), 208 - 209.
    • Hingorani AD, Brown MJ (1995). A simple molecular assay for the C1166 variant of the angiotensin II type 1 receptor gene.. Biochem Biophys Res Commun, 213(2), 725 - 729. doi:10.1006/bbrc.1995.2190
    • Hingorani AD, Bloomberg TJ (1995). Ultrasound-guided pigtail catheter drainage of malignant pericardial effusions.. Clin Radiol, 50(1), 15 - 19.
    • Hingorani AD, Jia H, Stevens PA, Hopper R, Dickerson JE, Brown MJ (1995). Renin-angiotensin system gene polymorphisms influence blood pressure and the response to angiotensin converting enzyme inhibition.. J Hypertens, 13(12 Pt 2), 1602 - 1609.

    1994

    • HINGORANI AD, JONES AT, DZIERSK J, GOLDINGWOOD D, LEIGH JM (1994). ADULT EPIGLOTTITIS - ESTABLISH AN AIRWAY EARLY. BRIT MED J, 308(6930), 719 - 719.

    1993

    • Hingorani AD, Ainsworth RW (1993). Pulmonary microembolisation and temazepam.. BMJ, 307(6904), 623 - 624.
    • Hingorani AD, Macdougall IC, Browne M, Walker RW, Tomson CR (1993). Successful treatment of acute D-lactate encephalopathy by haemodialysis.. Nephrol Dial Transplant, 8(11), 1283 - 1285.
    • Hingorani AD (1993). The flosequinan experience and its implications.. Br J Hosp Med, 50(11), 683 - .

    1992

    • Hingorani AD (1992). Postinfectious myocarditis.. BMJ, 304(6843), 1676 - 1678.
    • HINGORANI AD, DOLLERY CT, OAKLEY CM, BLOOM SR, COHEN J (1992). HAMMERSMITH STAFF ROUNDS - POSTINFECTIOUS MYOCARDITIS. BRIT MED J, 304(6843), 1676 - 1678.

    • Gertow K, Sennblad B, Strawbridge R, Ohrvik J, Zabeneh D, Shah S, Veglia F, Fava C, Kavousi M, Kivimaki M, Bolton J, Fokersen L, Gigante B, Leander K, Vikstrom M, Larsson , Silveira A, Deanfield J, Voight BF, Fontanillas P, Sabater-Lleal M, Colombo G, Kumari M, Langenberg C, Wareham N, Uitterlinder A, Gabrielsen A, Hedin U, Franco-Cereceda A, Nyyssoen K, Rauramaa R, Tuomainen T, Savonen K, Smit A, Giral P, Mannarino E, Robertson C, Talmud PJ, Hedblad B, Hofman A, Erdmann J, Reilly MP, Grazia Franzosi MG, Seedorf U, Syvanen AC, Hansson GK, Eriksson P, Samani NJ, Watkins H, Price JF, Hingorani AD, Melander O, Witterman JCM, Baldassaree D, Tremoli E, de Faire U, Hamsten A, Humphries SE (). Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-medial thickness and coronary artery disease. Circulation: Cardiovascular Genetics, , - .
    • Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, et A (). New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.. Nature Genetics, , - .
    • Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, Stringham HM, Prokopenko I, Johnson T, Grarup N, Boesgaard TW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K, Andreasen CH, Dina C, Köttgen A, Le Bacquer O, Pattou F, Taneera J, Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN, Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Buchanan TA, Bumpstead SJ, Cavalcanti-Proença C, Charpentier G, Chen YD, Chines PS, Collins FS, Cornelis M, J Crawford G, Delplanque J, Doney A, Egan JM, Erdos MR, Firmann M, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, Jørgensen T, Kivimaki M, Kovacs P, Krohn K, Kumari M, et A (). Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.. Nature Genetics, , - .
    • Talmud PJ, Hingorani AD, Cooper JA, Marmot MG, Brunner EJ, Kumari M, Kivimäki M, Humphries SE (). Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.. British Medical Journal, , - .