Prof Philippa Talmud

Photo

Personal Profile

Name: Philippa Talmud Email: p.talmud@ucl.ac.uk
Title: Prof Tel: 0207 679 6968
Department: Centre for Cardiovascular Genetics Fax: 0207 679 6212
Position: Professor of Cardiovascular Genetics Address: Centre for Cardiovascular Genetics , Rayne Building, 5 University St, London, WC1E 6JF
Research Domain: Cardiometabolic Science Web Page: Personal Web Page

Profile

Research Description

I head the Lipid Subgroup within the Centre for Cardiovascular Genetics, in the newly formed Institute of Cardiovascular Science. The focus of the work has been the study of genes involved in lipid metabolism and their contribution to heart disease risk. Initial studies were carried out to compare the effect of genetic variation at the apoE, apoB, AI-CIII-AIV-AV and lipoprotein lipase loci on variation in lipid levels in the general population, focusing on interaction with environmental modulators. More recently the studies have diversified to test, both in vivo and in vitro, the molecular mechanisms of specific mutations identified in these and other candidate genes using prokaryotic and tissue culture expression systems. We are now testing the efficacy of using genetic information for CHD calibration, precision and risk prediction. We are part of UCLEB, a consortium formed including researchers from  UCL/Edinburgh and Bristol to bring together the large prospective studies that together number >30,000 individuals followed for 10-30 years. These studies are richly phenotyped and we have used both the 50K Cardiochip and 200K Metabochip to genotype these studies. We are using a gene score approach to examine the association with Cardiovascular risk factors and events.
I also have an interest in Gene Ontology and have a small group working with me annotating genes involved in Cardiovascular Processes, funded by the British Heart Foundation.


Research Activities

Cardiovascular Genetics

Epidemiology of cardiovascular disease

cardiovascular epidemiology

Education Description

My educational interests are the Genetics of Cardiovascular Disease, encompassing both common and rare variants. I am also interested in the interaction of environmental factors with CHD risk genes.
I teach on the undergraduate   Human Genetics and Biochemistry of Lipids courses and the Molecular Medicine MSc.I am on the teaching executive of the MSc in Complex Diseases and run the Cardiovascular Genetics Module. I am chairperson of the newly developed MSc in Cardiovascular Science which will be run by the Institute of Cardiovascular Science starting 2012.  I supervise several BSc and MSc students who undertake research projects in our lab.

I am committed to mentoring and feel that such a scheme which supports, inspires and guides postdoctoral fellows and PhD studnets benefits their   careers both in the Institute and in the scientific community as

a whole and improves the morale of the Insititute.




 





UCL Collaborators

Dr Anne Peasey; Dr Fiona Lampe; Prof Richard Morris; Dr Olga Vikhireva; Dr Ann Walker; Prof Steve Humphries

External Collaborators

Publications

    2013

    • Walker A, Unger C, Howard P, Cooper J, Palmen J, Li K-W, Yin D, McLachlan S, Talmud P, Steve H (2013). ASSOCIATION BETWEEN HFE P.(C282Y) AND CORONARY HEART DISEASE IN THE NPHSII COHORT: INTERACTION WITH SMOKING. AMERICAN JOURNAL OF HEMATOLOGY, 88(5), E221 - E222.
    • Khan TA, Shah T, Prieto D, Zhang W, Price J, Fowkes GR, Cooper J, Talmud PJ, Humphries SE, Sundstrom J, Hubacek JA, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Abdollahi MR, Slooter AJ, Szolnoki Z, Sandhu M, Wareham N, Frikke-Schmidt R, Tybjærg-Hansen A, Fillenbaum G, Heijmans BT, Katsuya T, Gromadzka G, Singleton A, Ferrucci L, Hardy J, Worrall B, Rich SS, Matarin M, Whittaker J, Gaunt TR, Whincup P, Morris R, Deanfield J, Donald A, Davey Smith G, Kivimaki M, Kumari M, Smeeth L, Khaw KT, Nalls M, Meschia J, Sun K, Hui R, Day I, Hingorani AD, Casas JP (2013). Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.. Int J Epidemiol, 42(2), 475 - 492. doi:10.1093/ije/dyt034
    • Hu Y, Li L, Ehm MG, Bing N, Song K, Nelson MR, Talmud PJ, Hingorani AD, Kumari M, Kivimäki M, Xu CF, Waterworth DM, Whittaker JC, Abecasis GR, Spino C, Kang HM (2013). The benefits of using genetic information to design prevention trials.. Am J Hum Genet, 92(4), 547 - 557. doi:10.1016/j.ajhg.2013.03.003
    • Shah T, Zabaneh D, Gaunt T, Swerdlow DI, Shah S, Talmud PJ, Day IN, Whittaker J, Holmes MV, Sofat R, Humphries SE, Kivimaki M, Kumari M, Hingorani AD, Casas JP (2013). Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.. Circ Cardiovasc Genet, 6(2), 163 - 170. doi:10.1161/CIRCGENETICS.112.964254
    • Blake JA, Dolan M, Drabkin H, Hill DP, Ni L, Sitnikov D, Bridges S, Burgess S, Buza T, McCarthy F, Peddinti D, Pillai L, Carbon S, Dietze H, Ireland A, Lewis SE, Mungall CJ, Gaudet P, Chisholm RL, Fey P, Kibbe WA, Basu S, Siegele DA, McIntosh BK, Renfro DP, Zweifel AE, Hu JC, Brown NH, Tweedie S, Alam-Faruque Y, Apweiler R, Auchinchloss A, Axelsen K, Bely B, Blatter M-C, Bonilla C, Bougueleret L, Boutet E, Breuza L, Bridge A, Chan WM, Chavali G, Coudert E, Dimmer E, Estreicher A, Famiglietti L, Feuermann M, Gos A, Gruaz-Gumowski N, Hieta R, Hinz U, Hulo C, Huntley R, James J, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, Martin MJ, Masson P, Mutowo-Muellenet P, O'Donovan C, Pedruzzi I, Pichler K, Poggioli D, Millan PP, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Stutz A, Sundaram S, Tognolli M, Xenarios I, Foulger R, Lomax J, Roncaglia P, Khodiyar VK, Lovering RC, Talmud PJ, Chibucos M, Giglio MG, Chang H-Y, Hunter S, McAnulla C, Mitchell A, Sangrador A, Stephan R, Harris MA, Oliver SG, Rutherford K, Wood V, Bahler J, Lock A, Kersey PJ, McDowall MD, Staines DM, Dwinell M, Shimoyama M, Laulederkind S, Hayman T, Wang S-J, Petri V, Lowry T, D'Eustachio P, Matthews L, Balakrishnan R, Binkley G, Cherry JM, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hitz BC, Hong EL, Karra K, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng S, Wong ED, Berardini TZ, Li D, Huala E, Mi H, Thomas PD, Chan J, Kishore R, Sternberg P, Van Auken K, Howe D, Westerfield M, Consortium GO (2013). Gene Ontology Annotations and Resources. NUCLEIC ACIDS RESEARCH, 41(D1), D530 - D535. doi:10.1093/nar/gks1050
    • Shah S, Casas JP, Drenos F, Whittaker J, Deanfield J, Swerdlow DI, Holmes MV, Kivimaki M, Langenberg C, Wareham N, Gertow K, Sennblad B, Strawbridge RJ, Baldassarre D, Veglia F, Tremoli E, Gigante B, de Faire U, Kumari M, Talmud PJ, Hamsten A, Humphries SE, Hingorani AD (2013). Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.. Circ Cardiovasc Genet, 6(1), 63 - 72. doi:10.1161/CIRCGENETICS.112.963140
    • Shah S, Casas JP, Gaunt TR, Cooper J, Drenos F, Zabaneh D, Swerdlow DI, Shah T, Sofat R, Palmen J, Kumari M, Kivimaki M, Ebrahim S, Smith GD, Lawlor DA, Talmud PJ, Whittaker J, Day IN, Hingorani AD, Humphries SE (2013). Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.. Eur Heart J, 34(13), 972 - 981. doi:10.1093/eurheartj/ehs243
    • Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, Matthews MK, Palmen J, Norata GD, O'Reilly PF, Saleheen D, Amin N, Balmforth AJ, Beekman M, de Boer RA, Böhringer S, Braund PS, Burton PR, Craen AJ, Denniff M, Dong Y, Douroudis K, Dubinina E, Eriksson JG, Garlaschelli K, Guo D, Hartikainen AL, Henders AK, Houwing-Duistermaat JJ, Kananen L, Karssen LC, Kettunen J, Klopp N, Lagou V, van Leeuwen EM, Madden PA, Mägi R, Magnusson PK, Männistö S, McCarthy MI, Medland SE, Mihailov E, Montgomery GW, Oostra BA, Palotie A, Peters A, Pollard H, Pouta A, Prokopenko I, Ripatti S, Salomaa V, Suchiman HE, Valdes AM, Verweij N, Viñuela A, Wang X, Wichmann HE, Widen E, Willemsen G, Wright MJ, Xia K, Xiao X, van Veldhuisen DJ, Catapano AL, Tobin MD, Hall AS, Blakemore AI, van Gilst WH, Zhu H, Consortium C, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Talmud PJ, Pedersen NL, Perola M, Ouwehand W, Kaprio J, Martin NG, van Duijn CM, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Jarvelin MR, Slagboom PE, Thompson JR, Spector TD, van der Harst P, Samani NJ (2013). Identification of seven loci affecting mean telomere length and their association with disease.. Nat Genet, 45(4), 422 - 427e2. doi:10.1038/ng.2528
    • Talmud PJ, Shah S, Whittall R, Futema M, Howard P, Cooper JA, Harrison SC, Li K, Drenos F, Karpe F, Neil HA, Descamps OS, Langenberg C, Lench N, Kivimaki M, Whittaker J, Hingorani AD, Kumari M, Humphries SE (2013). Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.. Lancet, 381(9874), 1293 - 1301. doi:10.1016/S0140-6736(12)62127-8

    2012

    • Harrison SC, Zabaneh D, Asselbergs FW, Drenos F, Jones GT, Shah S, Gertow K, Sennblad B, Strawbridge RJ, Gigante B, Holewijn S, De Graaf J, Vermeulen S, Folkersen L, van Rij AM, Baldassarre D, Veglia F, Talmud PJ, Deanfield JE, Agu O, Kivimaki M, Kumari M, Bown MJ, Nyyssönen K, Rauramaa R, Smit AJ, Franco-Cereceda A, Giral P, Mannarino E, Silveira A, Syvänen A-C, de Borst GJ, van der Graaf Y, de Faire U, Baas AF, Blankensteijn JD, Wareham NJ, Fowkes G, Tzoulaki I, Price JF, Tremoli E, Hingorani AD, Eriksson P, Hamsten A, Humphries SE (2012). A gene-centric study of common carotid artery remodelling. Atherosclerosis, , - .
    • Blake JA, Dolan M, Drabkin H, Hill DP, Ni L, Sitnikov D, Burgess S, Buza T, Gresham C, McCarthy F, Pillai L, Wang H, Carbon S, Lewis SE, Mungall CJ, Gaudet P, Chisholm RL, Fey P, Kibbe WA, Basu S, Siegele DA, McIntosh BK, Renfro DP, Zweifel AE, Hu JC, Brown NH, Tweedie S, Alam-Faruque Y, Apweiler R, Auchinchloss A, Axelsen K, Argoud-Puy G, Bely B, Blatter M-C, Bougueleret L, Boutet E, Branconi-Quintaje S, Breuza L, Bridge A, Browne P, Chan WM, Coudert E, Cusin I, Dimmer E, Duek-Roggli P, Eberhardt R, Estreicher A, Famiglietti L, Ferro-Rojas S, Feuermann M, Gardner M, Gos A, Gruaz-Gumowski N, Hinz U, Hulo C, Huntley R, James J, Jimenez S, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, Martin MJ, Masson P, Moinat M, O'Donovan C, Pedruzzi I, Pichler K, Poggioli D, Millan PP, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Sehra H, Stanley E, Stutz A, Sundaram S, Tognolli M, Xenarios I, Foulger R, Lomax J, Roncaglia P, Camon E, Khodiyar VK, Lovering RC, Talmud PJ, Chibucos M, Giglio MG, Dolinski K, Heinicke S, Livstone MS, Stephan R, Harris MA, Oliver SG, Rutherford K, Wood V, Bahler J, Lock A, Kersey PJ, McDowall MD, Staines DM, Dwinell M, Shimoyama M, Laulederkind S, Hayman T, Wang S-J, Petri V, Lowry T, D'Eustachio P, Matthews L, Amundsen CD, Balakrishnan R, Binkley G, Cherry JM, Christie KR, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hitz BC, Hong EL, Karra K, Krieger CJ, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng S, Wong ED, Berardini TZ, Li D, Huala E, Slonim D, Wick H, Thomas P, Chan J, Kishore R, Sternberg P, Van Auken K, Howe D, Westerfield M, Consortium GO (2012). The Gene Ontology: enhancements for 2011. NUCLEIC ACIDS RESEARCH, 40(D1), D559 - D564. doi:10.1093/nar/gkr1028
    • Costelloe SJ, El-Sayed Moustafa JS, Drenos F, Palmen J, Li Q, Whiting S, Thomas M, Kivimaki M, Kumari M, Hingorani AD, Tzoulaki I, Järvelin MR, Ruokonen A, Hartikainen AL, Pouta A, Walters RG, Blakemore AI, Humphries SE, Coin LJ, Talmud PJ (2012). Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.. Circ Cardiovasc Genet, 5(5), 555 - 560. doi:10.1161/CIRCGENETICS.111.961037
    • Asselbergs F, Guo Y, van Iperen EA, Sivapalaratnam S, Tragante V, Lanktree M, Lange L, Almoguera B, Appelman Y, Barnard J, Baumert J, Beitelshees A, Bhangale T, Chen Y-D, Gaunt T, Gong Y, Hopewell J, Johnson T, Kleber M, Langaee T, Li M, Li Y, Liu K, McDonough C, Meijs ML, Middelberg RS, Musunuru K, Nelson C, O'Connell J, Padmanabhan S, Pankow J, Pankratz N, Rafelt S, Rajagopalan R, Romaine SR, Schork N, Shaffer J, Shen H, Smith E, Tischfield S, van der Most P, van Vliet-Ostaptchouk J, Verweij N, Volcik K, Zhang L, Bailey K, Bailey K, Bauer F, Boer JA, Braund P, Burt A, Burton P, Buxbaum S, Chen W, Cooper-DeHoff R, Cupples L, deJong J, Delles C, Duggan D, Fornage M, Furlong C, Glazer N, Gums J, Hastie C, Holmes M, Illig T, Kirkland S, Kivimaki M, Klein R, Klein B, Kooperberg C, Kottke-Marchant K, Kumari M, LaCroix A, Mallela L, Murugesan G, Ordovas J, Ouwehand W, Post W, Saxena R, Scharnagl H, Schreiner P, Shah T, Shields D, Shimbo D, Srinivasan S, Stolk R, Swerdlow D, Taylor Jr H, Topol E, Toskala E, van Pelt J, van Setten J, Yusuf S, Whittaker J, Zwinderman AH, Anand S, Balmforth A, Berenson G, Bezzina C, Boehm B, Boerwinkle E, Casas J, Caulfield M, Clarke R, Connell J, Cruickshanks K, Davidson K, Day IM, de Bakker PW, Doevendans P, Dominiczak A, Hall A, Hartman C, Hengstenberg C, Hillege H, Hofker M, Humphries S, Jarvik G, Johnson J, Kaess B, Kathiresan S, Koenig W, Lawlor D, März W, Melander O, Mitchell B, Montgomery G, Munroe P, Murray S, Newhouse S, Onland-Moret N, Poulter N, Psaty B, Redline S, Rich S, Rotter J, Schunkert H, Sever P, Shuldiner A, Silverstein R, Stanton A, Thorand B, Trip M, Tsai M, van der Harst P, van der Schoot E, van der Schouw Y, Verschuren WM, Watkins H, Wilde AM, Wolffenbuttel BR, Whitfield J, Hovingh G, Ballantyne C, Wijmenga C, Reilly M, Martin N, Wilson J, Rader D, Samani N, Reiner A, Hegele R, Kastelein JP, Hingorani A, Talmud P, Hakonarson H, Elbers C, Keating B, Drenos F (2012). Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci. American Journal of Human Genetics, , - .
    • Smith AJP, Howard P, Shah S, Eriksson P, Stender S, Giambartolomei C, Folkersen L, Tybjærg-Hansen A, Kumari M, Palmen J, Hingorani AD, Talmud PJ, Humphries SE (2012). Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays. PLoS Genetics, 8(8), - .
    • Walker AP, Fowkes RC, Saleh F, Kim SH, Wilkinson P, Cabrera-Sharp V, Talmud PJ, Humphries SE, Looijenga LH, Bouloux PM (2012). Genetic analysis of NR0B1 in congenital adrenal hypoplasia patients: identification of a rare regulatory variant resulting in congenital adrenal hypoplasia and hypogonadal hypogonadism without testicular carcinoma in situ.. Sex Dev, 6(6), 284 - 291. doi:10.1159/000342295
    • Exeter HJ, Folkersen L, Palmen J, Franco-Cereceda A, Cooper JA, Kalea AZ, Hooft FV, Eriksson P, Humphries SE, Talmud PJ (2012). Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels.. PLoS One, 7(7), e41139 - . doi:10.1371/journal.pone.0041139
    • Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium , Hingorani AD, Casas JP (2012). The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.. Lancet, 379(9822), 1214 - 1224. doi:10.1016/S0140-6736(12)60110-X
    • Papp AC, Pinsonneault JK, Wang D, Newman LC, Gong Y, Johnson JA, Pepine CJ, Kumari M, Hingorani AD, Talmud PJ, Shah S, Humphries SE, Sadee W (2012). Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.. PLoS One, 7(3), e31930 - . doi:10.1371/journal.pone.0031930
    • Kalea AZ, Harrison SC, Stephens JW, Talmud PJ (2012). Genetic susceptibility for coronary heart disease and type 2 diabetes complications.. Clin Chem, 58(5), 818 - 820. doi:10.1373/clinchem.2012.182725
    • Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM, Look AHEAD Research Group , DIAGRAM consortium , Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ (2012). Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.. Am J Hum Genet, 90(3), 410 - 425. doi:10.1016/j.ajhg.2011.12.022
    • Talmud PJ (2012). Commentary on the paper by Gustavsson et al. entitled 'Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women'.. Atherosclerosis, 220(2), 323 - 324. doi:10.1016/j.atherosclerosis.2011.10.024
    • Yiannakouris N, Cooper JA, Shah S, Drenos F, Ireland HA, Stephens JW, Li KW, Elkeles R, Godsland IF, Kivimaki M, Hingorani AD, Kumari M, Talmud PJ, Humphries SE (2012). IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.. Nutr Metab Cardiovasc Dis, 22(12), 1024 - 1030. doi:10.1016/j.numecd.2011.05.009
    • Angelakopoulou A, Shah T, Sofat R, Shah S, Berry DJ, Cooper J, Palmen J, Tzoulaki I, Wong A, Jefferis BJ, Maniatis N, Drenos F, Gigante B, Hardy R, Laxton RC, Leander K, Motterle A, Simpson IA, Smeeth L, Thomson A, Verzilli C, Kuh D, Ireland H, Deanfield J, Caulfield M, Wallace C, Samani N, Munroe PB, Lathrop M, Fowkes FG, Marmot M, Whincup PH, Whittaker JC, de Faire U, Kivimaki M, Kumari M, Hypponen E, Power C, Humphries SE, Talmud PJ, Price J, Morris RW, Ye S, Casas JP, Hingorani AD (2012). Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.. Eur Heart J, 33(3), 393 - 407. doi:10.1093/eurheartj/ehr225
    • Harrison SC, Cooper JA, Li K, Talmud PJ, Sofat R, Stephens JW, Hamsten A, HIFMECH Consortium , Sanders J, Montgomery H, Neil A, Simon Broome Research Consortium , Humphries SE (2012). Association of a sequence variant in DAB2IP with coronary heart disease.. Eur Heart J, 33(7), 881 - 888. doi:10.1093/eurheartj/ehr075
    • Pillay N, Plagnol V, Tarpey PS, Lobo SB, Presneau N, Szuhai K, Halai D, Berisha F, Cannon SR, Mead S, Kasperaviciute D, Palmen J, Talmud PJ, Kindblom LG, Amary MF, Tirabosco R, Flanagan AM (2012). A common single-nucleotide variant in T is strongly associated with chordoma.. Nat Genet, 44(11), 1185 - 1187. doi:10.1038/ng.2419
    • Gaunt TR, Shah S, Nelson CP, Drenos F, Braund PS, Adeniran I, Folkersen L, Lawlor DA, Casas JP, Amuzu A, Kivimaki M, Whittaker J, Eriksson P, Zhang H, Hancox JC, Tomaszewski M, Burton PR, Tobin MD, Humphries SE, Talmud PJ, Macfarlane PW, Hingorani AD, Samani NJ, Kumari M, Day IN (2012). Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.. Circ Cardiovasc Genet, 5(6), 630 - 638. doi:10.1161/CIRCGENETICS.112.962852

    2011

    • Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I, O'Brien ET, Poulter NR, Sever P, Shields DC, Thom S, Wannamethee SG, Whincup PH, Brown MJ, Connell JM, Dobson RJ, Howard PJ, Mein CA, Onipinla A, Shaw-Hawkins S, Zhang Y, Davey Smith G, Day IN, Lawlor DA, Goodall AH, Cardiogenics Consortium , Fowkes FG, Abecasis GR, Elliott P, Gateva V, Global BPgen Consortium , Braund PS, Burton PR, Nelson CP, Tobin MD, van der Harst P, Glorioso N, Neuvrith H, Salvi E, Staessen JA, Stucchi A, Devos N, Jeunemaitre X, Plouin PF, Tichet J, Juhanson P, Org E, Putku M, Sõber S, Veldre G, Viigimaa M, Levinsson A, Rosengren A, Thelle DS, Hastie CE, Hedner T, Lee WK, Melander O, Wahlstrand B, Hardy R, Wong A, Cooper JA, Palmen J, Chen L, Stewart AF, Wells GA, Westra HJ, Wolfs MG, Clarke R, Franzosi MG, Goel A, Hamsten A, Lathrop M, Peden JF, Seedorf U, Watkins H, Ouwehand WH, Sambrook J, Stephens J, Casas JP, Drenos F, Holmes MV, Kivimaki M, Shah S, Shah T, Talmud PJ, Whittaker J, Wallace C, Delles C, Laan M, Kuh D, Humphries SE, Nyberg F, Cusi D, Roberts R, Newton-Cheh C, Franke L, Stanton AV, Dominiczak AF, Farrall M, Hingorani AD, Samani NJ, Caulfield MJ, Munroe PB (2011). Blood pressure loci identified with a gene-centric array.. Am J Hum Genet, 89(6), 688 - 700. doi:10.1016/j.ajhg.2011.10.013
    • De Caterina R, Talmud PJ, Merlini PA, Foco L, Pastorino R, Altshuler D, Mauri F, Peyvandi F, Lina D, Kathiresan S, Bernardinelli L, Ardissino D, Gruppo Italiano Aterosclerosi (2011). Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction.. Atherosclerosis, 214(2), 397 - 403. doi:10.1016/j.atherosclerosis.2010.11.011
    • Shah S, Nelson CP, Gaunt TR, van der Harst P, Barnes T, Braund PS, Lawlor DA, Casas JP, Padmanabhan S, Drenos F, Kivimaki M, Talmud PJ, Humphries SE, Whittaker J, Morris RW, Whincup PH, Dominiczak A, Munroe PB, Johnson T, Goodall AH, Cambien F, Diemert P, Hengstenberg C, Ouwehand WH, Felix JF, Glazer NL, Tomaszewski M, Burton PR, Tobin MD, van Veldhuisen DJ, de Boer RA, Navis G, van Gilst WH, Mayosi BM, Thompson JR, Kumari M, MacFarlane PW, Day IN, Hingorani AD, Samani NJ (2011). Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.. Circ Cardiovasc Genet, 4(6), 626 - 635. doi:10.1161/CIRCGENETICS.111.960203
    • International Consortium for Blood Pressure Genome-Wide Association Studies , Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, CARDIoGRAM consortium , CKDGen Consortium , KidneyGen Consortium , EchoGen consortium , CHARGE-HF consortium , Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stančáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Harti (2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.. Nature, 478(7367), 103 - 109. doi:10.1038/nature10405
    • Holmes MV, Newcombe P, Hubacek JA, Sofat R, Ricketts SL, Cooper J, Breteler MM, Bautista LE, Sharma P, Whittaker JC, Smeeth L, Fowkes FG, Algra A, Shmeleva V, Szolnoki Z, Roest M, Linnebank M, Zacho J, Nalls MA, Singleton AB, Ferrucci L, Hardy J, Worrall BB, Rich SS, Matarin M, Norman PE, Flicker L, Almeida OP, van Bockxmeer FM, Shimokata H, Khaw KT, Wareham NJ, Bobak M, Sterne JA, Smith GD, Talmud PJ, van Duijn C, Humphries SE, Price JF, Ebrahim S, Lawlor DA, Hankey GJ, Meschia JF, Sandhu MS, Hingorani AD, Casas JP (2011). Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.. Lancet, 378(9791), 584 - 594. doi:10.1016/S0140-6736(11)60872-6
    • Kilpeläinen TO, Zillikens MC, Stančákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Döring A, Eiriksdottir G, Estrada K, Fernández-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimäki M, Klopp N, Kühnel B, Kuusisto J, Liu Y, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellström D, Mitchell BD, Mooser V, Moreno JM, Männistö S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvänen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJ (2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.. Nat Genet, 43(8), 753 - 760. doi:10.1038/ng.866
    • Zabaneh D, Kumari M, Sandhu M, Wareham N, Wainwright N, Papamarkou T, Hopewell J, Clarke R, Li K, Palmen J, Talmud PJ, Kronenberg F, Lamina C, Summerer M, Paulweber B, Price J, Fowkes G, Stewart M, Drenos F, Shah S, Shah T, Casas JP, Kivimaki M, Whittaker J, Hingorani AD, Humphries SE (2011). Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.. Atherosclerosis, 217(2), 447 - 451. doi:10.1016/j.atherosclerosis.2011.04.015
    • Zabaneh D, Gaunt TR, Kumari M, Drenos F, Shah S, Berry D, Power C, Hypponen E, Shah T, Palmen J, Pallas J, Talmud PJ, Casas JP, Sofat R, Lowe G, Rumley A, Morris RW, Whincup PH, Rodriguez S, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Kivimaki M, Whittaker J, Hingorani AD, Day IN, Humphries SE (2011). Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.. Ann Hum Genet, 75(4), 456 - 467. doi:10.1111/j.1469-1809.2011.00654.x
    • Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS) , Chakravarti A, Zhu X, Levy D (2011). Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.. Hum Mol Genet, 20(11), 2273 - 2284. doi:10.1093/hmg/ddr092
    • Talmud PJ, Cooper JA, Gaunt T, Holmes MV, Shah S, Palmen J, Drenos F, Shah T, Kumari M, Kivimaki M, Whittaker J, Lawlor DA, Day IN, Hingorani AD, Casas JP, Humphries SE (2011). Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies.. Diabetologia, 54(7), 1710 - 1719. doi:10.1007/s00125-011-2108-6
    • Eisenberg DT, Salpea KD, Kuzawa CW, Hayes MG, Humphries SE, European Atherosclerosis Research Study II Group (2011). Substantial variation in qPCR measured mean blood telomere lengths in young men from eleven European countries.. Am J Hum Biol, 23(2), 228 - 231. doi:10.1002/ajhb.21126
    • Quint JK, Donaldson GC, Kumari M, Talmud PJ, Hurst JR (2011). SERPINA1 11478G→A variant, serum α1-antitrypsin, exacerbation frequency and FEV1 decline in COPD.. Thorax, 66(5), 418 - 424. doi:10.1136/thx.2010.152975
    • Holmes MV, Harrison S, Talmud PJ, Hingorani AD, Humphries SE (2011). Utility of genetic determinants of lipids and cardiovascular events in assessing risk.. Nat Rev Cardiol, 8(4), 207 - 221. doi:10.1038/nrcardio.2011.6
    • Wensley F, Gao P, Burgess S, Kaptoge S, Di Angelantonio E, Shah T, Engert JC, Clarke R, Davey-Smith G, Nordestgaard BG, Saleheen D, Samani NJ, Sandhu M, Anand S, Pepys MB, Smeeth L, Whittaker J, Casas JP, Thompson SG, Hingorani AD, Danesh J, Eiriksdottir G, Harris TB, Launer LJ, Gudnason V, Folsom AR, Andrews G, Ballantyne CM, Samani NJ, Hall AS, Braund PS, Balmforth AJ, Whincup PH, Morris R, Lawlor DA, Lowe GDO, Timpson N, Ebrahim S, Ben-Shlomo Y, Davey-Smith G, Timpson N, Nordestgaard BG, Tybjaerg-Hansen A, Zacho J, Brown M, Sandhu M, Ricketts SL, Ashford S, Lange L, Reiner A, Cushman M, Tracy R, Wu C, Ge J, Zou Y, Sun A, Hung J, McQuillan B, Thompson P, Beilby J, Warrington N, Palmer LJ, Wanner C, Drechsler C, Hoffmann MM, Fowkes FGR, Lowe GDO, Tzoulaki I, Kumari M, Miller M, Marmot M, Onland-Moret C, van der Schouw YT, Boer JM, Wijmenga C, Ricketts L, Ashford S, Sandhu M, Khaw KT, Vasan RS, Schnabel RB, Yamamoto JF, Benjamin EJ, Schunkert H, Erdmann J, Konig IR, Hengstenberg C, Chiodini B, Franzosi MG, Pietri S, Gori F, Rudock M, Liu Y, Lohman K, Harris TB, Humphries SE, Hamsten A, Norman PE, Hankey GJ, Jamrozik K, Palmer LJ, Rimm EB, Pai JK, Psaty BM, Heckbert SR, Bis JC, Yusuf S, Anand S, Engert JC, Xie C, Collins R, Clarke R, Bennett D, Kooner J, Chambers J, Elliott P, Marz W, Kleber ME, Bohm BO, Winkelmann BR, Melander O, Berglund G, Koenig W, Thorand B, Baumert J, Peters A, Rimm EB, Manson J, Pai JK, Humphries SE, Cooper JA, Talmud PJ, Ladenvall P, Johansson L, Jansson JH, Hallmans G, Reilly MP, Qu L, Li M, Rader DJ, Watkins H, Clarke R, Hopewell J, Saleheen D, Danesh J, Frossard P, Sattar N, Robertson M, Shepherd J, Schaefer E, Hofman A, Witteman JCM, Kardys I, Dehghan A, de Faire U, Bennet A, Gigante B, Leander K, Ben-Shlomo Y, Davey-Smith G, Timpson N, Peters B, Maitland-van der Zee AH, de Boer A, Klungel O, Reiner A, Manson J, Greenland P, Dai J, Liu S, Kumari M, Brunner E, Kivimaki M, Marmot M, Sattar N, O'Reilly D, Ford I, Packard CJ, C Reactive Prot Coronary Heart Dis , AGES , ARIC , BHF-FHS , BRHS , BWHHS , CAPS , CCHS CGPS CIHDS , CHAOS , CHS , CRPHANS , CUDAS CUPID , 4D , EAS , ELSA , EPICNL , EPICNOR , FRAMOFF , GERMIFS , GISSI-P , HEALTHABC , HIFMECH , HIMS , HPFS , HVHS , INTERHEART , ISIS , LOLIPOP , LURIC , MALMO , MONICAKORA , NHS , NPHSII , NSC , PENNCATH , PROCARDIS , PROMIS , PROSPER , ROTTERDAM , SHEEP , SPEED , UCP , WHIOS , WHITEII , WOSCOPS (2011). Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BRIT MED J, 342, - . doi:10.1136/bmj.d548
    • Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer AD, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszewski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn GW, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ, Hugh Watkins on behalf of PROCARDIS , Grant SF, Munroe PB, North KE, Samani NJ, Koenig W, Gaunt TR, Anand SS, van der Schouw YT, Meena Kumari on behalf of the Whitehall II Study and the WHII 50K Group , Soranzo N, Fitzgerald GA, Reiner A, Hegele RA, Hakonarson H, Keating BJ (2011). Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.. Am J Hum Genet, 88(1), 6 - 18. doi:10.1016/j.ajhg.2010.11.007
    • Talmud PJ, Yiannakouris N, Humphries SE (2011). Lipoprotein association studies: taking stock and moving forward.. Curr Opin Lipidol, 22(2), 106 - 112. doi:10.1097/MOL.0b013e3283423f81
    • Smart MC, Dedoussis G, Yiannakouris N, Grisoni ML, Dror GK, Yannakoulia M, Papoutsakis C, Louizou E, Mantzoros CS, Melistas L, Kontogianni MD, Cooper JA, Humphries SE, Talmud PJ, EARSII Consortium (2011). Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures.. Nutr Metab Cardiovasc Dis, 21(7), 476 - 484. doi:10.1016/j.numecd.2009.12.004
    • Alam-Faruque Y, Huntley RP, Khodiyar VK, Camon EB, Dimmer EC, Sawford T, Martin MJ, O'Donovan C, Talmud PJ, Scambler P, Apweiler R, Lovering RC (2011). The impact of focused Gene Ontology curation of specific mammalian systems.. PLoS One, 6(12), e27541 - . doi:10.1371/journal.pone.0027541
    • Ravandi A, Boekholdt SM, Mallat Z, Talmud PJ, Kastelein JJ, Wareham NJ, Miller ER, Benessiano J, Tedgui A, Witztum JL, Khaw KT, Tsimikas S (2011). Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study.. J Lipid Res, 52(10), 1829 - 1836. doi:10.1194/jlr.M015776
    • Smart-Halajko MC, Kelley-Hedgepeth A, Montefusco MC, Cooper JA, Kopin A, McCaffrey JM, Balasubramanyam A, Pownall HJ, Nathan DM, Peter I, Talmud PJ, Huggins GS, Look AHEAD Study (2011). ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial.. BMC Med Genet, 12, 89 - . doi:10.1186/1471-2350-12-89
    • Khodiyar VK, Hill DP, Howe D, Berardini TZ, Tweedie S, Talmud PJ, Breckenridge R, Bhattarcharya S, Riley P, Scambler P, Lovering RC (2011). The representation of heart development in the gene ontology.. Dev Biol, 354(1), 9 - 17. doi:10.1016/j.ydbio.2011.03.011
    • Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sober S, Parsa A, Luan JA, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WHL, Sjogren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu YM, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KDH, Lehtimaki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CGP, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CSPM, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YPC, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day INM, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li YL, Young JH, Bis JC, Kahonen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JAH, Kottgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grassler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso IS, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Artigas MS, Dong YB, Snieder H, Wang XL, Zhu HD, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang WH, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancakova A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NRG, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJL, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FUS, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikainen LP, Soininen P, Tukiainen T, Wurtz P, Ong RTH, Dorr M, Kroemer HK, Volker U, Volzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai GJ, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MVK, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FGR, Charchar FJ, Schwarz PEH, Hayward C, Guo XQ, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu XF, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJG, Altshuler D, Loos RJF, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JCM, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Jarvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caul (2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. NATURE, 478(7367), 103 - 109. doi:10.1038/nature10405

    2010

    • Smart MC, Dedoussis G, Louizou E, Yannakoulia M, Drenos F, Papoutsakis C, Maniatis N, Humphries SE, Talmud PJ (2010). APOE, CETP and LPL genes show strong association with lipid levels in Greek children.. Nutr Metab Cardiovasc Dis, 20(1), 26 - 33. doi:10.1016/j.numecd.2009.02.005
    • Gomaraschi M, Putt WE, Pozzi S, Iametti S, Barbiroli A, Bonomi F, Favari E, Bernini F, Franceschini G, Talmud PJ, Calabresi L (2010). Structure and function of the apoA-IV T347S and Q360H common variants. Biochem.Biophys.Res.Commun., 393(1), 126 - 130.
    • Smart-Halajko MC, Robciuc MR, Cooper JA, Jauhiainen M, Kumari M, Kivimaki M, Khaw KT, Boekholdt SM, Wareham NJ, Gaunt TR, Day IN, Braund PS, Nelson CP, Hall AS, Samani NJ, Humphries SE, Ehnholm C, Talmud PJ (2010). The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk.. Arterioscler Thromb Vasc Biol, 30(11), 2277 - 2282. doi:10.1161/ATVBAHA.110.212209
    • Ken-Dror G, Drenos F, Humphries SE, Talmud PJ, Hingorani AD, Kivimäki M, Kumari M, Bauer KA, Morrissey JH, Ireland HA (2010). Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.. J Thromb Haemost, 8(11), 2394 - 2403. doi:10.1111/j.1538-7836.2010.04035.x
    • Sofat R, Casas JP, Kumari M, Talmud PJ, Ireland H, Kivimaki M, Marmot M, Hughes AD, Thom S, Ebrahim S, Whittaker JC, Smeeth L, Lawlor DA, Humphries SE, Hingorani AD (2010). Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.. Atherosclerosis, 213(1), 184 - 190. doi:10.1016/j.atherosclerosis.2010.07.021
    • Smith AJ, Palmen J, Putt W, Talmud PJ, Humphries SE, Drenos F (2010). Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.. Hum Mol Genet, 19(20), 3936 - 3947. doi:10.1093/hmg/ddq308
    • Humphries SE, Drenos F, Ken-Dror G, Talmud PJ (2010). Coronary heart disease risk prediction in the era of genome-wide association studies: current status and what the future holds.. Circulation, 121(20), 2235 - 2248. doi:10.1161/CIRCULATIONAHA.109.914192
    • Casas JP, Ninio E, Panayiotou A, Palmen J, Cooper JA, Ricketts SL, Sofat R, Nicolaides AN, Corsetti JP, Fowkes FG, Tzoulaki I, Kumari M, Brunner EJ, Kivimaki M, Marmot MG, Hoffmann MM, Winkler K, März W, Ye S, Stirnadel HA, Boekholdt SM, Khaw KT, Humphries SE, Sandhu MS, Hingorani AD, Talmud PJ (2010). PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.. Circulation, 121(21), 2284 - 2293. doi:10.1161/CIRCULATIONAHA.109.923383
    • Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration , Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, Saleheen D, Lawlor D, Reilly MP, Hingorani AD, Talmud PJ, Danesh J (2010). Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.. Lancet, 375(9726), 1634 - 1639. doi:10.1016/S0140-6736(10)60545-4
    • Salpea KD, Talmud PJ, Cooper JA, Maubaret CG, Stephens JW, Abelak K, Humphries SE (2010). Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variation.. Atherosclerosis, 209(1), 42 - 50. doi:10.1016/j.atherosclerosis.2009.09.070
    • Caplin B, Nitsch D, Gill H, Hoefield R, Blackwell S, MacKenzie D, Cooper JA, Middleton RJ, Talmud PJ, Veitch P, Norman J, Wheeler DC, Leiper JM (2010). Circulating methylarginine levels and the decline in renal function in patients with chronic kidney disease are modulated by DDAH1 polymorphisms.. Kidney Int, 77(5), 459 - 467. doi:10.1038/ki.2009.463
    • Sofat R, Hingorani AD, Smeeth L, Humphries SE, Talmud PJ, Cooper J, Shah T, Sandhu MS, Ricketts SL, Boekholdt SM, Wareham N, Khaw KT, Kumari M, Kivimaki M, Marmot M, Asselbergs FW, van der Harst P, Dullaart RP, Navis G, van Veldhuisen DJ, Van Gilst WH, Thompson JF, McCaskie P, Palmer LJ, Arca M, Quagliarini F, Gaudio C, Cambien F, Nicaud V, Poirer O, Gudnason V, Isaacs A, Witteman JC, van Duijn CM, Pencina M, Vasan RS, D'Agostino RB, Ordovas J, Li TY, Kakko S, Kauma H, Savolainen MJ, Kesaniemi YA, Sandhofer A, Paulweber B, Sorli JV, Goto A, Yokoyama S, Okumura K, Horne BD, Packard C, Freeman D, Ford I, Sattar N, McCormack V, Lawlor DA, Ebrahim S, Smith GD, Kastelein JJ, Deanfield J, Casas JP (2010). Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation, 121, 52 - 62.
    • Tsimikas S, Mallat Z, Talmud PJ, Kastelein JJ, Wareham NJ, Sandhu MS, Miller ER, Benessiano J, Tedgui A, Witztum JL, Khaw KT, Boekholdt SM (2010). Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events.. J Am Coll Cardiol, 56(12), 946 - 955. doi:10.1016/j.jacc.2010.04.048
    • Ken-Dror G, Talmud PJ, Humphries SE, Drenos F (2010). APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men.. Mol Med, 16(9-10), 389 - 399. doi:10.2119/molmed.2010.00044
    • Thompson A, Gao P, Orfei L, Watson S, Di AE, Kaptoge S, Ballantyne C, Cannon CP, Criqui M, Cushman M, Hofman A, Packard C, Thompson SG, Collins R, Danesh J (2010). Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet, 375(9725), 1536 - 1544.
    • Berardini TZ, Li DH, Huala E, Bridges S, Burgess S, McCarthy F, Carbon S, Lewis SE, Mungall CJ, Abdulla A, Wood V, Feltrin E, Valle G, Chisholm RL, Fey P, Gaudet P, Kibbe W, Basu S, Bushmanova Y, Eilbeck K, Siegele DA, McIntosh B, Renfro D, Zweifel A, Hu JC, Ashburner M, Tweedie S, Alam-Faruque Y, Apweiler R, Auchinchloss A, Bairoch A, Barrell D, Binns D, Blatter MC, Bougueleret L, Boutet E, Breuza L, Bridge A, Browne P, Chan WM, Coudert E, Daugherty L, Dimmer E, Eberhardt R, Estreicher A, Famiglietti L, Ferro-Rojas S, Feuermann M, Foulger R, Gruaz-Gumowski N, Hinz U, Huntley R, Jimenez S, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, O'Donovan C, Pedruzzi I, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Stanley E, Stutz A, Sundaram S, Tognolli M, Xenarios I, Harris MA, Deegan JI, Ireland A, Lomax J, Jaiswal P, Chibucos M, Giglio MG, Wortman J, Hannick L, Madupu R, Botstein D, Dolinski K, Livstone MS, Oughtred R, Blake JA, Bult C, Diehl AD, Dolan M, Drabkin H, Eppig JT, Hill DP, Ni L, Ringwald M, Sitnikov D, Collmer C, Torto-Alalibo T, Laulederkind S, Shimoyama M, Twigger S, D'Eustachio P, Matthews L, Balakrishnan R, Binkley G, Cherry JM, Christie KR, Costanzo MC, Engel SR, Fisk DG, Hirschman JE, Hitz BC, Hong EL, Krieger CJ, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng SA, Wong ED, Aslett M, Chan J, Kishore R, Sternberg P, Van Auken K, Khodiyar VK, Lovering RC, Talmud PJ, Howe D, Westerfield M, Gene Ontology Consortium (2010). The Gene Ontology in 2010: extensions and refinements The Gene Ontology Consortium. NUCLEIC ACIDS RES, 38, D331 - D335. doi:10.1093/nar/gkp1018

    2009

    • Ntalla I, Dedoussis G, Yannakoulia M, Smart MC, Louizou E, Sakka SD, Papoutsakis C, Talmud PJ (2009). ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity. Eur.J Nutr., 48(8), 493 - 497.
    • Rana JS, Arsenault BJ, Despres JP, Cote M, Talmud PJ, Ninio E, Jukema JW, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM (2009). Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women. Eur.Heart J, , - .
    • Smith AJP, Drenos F, Palmen J, Putt W, Talmud PJ, Humphries SE (2009). FUNCTIONAL ANALYSIS OF REGULATORY LPL SNPS. doi:10.1016/j.atherosclerosis.2009.09.037
    • Smart MC, Ehnholm C, Jauhiainen M, Robciuc M, Cooper JA, Drenos F, Humphries SE, Talmud PJ (2009). ASSOCIATION OF TELOMERE LENGTH WITH TYPE 2 DIABETES, OXIDATIVE STRESS AND UCP2 GENE VARIATION. doi:10.1016/j.atherosclerosis.2009.09.043
    • Smart MC, Ehnholm C, Jauhiainen M, Robciuc M, Cooper JA, Drenos F, Humphries SE, Talmud PJ (2009). ANGPTL4 E40K AND T266M: EFFECTS ON PLASMA TRIGLYCERIDE AND HDL LEVELS, ANGPTL4 LEVELS AND CHD RISK. doi:10.1016/j.atherosclerosis.2009.09.044
    • Guardiola M, Ken-Dror G, Humphries SE, Talmud PJ (2009). LRP5 VARIANTS ARE ASSOCIATED WITH TRIGLYCERIDE LEVELS AND TYPE 2 DIABETES. doi:10.1016/j.atherosclerosis.2009.09.049
    • Salpea KD, Cooper JA, Talmud PJ, Humphries SE (2009). ANGPTL3 VARIATION IN TYPE 2 DIABETES. doi:10.1016/j.atherosclerosis.2009.09.065
    • Drenos F, Talmud PJ, Casas JP, Smeeth L, Palmen J, Humphries SE, Hingorani AD (2009). Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. HUM MOL GENET, 18(12), 2305 - 2316. doi:10.1093/hmg/ddp159
    • Hingorani AD, Shah T, Casas JP, Humphries SE, Talmud PJ (2009). C-reactive protein and coronary heart disease: predictive test or therapeutic target?. Clin Chem, 55(2), 239 - 255. doi:10.1373/clinchem.2008.115923
    • Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. American Journal of Human Genetics, 85, 628 - 642.
    • Humphries S, Talmud P, Drenos F, Shah S, Palmen J, Shah T, Kumari M, Pallas J, Casas J, Whittaker J, Hingorani A (2009). GENETIC DETERMINANTS OF LDL-C LEVELS: USING THE 50K CARDIO-METABOLIC CHIP TO EXPLORE THE GENETIC ARCHITECTURE OF LIPID TRAITS IN WHITEHALL II. ATHEROSCLEROSIS SUPP, 10(2), - .
    • Humphries S, Drenos F, Casas J, Palmen J, Smeeth L, Hingorani A, Talmud P (2009). INTEGRATED ASSOCIATIONS OF GENOTYPES WITH MULTIPLE BLOOD BIOMARKERS LINKED TO CORONARY HEART DISEASE RISK. ATHEROSCLEROSIS SUPP, 10(2), - .
    • Salpea K, Talmud P, Cooper J, Abelak K, Stephens J, Humphries S (2009). TELOMERE LENGTH IS ASSOCIATED WITH OXIDATIVE STRESS AND UCP2 GENE VARIATION IN TYPE 2 DIABETES PATIENTS. ATHEROSCLEROSIS SUPP, 10(2), - .
    • Rana JS, Cote M, Despres JP, Sandhu MS, Talmud PJ, Ninio E, Wareham NJ, Kastelein JJ, Zwinderman AH, Khaw KT, Boekholdt SM (2009). Inflammatory biomarkers and the prediction of coronary events among people at intermediate risk: the EPIC-Norfolk prospective population study. Heart, 95(20), 1682 - 1687.
    • Lovering RC, Dimmer EC, Talmud PJ (2009). Improvements to cardiovascular gene ontology.. Atherosclerosis, 205(1), 9 - 14. doi:10.1016/j.atherosclerosis.2008.10.014
    • Laatsch A, Merkel M, Talmud PJ, Grewal T, Beisiegel U, Heeren J (2009). Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance. Athero, 204(1), 105 - 111.
    • Kotronen A, Yki-Jarvinen H, Aminoff A, Bergholm R, Pietilainen KH, Westerbacka J, Talmud PJ, Humphries SE, Hamsten A, Isomaa B, Groop L, Orho-Melander M, Ehrenborg E, Fisher RM (2009). Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts. Eur.J Endocrinol., 160(4), 593 - 602.
    • Shah S, Drenos F, Shah T, Palmen J, Vezzili C, Sofat R, Kumari M, Kivamaki M, Pallas J, MacFarlane P, Whittaker J, Talmud PJ, Humphries SE, Hingorani AD (2009). IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY. doi:10.1016/j.atherosclerosis.2009.09.058

    2008

    • Dorfmeister B, Zeng WW, Dichlberger A, Nilsson SK, Schaap FG, Hubacek JA, Merkel M, Cooper JA, Lookene A, Putt W, Whittall R, Lee PJ, Lins L, Delsaux N, Nierman M, Kuivenhoven JA, Kastelein JJ, Vrablik M, Olivecrona G, Schneider WJ, Heeren J, Humphries SE, Talmud PJ (2008). Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding.. Arterioscler Thromb Vasc Biol, 28(10), 1866 - 1871. doi:10.1161/ATVBAHA.108.172866
    • Gable D, Pierce B, Talmud P, Lee K, Humphries S, Austin M (2008). Variation in the transcription factor 7-like 2(TCF7L2) does not play a significant role in conferring type 2 diabetes risk in Japanese Americans. DIABETOLOGIA, 51, S124 - S125.
    • Dimmer EC, Huntley RP, Barrell DG, Binns D, Draghici S, Camon EB, Hubank M, Talmud PJ, Apweiler R, Lovering RC (2008). The Gene Ontology - Providing a Functional Role in Proteomic Studies. Proteomics, , - .
    • Palmen J, Smith AJ, Dorfmeister B, Putt W, Humphries SE, Talmud PJ (2008). The functional interaction on in vitro gene expression of APOA5 SNPs, defining haplotype APOA52, and their paradoxical association with plasma triglyceride but not plasma apoAV levels.. Biochim Biophys Acta, 1782(7-8), 447 - 452. doi:10.1016/j.bbadis.2008.03.003
    • Salpea KD, Nicaud V, Tiret L, Talmud PJ, Humphries SE, EARS II group (2008). The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study II.. J Mol Med (Berl), 86(7), 815 - 824. doi:10.1007/s00109-008-0347-x
    • Hubacek JA, Wang WW, Skodová Z, Adámková V, Vráblík M, Horínek A, Stulc T, Ceska R, Talmud PJ (2008). APOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levels.. Clin Chem Lab Med, 46(6), 773 - 777. doi:10.1515/CCLM.2008.160
    • Humphries SE, Yiannakouris N, Talmud PJ (2008). Cardiovascular disease risk prediction using genetic information (gene scores): is it really informative?. Curr Opin Lipidol, 19(2), 128 - 132. doi:10.1097/MOL.0b013e3282f5283e
    • Witsch-Baumgartner M, Schwentner I, Gruber M, Benlian P, Bertranpetit J, Bieth E, Chevy F, Clusellas N, Estivill X, Gasparini G, Giros M, Kelley RI, Krajewska-Walasek M, Menzel J, Miettinen T, Ogorelkova M, Rossi M, Scala I, Schinzel A, Schmidt K, Schönitzer D, Seemanova E, Sperling K, Syrrou M, Talmud PJ, Wollnik B, Krawczak M, Labuda D, Utermann G (2008). Age and origin of major Smith-Lemli-Opitz syndrome (SLOS) mutations in European populations.. J Med Genet, 45(4), 200 - 209. doi:10.1136/jmg.2007.053520
    • Talmud PJ, Cooper JA, Palmen J, Lovering R, Drenos F, Hingorani AD, Humphries SE (2008). Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men.. Clin Chem, 54(3), 467 - 474. doi:10.1373/clinchem.2007.095489
    • Talmud PJ, Smart M, Presswood E, Cooper JA, Nicaud V, Drenos F, Palmen J, Marmot MG, Khaw KT, Kumari M, Humphries SEOBOTEARSIICATHIFMECHC (2008). ANGPTL4 E40K and T266M: effects on plasma Triglyceride and HDL levels, postprandial responses and CHD risk. Arteriosclerosis, Thrombosis, and Vascular Biology, , - .
    • Lovering RC, Dimmer E, Khodiyar VK, Barrell DG, Scambler P, Hubank M, Apweiler R, Talmud PJ (2008). Cardiovascular GO annotation initiative year 1 report: why cardiovascular GO?. Proteomics, 8(10), 1950 - 1953.

    2007

    • Wootton PTE, Arora NL, Drenos F, Thompson SR, Cooper JA, Stephens JW, Hurel SJ, Hurt-Camejo E, Wiklund O, Humphries SE, Talmud PJ (2007). Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study. HUM MOL GENET, 16(12), 1437 - 1444. doi:10.1093/hmg/ddm094
    • Talmud PJ, Flavell DM, Alfakih K, Cooper JA, Balmforth AJ, Sivananthan M, Montgomery HE, Hall AS, Humphries SE (2007). The lipoprotein lipase gene serine 447 stop variant influences hypertension-induced left ventricular hypertrophy and risk of coronary heart disease.. Clin Sci (Lond), 112(12), 617 - 624. doi:10.1042/CS20060344
    • Dorfmeister B, Cooper JA, Stephens JW, Ireland H, Hurel SJ, Humphries SE, Talmud PJ (2007). The effect of APOA5 and APOC3 variants on lipid parameters in European Whites, Indian Asians and Afro-Caribbeans with type 2 diabetes. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1772(3), 355 - 363. doi:10.1016/j.bbadis.2006.11.008
    • Humphries SE, Cooper JA, Talmud PJ, Miller GJ (2007). Candidate gene genotypes, along with conventional risk factor assessment, improve estimation of coronary heart disease risk in healthy UK men.. Clinical Chemistry, Jan; 53(1), 8 - 16.
    • van der Vleuten GM, Isaacs A, Zeng WW, ter Avest E, Talmud PJ, Dallinga-Thie GM, van Duijn CM, Stalenhoef AFH, de Graaf J (2007). Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia. BBA-MOL BASIS DIS, 1772(1), 81 - 88. doi:10.1016/j.bbadis.2006.10.012
    • Talmud PJ (2007). Rare APOA5 mutations--clinical consequences, metabolic and functional effects: an ENID review.. Atherosclerosis, 194(2), 287 - 292. doi:10.1016/j.atherosclerosis.2006.12.010
    • Ballantyne C, Cushman M, Psaty B, Furberg C, Khaw KT, Sandhu M, Oldgren J, Rossi GP, Maiolino G, Cesari M, Lenzini L, James SK, Rimm E, Collins R, Anderson J, Koenig W, Brenner H, Rothenbacher D, Berglund G, Persson M, Berger P, Brilakis E, McConnell JP, Koenig W, Sacco R, Elkind M, Talmud P, Rimm E, Cannon CP, Packard C, Cannon CP, Barrett-Connor E, Hofman A, Kardys I, Witteman JCM, Criqui M, Corsetti JP, Rainwater DL, Moss AJ, Robins S, Bloomfield H, Collins D, Packard C, Ridker P, Ballantyne C, Cannon CP, Collins R, Criqui M, Cushman M, Danesh J, Gu D, Hofman A, Nelson JJ, Packard C, Thompson S, Zalewski A, Danesh J, Collins R, Di Angelantonio E, Kaptoge S, Thompson A, Thompson S, Watson S, Wood A, Lp-PLA2 Studies Collaboration (2007). Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA(2) and cardiovascular diseases. EUR J CARDIOV PREV R, 14(1), 3 - 11.
    • Talmud PJ (2007). Gene-environment interaction and its impact on coronary heart disease risk.. Nutr Metab Cardiovasc Dis, 17(2), 148 - 152. doi:10.1016/j.numecd.2006.01.008
    • Wootton PT, Flavell DM, Montgomery HE, World M, Humphries SE, Talmud PJ (2007). Lipoprotein-associated phospholipase A2 A379V variant is associated with body composition changes in response to exercise training.. Nutr Metab Cardiovasc Dis, 17(1), 24 - 31. doi:10.1016/j.numecd.2005.11.008

    2006

    • Wootton PT, Stephens JW, Hurel SJ, Durand H, Cooper J, Ninio E, Humphries SE, Talmud PJ (2006). Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus.. Atherosclerosis, 189(1), 149 - 156. doi:10.1016/j.atherosclerosis.2005.12.009
    • Talmud PJ, Cooper JA, Hattori H, Miller IP, Miller GJ, Humphries SE (2006). The apolipoprotein A-V genotype and plasma apolipoprotein A-V and triglyceride levels: prospective risk of type 2 diabetes. Results from the Northwick Park Heart Study II.. Diabetologia, 49(10), 2337 - 2340.
    • Vaessen SF, Schaap FG, Kuivenhoven JA, Groen AK, Hutten BA, Boekholdt SM, Hattori H, Sandhu MS, Bingham SA, Luben R, Palmen JA, Wareham NJ, Humphries SE, Kastelein JJ, Talmud PJ, Khaw KT (2006). Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.. The Journal of Lipid Research, 47(9), 2064 - 2070.
    • Barter PJ, Ballantyne CM, Carmena R, Castro Cabezas M, Chapman MJ, Couture P, de Graaf J, Durrington PN, Faergeman O, Frohlich J, Furberg CD, Gagne C, Haffner SM, Humphries SE, Jungner I, Krauss RM, Kwiterovich P, Marcovina S, Packard CJ, Pearson TA, Reddy KS, Rosenson R, Sarrafzadegan N, Sniderman AD, Stalenhoef AF, Stein E, Talmud PJ, Tonkin AM, Walldius G, Williams KM (2006). Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel.. Journal of Internal Medicine, 259(3), 247 - 258.
    • Flavell DM, Wootton PT, Myerson SG, World MJ, Pennell DJ, Humphries SE, Talmud PJ, Montgomery HE (2006). Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth.. Journal of Molecular Medicine, 84(2), 126 - 131.
    • van der Vleuten GM, Isaacs A, Zeng W, Talmud PH, van Duijn CM, Stalenhoef AFH, de Graaf J (2006). The apoAV gene is associated with familial combined hyperlipidemia and dyslipidemia.
    • Wootton PT, Drenos F, Cooper JA, Thompson SR, Stephens JW, Hurt-Camejo E, Wiklund O, Humphries SE, Talmud PJ (2006). Tagging-SNP haplotype analysis of the secretory PLA2IIa gene PLA2G2A shows strong association with serum levels of sPLA2IIa: results from the UDACS study.. Human Molecular Genetics, 15(2), 355 - 361.
    • Wong WM, Gerry AB, Putt W, Roberts JL, Weinberg RB, Humphries SE, Leake DS, Talmud PJ (2006). Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation.. Atherosclerosis, , - .
    • Humphries SE, Gable D, Cooper JA, Ireland H, Stephens JW, Hurel S, Li KW, Palmen J, Miller MA, Cappuccio FP, Elkeles R, Godsland I, Miller GJ, Talmud PJ (2006). Common variants in the TCF7L2 gene and predisposition to Type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and women.. Journal of Molecular Medicine, 84(12), 1005 - 1014.
    • Schaap FG, Nierman MC, Berbee JF, Hattori H, Talmud PJ, Vaessen SF, Rensen PC, Chamuleau RA, Kuivenhoven JA, Groen AK (2006). Evidence for a complex relationship between apoA-V and apoC-III in patients with severe hypertriglyceridemia.. The Journal of Lipid Research, 47(10), 2333 - 2339.
    • Wootton P, Drenos F, Cooper J, Thompson S, Stephens J, Hurt-Camejo E, Wiklund O, Humphries S, Talmud P (2006). Tagging SNP haplotype analysis of the secretory PLA2-IIA gene PLA2G2A shows strong association with serum levels of sPLA2IIa. Atherosclerosis Supplements, 7(3), 24 - 24.
    • Talmud PJ (2006). Pharmacogenetics and Heart disease - Introduction. VASC PHARMACOL, 44(2), 65 - 65. doi:10.1016/j.vph.2005.10.002

    2005

    • Talmud PJ, Stephens JW, Hawe E, Demissie S, Cupples LA, Hurel SJ, Humphries SE, Ordovas JM (2005). The significant increase in cardiovascular disease risk in APOEepsilon4 carriers is evident only in men who smoke: potential relationship between reduced antioxidant status and ApoE4.. Ann Hum Genet, 69(Pt 6), 613 - 622. doi:10.1111/j.1529-8817.2005.00205.x
    • Talmud P, Palmen J, Putt W, Lins L, Humphries SE (2005). Determination of the functionality of common APOA5 polmorphisms. Journal of Biological Chemistry, 280(31), 28215 - 28220. doi:10.1074/jbc.M502144200
    • Waterworth DM, Jansen H, Nicaud V, Humphries SE, Talmud PJOBOTEARSIIS, g ROUP (2005). Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1740(3), 375 - 381.
    • Talmud PJ, Palmen J, Wolf AM, Beisiegel U (2005). Investigation into the role of the hormone sensitive lipase -60C>G promoter variant in morbid obesity.. Nutr Metab Cardiovasc Dis, 15(1), 31 - 35. doi:10.1016/j.numecd.2004.11.001
    • Elrayess MA, Talmud PJ (2005). Platelet endothelial cell adhesion molecule-1 (PECAM-1) & coronary heart disease.. Indian Journal of Medical Research, 121(2), 77 - 79.
    • Boekholdt SM, Sacks FM, Jukema JW, Shepherd J, Freeman DJ, McMahon AD, Cambien F, Nicaud V, de Grooth GJ, Talmud PJ, Humphries SE, Miller GJ, Eiriksdottir G, Gudnason V, Kauma H, Kakko S, Savolainen MJ, Arca M, Montali A, Liu S, Lanz HJ, Zwinderman AH, Kuivenhoven JA, Kastelein JJ (2005). Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects.. Circulation, 111(3), 278 - 287.
    • Zhao JH, Brunner EJ, Kumari M, Singh-Manoux A, Hawe E, Talmud PJ, Marmot MG, Humphries SE (2005). APOE polymorphism, socioeconomic status and cognitive function in mid-life The Whitehall II longitudinal study.. Social Psychiatry and Psychiatric Epidemiology, 40(7), 557 - 563.
    • Younis J, Cooper JA, Miller GJ, Humphries SE, Talmud PJ (2005). Genetic variation in alcohol dehydrogenase 1C and the beneficial effect of alcohol intake on coronary heart disease risk in the Second Northwick Park Heart Study.. Atherosclerosis, 180(2), 225 - 232.

    2004

    • Foucher C, Rattier S, Flavell DM, Talmud PJ, Humphries SE, Kastelein JJ, Ayyobi A, Pimstone S, Frohlich J, Ansquer JC, Steiner G DAIS INVESTIGATORS (2004). Response to micronized fenofibrate treatment is associated with the peroxisome-proliferator-activated receptors alpha G/C intron7 polymorphism in subjects with type 2 diabetes.. Pharmacogenetics, 14(12), 823 - 829.
    • Talmud PJ, Lewis SJ, Hawe E, Martin S, Acharya J, Marmot MG, Humphries SE, Brunner EJ (2004). No APOE epsilon 4 effect on coronary heart disease risk in a cohort with low smoking prevalence: the Whitehall II study. ATHEROSCLEROSIS, 177(1), 105 - 112. doi:10.1016/j.athersclerosis.2004.06.008
    • Putt W, Palmen J, Nicaud V, Tregouet DA, Tahri-Daizadeh N, Flavell DM, Humphries SE, Talmud PJ, EARSII GROUP (2004). Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II.. Human Molecular Genetics, 13(15), 1587 - 1597. doi:10.1093/hmg/ddh168
    • Wong WMR, Stephens JW, Acharya J, Hurel SJ, Humphries SE, Talmud PJ (2004). The APOA4 T347S variant is associated with reduced plasma TAOS in subjects with diabetes mellitus and cardiovascular disease. J LIPID RES, 45(8), 1565 - 1571. doi:10.1194/jlr.M400130
    • Austin MA, Zhang C, Humphries SE, Chandler WL, Talmud PJ, Edwards KL, Leonetti DL, McNeely MJ, Fujimoto WY (2004). Heritability of C-reactive protein and association with apolipoprotein E genotypes in Japanese Americans.. Annals of Human Genetics, 68(3), 179 - 188.
    • Austin MA, Edwards KL, McNeely MJ, Chandler WL, Leonetti DL, Talmud PJ, Humphries SE, Fujimoto WY (2004). Heritability of multivariate factors of the metabolic syndrome in nondiabetic Japanese americans.. Diabetes, 53(4), 1166 - 1169.
    • Humphries SE, Ridker PM, Talmud PJ (2004). Genetic testing for cardiovascular disease susceptibility: a useful clinical management tool or possible misinformation?. Arteriosclerosis, Thrombosis, and Vascular Biology, 24(4), 628 - 636.
    • Talmud PJ, Martin S, Taskinen MR, Frick MH, Nieminen MS, Kesaniemi YA, Pasternack A, Humphries SE, Syvanne M (2004). APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study.. The Journal of Lipid Research, 45(4), 750 - 756.
    • Talmud PJ (2004). How to identify gene-environment interactions in a multifactorial disease: CHD as an example.. Proceedings of the Nutrition Society, 63(1), 5 - 10.
    • Austin MA, Talmud PJ, Farin FM, Nickerson DA, Edwards KL, Leonetti D, McNeely MJ, Viernes HM, Humphries SE, Fujimoto WY (2004). Association of apolipoprotein A5 variants with LDL particle size and triglyceride in Japanese Americans.. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1688(1), 1 - 9.
    • Talmud PJ, Stephens JW (2004). Lipoprotein lipase gene variants and the effect of environmental factors on cardiovascular disease risk.. Diabetes, Obesity and Metabolism, 6(1), 1 - 7.
    • Talmud PJ, Humphries SE (2004). Gene: environment interactions and coronary heart disease risk.. World Review of Nutrition and Dietetics, 93, 29 - 40.
    • Talmud PJ, Hawe E, Miller GJ, Humphries SE (2004). Are plasma triglycerides a good predictor of CHD risk.. International Congress Series, 1262, 207 - 210.
    • Chen XH, Rodriguez S, Hawe E, Talmud PJ, Miller GJ, Underhill P, Humphries SE, Day INM (2004). Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: Implications for association analyses. HUM HERED, 57(3), 142 - 155. doi:10.1159/000079245

    2003

    • Robertson KS, Hawe E, Miller GJ, Talmud PJ, Humphries SE (2003). Human paraoxonase gene cluster polymorphisms as predictors of coronary heart disease risk in the prospective Northwick Park Heart Study II. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1639(3), 203 - 212. doi:10.1016/j.bbadis.2003.09.008
    • Talmud PJ, Martin S, Nagl S, Steiner G, et A (2003). Progression of atherosclerosis is associated with variation in the œ1- antitrypsin gene. Arteriosclerosis, Thrombosis, and Vascular Biology, 23(644), 649 - .
    • Fisher RM, Benhizia F, Schreiber R, Makoveichuk E, Putt W, Al Haideri M, Deckelbaum RJ, Olivecrona G, Humphries SE, Talmud PJ (2003). Enhanced bridging function and augmented monocyte adhesion by lipoprotein lipase N9: insights into increased risk of coronary artery disease in N9 carriers. Atherosclerosis, 166(2), 243 - 251.
    • Hawe E, Talmud PJ, Miller GJ, Humphries SE (2003). Family history is a coronary heart disease risk factor in the Second Northwick Park Heart Study. Annals of Human Genetics, 67(Pt 2), 97 - 106.
    • Talmud PJ, Martin S, Steiner G, Flavell DM, Whitehouse DB, Nagl S, Jackson R, Taskinen MR, Frick MH, Nieminen MS, Kesaniemi YA, Pasternack A, Humphries SE, Syvanne M (2003). Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene. Arteriosclerosis, Thrombosis, and Vascular Biology, 23(4), 644 - 649.
    • Waterworth DM, Talmud PJ, Luan J, Flavell DM, Byrne CD, Humphries SE, Wareham NJ (2003). Variants in the APOC3 promoter insulin responsive element modulate insulin secretion and lipids in middle-aged men. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1637(3), 200 - 206. doi:10.1016/S0925-4439(03)00021-8
    • Talmud PJ, Wright R, Steiner G, Syvanne M, Humphries SE (2003). Risk of ischemic heart and ischemic cerebrovascular disease is not increased in S, Z, and 11478A alpha(1)-antitrypsin - Carriers of the Copenhagen City Heart Study - Response. ARTERIOSCL THROM VAS, 23(11), - .
    • Wong WM, Hawe E, Li LK, Miller GJ, Nicaud V, Pennacchio LA, Humphries SE, Talmud PJ (2003). Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels. Circulation Research, 92(9), 969 - 975. doi:10.1161/01.RES.0000069688.94567.7A
    • Humphries SE, Hawe E, Dhamrait S, Miller GJ, Talmud PJ (2003). In search of genetic precision. The Lancet, 361(9372), 1908 - 1909.
    • Hubacek JA, Pitha J, Skodova Z, Poledne R, Lanska V, Waterworth DM, Humphries SE, Talmud PJ (2003). Polymorphisms in CYP-7A1, not APOE, influence the change in plasma lipids in response to population dietary change in an 8 year follow-up; results from the Czech MONICA study. Clinical Biochemistry, 36(4), 263 - 267.
    • Abuzeid AM, Hawe E, Humphries SE, Talmud PJ (2003). Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe. Atherosclerosis, 168(2), 283 - 288.
    • Talmud PJ, Hawe E, Miller GJ, Humphries SE (2003). Genetic determinants of plasma triglycerides and CHD risk.
    • Martin S, Nicaud V, Humphries SE, Talmud PJ (2003). Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1637(3), 217 - 225. doi:10.1016/S0925-4439(03)00033-4

    2002

    • Talmud P, Hawe E, Martin S, Olivier M, Miller GJ, Rubin EM, Pennacchio LA, Humphries SE (2002). Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Human Molecular Genetics, 11(24), 3039 - 3046. doi:10.1093/hmg/11.24.3039
    • Talmud PJ, Hawe E, Miller GJ (2002). Analysis of gene-environment interaction in coronary artery disease: lipoprotein lipase and smoking as examples. Italian Heart Journal, 3(1), 6 - 9.
    • Khan S, Minihane AM, Talmud PJ, Wright JW, Murphy MC, Williams CM, Griffin BA (2002). Dietary long-chain n-3 PUFAs increase LPL gene expression in adipose tissue of subjects with an atherogenic lipoprotein phenotype. J LIPID RES, 43(6), 979 - 985.
    • Lins L, Flore C, Chapelle L, Talmud PJ, Thomas A, Brasseur R (2002). Lipid-interacting properties of the N-terminal domain of human apolipoprotein C-III. Protein Engineering, 15(6), 513 - 520.
    • Khan S, Minihane AM, Talmud PJ, Wright JW, Murphy MC, Williams CM, Griffin BA (2002). Dietary long-chain n-3 PUFAs increase LPL gene expression in adipose tissue of subjects with an atherogenic lipoprotein phenotype. The Journal of Lipid Research, 43(6), 979 - 985.
    • Talmud PJ, Humphries SE (2002). Gene:environment interaction in lipid metabolism and effect on coronary heart disease risk. Current Opinion in Lipidology, 13(2), 149 - 154.
    • Flavell DM, Jamshidi Y, Hawe E, Pineda T, I T, M R F, M H N, M S K, Y A P, A S, B M, G H, S E T, P J S, M (2002). Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease. Circulation, 105(12), 1440 - 1445.
    • Talmud PJ, Hawe E, Robertson K, Miller GJ, Miller NE, Humphries SE (2002). Genetic and environmental determinants of plasma high density lipoprotein cholesterol and apolipoprotein AI concentrations in healthy middle-aged men. Annals of Human Genetics, 66(Pt 2), 111 - 124.
    • Sniderman AD, Castro CM, Ribalta J, Carmena R, de Bruin TW, de Graaf J, Erkelens DW, Humphries SE, Masana L, Real JT, Talmud PJ, Taskinen MR (2002). A proposal to redefine familial combined hyperlipidaemia -- third workshop on FCHL held in Barcelona from 3 to 5 May 2001, during the scientific sessions of the European Society for Clinical Investigation. European Journal of Clinical Investigation, 32(2), 71 - 73.
    • Talmud PJ, Hawe E, Miller GJ, Humphries SE (2002). Nonfasting apolipoprotein B and triglyceride levels as a useful predictor of coronary heart disease risk in middle-aged UK men. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(11), 1918 - 1923.
    • Minihane AM, Finnegan YE, Talmud P, Leigh-Firbank EC, Williams CM (2002). Influence of the APOC3 -2854T>G polymorphism on plasma lipid levels: effect of age and gender. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1583(3), 311 - 314.
    • Flavell D, Wootton P, Montgomery H, Humphries SE, Talmud PJ (2002). Lipoprotein lipase genotype influences exercise-induced cardiac growth.
    • Talmud PJ, Palmen J, Nicaud V, Tiret L, European Atherosclerosis Research II Study (2002). Association of the hormone sensitive lipase -60C > G variant with fasting insulin levels in healthy young men.. Nutr Metab Cardiovasc Dis, 12(4), 173 - 177.
    • Humphries SE, Berglund L, Isasi CR, Otvos JD, Kaluski D, Deckelbaum RJ, Shea S, Talmud PJ (2002). Loci for CETP, LPL, LIPC, and APOC3 affect plasma lipoprotein size and sub-population distribution in Hispanic and non-Hispanic white subjects: the Columbia University BioMarkers Study. Nutrition, Metabolism and Cardiovascular Diseases, 12(4), 163 - 172.

    2001

    • Edwards KL, Talmud PJ, Newman B, Krauss RM, Austin MA (2001). Lipoprotein candidate genes for multivariate factors of the insulin resistance syndrome: a sib-pair linkage analysis in women twins. Twin Research, 4(1), 41 - 47.
    • Talmud PJ (2001). Genetic determinants of plasma triglycerides: impact of rare and common mutations. Current Atherosclerosis Reports, 3(3), 191 - 199.
    • Jansen H, Waterworth DM, Nicaud V, Ehnholm C, Talmud PJ (2001). Interaction of the common apolipoprotein C-III (APOC3 -482C > T) and hepatic lipase (LIPC -514C > T) promoter variants affects glucose tolerance in young adults. European Atherosclerosis Research Study II (EARS-II). Annals of Human Genetics, 65(Pt 3), 237 - 243.
    • Talmud PJ, Palmen J, Luan J, Flavell D, Byrne CD, Waterworth DM, Wareham NJ (2001). Variation in the promoter of the human hormone sensitive lipase gene shows gender specific effects on insulin and lipid levels: results from the Ely study.. Biochim Biophys Acta, 1537(3), 239 - 244.
    • Boren J, Lookene A, Makoveichuk E, Xiang S, Gustafsson M, Liu H, Talmud P, Olivecrona G (2001). Binding of low density lipoproteins to lipoprotein lipase is dependent on lipids but not on apolipoprotein B. Journal of Biological Chemistry, 276(29), 26916 - 26922.
    • Talmud PJ, Waterworth DM, Humphries SE (2001). Effect of genetic variation on the postprandial response. Results from the European Atherosclerosis Research Study II. WORLD REVIEW OF NUTRITION AND DIET, 89, 53 - 60.
    • Humphries SE, Montgomery HE, Talmud PJ (2001). Predisposing genes, high-risk environments and coronary artery disease: LPL and fibrinogen as examples. WORLD REVIEW OF NUTRITION AND DIET, 89, 61 - 67.
    • Hubacek JA, Waterworth DM, Pitha J, Humphries SE, Talmud PJ, Poledne R (2001). Polymorphisms in the lipoprotein lipase and hepatic lipase genes and plasma lipid values in the Czech population. PHYSIOLOGICAL RESEARCH, 50(4), 345 - 351.
    • Waterworth DM, Talmud PJ, Humphries SE, Wicks PD, Sagnella GA, Strazzullo P, Alberti KG, Cook DG, Cappuccio FP (2001). Variable effects of the APOC3-482C > T variant on insulin, glucose and triglyceride concentrations in different ethnic groups. Diabetologia, 44(2), 245 - 248.
    • Hubacek JA, Waterworth DM, Poledne R, Pitha J, Skodova Z, Humphries SE, Talmud PJ (2001). Genetic determination of plasma lipids and insulin in the Czech population. Clinical Biochemistry, 34(2), 113 - 118.
    • Edwards KL, Monks SA, LeBoeuf R, Leonetti D, Talmud PJ, Humphries S, Austin MA, Fujimoto WY (2001). Common genetic influences on fasting insulin and waist circumference: The Japanese American Family Study. CIRCULATION, 103(9), 1353 - 1353.
    • Benhizia F, Ginsberg HN, Humphries SE, Talmud PJ (2001). Variation in the human ApoB signal peptide modulates ApoB17 translocation. Biochemical and Biophysical Research Communications, 283(1), 149 - 157.
    • Humphries SE, Talmud PJ, Hawe E, Bolla M, Day IN, Miller GJ (2001). Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study. The Lancet, 358(9276), 115 - 119. doi:10.1016/S0140-6736(01)05330-2
    • Talmud PJ, Humphries SE (2001). Genetic polymorphisms, lipoproteins and coronary artery disease risk. CURRENT OPINIONS IN LIPIDOLOGY, 12(4), 405 - 409.
    • Flavell D, Talmud PJ, Day INM, Miller G, Humphries SE (2001). Gene : environment interactions in determination of risk of coronary artery disease. J MED GENET, 38, S12 - S12.
    • Talmud PJ, Berglund L, Hawe EM, Waterworth DM, Isasi CR, Deckelbaum RE, Starc T, Ginsberg HN, Humphries SE, Shea S (2001). Age-related effects of genetic variation on lipid levels: The Columbia University BioMarkers Study. Pediatrics, 108(3), E50 - .

    2000

    • Flavell DM, Pineda T, I J, Y E, D D, J R E, R S B, S R M, G T, P J S, B H, S E (2000). Variation in the PPARalpha gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects. Diabetologia, 43(5), 673 - 680.
    • Hall S, Talmud PJ, Cook DG, Wicks PD, Rothwell MJ, Strazzullo P, Sagnella GA, Cappuccio FP (2000). Frequency and allelic association of common variants in the lipoprotein lipase gene in different ethnic groups: the Wandsworth Heart and Stroke Study. Genetic Epidemiology, 18(3), 203 - 216.
    • Watts GF, Riches FM, Humphries SE, Talmud PJ, van Bockxmeer FM (2000). Genotypic associations of the hepatic secretion of VLDL apolipoprotein B-100 in obesity. The Journal of Lipid Research, 41(3), 481 - 488.
    • Waterworth DM, Talmud PJ, Bujac SR, Fisher RM, Miller GJ, Humphries SE (2000). Contribution of apolipoprotein C-III gene variants to determination of triglyceride levels and interaction with smoking in middle-aged men. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(12), 2663 - 2669.
    • Talmud PJ, Edwards KL, Turner CM, Newman B, Palmen JM, Humphries SE, Austin MA (2000). Linkage of the cholesteryl ester transfer protein (CETP) gene to LDL particle size: use of a novel tetranucleotide repeat within the CETP promoter. Circulation, 101(21), 2461 - 2466.
    • Waterworth DM, Hubacek JA, Pitha J, Kovar J, Poledne R, Humphries SE, Talmud PJ (2000). Plasma levels of remnant particles are determined in part by variation in the APOC3 gene insulin response element and the APOCI-APOE cluster. The Journal of Lipid Research, 41(7), 1103 - 1109.
    • Talmud PJ, Palmen J, Miller G, Humphries SE (2000). Effect of microsomal triglyceride transfer protein gene variants (-493G > T, Q95H and H297Q) on plasma lipid levels in healthy middle-aged UK men. Annals of Human Genetics, 64(Pt 4), 269 - 276.
    • Friedlander Y, Talmud PJ, Edwards KL, Humphries SE, Austin MA (2000). Sib-pair linkage analysis of longitudinal changes in lipoprotein risk factors and lipase genes in women twins. The Journal of Lipid Research, 41(8), 1302 - 1309.
    • Minihane AM, Khan S, Talmud PJ, Williams DL, Wright JW, Murphy MC, Griffin BA, Williams CM (2000). Lack of association between lipaemia and central adiposity in subjects with an atherogenic lipoprotein phenotype (ALP). International Journal of Obesity, 24(9), 1097 - 1106.
    • Talmud PJ, Waterworth DM (2000). Genetics and molecular biology. CURR OPIN LIPIDOL, 11(5), 555 - 556.
    • Wallace AJ, Mann JI, Sutherland WH, Williams S, Chisholm A, Skeaff CM, Gudnason V, Talmud PJ, Humphries SE (2000). Variants in the cholesterol ester transfer protein and lipoprotein lipase genes are predictors of plasma cholesterol response to dietary change. Atherosclerosis, 152(2), 327 - 336.
    • Liu H, Labeur C, Xu CF, Ferrell R, Lins L, Brasseur R, Rosseneu M, Weiss KM, Humphries SE, Talmud PJ (2000). Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr. The Journal of Lipid Research, 41(11), 1760 - 1771.
    • Talmud PJ, Waterworth DM (2000). In-vivo and in-vitro nutrient-gene interactions.. Curr Opin Lipidol, 11(1), 31 - 36.
    • Liu H, Talmud PJ, Lins L, Brasseur R, Olivecrona G, Peelman F, Vandekerckhove J, Rosseneu M, Labeur C (2000). Characterization of recombinant wild type and site-directed mutations of apolipoprotein C-III: lipid binding, displacement of ApoE, and inhibition of lipoprotein lipase. Biochemistry, 39(31), 9201 - 9212.
    • Minihane AM, Khan S, Leigh-Firbank EC, Talmud P, Wright JW, Murphy MC, Griffin BA, Williams CM (2000). ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(8), 1990 - 1997.
    • Talmud PJ, Bujac SR, Hall S, Miller GJ, Humphries SE (2000). Substitution of asparagine for aspartic acid at residue 9 (D9N) of lipoprotein lipase markedly augments risk of ischaemic heart disease in male smokers. Atherosclerosis, 149(1), 75 - 81.

    1999

    • Wallace AJ, Gudnason V, Mann JI, Sutherland WHF, Williams S, Chisholm A, Skeaff CM, Talmud PJ, Humphries SE (1999). Cholesterol ester transfer protein genotype is a determinant of variation in plasma cholesterol response to change in dietary fat intake. ATHEROSCLEROSIS, 145(2), 436 - 436.
    • Watts GF, Riches FM, Humphries SE, Talmud PJ, van Bockxmeer FM (1999). Role of microsomal triglyceride transfer protein, apoB signal peptide and apoe genes in determining the hepatic secretion of apolipoprotein B-100 in obesity. ATHEROSCLEROSIS, 144, 4 - 4.
    • Talmud PJ, Waterworth DM, Humphries SE (1999). The contribution of genetic variation to the postprandial response: Results from the European atherosclerosis research study (EARSII). ATHEROSCLEROSIS, 144, 81 - 81.
    • Waterworth DM, Ribalta J, Nicaud V, Dallongeville J, Humphries SE, Talmud P (1999). ApoCIII gene variants modulate postprandial response to both glucose and fat tolerance tests.. Circulation, 99(14), 1872 - 1877.
    • Montgomery H, Clarkson P, Barnard M, Bell J, Brynes A, Dollery C, Hajnal J, Hemingway H, Mercer D, Jarman P, Marshall R, Prasad K, Rayson M, Saeed N, Talmud P, Thomas L, Jubb M, World M, Humphries S (1999). Angiotensin-converting-enzyme gene insertion/deletion polymorphism and response to physical training. LANCET, 353(9152), 541 - 545.
    • Jansen H, Chu G, Ehnholm C, Dallongeville J, Nicaud V, Talmud PJ (1999). The T allele of the hepatic lipase promoter variant C-480T is associated with increased fasting lipids and HDL and increased preprandial and postprandial LpCIII:B : European Atherosclerosis Research Study (EARS) II. Arteriosclerosis, Thrombosis, and Vascular Biology, 19(2), 303 - 308.
    • Shea S, Isasi CR, Couch S, Starc TJ, Tracy RP, Deckelbaum R, Talmud P, Berglund L, Humphries SE (1999). Relations of plasma fibrinogen level in children to measures of obesity, the (G-455-->A) mutation in the beta-fibrinogen promoter gene, and family history of ischemic heart disease: the Columbia University BioMarkers Study.. Am J Epidemiol, 150(7), 737 - 746.
    • Waterworth DM, Cappuccio FP, Cook DG, Wicks PD, Humphries SE, Talmud PJ (1999). Variable effects of the ApoCIII C-482T variant on insulin and triglyceride levels in different ethnic groups.. AM J HUM GENET, 65(4), A471 - A471.
    • Talmud PJ, Waterworth DM (1999). Genetics and molecular biology.. Curr Opin Lipidol, 10(2), 181 - 183.

    1998

    • Humphries SE, Fisher RM, Miller G, Ye S, Henney A, Talmud PJ (1998). Predisposing genes, high-risk environments and coronary artery disease: LPL and MMP-3 as examples.
    • Talmud PJ, Palmen J, Walker M (1998). Identification of genetic variation in the human hormone-sensitive lipase gene and 5' sequences: homology of 5' sequences with mouse promoter and identification of potential regulatory elements. BIOCHEM BIOPHYS RES COMMUN, 252(3), 661 - 668.
    • Penno G, Chaturvedi N, Talmud PJ, Cotroneo P, Manto A, Nannipieri M, Luong LA, Fuller JH (1998). Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients: findings from the EUCLID Randomized Controlled Trial. EURODIAB Controlled Trial of Lisinopril in IDDM. DIABETES, 47(9), 1507 - 1511.
    • Humphries SE, Luong LA, Talmud PJ, Frick MH, Kesaniemi YA, Pasternack A, Taskinen MR, Syvanne M (1998). The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study. ATHEROSCLEROSIS, 139(1), 49 - 56.
    • Penno G, Chaturvedi N, Talmud PJ, Cotroneo P, Manto A, Nannipieri M, Luong LA, Fuller JH, EUCLID Study Grp (1998). Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients - Findings from the EUCLID randomized controlled trial. DIABETES, 47(9), 1507 - 1511.
    • Talmud PJ, Palmen J, Walker M (1998). Identification of genetic variation in the human hormone-sensitive lipase gene and 5' sequences: homology of 5' sequences with mouse promoter and identification of potential regulatory elements.. Biochem Biophys Res Commun, 252(3), 661 - 668. doi:10.1006/bbrc.1998.9597
    • Talmud PJ, Hall S, Holleran S, Ramakrishnan R, Ginsberg HN, Humphries SE (1998). LPL promoter -93T/G transition influences fasting and postprandial plasma triglycerides response in African-Americans and Hispanics. J LIPID RES, 39(6), 1189 - 1196.
    • Humphries SE, Luong LA, Talmud PJ, Frick MH, Kesaniemi YA, Pasternack A, Taskinen MR, Syvanne M (1998). The 5A/6A polymorphism in the promoter of the stromelysin-1 (MMP-3) gene predicts progression of angiographically determined coronary artery disease in men in the LOCAT gemfibrozil study. Lopid Coronary Angiography Trial. ATHEROSCLEROSIS, 139(1), 49 - 56.
    • Humphries SE, Nicaud V, Margalef J, Tiret L, Talmud PJ (1998). Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: the European Atherosclerosis Research Study (EARS). ARTERIOSCLER THROMB VASC BIOL, 18(4), 526 - 534.
    • Montgomery HE, Marshall R, Hemingway H, Myerson S, Clarkson P, Dollery C, Hayward M, Holliman DE, Jubb M, World M, Thomas EL, Brynes AE, Saeed N, Barnard M, Bell JD, Prasad K, Rayson M, Talmud PJ, Humphries SE (1998). Human gene for physical performance [letter]. NATURE, 393(6682), 221 - 222.
    • Austin MA, Talmud PJ, Luong LA, Haddad L, Day IN, Newman B, Edwards KL, Krauss RM, Humphries SE (1998). Candidate-gene studies of the atherogenic lipoprotein phenotype: a sib-pair linkage analysis of DZ women twins. The American Journal of Human Genetics, 62(2), 406 - 419.
    • Riches FM, Watts GF, van Bockxmeer FM, Hua J, Song S, Humphries SE, Talmud PJ (1998). Apolipoprotein B signal peptide and apolipoprotein E genotypes as determinants of the hepatic secretion of VLDL apoB in obese men. J LIPID RES, 39(9), 1752 - 1758.
    • Montgomery HE, Marshall R, Hemingway H, Myerson S, Clarkson P, Dollery C, Hayward M, Holliman DE, Jubb M, World M, Thomas EL, Brynes AE, Saeed N, Barnard M, Bell JD, Prasad K, Rayson M, Talmud PJ, Humphries SE (1998). Human gene for physical performance. NATURE, 393(6682), 221 - 222.
    • Flavell DM, Pineda-Torra I, Jamshidi Y, Evans D, Syvanne M, Taskinen MR, Humphries SE, Talmud PJ, Staels B (1998). Variation in the peroxisome proliferator activated receptor alpha gene is associated with plasma lipid concentrations, response to gemfibrozil and progression of atherosclerosis in coronary artery bypass graft patients.. CIRCULATION, 98(17), 532 - 532.
    • Talmud PJ, Martin SG, Humphries SE, Taskinen MR, Sturley SL, Syvanne M (1998). Genetic variation in the 3 ' flanking sequence of the alpha(1)-antitrypsin gene is associated with increased progression of atherosclerosis in the lopid coronary angiography trial (LOCAT).. CIRCULATION, 98(17), 459 - 459.
    • Talmud PJ, Bujac SR, Hall S, Humphries SE, Miller GJ (1998). LPL gene: Smoking interaction in the determination of ischaemic heart disease risk. ATHEROSCLEROSIS, 141(1), 182 - 182.

    1997

    • Montgomery HE, Clarkson P, Dollery CM, Prasad K, Losi MM, Hemingway H, Statters D, Jubb M, Girvain M, Varnava A, World M, Deanfield J, Talmud P, McEwan JR, McKenna WJ, Humphries S (1997). Association of angiotensin converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation, 96, 741 - 747.
    • Dallongeville J, Tiret L, Visvikis S, Talmud P, OReilly D, DeBacker G, Saava M, Tsitouris G, Beisiegel U (1997). Effect of apoE phenotype on postprandial triglycerides levels in young male with and without a familial history of myocardial infarction: The EARS II study. ATHEROSCLEROSIS, 134(1-2), 85 - 85.
    • Fisher RM, Humphries SE, Talmud PJ (1997). Common variation in the lipoprotein lipase gene: effects on plasma lipids and risk of atherosclerosis.. Atherosclerosis, 135(2), 145 - 159.
    • Fisher RM, Rawesh A, Talmud PJ, Coppack SW, Humphries SE (1997). Use of an intra-venous fat tolerance test to study in vivo the effect of common mutations in the lipoprotein lipase gene. ATHEROSCLEROSIS, 135(1), 16 - 16.
    • Talmud PJ, Hall S, Ramakrishnan S, Hollera S, Ginsberg H, Humphries SE (1997). LPL-93G promoter mutation influences both baseline plasma triglycerides and postprandial response in Black and Hispanics. ATHEROSCLEROSIS, 134(1-2), 72 - 73.
    • Talmud PJ, Margalef J, Turner P, Tiret L, Nicaud V, Humphries SE (1997). Variation in the LPL gene is associated with plasma TG concentrations and MI in the European Atherosclerosis Research Study (EARS). ATHEROSCLEROSIS, 134(1-2), 73 - 73.
    • Fisher RM, Rawesh A, Talmud PJ, Coppack SW, Humphries SE (1997). Use of an intra-venous fat tolerance test to study in vivo the effect of common mutations in the lipoprotein lipase gene. ATHEROSCLEROSIS, 134(1-2), 23 - 23.
    • Liu H, Xu C, Lins L, Ferrell R, Humphries SE, Talmud PJ (1997). Characterization and in vitro expression of a novel apolipoprotein CIII variant identified in individuals of Mayan Indian origin. ATHEROSCLEROSIS, 134(1-2), 70 - 70.
    • Humphries SE, Fisher R, Miller G, Ye S, Henney AM, Talmud PJ (1997). Predisposing genes, high-risk environments and coronary artery disease (CAD): Lipoprotein lipase (LPL) and stromelysin (MMP-3) as examples. ATHEROSCLEROSIS, 134(1-2), 291 - 291.
    • Humphries SE, Margalef J, Turner P, Tiret L, Nicaud V, Talmud PJ (1997). Variation in the LPL gene is associated with plasma TG concentrations and MI in the European Atherosclerosis Research Study (EARS).. ATHEROSCLEROSIS, 135(1), 10 - 10.
    • Benhizia F, Reina M, Sturley S, Vilaro S, Ginsberg H, Humphries S, Talmud P (1997). Variations in the human apolipoprotein B signal peptide alter apoB secretion and degradation in McArdle RH-7777 rat hepatoma cells. ATHEROSCLEROSIS, 134(1-2), 65 - 65.
    • Waterworth DM, Talmud P, Miller G, Humphries S (1997). Genetic variation in the apolipoprotein CIII gene and effects on plasma triglyceride levels in a large prospective study. ATHEROSCLEROSIS, 134(1-2), 75 - 75.
    • Hall S, Chu G, Miller G, Cruickshank K, Cooper JA, Humphries SE, Talmud PJ (1997). A common mutation in the lipoprotein lipase gene promoter, -93T/G, is associated with lower plasma triglyceride levels and increased promoter activity in vitro. ARTERIOSCLER THROMB VASC BIOL, 17(10), 1969 - 1976.
    • Syvanne M, Talmud PJ, Humphries SE, Fisher RM, Rosseneu M, Hilden H, Taskinen MR (1997). Determinants of postprandial lipemia in men with coronary artery disease and low levels of HDL cholesterol. J LIPID RES, 38(7), 1463 - 1472.
    • Gerdes C, Fisher RM, Nicaud V, Boer J, Humphries SE, Talmud PJ, Faergeman O (1997). Lipoprotein lipase variants D9N and N291S are associated with increased plasma triglyceride and lower high-density lipoprotein cholesterol concentrations: studies in the fasting and postprandial states: the European Atherosclerosis Research Studies. CIRCULATION, 96(3), 733 - 740.
    • Talmud PJ, Humphries SE (1997). Apolipoprotein C-III gene variation and dyslipidaemia. CURR OPIN LIPIDOL, 8(3), 154 - 158.
    • Mailly F, Palmen J, Muller DP, Gibbs T, Lloyd J, Brunzell J, Durrington P, Mitropoulos K, Betteridge J, Watts G, Lithell H, Angelico F, Humphries SE, Talmud PJ (1997). Familial lipoprotein lipase (LPL) deficiency: a catalogue of LPL gene mutations identified in 20 patients from the UK, Sweden, and Italy. HUM MUTAT, 10(6), 465 - 473.
    • Nemeth S, Talmud P, Grundy SM, Patel SB (1997). Activation of a cryptic splice-site in intron 24 leads to the formation of apolipoprotein B-27.6. ATHEROSCLEROSIS, 133(2), 163 - 170.
    • Yudkin JS, Andres C, Mohamed A, Gould M, Panahloo A, Haines AP, Humphries S, Talmud P (1997). The angiotensin-converting enzyme gene and the angiotensin II type I receptor gene as candidate genes for microalbuminuria. A study in nondiabetic and non-insulin-dependent diabetic subjects. ARTERIOSCLER THROMB VASC BIOL, 17(10), 2188 - 2191.
    • Heath KE, Luong LA, Leonard JV, Chester A, Shoulders CC, Scott J, Middleton P, Humphries SE, Talmud PJ (1997). The use of a highly informative CA repeat polymorphism within the abetalipoproteinaemia locus (4q22-24). PRENAT DIAGN, 17(12), 1181 - 1186.
    • Gerdes C, Fisher RM, Nicaud V, Boer J, Humphries SE, Talmud PJ, Faergeman O (1997). Lipoprotein lipase variants Asp9->Asn and Asp291->Ser are associated with increased plasma triglyceride and lower HDL cholesterol concentrations - Studies in the fasting and postprandial states. ATHEROSCLEROSIS, 134(1-2), 68 - 68.
    • Talmud P, Hall S, Chu G, Yudkin J, Miller G, Humphries S (1997). Lipoprotein lipase -93T/G transition is associated with lower plasma triglyceride levels and increased promoter activity in vitro.. ATHEROSCLEROSIS, 130, 76 - 76.

    1996

    • Humphries S, Fisher R, Mailly F, Peacock R, Talmud P, Karpe F, Hamsten A, Miller GJ (1996). Gene-environment interaction in determining plasma lipids and dietary response: The effect of common mutations in the gene for lipoprotein lipase (D9N and N291S).
    • Talmud P, Peacock R, Karpe F, Hamsten A, Humphries S (1996). Apo B genetic variants that modulate postprandial lipoprotein metabolism.
    • de Bruin TW, Mailly F, van Barlingen HH, Fisher R, Castro Cabezas M, Talmud P, Dallinga-Thie GM, Humphries SE (1996). Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia.. Eur J Clin Invest, 26(8), 631 - 639.
    • Gretch DG, Sturley SL, Wang L, Lipton BA, Dunning A, Grunwald KA, Wetterau JR, Yao Z, Talmud P, Attie AD (1996). The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness.. J Biol Chem, 271(15), 8682 - 8691.
    • Talmud P, Lins L, Brasseur R (1996). Prediction of signal peptide functional properties: a study of the orientation and angle of insertion of yeast invertase mutants and human apolipoprotein B signal peptide variants.. Protein Eng, 9(4), 317 - 321.
    • Montgomery HE, Clarkson P, Dollery C, Prasad K, Hemingway H, Kiernan L, Bishop G, Statters D, Talmud P, Humphries S, McKenna W, McEwan J (1996). The renin-angiotensin system and left ventricular hypertrophy: Rat and human studies.
    • Bagdade JD, Ritter MC, Lithell H, Bassett D, Mailly F, Talmud P, Hayden MR (1996). Reduced cholesteryl ester transfer in plasma of patients with lipoprotein lipase deficiency.. J Lipid Res, 37(8), 1696 - 1703.
    • Talmud PJ, Tamplin OJ, Heath K, Gaffney D, Day INM, Humphries SE (1996). Rapid testing for three mutations causing familial defective apolipoprotein B100 in 562 patients with familial hypercholesterolaemia. ATHEROSCLEROSIS, 125(1), 135 - 137.
    • Saha N, Talmud PJ, Tay JSH, Humphries SE, Basair J (1996). Lack of association of angiotensin-converting enzyme (ACE). Gene insertion/deletion polymorphism with CAD in two Asian populations. CLIN GENET, 50(3), 121 - 125.
    • Humphries SE, Talmud PJ, Cox C, Sutherland W, Mann J (1996). Genetic factors affecting the consistency and magnitude of changes in plasma cholesterol in response to dietary challenge.. QJM, 89(9), 671 - 680.
    • Talmud PJ, Hall S, Chu G, Ginsberg HN, Ramakrishnan R, Miller G, Humphries SE (1996). Lipoprotein lipase -93T/G transition is associated with lower plasma triglyceride levels and increases promoter activity in vitro. CIRCULATION, 94(8), 1587 - 1587.
    • Byrne CD, Wareham NJ, Mistry PK, Phillips DIW, Martensz ND, Halsall D, Talmud PJ, Humphries SE, Hales CN (1996). The association between free fatty acid concentrations and triglyceride-rich lipoproteins in the post-prandial state is altered by a common deletion polymorphism of the apo B signal peptide. ATHEROSCLEROSIS, 127(1), 35 - 42.
    • Mailly F, Fisher RM, Nicaud V, Luong LA, Evans AE, Marques-Vidal P, Luc G, Arveiler D, Bard JM, Poirier O, Talmud PJ, Humphries SE (1996). Association between the LPL-D9N mutation in the lipoprotein lipase gene and plasma lipid traits in myocardial infarction survivors from the ECTIM Study.. Atherosclerosis, 122(1), 21 - 28.

    1995

    • Turner PR, Talmud PJ, Visvikis S, Ehnholm C, Tiret L (1995). DNA polymorphisms of the apoprotein B gene are associated with altered plasma lipoprotein concentrations but not with perceived risk of cardiovascular disease: European Atherosclerosis Research Study.. Atherosclerosis, 116(2), 221 - 234.
    • YUDKIN JS, ANDRES C, MOHAMEDALI V, PANAHLOO A, HUMPHRIES S, TALMUD P (1995). THE DELETION POLYMORPHISM OF THE ANGIOTENSIN-CONVERTING ENZYME GENE IS NOT ASSOCIATED WITH MICROALBUMINURIA IN NON-INSULIN-DEPENDENT DIABETIC OR NONDIABETIC SUBJECTS. DIABETES, 44, A36 - A36.
    • PANAHLOO A, MOHAMEDALI Y, ANDRES C, TALMUD P, HUMPHREIS S, YUDKIN J (1995). THE DELETION ALLELE OF THE INSERTION DELETION POLYMORPHISM OF THE ACE GENE DOES NOT INCREASE CARDIOVASCULAR RISK THROUGH ASSOCIATION WITH THE INSULIN-RESISTANCE SYNDROME. DIABETES, 44, A234 - A234.
    • Talmud PJ, Watts GF, McBride S, Mandalia S, Brunt JN, Coltart DJ, Lewis B, Humphries SE (1995). Angiotensin converting enzyme gene polymorphism and the course of angiographically defined coronary artery disease.. Atherosclerosis, 114(1), 133 - 135.
    • MAILLY F, TUGRUL Y, REYMER PWA, BRUIN T, SEED M, GROENEMEYER BF, ASPLUNDCARLSON A, VALLANCE D, WINDER AF, MILLER GJ, KASTELEIN JJP, HAMSTEN A, OLIVECRONA G, HUMPHRIES SE, TALMUD PJ (1995). A COMMON VARIANT IN THE GENE FOR LIPOPROTEIN-LIPASE (ASP9-]ASN) - FUNCTIONAL IMPLICATIONS AND PREVALENCE IN NORMAL AND HYPERLIPIDEMIC SUBJECTS. ARTERIOSCL THROM VAS, 15(4), 468 - 478.
    • Humphries SE, Ye S, Talmud P, Bara L, Wilhelmsen L, Tiret L (1995). European Atherosclerosis Research Study: genotype at the fibrinogen locus (G-455-A beta-gene) is associated with differences in plasma fibrinogen levels in young men and women from different regions in Europe. Evidence for gender-genotype-environment interaction.. Arterioscler Thromb Vasc Biol, 15(1), 96 - 104.
    • Panahloo A, Andres C, Mohamed-Ali V, Gould MM, Talmud P, Humphries SE, Yudkin JS (1995). The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?. Circulation, 92(12), 3390 - 3393.
    • RAMAKRISHNAN R, TALMUD P, HUMPHRIES S, NGAI C, HOLLERAN S, BEGG M, GINSBERG HN (1995). RELATIONSHIP OF APOPROTEIN-B AND APOPROTEIN-CIII POLYMORPHISMS WITH POSTPRANDIAL LIPEMIA. CIRCULATION, 92(8), 2354 - 2354.
    • Fisher RM, Mailly F, Peacock RE, Hamsten A, Seed M, Yudkin JS, Beisiegel U, Feussner G, Miller G, Humphries SE, et AL (1995). Interaction of the lipoprotein lipase asparagine 291-->serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults.. The Journal of Lipid Research, 36(10), 2104 - 2112.
    • Humphries SE, Peacock RE, Talmud PJ (1995). The genetic determinants of plasma cholesterol and response to diet.. Baillieres Clin Endocrinol Metab, 9(4), 797 - 823.
    • Talmud P (1995). Bimonthly update in lipidology: Genetics and molecular biology.. Curr Opin Lipidol, 6(5), U120 - U123.
    • Humphries SE, Talmud PJ (1995). Hyperlipidaemia associated with genetic variation in the apolipoprotein B gene.. Curr Opin Lipidol, 6(4), 215 - 222.
    • CHATURVEDI N, TALMUD P, FULLER JH (1995). ANGIOTENSIN-CONVERTING ENZYME (ACE) GENE POLYMORPHISMS AND COMPLICATIONS IN INSULIN-DEPENDENT DIABETES-MELLITUS (IDDM). DIABETOLOGIA, 38, A227 - A227.
    • Peacock RE, Karpe F, Talmud PJ, Hamsten A, Humphries SE (1995). Common variation in the gene for apolipoprotein B modulates postprandial lipoprotein metabolism: a hypothesis generating study.. Atherosclerosis, 116(1), 135 - 145.
    • MONTGOMERY HE, KEELING PJ, GOLDMAN JH, HUMPHRIES SE, TALMUD PJ, MCKENNA WJ (1995). LACK OF ASSOCIATION BETWEEN THE INSERTION DELETION POLYMORPHISM OF THE ANGIOTENSIN-CONVERTING ENZYME GENE AND IDIOPATHIC DILATED CARDIOMYOPATHY. J AM COLL CARDIOL, 25(7), 1627 - 1631.

    1994

    • Powrie JK, Watts GF, Ingham JN, Taub NA, Talmud PJ, Shaw KM (1994). Role of glycaemic control in development of microalbuminuria in patients with insulin dependent diabetes.. BMJ, 309(6969), 1608 - 1612.
    • Xu CF, Talmud P, Schuster H, Houlston R, Miller G, Humphries S (1994). Association between genetic variation at the APO AI-CIII-AIV gene cluster and familial combined hyperlipidaemia.. Clin Genet, 46(6), 385 - 397.
    • STURLEY SL, TALMUD PJ, BRASSEUR R, CULBERTSON MR, HUMPHRIES SE, ATTIE AD (1994). HUMAN APOLIPOPROTEIN-B SIGNAL SEQUENCE VARIANTS CONFER A SECRETION-DEFECTIVE PHENOTYPE WHEN EXPRESSED IN YEAST. J BIOL CHEM, 269(34), 21670 - 21675.
    • SEED M, MAILLY F, VALLANCE D, DOHERTY E, WINDER A, TALMUD P, HUMPHRIES SE (1994). LIPOPROTEIN-LIPASE ACTIVITY IN PATIENTS WITH COMBINED HYPERLIPEMIA. CLIN INVESTIGATOR, 72(2), 100 - 106.
    • Talmud PJ, Krul ES, Pessah M, Gay G, Schonfeld G, Humphries SE, Infante R (1994). Donor splice mutation generates a lipid-associated apolipoprotein B-27.6 in a patient with homozygous hypobetalipoproteinemia.. J Lipid Res, 35(3), 468 - 477.
    • Talmud PJ, Ye S, Humphries SE (1994). Polymorphism in the promoter region of the apolipoprotein AI gene associated with differences in apolipoprotein AI levels: the European Atherosclerosis Research Study.. Genet Epidemiol, 11(3), 265 - 280. doi:10.1002/gepi.1370110305
    • Xu CF, Talmud P, Humphries S (1994). Three new polymorphisms of the ApoAI-CIII-AIV gene cluster.. Mol Cell Probes, 8(4), 331 - 332. doi:10.1006/mcpr.1994.1047

    1993

    • Humphries SE, Mailly F, Gudnason V, Talmud P (1993). The molecular genetics of pediatric lipid disorders: recent progress and future research directions.. Pediatr Res, 34(4), 403 - 415. doi:10.1203/00006450-199310000-00005
    • STURLEY SL, TALMUD PJ, BRASSEUR R, HUMPHRIES SJ, ATTIE AD (1993). HUMAN APOLIPOPROTEIN-B SIGNAL SEQUENCE VARIANTS CONFER A SECRETION DEFECTIVE PHENOTYPE WHEN EXPRESSED IN YEAST. CIRCULATION, 88(4), 177 - 177.
    • STURLEY SL, TALMUD PJ, HUMPHRIES SE, ATTIE AD (1993). A FUNCTIONAL ASSESSMENT OF INSERTION DELETION POLYMORPHISMS IN THE SIGNAL PEPTIDE OF HUMAN APOLIPOPROTEIN-B. J CELL BIOCHEM, , 10 - 10.
    • TAN K, BETTERIDGE DJ, MARMOT MG, TALMUD P, HUMPHRIES SE, YUDKIN JS (1993). HYPERTRIGLYCERIDEMIA AND VASCULAR RISK - REPORT OF A MEETING OF PHYSICIANS AND SCIENTISTS, UNIVERSITY-COLLEGE-LONDON MEDICAL-SCHOOL. LANCET, 342(8874), 781 - 787.
    • Dunning AM, Renges HH, Hamsten A, Talmud P, Humphries S (1993). A postulated phylogenetic tree for the human apolipoprotein B gene: unpredicted haplotypes are associated with elevated apo B levels.. Biochim Biophys Acta, 1165(3), 271 - 278.

    1992

    • Humphries SE, Dunning A, Xu CF, Peacock R, Talmud P, Hamsten A (1992). DNA polymorphism studies. Approaches to elucidating multifactorial ischaemic heart disease: the apo B gene as an example.. Ann Med, 24(5), 349 - 356.
    • Talmud PJ, Converse C, Krul E, Huq L, McIlwaine GG, Series JJ, Boyd P, Schonfeld G, Dunning A, Humphries S (1992). A novel truncated apolipoprotein B (apo B55) in a patient with familial hypobetalipoproteinemia and atypical retinitis pigmentosa.. Clin Genet, 42(2), 62 - 70.
    • Renges HH, Peacock R, Dunning AM, Talmud P, Humphries SE (1992). Genetic relationship between the 3'-VNTR and diallelic apolipoprotein B gene polymorphisms: haplotype analysis in individuals of European and south Asian origin.. Ann Hum Genet, 56(Pt 1), 11 - 33.
    • Talmud PJ, Boerwinkle E, Xu CF, Tikkanen MJ, Pietinen P, Huttunen JK, Humphries S (1992). Dietary intake and gene variation influence the response of plasma lipids to dietary intervention.. Genet Epidemiol, 9(4), 249 - 260. doi:10.1002/gepi.1370090404
    • DUNNING AM, RENGES HH, XU CF, PEACOCK R, BRASSEUR R, LAXER G, TIKKANEN MJ, BUTLER R, SAHA N, HAMSTEN A, ROSSENEU M, TALMUD P, HUMPHRIES SE (1992). 2 AMINO-ACID SUBSTITUTIONS IN APOLIPOPROTEIN-B ARE IN COMPLETE ALLELIC ASSOCIATION WITH THE ANTIGEN GROUP (X/Y) POLYMORPHISM - EVIDENCE FOR LITTLE RECOMBINATION IN THE 3' END OF THE HUMAN GENE. AM J HUM GENET, 50(1), 208 - 221.
    • Peacock R, Dunning A, Hamsten A, Tornvall P, Humphries S, Talmud P (1992). Apolipoprotein B gene polymorphisms, lipoproteins and coronary atherosclerosis: a study of young myocardial infarction survivors and healthy population-based individuals.. Atherosclerosis, 92(2-3), 151 - 164.
    • SCHONFELD G, PARHOFER KG, KRUL E, WAGNER RD, TALMUD P (1992). TRUNCATED FORMS OF APOLIPOPROTEIN-B AND HYPOBETALIPOPROTEINEMIA.

    1991

    • Talmud P, Tybjaerg-Hansen A, Bhatnagar D, Mbewu A, Miller JP, Durrington P, Humphries S (1991). Rapid screening for specific mutations in patients with a clinical diagnosis of familial hypercholesterolaemia.. Atherosclerosis, 89(2-3), 137 - 141.
    • Wagner RD, Krul ES, Tang J, Parhofer KG, Garlock K, Talmud P, Schonfeld G (1991). ApoB-54.8, a truncated apolipoprotein found primarily in VLDL, is associated with a nonsense mutation in the apoB gene and hypobetalipoproteinemia.. J Lipid Res, 32(6), 1001 - 1011.
    • Myant NB, Gallagher JJ, Knight BL, McCarthy SN, Frostegård J, Nilsson J, Hamsten A, Talmud P, Humphries SE (1991). Clinical signs of familial hypercholesterolemia in patients with familial defective apolipoprotein B-100 and normal low density lipoprotein receptor function.. Arterioscler Thromb, 11(3), 691 - 703.
    • Dunning AM, Houlston R, Frostegård J, Revill J, Nilsson J, Hamsten A, Talmud P, Humphries S (1991). Genetic evidence that the putative receptor binding domain of apolipoprotein B (residues 3130 to 3630) is not the only region of the protein involved in interaction with the low density lipoprotein receptor.. Biochim Biophys Acta, 1096(3), 231 - 237.
    • Mailly F, Xu CF, Xhignesse M, Lussier-Cacan S, Talmud PJ, Davignon J, Humphries SE, Nestruck AC (1991). Characterization of a new apolipoprotein E5 variant detected in two French-Canadian subjects.. J Lipid Res, 32(4), 613 - 620.
    • Xu CF, Talmud PJ, Angelico F, Del Ben M, Savill J, Humphries SE (1991). Apolipoprotein E polymorphism and plasma lipid, lipoprotein, and apolipoprotein levels in Italian children.. Genet Epidemiol, 8(6), 389 - 398. doi:10.1002/gepi.1370080605
    • Bruin T, Reymer PW, Groenemeyer BE, Talmud PJ, Kastelein JJ (1991). HindIII-polymorphism in the LPL-gene detected by PCR.. Nucleic Acids Res, 19(22), 6346 - .
    • RENGES H, PEACOCK R, DUNNING A, TALMUD P, HUMPHRIES S (1991). GENETIC-RELATIONSHIP BETWEEN DNA POLYMORPHISMS IN THE APOLIPO-PROTEIN-B (APO-B) GENE IN INDIVIDUALS OF EUROPEAN AND SOUTH ASIAN ORIGIN - POPULATION-GENETIC ASPECTS OF THE APO-B GENE VNTR SITE. AM J HUM GENET, 49(4), 14 - 14.
    • DUNNING A, RENGES H, XU C, PEACOCK R, TIKKANEN M, HAMSTEN A, TALMUD P, HUMPHRIES S (1991). MOLECULAR GENETIC-ANALYSIS OF THE APOLIPOPROTEIN-B ANTIGEN GROUP (X/Y) POLYMORPHISM. AM J HUM GENET, 49(4), 185 - 185.
    • HUMPHRIES S, DUNNING A, XU CF, TALMUD P (1991). STRATEGIES TO IDENTIFY COMMON, FUNCTIONALLY IMPORTANT SEQUENCE POLYMORPHISMS IN THE APO-B-GENE.

    1990

    • WAGNER D, KRUL E, TANG JJ, TALMUD P, HUMPHRIES S, SCHONFELD G (1990). A NEW TRUNCATED FORM OF APOLIPOPROTEIN-B IN A KINDRED WITH HYPOBETALIPOPROTEINEMIA - APO-B-54.8. CIRCULATION, 82(4), 424 - 424.
    • DUNNING A, HANSEN AT, GALLAGHER J, VINCENT J, HOULSTON RS, TALMUD PJ, SEED M, HAMSTEN A, MYANT N, HUMPHRIES SE (1990). FAMILIAL DEFECTIVE APOLIPOPROTEIN B-100 - DETECTION AND CLINICAL CHARACTERISTICS. J MED GENET, 27(10), 649 - 649.
    • WAGNER D, KRUL E, TANG JG, TALMUD P, HUMPHRIES S, SCHONFELD G (1990). A NEW TRUNCATED FORM OF APOLIPOPROTEIN-B IN A KINDRED WITH HYPOBETALIPOPROTEINEMIA - APO-B-54.8. ARTERIOSCLEROSIS, 10(5), A771 - A771.
    • Xu CF, Nanjee MN, Savill J, Talmud PJ, Angelico F, Del Ben M, Antonini R, Mazzarella B, Miller N, Humphries SE (1990). Variation at the apolipoprotein (apo) AI-CIII-AIV gene cluster and apo B gene loci is associated with lipoprotein and apolipoprotein levels in Italian children.. Am J Hum Genet, 47(3), 429 - 439.
    • Xu CF, Tikkanen MJ, Huttunen JK, Pietinen P, Bütler R, Humphries S, Talmud P (1990). Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.. J Lipid Res, 31(7), 1255 - 1261.
    • SCHONFELD G, KRUL ES, TALMUD P, DAUGHERTY A, HUMPHRIES SE (1990). HYPOBETALIPOPROTEINEMIA ASSOCIATED WITH 2 TRUNCATED FORMS OF APO-B IN A USA KINDRED.
    • DUNNING AM, KINGUNDERWOOD L, HOULSTON R, TALMUD PJ, HUMPHRIES SE (1990). STRATEGIES FOR DETECTION OF SINGLE BASE CHANGES IN SUBJECTS HETEROZYGOUS FOR ALLELES OF THE APOLIPOPROTEIN-B GENE. J MED GENET, 27(3), 206 - 207.
    • Menzel HJ, Dieplinger H, Lackner C, Hoppichler F, Lloyd JK, Muller DR, Labeur C, Talmud PJ, Utermann G (1990). Abetalipoproteinemia with an ApoB-100-lipoprotein(a) glycoprotein complex in plasma. Indication for an assembly defect.. J Biol Chem, 265(2), 981 - 986.
    • Tybjaerg-Hansen A, Gallagher J, Vincent J, Houlston R, Talmud P, Dunning AM, Seed M, Hamsten A, Humphries SE, Myant NB (1990). Familial defective apolipoprotein B-100: detection in the United Kingdom and Scandinavia, and clinical characteristics of ten cases.. Atherosclerosis, 80(3), 235 - 242.
    • Xu CF, Boerwinkle E, Tikkanen MJ, Huttunen JK, Humphries SE, Talmud PJ (1990). Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change.. Genet Epidemiol, 7(4), 261 - 275. doi:10.1002/gepi.1370070405
    • Tikkanen MJ, Xu CF, Hämäläinen T, Talmud P, Sarna S, Huttunen JK, Pietinen P, Humphries S (1990). XbaI polymorphism of the apolipoprotein B gene influences plasma lipid response to diet intervention.. Clin Genet, 37(5), 327 - 334.

    1989

    • XU C, NANJEE N, TIKKANEN MJ, HUTTUNEN JK, PIETINEN P, BUTLER R, ANGELICO F, DELBEN M, MAZZARELLA B, ANTONIO R, MILLER NG, HUMPHRIES S, TALMUD PJ (1989). APOLIPOPROTEIN-B AMINO ACID-3611 SUBSTITUTION FROM ARGININE TO GLUTAMINE CREATES THE AG (H/I) EPITOPE - THE POLYMORPHISM IS NOT ASSOCIATED WITH DIFFERENCES IN SERUM-CHOLESTEROL AND APOLIPOPROTEIN-B LEVELS. HUM GENET, 82(4), 322 - 326.
    • Humphries S, Talmud P, Monsalve V, McKeigue P (1989). RFLP studies in different ethnic groups.. Atherosclerosis, 75(2-3), 249 - 250.
    • HUMPHRIES S, DUNNING A, TYBJERGHANSEN A, TALMUD P (1989). THE USE OF MOLECULAR-BIOLOGY TECHNIQUES TO ANALYZE A MULTIFACTORIAL TRAIT - ATHEROSCLEROSIS AS AN EXAMPLE.
    • Talmud P, King-Underwood L, Krul E, Schonfeld G, Humphries S (1989). The molecular basis of truncated forms of apolipoprotein B in a kindred with compound heterozygous hypobetalipoproteinemia.. J Lipid Res, 30(11), 1773 - 1779.
    • TYBJAERGHANSEN A, GALLAGHER J, VINCENT J, HOULSTON R, TALMUD P, SEED M, HUMPHRIES S, MYANT N (1989). SCREENING FOR THE APO B(ARG3500-]GLN) MUTATION. ATHEROSCLEROSIS, 79(1), 93 - 93.
    • Krul ES, Kinoshita M, Talmud P, Humphries SE, Turner S, Goldberg AC, Cook K, Boerwinkle E, Schonfeld G (1989). Two distinct truncated apolipoprotein B species in a kindred with hypobetalipoproteinemia.. Arteriosclerosis, 9(6), 856 - 868.

    1988

    • Talmud PJ, Lloyd JK, Muller DP, Collins DR, Scott J, Humphries S (1988). Genetic evidence from two families that the apolipoprotein B gene is not involved in abetalipoproteinemia.. J Clin Invest, 82(5), 1803 - 1806. doi:10.1172/JCI113795
    • TALMUD PJ, HOULSTON R, DUNNING A, DEMANT T, SERIES J, PACKARD C, SHEPHERD J, HUMPHRIES S (1988). APOLIPOPROTEIN-B GENE POLYMORPHISMS IN NORMAL AND HYPERLIPEMIC INDIVIDUALS. J CLIN CHEM CLIN BIO, 26(5), 327 - 328.
    • COLLINS DR, KNOTT TJ, PEASE RJ, POWELL LM, WALLIS SC, ROBERTSON S, PULLINGER CR, MILNE RW, MARCEL YL, HUMPHRIES SE, TALMUD PJ, LLOYD JK, MILLER NE, MULLER D, SCOTT J (1988). TRUNCATED VARIANTS OF APOLIPOPROTEIN-B CAUSE HYPOBETALIPOPROTEINEMIA. NUCLEIC ACIDS RES, 16(17), 8361 - 8375.
    • Dunning AM, Talmud P, Humphries SE (1988). Errors in the polymerase chain reaction.. Nucleic Acids Res, 16(21), 10393 - .

    1987

    • MONSALVE MV, TALMUD PJ, KAY A, WISEMAN S, POWELL J, GREENHALGH R, HUMPHRIES SE (1987). CORRELATION BETWEEN RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISMS OF APOLIPOPROTEIN-B AND SERUM-LIPID LEVELS IN PATIENTS WITH PERIPHERAL AND CORONARY ARTERIAL DISEASES. BIOCHEM SOC T, 15(4), 629 - 631.
    • Klasen EC, Talmud PJ, Havekes L, de Wit E, van der Kooij-Meijs E, Smit M, Hansson G, Humphries SE (1987). A common restriction fragment length polymorphism of the human apolipoprotein E gene and its relationship to type III hyperlipidaemia.. Hum Genet, 75(3), 244 - 247.
    • HOULSTON RS, HUTSON JL, HASSALL D, TALMUD P, LEWIS B, HUMPHRIES SE (1987). A COMPARISON OF THE EFFECT OF GENETIC-VARIATION IN THE GENES FOR APO-B AND APO-E IN THE DETERMINATION OF NORMAL PLASMA-LIPID LIPOPROTEIN CONCENTRATIONS. ATHEROSCLEROSIS, 68(3), 274 - 274.
    • Talmud PJ, Barni N, Kessling AM, Carlsson P, Darnfors C, Bjursell G, Galton D, Wynn V, Kirk H, Hayden MR (1987). Apolipoprotein B gene variants are involved in the determination of serum cholesterol levels: a study in normo- and hyperlipidaemic individuals.. Atherosclerosis, 67(1), 81 - 89.
    • Humphries SE, Talmud PJ, Kessling AM (1987). Use of DNA polymorphisms of the apolipoprotein genes to study the role of genetic variation in the determination of serum lipid levels.. Ciba Found Symp, 130, 128 - 149.

    1986

    • Darnfors C, Nilsson J, Protter AA, Carlsson P, Talmud PJ, Humphries SE, Whalström J, Wiklund O, Bjursell G (1986). RFLPs for the human apolipoprotein B gene: HincII and PvuII.. Nucleic Acids Res, 14(17), 7135 - .
    • Talmud P, Humphries S (1986). DNA polymorphisms and the apolipoprotein B gene.. Lancet, 2(8498), 104 - .
    • Barni N, Talmud PJ, Carlsson P, Azoulay M, Darnfors C, Harding D, Weil D, Grzeschik KH, Bjursell G, Junien C (1986). The isolation of genomic recombinants for the human apolipoprotein B gene and the mapping of three common DNA polymorphisms of the gene--a useful marker for human chromosome 2.. Hum Genet, 73(4), 313 - 319.

    1985

    • Pope FM, Nicholls AC, McPheat J, Talmud P, Owen R (1985). Collagen genes and proteins in osteogenesis imperfecta.. J Med Genet, 22(6), 466 - 478.
    • TALMUD PJ, AZOULAY M, JUNIEN C, CARLSSON P, WEIL D, GRZESCHIK KH, BJURSELL G, WILLIAMSON R, HUMPHRIES SE (1985). 2 DNA POLYMORPHISMS OF THE HUMAN APOLIPOPROTEIN-B GENE - A USEFUL MARKER FOR HUMAN CHROMOSOME-2. CYTOGENET CELL GENET, 40(1-4), 759 - 759.
    • TALMUD PJ, HORSTHEMKE B, DUNNING A, WILLIAMSON R, KESSLING A, HUMPHRIES SE (1985). DNA POLYMORPHISM OF THE LOW-DENSITY LIPOPROTEIN (LDL) RECEPTOR GENE - A USEFUL LINKAGE MARKER FOR CHROMOSOME-19. CYTOGENET CELL GENET, 40(1-4), 760 - 760.
    • DAVISON PJ, NORTON P, WALLIS S, DAVIS L, COOK M, GILL L, WILLIAMSON R, TALMUD PJ, HUMPHRIES SE (1985). THE GENES FOR APOLIPOPROTEIN-E (APOE) AND APOCL ARE LESS THAN 15KB APART ON HUMAN CHROMOSOME-19. CYTOGENET CELL GENET, 40(1-4), 614 - 614.

    1981

    • Cairns J, Robins P, Sedgwick B, Talmud P (1981). The inducible repair of alkylated DNA.. Prog Nucleic Acid Res Mol Biol, 26, 237 - 244.

    1977

    • Talmud PJ (1977). Mutational synergism between p-fluorophenylalanine and UV in Coprinus lagopus.. Mutat Res, 43(2), 213 - 222.

    1974

    • Talmud P, Lewis D (1974). Mutagenicity of amino acid analogues in eukaryotes.. Nature, 249(457), 563 - 564.
    • Talmud PJ, Lewis D (1974). The mutagenicity of amino acid analogues in Coprinus lagopus.. Genet Res, 23(1), 47 - 61.

    1973

    • TALMUD PJ, LEWIS D (1973). AMINO-ACID ANALOGS AS MUTAGENS IN EUKARYOTES/S. GENETICS, 74(JUN), S270 - S270.
    • TALMUD PJ, LEWIS D (1973). AMINO-ACID ANALOGS AS MUTAGENS IN EUKARYOTES/S. HEREDITY, 31(AUG), 139 - 139.

    • Gertow K, Sennblad B, Strawbridge R, Ohrvik J, Zabeneh D, Shah S, Veglia F, Fava C, Kavousi M, Kivimaki M, Bolton J, Fokersen L, Gigante B, Leander K, Vikstrom M, Larsson , Silveira A, Deanfield J, Voight BF, Fontanillas P, Sabater-Lleal M, Colombo G, Kumari M, Langenberg C, Wareham N, Uitterlinder A, Gabrielsen A, Hedin U, Franco-Cereceda A, Nyyssoen K, Rauramaa R, Tuomainen T, Savonen K, Smit A, Giral P, Mannarino E, Robertson C, Talmud PJ, Hedblad B, Hofman A, Erdmann J, Reilly MP, Grazia Franzosi MG, Seedorf U, Syvanen AC, Hansson GK, Eriksson P, Samani NJ, Watkins H, Price JF, Hingorani AD, Melander O, Witterman JCM, Baldassaree D, Tremoli E, de Faire U, Hamsten A, Humphries SE (). Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-medial thickness and coronary artery disease. Circulation: Cardiovascular Genetics, , - .
    • Vaessen SF, Schaap FG, Kuivenhoven JA, Groen AK, Hutten BA, Boekholdt SM, Hattori H, Sandhu MS, Bingham SA, Luben R, Palmen JA, Wareham NJ, Humphries SE, Kastelein JJ, Talmud PJ, Khaw KT (). Apolipoprotein av, triglycerides and risk of future coronary artery disease in apparently healthy men and women; the prospective epic-norfolk population study.. The Journal of Lipid Research, , - .
    • Talmud PJ, Hingorani AD, Cooper JA, Marmot MG, Brunner EJ, Kumari M, Kivimäki M, Humphries SE (). Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.. British Medical Journal, , - .