Dr Marc Serfaty

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Personal Profile

Name: Marc Serfaty Email: m.serfaty@ucl.ac.uk
Title: Dr Tel: +44 (0) 20 7679 9712
Department: Division of Psychiatry Fax: +44 (0) 20 7679 9426
Position: Reader in Psychiatry Address: Charles Bell House, 67-73 Riding House Street, London, W1W 7EJ
Research Domain: Neuroscience, Populations & Lifelong Health Web Page: Personal Web Page

Profile

Research Description

Dr Serfaty has undertaken a number of funded RCTs using CBT in a variety of groups, especially those who may be neglected from receiving help; older people, cancer patients, eating disorders, people with intellectual disabilities and those with Body Dysmorphic Disorder and victims of crime.

Dr Serfaty's was one of the first people to test CBT for anorexia nervosa and findings informed NICE guidelines. He also explored whether CBT, delivered by email would be helpful in bulimia nervosa and binge eating disorder. He pioneered the first RCT to compare CBT with a complementary therapy called aromatherapy massage. His internationally recognised trial of CBT in older people, demonstrated that not only was individual CBT effective in this group, but dispelled the prejudice that you cannot teach an old dog new tricks, by demonstrating an improvement was not attributed to common, non specific factors in therapy, but rather specific CBT techniques. Other work includes, the Helping Aged Victims of Crime (HAVoC) study, investigating the impact of crime on older people and whether a cognitive behaviourally based Victim Improvement Package (VIP).  Results appear promising with more work planned. Dr Serfaty has conducted pilot work with Dr Hassiotis (UCL) determining how CBT, using a more cognitive elements than previously researched, could be delivered to people with Intellectual Difficulties. This study generated promising results. Dr Serfaty worked with Dr Veale to investigate the use of CBT in Body Dysmorphic Disorder.

Currently Dr Serfaty is leading on a national UK study investigating the clinical and cost effectiveness of CBT in people with advanced cancer and depression. Finally, now that he has trained as a therapist in Acceptance and Commitment Therapy (ACT), he will be leading a trial piloting a third wave CBT, ACT in people with cancer in palliative care. Further research is planned in neurology, older victims of crime and generalised anxiety disorder.

Dr Serfaty's interest in melatonin and sleep disturbance arose from a clinical Doctorate (MD Res); “The use of melatonin for sleep disturbance in dementia and depression depression”. The first trial was the first randomised trial to investigate the use of slow release melatonin 5mg orally, in people with dementia and sleep disturbance, using wrist actigraphy as an objective measure of sleep. This cross-over design demonstrated a more robust method of investigating the effects of melatonin.  Even though findings were negative, it was an important challenge to proponents for the use of melatonin.  Another RCT using slow release melatonin 5mg, in people in depression, suggests that melatonin, which is not subject to patent, may be antidepressant and that it may be as effective as melatonin agonists, currently being promoted by a number of pharmaceutical companies.


Research Activities

CanTalk: the clinical and cost effectiveness of CBT plus treatment as usual for the treatment of depression in cancer; a randomised trial.

Development of manualised CBT for adults with mild learning disabilities & anxiety or depression.

HAVoC study: determining the psychosocial effects of crime on older people and the development of a trial of Treatment As Usual (TAU) versus a Victim Improvement Package (VIP).

Health services research including mixed methods evaluation of interventions for people with intellectual disabilities (ID) and mental health problems

The addition of ACT or a Talking Control to treatment as usual for the management of dysfunction in advanced cancer: a feasibility randomised controlled trial

Education Description

Dr Serfaty is an accredited teacher and Fellow of Higher Education Academy (FHEA).

Post graduate teaching: (i) 1996-2006. He set up and organized the MRCPsych Academic training programme for post graduate psychiatric trainees. The training programme was developed to be consistent with the syllabus detailed by the Royal college of psychiatrists and was regarded as one of the best academic training programmes for psychiatry in the UK which achieved consistently high pass rates on the theory papers for candidates sitting the MRCPsych exam. Elements of this are still used as the template for the MRCPsych course at UCL. (ii) He wasresponsible for the psychotherapy academic programme on the MRCPsych course, where he introduced novel and up to date psychotherapeutic interventions onto the training programme, including interventions such as Acceptance and Commitment Therapy (ACT). (iii) He has consistently achieved extremely high ratings for teaching on the MRCPsych course, with comments such as exhilarating and best lecture this year.

Undergraduate teaching: (iv) Dr Serfaty is the academic tutor for 4 medical students sent to the Priory Hospital North London from the UCL medical student rotation, having set up the undergraduate training package for medical students, which has consistently received high ratings through independent on line feedback.

Dr Serfaty has a liaison role between UCL and Priory group, an independent health care provider. Delivering medical education in Primary care: He conducts regular lectures in primary care to GPs and to GP training schemes on behalf of UCL and PHNL. Talks have included seminars on CBT for depression, anxiety and panic, CBT for Cancer, Sleep problems, CBT for eating disorders and obesity, Acceptance and Commitment therapy (ACT) and work related stress. These seminars consistently achieve high ratings and disseminate findings from research at UCL.

UCL Collaborators

Prof Michael King; Dr Andre Strydom; Dr Angela Hassiotis

External Collaborators

Publications

    2013

    • Hassiotis A, Serfaty M, Azam K, Strydom A, Blizard R, Romeo R, Martin S, King M (2013). Manualised Individual Cognitive Behavioural Therapy for mood disorders in people with mild to moderate intellectual disability: A feasibility randomised controlled trial. Journal of Affective Disorders, , - .

    2012

    • SERFATY MA, Wilkinson S, Freeman C, Mannix K, King M (2012). The ToT Study: Helping with Touch or Talk (ToT): a pilot randomised controlled trial to examine the clinical effectiveness of aromatherapy massage versus cognitive behaviour therapy for emotional distress in patients in cancer/palliative care.. Psychooncology, 21, 563 - 569.
    • Serfaty MA, Raven PW (2012). Could melatonin be a more suitable alternative to synthetic melatonin agonists?. Lancet, 379, 217 - 217.
    • Veale D, Ellison N, Werner TG, Dodhia R, Serfaty MA, Clarke A (2012). Development of a Cosmetic Procedure Screening Questionnaire (COPS) for Body Dysmorphic Disorder.. J Plast Reconstr Aesthet Surg, 65(4), 530 - 532. doi:10.1016/j.bjps.2011.09.007

    2011

    • Hassiotis A, Serfaty MA, Azam K, Strydom M, King M, Martin S, Parkes C, Blizard R (2011). Cognitive behaviour therapy (CBT) for anxiety and depression in adults with mild intellectual disabilities (ID): a pilot randomised controlled trial.. Trails, 12, 95 - . doi:10.1186/1745-6215-12-95
    • Veale D, Ellison N, Werner TG, Dodhia R, Serfaty MA, Clarke A (2011). Development of a Cosmetic Procedure Screening Questionnaire (COPS) for Body Dysmorphic Disorder. Journal of Plastic, Reconstructive & Aesthetic Surgery, 64(4), 530 - 532.
    • Low JTS, Davis S, Drake R, King M, Tookman A, Turner K, Serfaty M, Leurent B, Jones L (2011). The role of acceptance in rehabilitation in life threatening illness.. Journal of Pain and Symptom Management, 43, 20 - 28.
    • Serfaty MA (2011). Its good to talk, or is it?.
    • Holman AJ, Serfaty MA, Leurent BE, King MB (2011). Cost-effectiveness of cognitive behaviour therapy versus talking and usual care for depressed older people in primary care.. BMC Health Serv Res, 11, 33 - . doi:10.1186/1472-6963-11-33
    • Serfaty MA, Csipke C, Haworth D, Murad S, King M (2011). A Talking Control for use in evaluating the effectiveness of Cognitive Behavioral Therapy. BRAT, 49, 433 - 440.
    • SERFATY M, Wilkinson S, Mannix K, Freeman C, King MB (2011). ) The ToT Study: Helping with Touch or Talk (ToT ): a pilot randomised controlled trial to examine the clinical effectiveness of aromatherapy massage versus cognitive behaviour therapy for emotional distress in patients in cancer/palliative care.. Psycho-oncology, , - .
    • Serfaty MA (2011). The clinical effectiveness of individual cognitive behaviour therapy for depressed older people in primary care and the use of a talking control (TC).

    2010

    • Azam K, Hassiotis A, King M, Serfaty M, Parkes C, Strydom A, Martin S, Blizard R (2010). A literature review of CBT treatment in people with mild to moderate ID. J APPL RES INTELLECT, 23(5), 425 - 425.
    • Serfaty MA, Osborne D, Buszewicz MJ, Blizard R, Raven PW (2010). A randomized double-blind placebo-controlled trial of treatment as usual plus exogenous slow-release melatonin (6 mg) or placebo for sleep disturbance and depressed mood.. Int Clin Psychopharmacol, 25(3), 132 - 142. doi:10.1097/YIC.0b013e32832c260b
    • Holt S, SERFATY M (2010). Larger studies of melatonin for depression/sleep needed. Focus on Alternative and Complementary Therapies, 15(4), 317 - 318.

    2009

    • Serfaty MA, Haworth D, Blanchard M, Buszewicz M, Murad S, King M (2009). Clinical effectiveness of individual cognitive behavioral therapy for depressed older people in primary care: a randomized controlled trial. Arch Gen Psychiatry, 66(12), 1332 - 1340. doi:10.1001/archgenpsychiatry.2009.165
    • Blanchard M, Serfaty M, Duckett S, Flately S (2009). Adapting services for a changing society: a reintegrative model for old age psychiatry (based on a model proposed by Knight and Emanuel, 2007).. Int J Geriatr Psychiatry, 24(2), 202 - 206. doi:10.1002/gps.2083
    • Serfaty MA, Haworth D, Blanchard M, Buszewicz M, Murad S, King M (2009). Clinical effectiveness of individual cognitive behavioral therapy for depressed older people in primary care: a randomized controlled trial.. Arch Gen Psychiatry, 66(12), 1332 - 1340. doi:10.1001/archgenpsychiatry.2009.165

    2008

    • Robinson PH, Serfaty M (2008). Getting better byte by byte: a pilot randomised controlled trial of email therapy for bulimia nervosa and binge eating disorder. European Eating Disorders Review, 16(2), 84 - 93.

    2007

    • King M, Dinos S, Serfaty M, Weich S, Stevens S (2007). Measuring Stigma. British Journal of Psychiatry, 191, 364 - . doi:10.1192/bjp.191.4.364
    • King MB, dinos S, Serfaty M, Weich S, Stevens S (2007). Authors reply.
    • King M, Dinos S, Shaw JW, R Stevens S, Passetti F, Weich S, Serfaty M (2007). The Stigma Scale: development of a standardised measure of the stigma of mental illness. The British Journal of Psychiatry, 190, 248 - 254.

    2006

    • Csipke E, Serfaty M, Buszewicz M (2006). Optimizing recruitment from primary care: methods of recruiting older people with depression. Primary Health Care Research and Development, 7(2), 116 - 123.
    • Serfaty M (2006). MD thesis: The Use of melatonin in depression and dementia.

    2004

    • Warner J, Pitts N, Crawford MJ, Serfaty M, Prabhakaran P, Amin R (2004). Sexual activity among patients in psychiatric hospital wards. Journal of the Royal Society of Medicine, 97(10), 477 - 479.
    • Dinos S, Stevens S, Serfaty M, Weich S, King M (2004). Stigma: the feelings and experiences of 46 people with mental illness. Qualitative study. The British Journal of Psychiatry, 184, 176 - 181.

    2003

    • Serfaty MA, Osborne D, Buszewicz MJ, Raven PW (2003). The effect of Exogeneous Melatonin in Major Depression. Chronobiology International, 20(6), 1191 - 1192.
    • McKenzie K, Serfaty M, Crawford M (2003). Suicide in ethnic minority groups. The British Journal of Psychiatry, 183(2), 100 - 101.
    • Robinson P, Serfaty M (2003). Computers, e-mail and therapy in eating disorders. European Eating Disorders Review, 11(3), 210 - 221.

    2002

    • Serfaty MA, Bothwell R, Marsh R, Ashton H, Blizard R, Scott J (2002). Event-related potentials and cognitive processing of affectively toned words in depression. Journal Of Psychophysiology, 16(1), 56 - 66.
    • Serfaty MA, Bothwell R, Marsh R, Ashton H, Blizard R, Scott J (2002). Event-related potentials and cognitive processing of affectively toned words in depression. J PSYCHOPHYSIOL, 16(1), 56 - 66. doi:10.1027//0269-8803.16.1.56
    • Serfaty M, Kennell-Webb S, Warner J, Blizard R, Raven P (2002). Double blind randomised placebo controlled trial of low dose melatonin for sleep disorders in dementia. International Journal of Geriatric Psychiatry, 17(12), 1120 - 1127.

    2001

    • Robinson PH, Serfaty MA (2001). The use of e-mail in the identification of bulimia nervosa and its treatment. European Eating Disorders Review, 9(3), 182 - 193.

    2000

    • Serfaty M, Clark D (2000). Cognitive behaviour psychotherapy. In Maxwell H (Ed.), Psychotherapy (pp. - ). : .

    1999

    • Serfaty MA, Turkington D, Heap M, Ledsham L, Jolley E (1999). Cognitive thereapy versus dietary counselling in the outpatient treatment of anorexia nervosa: effects of the treatment phase. European Eating Disorders Review, 7(1), 334 - 350.

    1998

    • Serfaty M, McCluskey S (1998). Compulsory treatment for anorexia nervosa and the moribund patient. European Eating Disorders Review, 6(1), 27 - 37.

    1997

    • Serfaty MA, Lawrie A, Smith B, Brind AM, Watson JP, Gilvarry E, Bassendine MF (1997). Risk factors and medical follow-up of drug users tested for hepatitis C--can the risk of transmission be reduced?. Drug Alcohol Rev, 16(4), 339 - 347. doi:10.1080/09595239700186721
    • Serfaty MA, Lawrie A, Smith B, Brind AM, Watson JP, Gilvarry E, Bassendine MF (1997). Risk factors and medical follow-up of drug users tested for hepatitis C. Can the risk of transmission be reduced?. Drug and Alcohol Review, 16, 333 - 347.

    1996

    • Brind AM, Serfaty MA, Lawrie A, Watson JP, Johnson S, Gilvarry E, Bassendine MF (1996). Hepatitis C virus (HCV) infection in a drug dependency centre in North East England.. HEPATOLOGY, 23(1), P102 - P102.
    • Serfaty MA, Martin LM, Lingham R, Ferrier IN (1996). The effect of psychotropic medication on seizure duration during bilateral electroconvulsive therapy: a retrospective study. Journal of Psychopharmacology, 10(4), 303 - 308.

    1995

    • Serfaty MA, McCluskey S, Eccleston D (1995). A case of extreme suicidality following serotonin syndrome. The British Journal of Psychiatry, 167, 410 - .
    • Lawrie A, Serfaty MA, Smith C (1995). Is residential psychiatric on call justified?. Psychiatric Bulletin, 20(1), 12 - 14.
    • Serfaty MA, McCluskey S, Eccleston D (1995). Extreme suicidality following serotonin syndrome.. Br J Psychiatry, 167(3), 410 - .
    • BRIND AM, SERFATY MA, LAWRIE A, WATSON JP, JOHNSON S, GILVARRY E, BASSENDINE MF (1995). ASSESSMENT AND MEDICAL FOLLOW-UP OF INTRAVENOUS-DRUG-USERS (IVDU) POSITIVE FOR HEPATITIS-C VIRUS (HCV) IN NORTH-EAST ENGLAND. HEPATOLOGY, 22(4), 1114 - 1114.

    1993

    • Serfaty M, Masterton G (1993). Fatal poisonings attributed to benzodiazepines in Britain during the 1980s. The British Journal of Psychiatry, 163, 386 - 393.

    1992

    • Serfaty MA (1992). Benzodiazepine attributed deaths in Great Britain during the decade 1980-1989.

    • Moorey S, Serfaty MA (). Cascading to IAPT; the CanTalk trial.
    • SERFATY M, Csipke E, Haworth D, Murad S (). A Talking Control for use in evaluating the effectiveness of Cognitive Behavioral Therapy. Behavior Research and Therapy, In press, - .
    • Serfaty MA (). Helping Aged Vcitms of Crime (HAVoC) study; The impact of common crime on older people and the feasibility of a cognitive behavioural therapy (CBT) based intervention..
    • Azam K, Serfaty MA, King M, Martin S, Strydom A, Parkes C, Hassiotis A (). The development of manualised cognitive behaviour treatment for adults with mild intellectual disability and common mental disorders. Psychiatrike, 23, 109 - 116.
    • Serfaty MA, Vincent L (). Individual manualised Cognitive Behavioural Therapy for Common Mental Disorders in People with Intellectual Disability.
    • Azam K, Serfaty MA, King M, Martin S, Strydom A, Parkes C (). The development of manualised cognitive behaviour treatment for adults with mild intellectual disability and common mental disorders.. Psychiatrike, 23, 109 - 116.
    • Serfaty MA, Jones L, King M, Nazareth I, Tookman A, Pilling S, White N, Hore B (). The clinical and cost effectiveness of CBT plus treatment as usual for the treatment of depression in advanced cancer: a randomised controlled trial (The CanTalk Study); the feasibility phase..