Prof David Skuse

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Personal Profile

Name: David Skuse Email: d.skuse@ucl.ac.uk
Title: Prof Tel: 020 7905 2712
Department: ICH Pop, Policy & Practice Prog Fax: 020 7831 7050
Position: Chair of Behavioural and Brain Sciences Address: Behavioural Sciences Unit, Institute of Child Health, UCL, 30 Guilford St, London, WC1N 1EH
Research Domain: Neuroscience, Populations & Lifelong Health Web Page:  

Profile

Research Description

Research led by David Skuse in the Behavioural and Brain Sciences Unit falls into three main themes:

First, the study of clinical groups with impairment of social communication, in collaboration with the clinical team in the Social Communication Disorders Clinic at Great Ormond Street Hospital. This comprises a number of genetic, cognitive and physiological studies of children with Autism Spectrum Disorders.

Second, the study of typical populations both in the UK and overseas, examining normal variation in social perception and social decision making. Our focus is on individual differences that relate to genetic variants in the general population. Research is highly interdisciplinary and collaborative, incorporating the study of endophenotypes through neuroimaging and ERP among other techniques.

Third, the study of atypical populations with social communication deficits, in everyday situations. This is an emerging theme, in collaboration with the Computer Science Department at UCL, incorporating the development of novel measures of activity, autonomic responsiveness and global positioning.

Research Activities

Autism Spectrum Disorders

Biological influences on social competence, and neurodevelopmental disorders of social cognition

Education Description

Teaching activities undertaken by David Skuse and his team fall into three main categories:

First, PhD studentships, including UCL Grand Challenge and Crucible students. These are cross-cutting in concept, linking faculties and building collaborations to bring new perspectives on questions about the origins, and management, of neurodevelopmental differences.

Second, training in clinical assessment in collaboration with the Centre for High Functioning Autism at Great Ormond Street Hospital. Courses are run locally and nationally on the Autism Diagnostic Observation Schedule, and the Developmental, Dimensional and Diagnostic Interview (3Di).

Third, an MSc in Child and Adolescent Mental Health. This course incorporates the option for a clinical placement at Great Ormond Street Hospital or the Tavistock Clinic. It is one of only two such courses in the UK, and welcomes those who are interested in a career in clinical psychology or child psychiatry, or an allied profession.

UCL Collaborators

Prof Sarah-Jayne Blakemore; Prof Neil Marlow; Prof Essi Viding; Dr William Mandy; Prof Paul Burgess; Prof Brian Butterworth

External Collaborators

Publications

    2014

    • Skuse D (2014). OXYTOCIN AND SOCIAL COGNITION. doi:10.1136/jnnp-2014-308883.1
    • St Pourcain B, Skuse DH, Mandy WP, Wang K, Hakonarson H, Timpson NJ, Evans DM, Kemp JP, Ring SM, McArdle WL, Golding J, Smith GD (2014). Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.. Mol Autism, 5(1), 18 - . doi:10.1186/2040-2392-5-18
    • Skuse DH, Lori A, Cubells JF, Lee I, Conneely KN, Puura K, Lehtimaki T, Binder EB, Young LJ (2014). Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(5), 1987 - 1992. doi:10.1073/pnas.1302985111

    2013

    • Ricotti V, Scoto M, Mandy W, Entwistle K, Robb A, Pane M, Mercuri E, Skuse D, Muntoni F (2013). Neuropsychiatric comorbidities in Duchenne Muscular Dystrophy. doi:10.1016/j.nmd.2013.06.418
    • Mandy W, Skuse D, Steer C, St Pourcain B, Oliver BR (2013). Oppositionality and Socioemotional Competence: Interacting Risk Factors in the Development of Childhood Conduct Disorder Symptoms. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 52(7), 718 - 727. doi:10.1016/j..jaac.2013.04.011
    • Mandy W, Roughan L, Skuse D (2013). Three Dimensions of Oppositionality in Autism Spectrum Disorder.. J Abnorm Child Psychol, , - . doi:10.1007/s10802-013-9778-0
    • Smith-Collins AP, Fiorentini C, Kessler E, Boyd H, Roberts F, Skuse DH (2013). Specific neural correlates of successful learning and adaptation during social exchanges.. Soc Cogn Affect Neurosci, 8(8), 887 - 896. doi:10.1093/scan/nss079
    • Arkush L, Smith-Collins APR, Fiorentini C, Skuse DH (2013). Recognition of Face and Non-Face Stimuli in Autistic Spectrum Disorder. AUTISM RESEARCH, 6(6), 550 - 560. doi:10.1002/aur.1318
    • Kothari R, Skuse D, Wakefield J, Micali N (2013). Gender Differences in the Relationship Between Social Communication and Emotion Recognition. Journal of the American Academy of Child & Adolescent Psychiatry, 52(11), 1148 - 1157.e2. doi:10.1016/j.jaac.2013.08.006
    • Mandy W, Charman T, Puura K, Skuse D (2013). Investigating the cross-cultural validity of DSM-5 autism spectrum disorder: Evidence from Finnish and UK samples.. Autism, , - . doi:10.1177/1362361313508026

    2012

    • Ricotti V, Scoto M, Mandy WPL, Entwistle K, Robb SA, Mercuri E, Skuse DH, Muntoni F (2012). Neurobehavioural disorders in Duchenne Muscular Dystrophy. doi:10.1016/j.nmd.2012.06.278
    • Mandy WP, Skuse DH, Charman T, Frazier TW (2012). In defense of lumping (and splitting).. J Am Acad Child Adolesc Psychiatry, 51(4), 441 - 442. doi:10.1016/j.jaac.2012.02.004
    • Sadiq FA, Slator L, Skuse D, Law J, Gillberg C, Minnis H (2012). Social use of language in children with reactive attachment disorder and autism spectrum disorders. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 21(5), 267 - 276. doi:10.1007/s00787-012-0259-8
    • Leblond CS, Heinrich J, Delorme R, Proepper C, Betancur C, Huguet G, Konyukh M, Chaste P, Ey E, Rastam M, Anckarsater H, Nygren G, Gillberg IC, Melke J, Toro R, Regnault B, Fauchereau F, Mercati O, Lemiere N, Skuse D, Poot M, Holt R, Monaco AP, Jarvela I, Kantojarvi K, Vanhala R, Curran S, Collier DA, Bolton P, Chiocchetti A, Klauck SM, Poustka F, Freitag CM, Waltes R, Kopp M, Duketis E, Bacchelli E, Minopoli F, Ruta L, Battaglia A, Mazzone L, Maestrini E, Sequeira AF, Oliveira B, Vicente A, Oliveira G, Pinto D, Scherer SW, Zelenika D, Delepine M, Lathrop M, Bonneau D, Guinchat V, Devillard F, Assouline B, Mouren M-C, Leboyer M, Gillberg C, Boeckers TM, Bourgeron T (2012). Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders. PLOS GENETICS, 8(2), - . doi:10.1371/journal.pgen.1002521
    • Briscoe J, Chilvers R, Baldeweg T, Skuse D (2012). A specific cognitive deficit within semantic cognition across a multi-generational family.. Proc Biol Sci, 279(1743), 3652 - 3661. doi:10.1098/rspb.2012.0894
    • Garcia-Hernandez J, Mohmaduvesh M, Davies P, Quaglia E, Toumpanakis C, Skuse DH, Caplin M (2012). Depression and Carcinoid Syndrome: Is There Any Relationship? A Cross-Sectional Study.
    • Mandy WP, Charman T, Skuse DH (2012). Testing the construct validity of proposed criteria for DSM-5 autism spectrum disorder.. J Am Acad Child Adolesc Psychiatry, 51(1), 41 - 50. doi:10.1016/j.jaac.2011.10.013
    • Skuse DH (2012). DSM-5's conceptualization of autistic disorders.. J Am Acad Child Adolesc Psychiatry, 51(4), 344 - 346. doi:10.1016/j.jaac.2012.02.009
    • Ricotti V, Mandy WPL, Robb SA, Skuse DH, Muntoni F (2012). Neurobehavioural disorders in Duchenne Muscular dystrophy.
    • Skuse DH (2012). Learning from chromosomal disorders: progress and prospects.. Curr Opin Neurol, 25(2), 103 - 105. doi:10.1097/WCO.0b013e3283519a3b
    • Mandy W, Chilvers R, Chowdhury U, Salter G, Seigal A, Skuse D (2012). Sex differences in autism spectrum disorder: evidence from a large sample of children and adolescents.. J Autism Dev Disord, 42(7), 1304 - 1313. doi:10.1007/s10803-011-1356-0

    2011

    • Curran S, Bolton P, Rozsynai K, Chicchetti A, Klauk SM, Ducetis E, Poustka F, Schlitt S, Freitag C, Lee I, Muglia P, Poot M, Staal W, de Jonge M, Ophoff R, Lewis C, Skuse D, Mandy W, Vassos E, Fossdal R, Magnusson P, Hreidarsson S, Saemundsen E, Stefansson H, Stefansson K, Collier D (2011). No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and Autism Spectrum Disorder. American Journal of Medical Genetics - B Neuropsychiatric Genetics, 156B(6), 633 - 699. doi:10.1002/ajmg.b.31201
    • Baker K, Baldeweg T, Chaddock C, Skuse D (2011). 22q11 deletion syndrome - understanding neurodevelopmental disorders in a common CNV.
    • Skuse D (2011). Genetics of Autistic Disorders.
    • Baker K, Chaddock CA, Baldeweg T, Skuse D (2011). Neuroanatomy in adolescents and young adults with 22q11 deletion syndrome: comparison to an IQ-matched group.. Neuroimage, 55(2), 491 - 499. doi:10.1016/j.neuroimage.2010.12.041
    • Skuse DH, Gallagher L (2011). Genetic influences on social cognition.. Pediatr Res, 69(5 Pt 2), 85R - 91R. doi:10.1203/PDR.0b013e318212f562
    • St Pourcain B, Mandy WP, Heron J, Golding J, Davey Smith G, Skuse DH (2011). Links between co-occurring social-communication and hyperactive-inattentive trait trajectories.. J Am Acad Child Adolesc Psychiatry, 50(9), 892 - 902.e5. doi:10.1016/j.jaac.2011.05.015
    • Oliver BR, Barker ED, Mandy WP, Skuse DH, Maughan B (2011). Social cognition and conduct problems: a developmental approach.. J Am Acad Child Adolesc Psychiatry, 50(4), 385 - 394. doi:10.1016/j.jaac.2011.01.006
    • Skuse D, Bruce H, Dowdney L, Mrazek D (2011). Child Psychology and Psychiatry.
    • Lester BM, Tronick E, Nestler E, Abel T, Kosofsky B, Kuzawa CW, Marsit CJ, Maze I, Meaney MJ, Monteggia LM, Reul JM, Skuse DH, Sweatt JD, Wood MA (2011). Behavioral epigenetics.. Ann N Y Acad Sci, 1226, 14 - 33. doi:10.1111/j.1749-6632.2011.06037.x
    • Mandy W, Charman T, Gilmour J, Skuse D (2011). Toward specifying pervasive developmental disorder-not otherwise specified.. Autism Res, 4(2), 121 - 131. doi:10.1002/aur.178

    2009

    • Skuse DH, Mandy WPL, Steer C, Miller LL, Goodman R, Lawrence K, Emond A, Golding J (2009). Social Communication Competence and Functional Adaptation in a General Population of Children: Preliminary Evidence for Sex-by-Verbal IQ Differential Risk. Journal of the American Academy of Child and Adolescent Psychiatry, 48(2), 128 - 137. doi:10.1097/CHI.0b013e31819176b8
    • Skuse DH (2009). Is autism really a coherent syndrome in boys, or girls?. British Journal of Psychology, 100, 33 - 37.
    • Skuse DH, Gallagher L (2009). Dopaminergic-neuropeptide interactions in the social brain.. Trends Cogn Sci, 13(1), 27 - 35. doi:10.1016/j.tics.2008.09.007
    • McCarthy SE, Makarov V, Kirov G, Addington AM, McClellan J, Yoon S, Perkins DO, Dickel DE, Kusenda M, Krastoshevsky O, Krause V, Kumar RA, Grozeva D, Malhotra D, Walsh T, Zackai EH, Kaplan P, Ganesh J, Krantz ID, Spinner NB, Roccanova P, Bhandari A, Pavon K, Lakshmi B, Leotta A, Kendall J, Lee YH, Vacic V, Gary S, Iakoucheva LM, Crow TJ, Christian SL, Lieberman JA, Stroup TS, Lehtimaki T, Puura K, Haldeman-Englert C, Pearl J, Goodell M, Willour VL, DeRosse P, Steele J, Kassem L, Wolff J, Chitkara N, McMahon FJ, Malhotra AK, Potash JB, Schulze TG, Nothen MM, Cichon S, Rietschel M, Leibenluft E, Kustanovich V, Lajonchere CM, Sutcliffe JS, Skuse D, Gill M, Gallagher L, Mendell NR, Craddock N, Owen MJ, O'Donovan MC, Shaikh TH, Susser E, DeLisi LE, Sullivan PF, Deutsch CK, Rapoport J, Levy DL, King MC, Sebat J, Wellcome Trust Case Control Consor (2009). Microduplications of 16p11.2 are associated with schizophrenia. NAT GENET, 41(11), 1223 - U85. doi:10.1038/ng.474

    2008

    • McMillan D, Hastings RP, Salter DC, Skuse DH (2008). Developmental risk factor research and sexual offending against children: a review of some methodological issues.. Arch Sex Behav, 37(6), 877 - 890. doi:10.1007/s10508-007-9193-0
    • Boraston ZL, Corden B, Miles LK, Skuse DH, Blakemore SJ (2008). Brief report: perception of genuine and posed smiles by individuals with autism.. J Autism Dev Disord, 38(3), 574 - 580. doi:10.1007/s10803-007-0421-1
    • Salter G, Seigal A, Claxton M, Lawrence K, Skuse D (2008). Can autistic children read the mind of an animated triangle?. Autism, 12(4), 349 - 371.
    • Lawrence K, Bernstein D, Pearson R, Mandy W, Campbell R, Skuse D (2008). Changing abilities in recognition of unfamiliar face photographs through childhood and adolescence: Performance on a test of non-verbal immediate memory (Warrington RMF) from 6 to 16 years. Journal of Neuropsychology, 2, 27 - 45.
    • Boraston Z, David Skuse D, Blakemore SJ (2008). Perception of genuine and posed smiles by individuals with autism.. Journal of Autism and Developmental Disorders, , - .
    • Mandy WPL, Skuse DH (2008). Research Review: What is the association between the social-communication element of autism and repetitive interests, behaviours and activities?. Journal of Child Psychology and Psychiatry, 49(8), 795 - 808.
    • Corden B, Chilvers R, Skuse D (2008). Avoidance of emotionally arousing stimuli predicts social-perceptual impairment in Asperger's syndrome. NEUROPSYCHOLOGIA, 46(1), 137 - 147. doi:10.1016/j.neuropsychologia.2007.08.005
    • Corden B, Chilvers R, Skuse D (2008). Emotional modulation of perception in Asperger's syndrome. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 38(6), 1072 - 1080. doi:10.1007/s10803-007-0485-y
    • Lawrence K, Bernstein D, Pearson R, Mandy W, Campbell R, Skuse DH (2008). Changing abilities in recognition of unfamiliar face photographs through childhood and adolescence: Performance on a test of nonverbal immediate memory (Warrington RMF) from six to sixteen years. Journal of Neuropsychology, 2(1), 27 - 45. doi:10.1348/174866407X231074

    2007

    • Lawrence K, Jones A, Oreland L, Spektor D, Mandy W, Campbell R, Skuse D (2007). The development of mental state attributions in women with X-monosomy, and the role of monoamine oxidase B in the sociocognitive phenotype. COGNITION, 102(1), 84 - 100. doi:10.1016/j.cognition.2005.12.003
    • Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimaki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M (2007). Strong association of de novo copy number mutations with autism. Science, 316(5823), 445 - 449.
    • Boraston Z, Blakemore SJ, Chilvers R, Skuse D (2007). Impaired sadness recognition is linked to social interaction deficit in autism. Neuropsychologia, 45(7), 1501 - 1510.
    • Lawrence K, Jones A, Oreland L, Spektor D, Mandy W, Campbell R, Skuse DH (2007). The development of mental state attributions in women with X-monosomy, and the role of monamine-oxidase B in the sociocognitive phenotype. Cognition, 102(1), 84 - 100. doi:10.1016/j.cognition.2005.12.003
    • Weiss LA, Purcell S, Waggoner S, Lawrence K, Spektor D, Daly MJ, Sklar P, Skuse D (2007). Identification of EFHC2 as a quantitative trait locus for fear recognition in Turner syndrome. Human Molecular Genetics, 16(1), 107 - 113. doi:10.1093/hmg/ddl445
    • Skuse D (2007). Rethinking the nature of genetic vulnerability to autism spectrum disorders. Trends in Genetics, 23(8), 387 - 395.
    • Sivagnanasundaram S, Fletcher D, Hubank M, Illingworth E, Skuse D, Scambler P (2007). Differential gene expression in the hippocampus of the Df1/+ mice: A model for 22q11.2 deletion syndrome and schizophrenia. Brain Research, 1139, 48 - 59.

    2006

    • Corden B, Critchley HD, Skuse D, Dolan RJ (2006). Fear recognition ability predicts differences in social cognitive and neural functioning in men. Journal of Cognitive Neuroscience, 18(6), pp.889 - 897.
    • Skuse D, Chilvers R, The Media Trust JMA (2006). The Hidden Face of Autism.
    • Mazzola F, Seigal A, MacAskill A, Corden B, Lawrence K, Skuse DH (2006). Eye tracking and fear recognition deficits in Turner syndrome. Social Neuroscience, 1(3-4), 259 - 269.
    • Skuse D (2006). Genetic influences on the neural basis of social cognition. Philosophical Transactions of the Royal Society B: Biological Sciences, 361(1476), 2129 - 2141.
    • Skuse DH (2006). Sexual dimorphism in cognition and behaviour: the role of X-linked genes. European Journal of Endocrinology, 155, S99 - S106.
    • Campbell R, Lawrence K, Mandy W, Mitra C, Jeyakuma L, Skuse D (2006). Meanings in motion and faces: Developmental associations between the processing of intention from geometrical animations and gaze detection accuracy. Development and Psychopathology, 18(1), 99 - 118. doi:10.1017/S0954579406060068
    • Chaddock C, Lee L, Newton J, Baldeweg T, Frackowiak R, Skuse D (2006). A combined VBM and DTI investigation of brain structure in 22Q11 deletion syndrome: Investigations of structure-function relationships. Schizophrenia Research, 81, 155 - 156.
    • Marco EJ, Skuse DH (2006). Autism-lessons from the X chromosome. Social Cognitive and Affective Neuroscience, 1, 183 - 193.
    • Skuse DH, Baker K (2006). Brain: Neurodevelopmental Genetics. In (Ed.), Encyclopaedia of Life Sciences (pp. - ). : John Wiley & Sons Ltd.. doi:10.1038/npg.els.0005145
    • Wade AM, Lawrence K, Mandy W, Skuse D (2006). Charting the development of emotion recognition from 6 years of age. Journal of Applied Statistics, 33(3), 297 - 315.
    • Cutter WJ, Daly EM, Robertson DMW, Chitnis XA, van Amelsvoort TAMJ, Simmons A, Ng VWK, Williams BS, Shaw P, Conway GS, Skuse DH, Collier DA, Craig M, Murphy DGM (2006). Influence of X chromosome and hormones on human brain development: A magnetic resonance imaging and proton magnetic resonance spectroscopy study of Turner syndrome. Biological Psychiatry, 59(3), 273 - 283.
    • Wolke DW, Skuse DH, Reilly S (2006). Management of infant feeding problems. In Cooper PJ, Stein A (Ed.), Childhood feeding problems and adolescent eating disorders (pp. 41 - 91). : Routledge.
    • Reilly S, Skuse DH, Wolke DW (2006). Nature of feeding problems in infants. In Cooper PJ, Stein A (Ed.), Childhood feeding problems and adolescent eating disorders (pp. 7 - 40). : Routledge.
    • Skuse DH, Warrington R (2006). The Developmental, Dimensional and Diagnostic Interview (for autistic children).
    • Corden B, Critchley HD, Skuse D, Dolan RJ (2006). Fear recognition ability predicts differences in social cognitive and neural functioning in men.. J Cogn Neurosci, 18(6), 889 - 897. doi:10.1162/jocn.2006.18.6.889

    2005

    • Skuse DH, Lawrence K (2005). Behavioural Phenotypes.. Psychiatry, 4, 65 - 68.
    • Baker K, Baldeweg T, Sivagnanasundaram S, Scambler P, Skuse D (2005). COMT Val(108/158)Met modifies mismatch negativity and cognitive function in 22q11 deletion syndrome. Biological Psychiatry, 58(1), 23 - 31. doi:10.1016/j.biopsych.2005.03.020
    • Skuse DH, Morris JS, Dolan RJ (2005). Functional dissociation of amygdala-modulated arousal and cognitive appraisal, in Turner syndrome. Brain, 128(9), 2084 - 2096. doi:10.1093/brain/awh562
    • Skuse DH, Mandy WP, Scourfield J (2005). Measuring autistic traits: heritability, reliability and validity of the Social and Communication Disorders Checklist. The British Journal of Psychiatry, 187(6), 568 - 572. doi:10.1192/bjp.187.6.568
    • Davies W, Isles A, Smith R, Karunadasa D, Burrmann D, Humby T, Ojarikre O, Biggin C, Skuse D, Burgoyne P, Wilkinson L (2005). Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice. Nature Genetics, 37(6), 625 - 629.
    • Khera N, Davies H, Davies H, Lissauer T, Skuse D, Wakeford R, Stroobant J (2005). How should paediatric examiners be trained?. Archives of Disease in Childhood, 90(1), 43 - 47.
    • Skuse D, Lawrence K, Tang J (2005). Measuring social-cognitive functions in children with somatotropic axis dysfunction. Hormone Research, 64 Suppl 3, 73 - 82.
    • Corden B, Skuse DH (2005). The perception of emotionally salient events in Asperger syndrome - Evidence for amygdala dysfuntion. Journal of Cognitive Neuroscience, Suppl. 117, - .
    • Skuse DH (2005). X-linked genes and mental functioning. Human Molecular Genetics, 14, R27 - R32.
    • Baker KD, Skuse DH (2005). Adolescents and young adults with 22q11 deletion syndrome: psychopathology in an at-risk group. The British Journal of Psychiatry, 186(2), 115 - 120.

    2004

    • Baker K, Baldeweg I, Siva S, Scambler P, Skuse D (2004). Mismatch negativity in 22q11 deletion syndrome - Evidence for psychosis-like developmental disruption.
    • Skuse DH, Purcell S, Daly MJ, Dolan RJ, Morris JS, Lawrence K, Lander ES, Sklar P (2004). What can studies on Turner syndrome tell us about the role of X-linked genes in social cognition?. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 130B(1), 8 - 9.
    • Gilmour J, Hill B, Place M, Skuse DH (2004). Social communication deficits in conduct disorder: a clinical and community survey. Journal of Child Psychology and Psychiatry, 45(5), 967 - 978.
    • Skuse D (2004). Genetics and genomics of neurobehavioral disorders. Journal of Child Psychology and Psychiatry, 45(6), 1180 - 1181.
    • Baker K, Baldeweg I, Siva S, Scambler P, Skuse DH (2004). Mismatch negativity in 22q11 deletion syndrome - Evidence for psychosis-like developmental disruption. Schizophrenia Research, 67(1 Suppl. S), 23 - .
    • Skuse D, Warrington R, Bishop D, Chowdhury U, Lau J, Mandy W, Place M (2004). The developmental, dimensional and diagnostic interview (3di): A novel computerized assessment for autism spectrum disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 43(5), 548 - 558.

    2003

    • Good CD, Lawrence K, Thomas NS, Price CJ, Ashburner J, Friston KJ, Frackowiak RSJ, Oreland L, Skuse DH (2003). Dosage-sensitive X-linked locus influences the development of amygdala and orbitofrontal cortex, and fear recognition in humans. Brain, 126(11), 2431 - 2446. doi:10.1093/brain/awg242
    • Lawrence K, Kuntsi J, Coleman M, Campbell R, Skuse D (2003). Face and emotion recognition deficits in Turner syndrome: a possible role for X-linked genes in amygdala development. Neuropsychology, 17(1), 38 - 49. doi:10.1037/0894-4105.17.1.39
    • Skuse D, Morris J, Lawrence K (2003). The amygdala and the development of the social brain. Annals of the New York Academy of Sciences, 1008, 91 - 101.
    • Baker KD, Baldeweg T, Scambler P, Skuse DH (2003). 22q11 deletion syndrome: A search for clues to the origins of schizophrenia. Journal of Neurology, Neurosurgery and Psychiatry, 74(6), 834 - .
    • Skuse DH (2003). Child Psychology and Psychiatry: An Introduction.
    • Salter D, McMillan D, Richards M, Talbot T, Hodges J, Bentovim A, Hastings R, Stevenson J, Skuse D (2003). Development of sexually abusive behaviour in sexually victimised males: a longitudinal study. The Lancet, 361(9356), 471 - 476. doi:10.1016/S0140-6736(03)12466-X
    • Skuse DH (2003). Fear recognition and the neural basis of social cognition. Child and Adolescent Mental Health, 8(2), 50 - 60.
    • Morris J, Skuse DH, Dolan RJ (2003). Fear, amygdala and the X chromosome. European Neuropsychopharmacology, Suppl.4, S124 - S125.
    • Skuse DH, Baker KD (2003). Genes and behaviour: finding a genetic substrate for cognitive neuropsychiatry. In Ron MA, Robbins TW, David AS (Ed.), (pp. - ). : .
    • Lawrence K, Campbell R, Swettenham J, Terstegge J, Akers R, Coleman M, Skuse D (2003). Interpreting gaze in Turner syndrome: impaired sensitivity to intention and emotion, but preservation of social cueing. Neuropsychologia, 41(8), 894 - 905. doi:10.1016/S0028-3932(03)00002-2
    • Skuse DH, Baker K (2003). Neurodevelopmental Genetics of Brain. In Cooper DN (Ed.), Encyclopedia of the human genome (pp. - ). : Nature Publishing Group.
    • Fonagy P (2003). Psychosocial therapies for young people: Individual approaches. In Skuse DH (Ed.), Child Psychology and Psychiatry (pp. 161 - 164). : The Medicine Publishing Company.
    • Skuse DH (2003). X-linked genes and the neural basis of social cognition. Autism: Neural Basis and Treatment Possibilities Novartis Foundation Symposium, 251, 84 - 111.

    2002

    • Elgar K, Campbell R, Skuse D (2002). Are you looking at me? Accuracy in processing line-of-sight in Turner syndrome. Proceedings of the Royal Society B: Biological Sciences, 269(1508), 2415 - 2422.
    • Elgar K, Campbell R, Terstegge J, Akers R, Coleman M, Skuse DH (2002). Impaired processing of direction of gaze in Turner syndrome - Evidence for amygdala dysfunction. Journal of Cognitive Neuroscience, Suppl. S21(21), - .
    • Skuse DH, Kuntsi J (2002). Chromosomal anomalies: cognitive and behavioural consequences. In Rutter M, Taylor E (Ed.), Child and Adolescent Psychiatry (pp. 205 - 240). : Blackwell Scientific Publications.
    • (2002). Behavioural phenotypes and chromosomal disorders. Psychiatry, 1, 98 - 101.
    • Campbell R, Elgar K, Kuntsi J, Akers R, Terstegge J, Coleman M, Skuse D (2002). The classification of 'fear' from faces is associated with face recognition skill in women.. Neuropsychologia, 40(6), 575 - 584. doi:10.1016/S0028-3932(01)00164-6
    • Campbell R, Elgar K, Kuntsi J, Coleman M, Terstegge J, Akers R, Skuse D (2002). The categorisation of fear in faces is associated with face recognition in women. Neuropsychologia, 40(6), 575 - 584.

    2001

    • Skuse DH, Warrington RH (2001). Computer based interviewing system.
    • (2001). Effects of dosage insufficiency of X linked genes on brain structures and visual processing style. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 71(1), 140 - 140.
    • (2001). Endophenotypes and child psychiatry. The British Journal of Psychiatry, 178, 395 - 396.
    • Good CD, Kuntsi J, Akers R, Elgar K, Price C, Ashburner J, Friston KJ, Frackowiak RSJ, Skuse DH (2001). Gene deletion mapping of the X chromosome. NeuroImage, 13(6), S793 - S793.
    • (2001). Hyperphagic short stature and Prader-Willi syndrome: a comparison of behavioural phenotypes, genotypes and indices of stress. The British Journal of Psychiatry, 179, 129 - 137.
    • (2001). Individual differences in the cognitive planning on the Tower of Hanoi task: Neuropsycgological maturity or measurement error?. Journal of Child Psychology and Psychiatry, 42, 551 - 556.

    2000

    • Kuntsi J, Skuse DH, Elgar K, Morris E, Turner C (2000). Ring-X chromosomes: their cognitive and behavioural phenotype. Annals of Human Genetics, 64(4), 295 - 305.
    • Turner C, Dennis NR, Skuse DH, Jacobs PA (2000). Seven ring (X) chromosomes lacking the XIST locus, six with an unexpectedly mild phenotype. Human Genetics, 106, 93 - 100.
    • Dennis N, Coppin B, Turner C, Skuse DH, Jacobs P (2000). A clinical, cytogenetic and molecular study of 47 females with r(X) chromosomes. Annals of Human Genetics, 64(4), 277 - 293.
    • Skuse DH (2000). Behavioural neuroscience and child psychopathology: Insights from model systems. Journal of Child Psychology and Psychiatry, 41(1), 3 - 31.
    • Skuse DH (2000). Behavioural phenotypes: what do they teach us?. Archives of Disease in Childhood, 82, 222 - 225.
    • Skuse DH, Kuntsi J (2000). Chromosomal disorders. In Rutter M, Taylor E (Ed.), Child and adolescent psychiatry (pp. - ). : Blackwell.
    • Bishop C, E E, K M, E J, P S, D H (2000). Distinctive patterns of memory in subgroups of females with Turner syndrome: evidence for imprinted loci on the X-chromosome affecting neurodevelopment. Neuropsychologia, 38, 712 - 721.
    • Skuse DH (2000). Genetic anomalies: their cognitive and behavioural consequences. In Rutter M, Taylor E (Ed.), Child and adolescent psychiatry (pp. - ). : Blackwell.
    • Kuntsi J, Skuse D, Elgar K, Morris E, Turner C (2000). Ring-X chromosomes: their cognitive and behavioural phenotype.. Ann Hum Genet, 64(Pt 4), 295 - 305. doi:10.1017/S0003480000008174
    • Good CD, Kuntsi J, Shah B, Price CJ, Ashburner J, Friston KJ, Frackowiak RS, Skuse DH (2000). Voxel based morphometry in deletion mapping studies of the X chromosome. European Journal of Neuroscience, 12, 164 - 164.
    • Petronis A, Gottesman I, Crow TJ, DeLisi LE, Klar AJ, Macciardi F, McInnis MG, McMahon FJ, Paterson AD, Skuse DH, Sutherland GR (2000). Psychiatric epigenetics: a new focus for the new century. Molecular Psychiatry, 5(4), 342 - 346.
    • Skuse D, Bishop D, Elgar K, Morris E (2000). Phenotype-karyotype relationships in Turner syndrome. In Stabler B, Bercu BB (Ed.), Therapeutic outcome of endocrine disorders (pp. 69 - 82). : Norwell,MA.
    • Boddy J, Skuse DH, Andrews B (2000). The developmental sequelae of nonorganic failure to thrive. Journal of Child Psychology and Psychiatry, 41(8), 1003 - 1014.
    • Skuse DH (2000). Imprinting, the X-chromosome, and the male brain: Explaining sex differences in the liability to autism. Pediatric Research, 47(1), 9 - 16.

    1999

    • Creswell CS, Skuse DH (1999). Autism in association with Turner syndrome: genetic implications for male vulnerability to pervasive developmental disorders. Neurocase, 5, 101 - 108.
    • Skuse DH (1999). Genomic imprinting of the X chromosome: A novel mechanism for the evolution of sexual dimorphism. The Journal of Laboratory and Clinical Medicine, 133(10), 23 - 32.
    • Butterworth B, Grana A, Piazza M, Girelli L, Price C, Skuse D (1999). Language and the origins of number skills: Karyotypic differences in Turner's Syndrome. Brain and Language, 69(3), pp.486 - 488.
    • Reilly SM, Skuse DH, Wolke D, Stevenson J (1999). Oral-motor dysfunction in children who fail to thrive: organic or non-organic?. Developmental Medicine and Child Neurology, 41, 115 - 122.
    • Dowdney L, Wilson R, Maughan B, Allerton M, Schofield P, Skuse D (1999). Psychological disturbance and service provision in parentally bereaved children: prospective case-control study. BMJ (Clinical Research Ed.), 319, 354 - 357.
    • Skuse DH, Elgar K, Morris E (1999). Quality of life in Turner syndrome is related to chromosomal constitution: implications for genetic counselling and management. Acta Paediatrica, Suppl.428, 110 - 113.
    • Skuse DH (1999). Survival after being born too soon, but at what cost?. The Lancet, 354(9176), 354 - 355.
    • Skuse DH, Price CJ, Jacobs PA, Bishop DVM (1999). X-chromosome imprinting and its potential influence upon sexual dimorphism in neurodevelopmental disorders: New evidence from structural brain imaging. Molecular Psychiatry, 4(Suppl. 1), S18 - .
    • Thomas NS, Sharp AJ, Browne CE, Skuse DH, Hardie C, Dennis NR (1999). Xp deletions associated with autism in three females. Human Genetics, 104(1), 43 - 48.
    • Creswell CS, Skuse DH (1999). Autism in association with Turner syndrome: Genetic implications for male vulnerability to pervasive developmental disorders. NEUROCASE, 5(6), 511 - 518.
    • New M, Stevenson J, Skuse D (1999). Child maltreatment. Journal of the American Professional Society on the Abuse of Children, 4, 21 - 31.
    • Gilmour J, Skuse D (1999). A case-comparison study of the characteristics of children with a short stature syndrome induced by stress (Hyperphagic Short Stature) and a consecutive series of unaffected "stressed" children. Journal of Child Psychology and Psychiatry, 40, 969 - 978.
    • Robinson DO, Dalton P, Jacobs PA, Mosse K, Power MM, Skuse DH, Crolla JA (1999). A molecular and FISH analysis of structurally abnormal Y chromosomes in patients with Turner syndrome. Journal of Medical Genetics, 36(4), 279 - 284.

    1998

    • James RS, Coppin B, Dalton P, Dennis NR, Mitchell C, Sharp AJ, Skuse DH, Thomas NS, Jacobs PA (1998). A study of females with deletions of the short arm of the X chromosome. Human Genetics, 102(5), 507 - 516.
    • Skuse DH (1998). Environmental disadvantage: A longitudinal study of growth and cognitive development from 4 to 11 years. Journal of Child Psychology and Psychiatry, 39(7), 1017 - 1029.
    • Skuse DH, R S B, D V M J, P A (1998). Evidence from Turner syndrome of an imprinted X-linked locus affecting cognitive function. European Journal of Neuroscience, (10), 330 - .
    • Khadilkar VV, Frazer FL, Skuse DH, Stanhope R (1998). Metaphyseal growth arrest lines in psychosocial short stature. Archives of Disease in Childhood, 79(3), 260 - 262.
    • Skuse DH (1998). Psychiatric aspects of chromosomal microdeletions and trinucleotide repeats. Current Opinion in Psychiatry, 11(4), 373 - 378.
    • Dalton P, Coppin B, James R, Skuse D, Jacobs P (1998). Three patients with a 45,X/46,X,psu dic(Xp)karyotype. Journal of Medical Genetics, 35(6), 519 - 524.
    • Skuse DH, Cave S, O'Herlihy A, South R (1998). Quality of life in children with Turner syndrome: Parent, teacher, and individual perspectives.
    • Skuse DH, Gilmour J (1998). Psychological disorders. In Kelnar CJH, Savage MO, Stirling HF, Saenger P (Ed.), Growth Disorders: Pathophysiology and Treatment (pp. 483 - 496). : Chapman & Hall, London.
    • Skuse DH, Bentovim A, Hodges J, Stevenson J, Andreou C, Lanyado M, New M, Williams B, McMillan D (1998). Risk factors for development of sexually abusive behaviour in sexually victimised adolescent boys: cross sectional study.. BMJ (Clinical Research Ed.), 317(7152), 175 - 179.
    • Dowdney L, Skuse DH, Morris K, Pickles A (1998). Short normal children and environmental disadvantage: A longitudinal study of growth and cognitive development from 4 to 11 years. Journal of Child Psychology and Psychiatry, 39(7), 1017 - 1029.
    • Skuse DH (1998). The two sexes: Growing up apart, coming together.. Nature, 393(6681), 131 - 132.
    • Gohlke BC, Khadilkar VV, Skuse DH, Stanhope R (1998). Recognition of children with psychosocial short stature: A spectrum of presentation. Journal of Pediatric Endocrinology and Metabolism, 11(4), 509 - 517.

    1997

    • Skuse D (1997). Emotional abuse and neglect. In Meadow R (Ed.), ABC of child abuse (pp. 30 - 33). : BMJ Publishing Group.
    • Skuse D, Gilmour J (1997). Abuse and short stature. In Meadow R (Ed.), ABC of child abuse (pp. 34 - 37). : BMJ Publishing Group.
    • Skuse DH (1997). Castlemead Growth Program II. ARCH DIS CHILD, 76(4), 392 - 392.
    • Skuse D, Jacobs P (1997). Mosaicism in Turner's syndrome - Reply. NATURE, 390(6660), 569 - 569. doi:10.1038/37516
    • Skuse DJ, James RS, Bishop C, B D, P A-L, G B-H, M C, C M, R J, P A (1997). Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function. Nature, 387, 705 - 708.
    • Jacobs P, Dalton P, James R, Mosse K, Power M, Robinson D, Skuse DH (1997). Turner Syndrome: a cytogenetic and molecular study. Annals of Human Genetics, 61(6), 471 - 483.
    • Skuse DH (1997). Psychosocial disorders in young people: Time trends and their causes - Review of: Rutter, M., Smith, D.J.. Child: Care, Health and Development, 23(4), 360 - 361.
    • Skuse D (1997). Genetic factors in the aetiology of child psychiatric disorders. Current Opinion in Pediatrics, 9, 354 - 360.
    • Skuse DH, Jacobs P (1997). Mosaicism in Turner's syndrome - Reply. Nature, 390(660), 569 - .

    1996

    • Gilmour J, Skuse , D H (1996). Short stature - The role of intelligence in psychosocial adjustment.. Archives of Disease in Childhood, 75(1), 25 - 31.
    • Gilmour J, Skuse DH (1996). Hyperphagic short stature: A genetic syndrome?. Behavior Genetics, 26(6), 585 - 586.
    • Skuse DH, Albanses A, Stanhope R, Gilmour J, Voss L (1996). A new stress-related syndrome of growth failure and hyperphagia in children, associated with reversibility of growth-hormone insufficiency.. The Lancet, 348(9024), 353 - 358.
    • Skuse DH, Gilmour J, Stanhope R, Albanese A, Voss L (1996). Stress-related growth failure - Reply. LANCET, 348(9034), 1104 - 1105.
    • Skuse DH, Gilmour J, Stanhope R, Albanese A, Voss L (1996). Stress-related growth failure. The Lancet, 348(9034), 1104 - 1105.

    1995

    • Reilly S, Skuse DH, Mathisen B, Wolke D (1995). The Objective Rating of Oral Motor Functions During Feeding. Dysphagia, 10(3), 177 - 191.
    • Skuse DH, Stevenson J, Reilly S, Mathisen B (1995). Schedule for Oral-Motor Assessment (SOMA) Methods of Validation. Dysphagia, 10(3), 192 - 202.
    • Ratip S, Skuse D, Porter J, Wonke B, Yardumian A, Modell B (1995). Psychosocial and clinical burden of thalassaemia intermedia and its implications for prenatal diagnosis.. Arch Dis Child, 72(5), 408 - 412.
    • Skuse DH (1995). Motherhood in Human and Nonhuman Primates: Biosocial Determinants.
    • Dowdney L, Woodward L, Pickles A, Skuse DH (1995). The Body Image Perception and Attitude Scale for Children-Reliability in Growth Retarded and Community Comparison Subjects. International Journal of Methods in Psychiatric Research, 5(1), 29 - 40.
    • Puckering C, Pickles A, Skuse DH, Heptinstall E, Dowdney L, Zurszpiro S (1995). Mother-Child Interaction and the Cognitive and Behavioural Development of 4 year old Children with Poor Growth. Journal of Child Psychology and Psychiatry, 36(4), 573 - 595.
    • Skuse DH, Gill D, Reilly S, Wolke D, Lynch MA (1995). Failure to thrive and the risk of child abuse: a prospective population survey.. J Med Screen, 2(3), 145 - 149.
    • Ratip S, Skuse DH, Porter , J , Wonke , B , Yardumian , A , Modell , B (1995). Psychosocial and Clinical Burden of Thalassemia-Intermedia and its Implications for Prenatal-Diagnosis. Archives of Disease in Childhood, 72(5), 408 - 412.

    1994

    • SKUSE D, GILMOUR J, TIAN C, HINDMARSH P (1994). PSYCHOSOCIAL ASSESSMENT OF CHILDREN WITH SHORT STATURE - A PRELIMINARY-REPORT. doi:10.1111/j.1651-2227.1994.tb13413.x
    • BODDY JM, SKUSE DH (1994). ANNOTATION - THE PROCESS OF PARENTING IN FAILURE-TO-THRIVE. J CHILD PSYCHOL PSYC, 35(3), 401 - 424.
    • Boddy JM, Skuse DH (1994). The process of parenting in failure to thrive.. J Child Psychol Psychiatry, 35(3), 401 - 424.
    • SKUSE DH, WOLKE DF, REILLY S (1994). Socio-economic disadvantage and ethnic influences upon infant growth in inner London.

    1990

    • SKUSE DH (1990). NUTRITIONAL EFFECTS ON MENTAL-DEVELOPMENT AND PERFORMANCE - A REAL PROBLEM.

    1989

    • Skuse DH (1989). ABC of child abuse. Emotional abuse and delay in growth.. BMJ, 299(6691), 113 - 115.
    • Skuse DH (1989). ABC of child abuse. Emotional abuse and neglect.. BMJ, 298(6689), 1692 - 1694.

    1987

    • Skuse DH (1987). Child sex abuse in general practice: recognition and response.. Practitioner, 231(1429), 706 - 711.

    1985

    • SKUSE DH (1985). GLUE SNIFFING AND VOLATILE SUBSTANCE ABUSE - OCONNOR,D. BEHAV PSYCHOTHER, 13(3), 262 - 263.
    • Skuse DH (1985). Non-organic failure to thrive: a reappraisal.. Arch Dis Child, 60(2), 173 - 178.

    1984

    • SKUSE DH (1984). THE BEHAVIOR OF HUMAN INFANTS - OLIVERIO,A, ZAPPELLA,M. BRIT J PSYCHIAT, 145(AUG), 227 - 228.

    1983

    • SKUSE DH (1983). A PRIMER OF CHILD-PSYCHOTHERAPY, 2ND EDITION - ADAMS,PL. BRIT J PSYCHIAT, 143(AUG), 207 - 207.

    1982

    • SKUSE DH (1982). VIOLENCE AND CRIME IN THE SCHOOLS - BAKER,K, RUBEL,RJ. BEHAV PSYCHOTHER, 10(4), 378 - 379.
    • SKUSE DH (1982). MINIMAL BRAIN-DYSFUNCTION - A PROSPECTIVE-STUDY - NICHOLS,PL, CHEN,TC. BRIT J PSYCHIAT, 140(MAY), 541 - 541.

    1975

    • Skuse DH (1975). Attitudes to the psychiatric outpatient clinic.. Br Med J, 3(5981), 469 - 471.

    • Skuse DH, Seigal A (). Behavioural Phenotypes and Chromosomal Disorders. In (Ed.), Child and Adolescent Psychiatry 5th edition (pp. - ). : Blackwell Publishing, Oxford.
    • Gallagher L, Skuse DH (). Genetic influences on the neural substrates of social cognition. In Szekely T, Komdeur JM, A J (Ed.), Social behaviour: genes, ecology and evolution (pp. - ). : Cambridge University Press.
    • Skuse DH (). Myths about Autism. In Steinhausen HC, Gundelfinger RW (Ed.), Autismus Spektrum Storungen (pp. - ). : Kohlhammer GmbH.Stuttgart.
    • Tansey KE, Brookes KJ, Hill MJ, Cochrance LE, Skuse DH, Correia C, Vicente A, Kent L, Gallagher L, Anney RJ (). Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: genetic and molecular studies. Neuroscience Letters, 474(3), 163 - 167.
    • Skuse DH, Warrington RH (). Status and Progress Monitoring System for Computer Based interviewing.
    • Skuse DH, Gallagher L (). Social and Genetic Aspects of Turners, Williams and Fragile X syndrome. In de Haan M, gunnar MR (Ed.), Handbook of Developmental Social Neuroscience (pp. - ). : Guilford Press New York.
    • Skuse DH (). Social Cognition and School Exclusion.
    • Donno R, Parker G, Gilmour J, Skuse DH (). Social communication deficits in disruptive primary-school children. British Journal of Psychiatry, 196, 282 - 289.
    • Santosh PJ, Mandy WPL, Puura K, Kaartinen M, Warrington R, Skuse DH (). The construction and validation of a short form of the developmental, diagnostic and dimensional interview. European Child and Adolescent Psychiatry, , - . doi:10.1007/s00787-009-0004-0
    • Salter G, Seigal A, Claxton M, Lawrence K, Skuse DH (). Perception of action by animated shapes in autism spectrum disorders. Autism, , - .